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Search results 1 to 100 out of 636 for Idh1

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
3417 | IDH1
Type: gene
Organism: human
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Gene
424112 | IDH1
Type: gene
Organism: chicken
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Gene
100006589 | idh1
Type: gene
Organism: zebrafish
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Gene
710019 | IDH1
Type: gene
Organism: macaque, rhesus
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Gene
448164 | idh1
Type: gene
Organism: frog, western clawed
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Gene
478889 | IDH1
Type: gene
Organism: dog, domestic
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Gene
460113 | IDH1
Type: gene
Organism: chimpanzee
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Gene
281235 | IDH1
Type: gene
Organism: cattle
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Gene
key_20598 | IDH1
Type: gene
Organism: cat, domestic
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Gene
key_18916 | IDH1
Type: gene
Organism: sheep
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Gene
key_20081 | IDH1
Type: gene
Organism: gorilla, western
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Gene
24479 | Idh1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:96413 | Idh1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
644051 | IDH1P1
Type: gene
Organism: human
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Gene
100507475 | IDH1-AS1
Type: gene
Organism: human
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Publication
29719265 | J:270804
First Author: Philip B
Year: 2018
Journal: Cell Rep
Title: Mutant IDH1 Promotes Glioma Formation In Vivo.
Volume: 23
Issue: 5
Pages: 1553-1564
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Publication
25218477 | J:215544
 
First Author: Bogdanovic E
Year: 2014
Journal: Neurosci Lett
Title: IDH1 regulates phospholipid metabolism in developing astrocytes.
Volume: 582
Pages: 87-92
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Publication
36410274 | J:332203
 
First Author: Zhao Q
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Mutant IDH1 attenuates hepatic lipogenesis through PTEN dependent pathway.
Volume: 637
Pages: 254-258
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GXD Expression
GXD Expression
     
Probe: MGI:4354297
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:4354796
Age: embryonic day 14.5
Specimen Label: Table S5 - Idh1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4354297
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354796
Age: embryonic day 14.5
Note: Expression is present in the upper and lower cortical plate.
Specimen Label: Table S5 - Idh1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4354297
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354796
Age: embryonic day 14.5
Specimen Label: Table S5 - Idh1
Detected: true
Specimen Num: 1
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Publication
28465358 | J:243294
First Author: Amankulor NM
Year: 2017
Journal: Genes Dev
Title: Mutant IDH1 regulates the tumor-associated immune system in gliomas.
Volume: 31
Issue: 8
Pages: 774-786
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Publication
23558169 | J:198193
First Author: Rohle D
Year: 2013
Journal: Science
Title: An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.
Volume: 340
Issue: 6132
Pages: 626-30
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Publication
22925884 | J:187697
First Author: Sasaki M
Year: 2012
Journal: Genes Dev
Title: D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.
Volume: 26
Issue: 18
Pages: 2038-49
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Publication
28011762 | J:239546
First Author: Ye J
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: IDH1 deficiency attenuates gluconeogenesis in mouse liver by impairing amino acid utilization.
Volume: 114
Issue: 2
Pages: 292-297
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Publication
33254233 | J:303804
First Author: Gu Y
Year: 2021
Journal: Blood
Title: IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis.
Volume: 137
Issue: 7
Pages: 945-958
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Publication
25882048 | J:258539
First Author: Itsumi M
Year: 2015
Journal: Cell Death Differ
Title: Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.
Volume: 22
Issue: 11
Pages: 1837-45
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Publication
27424808 | J:234913
First Author: Inoue S
Year: 2016
Journal: Cancer Cell
Title: Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.
Volume: 30
Issue: 2
Pages: 337-348
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Publication
28148827 | J:241022
First Author: Pirozzi CJ
Year: 2017
Journal: Mol Cancer Res
Title: Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression.
Volume: 15
Issue: 5
Pages: 507-520
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Publication
26787889 | J:229965
First Author: Hao Z
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Idh1 mutations contribute to the development of T-cell malignancies in genetically engineered mice.
Volume: 113
Issue: 5
Pages: 1387-92
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Strain
MGI:2161211 | STOCK Idh1
Attribute String: mutant stock
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HT Experiment
GSE123130 | RNA sequencing on primary murine chondrocytes expressing mutant Idh1
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
34848557 | J:321567
First Author: Wu MJ
Year: 2022
Journal: Cancer Discov
Title: Mutant IDH Inhibits IFNγ-TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma.
Volume: 12
Issue: 3
Pages: 812-835
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Publication
37267108 | J:337994
First Author: Pathmanapan S
Year: 2023
Journal: Cell Rep
Title: Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation.
Volume: 42
Issue: 6
Pages: 112578
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Publication
31391185 | J:280025
First Author: Zhang Y
Year: 2019
Journal: Cancer Res
Title: Mutant IDH Sensitizes Gliomas to Endoplasmic Reticulum Stress and Triggers Apoptosis via miR-183-Mediated Inhibition of Semaphorin 3E.
Volume: 79
Issue: 19
Pages: 4994-5007
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Publication
32855525 | J:296229
First Author: Yang R
Year: 2020
Journal: Oncogene
Title: Isocitrate dehydrogenase 1 mutation enhances 24(S)-hydroxycholesterol production and alters cholesterol homeostasis in glioma.
Volume: 39
Issue: 40
Pages: 6340-6353
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Publication
36652477 | J:333482
First Author: Fortin J
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells.
Volume: 120
Issue: 4
Pages: e2208176120
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Publication
27956631 | J:239062
First Author: Lemonnier F
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.
Volume: 113
Issue: 52
Pages: 15084-15089
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Publication
22763442 | J:186700
First Author: Sasaki M
Year: 2012
Journal: Nature
Title: IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics.
Volume: 488
Issue: 7413
Pages: 656-9
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Publication
32035087 | J:291969
 
First Author: Kang HS
Year: 2020
Journal: Metabolism
Title: IDH1-dependent α-KG regulates brown fat differentiation and function by modulating histone methylation.
Volume: 105
Pages: 154173
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Publication
1914521 | J:441
First Author: Yasue M
Year: 1991
Journal: Cytogenet Cell Genet
Title: Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids.
Volume: 57
Issue: 2-3
Pages: 142-8
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Publication
29097607 | J:253871
First Author: Waitkus MS
Year: 2018
Journal: Cancer Res
Title: Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities.
Volume: 78
Issue: 1
Pages: 36-50
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Publication
34048454 | J:306194
First Author: Ghimire S
Year: 2021
Journal: PLoS One
Title: PEG3 controls lipogenesis through ACLY.
Volume: 16
Issue: 5
Pages: e0252354
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Publication
35921412 | J:327421
First Author: Gupta S
Year: 2022
Journal: Sci Adv
Title: Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis.
Volume: 8
Issue: 31
Pages: eabn4886
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Publication
22975371 | J:192908
First Author: Shih AH
Year: 2012
Journal: Cancer Cell
Title: IDH1 mutations disrupt blood, brain, and barriers.
Volume: 22
Issue: 3
Pages: 285-7
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Protein Coding Gene
MGP_CAROLIEiJ_G0014220 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016108 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016091 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016048 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016046 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0015877 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96413 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016499 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0015850 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0015951 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0015954 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016023 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0015974 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016546 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015247 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015523 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027458 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015027 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9866202 | J:51393
First Author: Nekrutenko A
Year: 1998
Journal: Mol Biol Evol
Title: Cytosolic isocitrate dehydrogenase in humans, mice, and voles and phylogenetic analysis of the enzyme family.
Volume: 15
Issue: 12
Pages: 1674-84
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Publication
12031902 | J:79887
First Author: Lee SM
Year: 2002
Journal: Free Radic Biol Med
Title: Cytosolic NADP(+)-dependent isocitrate dehydrogenase status modulates oxidative damage to cells.
Volume: 32
Issue: 11
Pages: 1185-96
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Publication
25730874 | J:220318
First Author: Hirata M
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Mutant IDH is sufficient to initiate enchondromatosis in mice.
Volume: 112
Issue: 9
Pages: 2829-34
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Publication
35985343 | J:328532
First Author: Shi DD
Year: 2022
Journal: Cancer Cell
Title: De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma.
Volume: 40
Issue: 9
Pages: 939-956.e16
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Publication
- | J:14301
 
First Author: Sweet HO
Year: 1991
Journal: Mouse Genome
Title: Greige (ge).
Volume: 89
Pages: 258-9
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Publication
5233460 | J:5050
First Author: Mintz B
Year: 1967
Journal: Proc Natl Acad Sci U S A
Title: Normal mammalian muscle differentiation and gene control of isocitrate dehydrogenase synthesis.
Volume: 58
Issue: 2
Pages: 592-8
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Publication
5019139 | J:5265
First Author: Epstein CJ
Year: 1972
Journal: Dev Biol
Title: The expression of the isocitrate dehydrogenase locus (ld-1) during mouse embryogenesis.
Volume: 27
Issue: 3
Pages: 430-3
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Publication
876380 | J:5837
First Author: Epstein CJ
Year: 1977
Journal: Nature
Title: Gene dosage for isocitrate dehydrogenase in mouse embryos trisomic for chromosome 1.
Volume: 267
Issue: 5612
Pages: 615-6
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Publication
6601005 | J:7007
First Author: Opalka B
Year: 1983
Journal: Eur J Immunol
Title: Evidence for a new lymphocyte-stimulating determinant (Lsd) detected by alloreactive T cell lines.
Volume: 13
Issue: 1
Pages: 24-30
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Publication
2443579 | J:8850
First Author: Harada YN
Year: 1987
Journal: J Immunogenet
Title: A gene locus controlling a serum protein migrating electrophoretically in the beta region of mice and detected by using a strain derived from the Japanese wild mouse (Mus musculus molossinus).
Volume: 14
Issue: 1
Pages: 33-41
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Publication
15254034 | J:93352
First Author: Koh HJ
Year: 2004
Journal: J Biol Chem
Title: Cytosolic NADP+-dependent isocitrate dehydrogenase plays a key role in lipid metabolism.
Volume: 279
Issue: 38
Pages: 39968-74
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Publication
14327193 | J:13010
 
First Author: HENDERSON NS
Year: 1965
Journal: J Exp Zool
Title: ISOZYMES OF ISOCITRATE DEHYDROGENASE: SUBUNIT STRUCTURE AND INTRACELLULAR LOCATION.
Volume: 158
Pages: 263-73
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Publication
19106211 | J:145716
First Author: Kim J
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Role of cytosolic NADP+-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney.
Volume: 296
Issue: 3
Pages: F622-33
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Publication
22542506 | J:193000
First Author: Nam WS
Year: 2012
Journal: Biochim Biophys Acta
Title: RNA interference targeting cytosolic NADP(+)-dependent isocitrate dehydrogenase exerts anti-obesity effect in vitro and in vivo.
Volume: 1822
Issue: 8
Pages: 1181-8
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Publication
27693047 | J:236867
First Author: Bardella C
Year: 2016
Journal: Cancer Cell
Title: Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis.
Volume: 30
Issue: 4
Pages: 578-594
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GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6437547
Age: postnatal month 2
Specimen Label: Brain Adult
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6437547
Age: embryonic day 13.5
Specimen Label: Brain E13.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:6437547
Age: postnatal month 2
Specimen Label: MG
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6437547
Age: postnatal month 2
Specimen Label: SM
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6437547
Age: postnatal month 2
Specimen Label: Liver
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6437547
Age: postnatal month 2
Specimen Label: Kid
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6437547
Age: postnatal month 2
Specimen Label: Spleen
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6437547
Age: postnatal month 2
Specimen Label: Lung
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6437521
Assay Type: RT-PCR
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6437548
Age: postnatal month 2
Specimen Label: Brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6437521
Assay Type: RT-PCR
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6437548
Age: postnatal month 2
Specimen Label: Liver
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6437521
Assay Type: RT-PCR
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6437548
Age: postnatal month 2
Specimen Label: Muscle
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6437521
Assay Type: RT-PCR
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:6437548
Age: postnatal month 2
Specimen Label: Adipose
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6437521
Assay Type: RT-PCR
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Stage: TS17
Assay Id: MGI:6437549
Age: embryonic day 10.5
Specimen Label: E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6437521
Assay Type: RT-PCR
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6437549
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6437521
Assay Type: RT-PCR
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437549
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6437521
Assay Type: RT-PCR
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6437549
Age: postnatal month 2
Specimen Label: Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6437551
Age: postnatal month 2
Specimen Label: Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Stage: TS17
Assay Id: MGI:6437551
Age: embryonic day 10.5
Specimen Label: E10.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6437551
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6437520
Assay Type: Western blot
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437551
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6780727
Assay Type: RT-PCR
Annotation Date: 2021-10-20
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:6780738
Age: postnatal adult
Image: 5
Specimen Label: WT-F1
Detected: true
Specimen Num: 1
•
•
•
•
•




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