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Search results 1 to 100 out of 174 for Ifih1

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0.023s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Oda H
Year: 2014
Journal: Am J Hum Genet
Title: Aicardi-Goutières syndrome is caused by IFIH1 mutations.
Volume: 95
Issue: 1
Pages: 121-5
Publication
First Author: Lincez PJ
Year: 2015
Journal: Diabetes
Title: Reduced expression of the MDA5 Gene IFIH1 prevents autoimmune diabetes.
Volume: 64
Issue: 6
Pages: 2184-93
Publication
First Author: Crampton SP
Year: 2012
Journal: J Immunol
Title: Ifih1 gene dose effect reveals MDA5-mediated chronic type I IFN gene signature, viral resistance, and accelerated autoimmunity.
Volume: 188
Issue: 3
Pages: 1451-9
Publication
First Author: Gorman JA
Year: 2017
Journal: Nat Immunol
Title: The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.
Volume: 18
Issue: 7
Pages: 744-752
Publication
First Author: Dou Y
Year: 2017
Journal: EMBO J
Title: The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation.
Volume: 36
Issue: 18
Pages: 2742-2757
Publication
First Author: Soda N
Year: 2019
Journal: J Immunol
Title: Singleton-Merten Syndrome-like Skeletal Abnormalities in Mice with Constitutively Activated MDA5.
Volume: 203
Issue: 5
Pages: 1356-1368
Publication
First Author: Kato H
Year: 2006
Journal: Nature
Title: Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.
Volume: 441
Issue: 7089
Pages: 101-5
Publication
First Author: Bajad P
Year: 2020
Journal: Nucleic Acids Res
Title: An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype.
Volume: 48
Issue: 6
Pages: 3286-3303
Publication      
First Author: Onizawa H
Year: 2020
Journal: Int Immunol
Title: Aicardi-Goutières syndrome-like encephalitis in mutant mice with constitutively active MDA5.
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Kovacsovics M
Year: 2002
Journal: Curr Biol
Title: Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation.
Volume: 12
Issue: 10
Pages: 838-43
Publication
First Author: Züst R
Year: 2011
Journal: Nat Immunol
Title: Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.
Volume: 12
Issue: 2
Pages: 137-43
Publication
First Author: Jin YH
Year: 2012
Journal: J Virol
Title: Melanoma differentiation-associated gene 5 is critical for protection against Theiler's virus-induced demyelinating disease.
Volume: 86
Issue: 3
Pages: 1531-43
Publication
First Author: Zalinger ZB
Year: 2015
Journal: J Virol
Title: MDA5 Is Critical to Host Defense during Infection with Murine Coronavirus.
Volume: 89
Issue: 24
Pages: 12330-40
Publication
First Author: Gitlin L
Year: 2010
Journal: PLoS Pathog
Title: Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo.
Volume: 6
Issue: 1
Pages: e1000734
Publication
First Author: Tamassia N
Year: 2008
Journal: J Immunol
Title: Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils.
Volume: 181
Issue: 9
Pages: 6563-73
Publication
First Author: Motz C
Year: 2013
Journal: Science
Title: Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling.
Volume: 339
Issue: 6120
Pages: 690-3
Publication
First Author: De Miranda J
Year: 2009
Journal: FASEB J
Title: Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5.
Volume: 23
Issue: 4
Pages: 1064-71
Publication
First Author: Berke IC
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: MDA5 assembles into a polar helical filament on dsRNA.
Volume: 109
Issue: 45
Pages: 18437-41
Publication
First Author: Wu J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality.
Volume: 111
Issue: 4
Pages: E511-20
Publication    
First Author: Kang DC
Year: 2002
Journal: GenBank Submission
Title: Mus musculus strain C57BL/6J melanoma differentiation associated gene 5-like protein mRNA, complete cds
Pages: AF374384
Publication    
First Author: Strausberg R
Year: 2002
Journal: GenBank Submission
Title: Mus musculus, simialr to RIKEN cDNA 9130009C22 gene, clone IMAGE: 3990931, mRNA, partial cds
Pages: BC019605
Publication
First Author: Kitai Y
Year: 2015
Journal: J Biol Chem
Title: Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.
Volume: 290
Issue: 2
Pages: 1269-80
Publication
First Author: Berke IC
Year: 2012
Journal: EMBO J
Title: MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA.
Volume: 31
Issue: 7
Pages: 1714-26
Publication
First Author: Hu MM
Year: 2017
Journal: J Exp Med
Title: Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5.
Volume: 214
Issue: 4
Pages: 973-989
Publication
First Author: Kato H
Year: 2008
Journal: J Exp Med
Title: Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5.
Volume: 205
Issue: 7
Pages: 1601-10
Publication
First Author: Lu HL
Year: 2013
Journal: J Immunol
Title: Melanoma differentiation-associated gene 5 senses hepatitis B virus and activates innate immune signaling to suppress virus replication.
Volume: 191
Issue: 6
Pages: 3264-76
Publication
First Author: Kasumba DM
Year: 2017
Journal: J Immunol
Title: A Plant-Derived Nucleic Acid Reconciles Type I IFN and a Pyroptotic-like Event in Immunity against Respiratory Viruses.
Volume: 199
Issue: 7
Pages: 2460-2474
Publication  
First Author: Nakahama T
Year: 2018
Journal: EMBO Rep
Title: ADAR1-mediated RNA editing is required for thymic self-tolerance and inhibition of autoimmunity.
Volume: 19
Issue: 12
Publication
First Author: Liddicoat BJ
Year: 2015
Journal: Science
Title: RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself.
Volume: 349
Issue: 6252
Pages: 1115-20
Publication
First Author: Wies E
Year: 2013
Journal: Immunity
Title: Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.
Volume: 38
Issue: 3
Pages: 437-49
Publication
First Author: Deng X
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages.
Volume: 114
Issue: 21
Pages: E4251-E4260
Publication
First Author: Lang X
Year: 2017
Journal: J Exp Med
Title: TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity.
Volume: 214
Issue: 2
Pages: 459-473
Publication
First Author: Flür K
Year: 2009
Journal: Am J Pathol
Title: Viral RNA induces type I interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene-5: Implications for viral infection-associated glomerulonephritis.
Volume: 175
Issue: 5
Pages: 2014-22
Publication
First Author: Broquet AH
Year: 2011
Journal: J Immunol
Title: RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium.
Volume: 186
Issue: 3
Pages: 1618-26
Publication
First Author: Goubau D
Year: 2014
Journal: Nature
Title: Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates.
Volume: 514
Issue: 7522
Pages: 372-375
Publication
First Author: Duewell P
Year: 2014
Journal: Cell Death Differ
Title: RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8(+) T cells.
Volume: 21
Issue: 12
Pages: 1825-37
Publication
First Author: Wang Q
Year: 2011
Journal: PLoS Pathog
Title: MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness.
Volume: 7
Issue: 5
Pages: e1002070
Publication
First Author: McCartney SA
Year: 2008
Journal: PLoS Pathog
Title: MDA-5 recognition of a murine norovirus.
Volume: 4
Issue: 7
Pages: e1000108
Publication
First Author: Wang Y
Year: 2010
Journal: J Immunol
Title: Cutting edge: polyinosinic:polycytidylic acid boosts the generation of memory CD8 T cells through melanoma differentiation-associated protein 5 expressed in stromal cells.
Volume: 184
Issue: 6
Pages: 2751-5
Publication
First Author: Jelinek I
Year: 2011
Journal: J Immunol
Title: TLR3-specific double-stranded RNA oligonucleotide adjuvants induce dendritic cell cross-presentation, CTL responses, and antiviral protection.
Volume: 186
Issue: 4
Pages: 2422-9
Publication
First Author: Veazey JM
Year: 2019
Journal: PLoS One
Title: Distinct roles for MDA5 and TLR3 in the acute response to inhaled double-stranded RNA.
Volume: 14
Issue: 5
Pages: e0216056
Publication
First Author: Harris ML
Year: 2018
Journal: PLoS Biol
Title: A direct link between MITF, innate immunity, and hair graying.
Volume: 16
Issue: 5
Pages: e2003648
Publication
First Author: Zhong X
Year: 2020
Journal: PLoS Pathog
Title: ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response.
Volume: 16
Issue: 4
Pages: e1008457
Publication
First Author: Satoh T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.
Volume: 107
Issue: 4
Pages: 1512-7
Publication
First Author: Loo YM
Year: 2008
Journal: J Virol
Title: Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity.
Volume: 82
Issue: 1
Pages: 335-45
Publication
First Author: Zhao C
Year: 2017
Journal: Cell Rep
Title: The E3 Ubiquitin Ligase TRIM40 Attenuates Antiviral Immune Responses by Targeting MDA5 and RIG-I.
Volume: 21
Issue: 6
Pages: 1613-1623
Publication
First Author: McCartney S
Year: 2009
Journal: J Exp Med
Title: Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells.
Volume: 206
Issue: 13
Pages: 2967-76
Publication
First Author: Gitlin L
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus.
Volume: 103
Issue: 22
Pages: 8459-64
Publication
First Author: Shaheen ZR
Year: 2019
Journal: Am J Physiol Regul Integr Comp Physiol
Title: CCR5 is a required signaling receptor for macrophage expression of inflammatory genes in response to viral double-stranded RNA.
Volume: 316
Issue: 5
Pages: R525-R534
Publication
First Author: Kozaki T
Year: 2015
Journal: Int Immunol
Title: Role of zinc-finger anti-viral protein in host defense against Sindbis virus.
Volume: 27
Issue: 7
Pages: 357-64
Publication
First Author: Chiang HS
Year: 2014
Journal: Nat Immunol
Title: GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses.
Volume: 15
Issue: 1
Pages: 63-71
Publication
First Author: Anz D
Year: 2009
Journal: J Immunol
Title: Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus.
Volume: 182
Issue: 10
Pages: 6044-50
Publication
First Author: Vongpipatana T
Year: 2020
Journal: J Immunol
Title: ADAR1 Regulates Early T Cell Development via MDA5-Dependent and -Independent Pathways.
Volume: 204
Issue: 8
Pages: 2156-2168
Publication
First Author: Gibbert K
Year: 2010
Journal: J Immunol
Title: Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease.
Volume: 185
Issue: 10
Pages: 6179-89
Publication
First Author: Chattopadhyay S
Year: 2010
Journal: EMBO J
Title: Viral apoptosis is induced by IRF-3-mediated activation of Bax.
Volume: 29
Issue: 10
Pages: 1762-73
Publication
First Author: Wang X
Year: 2020
Journal: J Immunol
Title: MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus.
Volume: 205
Issue: 11
Pages: 3058-3070
Publication
First Author: Anz D
Year: 2010
Journal: J Immunol
Title: Immunostimulatory RNA blocks suppression by regulatory T cells.
Volume: 184
Issue: 2
Pages: 939-46
Publication
First Author: Menachery VD
Year: 2014
Journal: J Virol
Title: Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.
Volume: 88
Issue: 8
Pages: 4251-64
Publication
First Author: Funabiki M
Year: 2014
Journal: Immunity
Title: Autoimmune disorders associated with gain of function of the intracellular sensor MDA5.
Volume: 40
Issue: 2
Pages: 199-212
Publication
First Author: Choi MK
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.
Volume: 106
Issue: 42
Pages: 17870-5
Publication
First Author: Yoneyama M
Year: 2005
Journal: J Immunol
Title: Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity.
Volume: 175
Issue: 5
Pages: 2851-8
Publication
First Author: Costa Cruz PH
Year: 2020
Journal: RNA
Title: A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing.
Volume: 26
Issue: 4
Pages: 454-469
Publication
First Author: McCartney SA
Year: 2011
Journal: J Clin Invest
Title: RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice.
Volume: 121
Issue: 4
Pages: 1497-507
Publication
First Author: Pantel A
Year: 2014
Journal: PLoS Biol
Title: Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation.
Volume: 12
Issue: 1
Pages: e1001759
Publication
First Author: Ruane D
Year: 2013
Journal: J Exp Med
Title: Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract.
Volume: 210
Issue: 9
Pages: 1871-88
Publication
First Author: Swanson CL
Year: 2010
Journal: J Exp Med
Title: Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.
Volume: 207
Issue: 7
Pages: 1485-500
Publication
First Author: DeWitte-Orr SJ
Year: 2010
Journal: PLoS Pathog
Title: An accessory to the 'Trinity': SR-As are essential pathogen sensors of extracellular dsRNA, mediating entry and leading to subsequent type I IFN responses.
Volume: 6
Issue: 3
Pages: e1000829
Publication
First Author: Pham AM
Year: 2016
Journal: PLoS Pathog
Title: PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.
Volume: 12
Issue: 3
Pages: e1005489
Publication
First Author: Ernst P
Year: 2004
Journal: Dev Cell
Title: Definitive hematopoiesis requires the mixed-lineage leukemia gene.
Volume: 6
Issue: 3
Pages: 437-43
Publication
First Author: Tzeng HT
Year: 2014
Journal: PLoS One
Title: Tumor necrosis factor-alpha induced by hepatitis B virus core mediating the immune response for hepatitis B viral clearance in mice model.
Volume: 9
Issue: 7
Pages: e103008
Publication
First Author: Valaperti A
Year: 2013
Journal: Circulation
Title: Innate immune interleukin-1 receptor-associated kinase 4 exacerbates viral myocarditis by reducing CCR5(+) CD11b(+) monocyte migration and impairing interferon production.
Volume: 128
Issue: 14
Pages: 1542-54
Publication
First Author: Saito T
Year: 2008
Journal: Nature
Title: Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA.
Volume: 454
Issue: 7203
Pages: 523-7
Publication
First Author: Chalk AM
Year: 2019
Journal: Genome Biol
Title: The majority of A-to-I RNA editing is not required for mammalian homeostasis.
Volume: 20
Issue: 1
Pages: 268
Publication
First Author: Linehan MM
Year: 2018
Journal: Sci Adv
Title: A minimal RNA ligand for potent RIG-I activation in living mice.
Volume: 4
Issue: 2
Pages: e1701854
Publication
First Author: McWilliams IL
Year: 2019
Journal: Cell Rep
Title: Pseudovirus rVSVΔG-ZEBOV-GP Infects Neurons in Retina and CNS, Causing Apoptosis and Neurodegeneration in Neonatal Mice.
Volume: 26
Issue: 7
Pages: 1718-1726.e4
Publication
First Author: Miyashita M
Year: 2011
Journal: Mol Cell Biol
Title: DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling.
Volume: 31
Issue: 18
Pages: 3802-19
Publication
First Author: Bankers L
Year: 2020
Journal: J Immunol
Title: Development of IFN-Stimulated Gene Expression from Embryogenesis through Adulthood, with and without Constitutive MDA5 Pathway Activation.
Volume: 204
Issue: 10
Pages: 2791-2807