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Search results 1 to 84 out of 84 for Ift25

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
51668 | IFT25
Type: gene
Organism: human
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Gene
733760 | ift25
Type: gene
Organism: frog, western clawed
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Gene
685284 | Ift25
Type: gene
Organism: rat
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Gene
456868 | IFT25
Type: gene
Organism: chimpanzee
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Gene
616194 | IFT25
Type: gene
Organism: cattle
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Gene
100683945 | IFT25
Type: gene
Organism: dog, domestic
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Gene
714791 | IFT25
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR033558 | IFT25
Type: Family
Description: Intraflagellar transport (IFT) is the bidirectional movement of multimeric protein particles, termed IFT particles, between the cell body and the distal tip of a flagellum. IFT particle proteins are thought to serve as scaffolds to facilitate the attachment of cargo proteins to IFT motors, mediating the transport of flagellar precursors []. The main constituents of IFT particles are organized into two protein complexes, A and B.IFT25 is a component of the intraflagellar transport (IFT) complex B. It directly interacts with IFT27, forming a subcomplex that may be involved in the regulation of IFT [, ]. IFT25 is required for Hedgehog signalling in cilia [].
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Protein Coding Gene
MGI:1920188 | Ift25
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22595669 | J:184749
First Author: Keady BT
Year: 2012
Journal: Dev Cell
Title: IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.
Volume: 22
Issue: 5
Pages: 940-51
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Publication
19253336 | J:154656
First Author: Follit JA
Year: 2009
Journal: Cell Motil Cytoskeleton
Title: Characterization of mouse IFT complex B.
Volume: 66
Issue: 8
Pages: 457-68
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Publication
19412537 | -
First Author: Wang Z
Year: 2009
Journal: PLoS One
Title: Intraflagellar transport (IFT) protein IFT25 is a phosphoprotein component of IFT complex B and physically interacts with IFT27 in Chlamydomonas.
Volume: 4
Issue: 5
Pages: e5384
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Protein
Q9D6H2
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: false
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Publication
29626631 | J:260436
     
First Author: Desai PB
Year: 2018
Journal: Mech Dev
Title: Ift25 is not a cystic kidney disease gene but is required for early steps of kidney development.
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Publication
28964737 | J:251964
First Author: Zhang Y
Year: 2017
Journal: Dev Biol
Title: Intraflagellar transporter protein (IFT27), an IFT25 binding partner, is essential for male fertility and spermiogenesis in mice.
Volume: 432
Issue: 1
Pages: 125-139
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Publication
14718520 | -
First Author: Qin H
Year: 2004
Journal: J Cell Biol
Title: Intraflagellar transport (IFT) cargo: IFT transports flagellar precursors to the tip and turnover products to the cell body.
Volume: 164
Issue: 2
Pages: 255-66
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Publication
25446516 | J:215449
First Author: Eguether T
Year: 2014
Journal: Dev Cell
Title: IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.
Volume: 31
Issue: 3
Pages: 279-90
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Publication
26023097 | J:224085
First Author: Yang N
Year: 2015
Journal: Development
Title: Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis.
Volume: 142
Issue: 12
Pages: 2194-202
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Publication
28430876 | J:245566
First Author: Liu H
Year: 2017
Journal: Biol Reprod
Title: IFT25, an intraflagellar transporter protein dispensable for ciliogenesis in somatic cells, is essential for sperm flagella formation.
Volume: 96
Issue: 5
Pages: 993-1006
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Protein Coding Gene
MGP_CAROLIEiJ_G0026249 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028536 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028499 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028446 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028232 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1920188 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027668 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028349 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028317 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028450 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028994 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027749 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028582 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027218 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:6781689
Assay Type: RT-PCR
Annotation Date: 2021-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673015
Stage: TS15
Assay Id: MGI:6781735
Age: embryonic day 9.5
Specimen Label: pSHF
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6781689
Assay Type: RT-PCR
Annotation Date: 2021-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6781735
Age: embryonic day 9.5
Specimen Label: embryo
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6690816
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1796524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6690857
Age: embryonic day 16.5
Image: 3A E16.5
Note: Mainly expressed at the pre-follicle formation stage.
Specimen Label: 3A E16.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6690816
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1796527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6690857
Age: postnatal day 0
Image: 3A P0
Specimen Label: 3A P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6690816
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1796527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6690857
Age: postnatal day 3
Image: 3A P3
Specimen Label: 3A P3
Detected: true
Specimen Num: 3
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Publication
33351795 | J:299510
First Author: Wang JJ
Year: 2020
Journal: PLoS Biol
Title: Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice.
Volume: 18
Issue: 12
Pages: e3001025
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Publication
28576874 | J:247118
First Author: Monis WJ
Year: 2017
Journal: J Cell Biol
Title: BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia.
Volume: 216
Issue: 7
Pages: 2131-2150
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Publication
24596149 | J:215956
 
First Author: Ishikawa H
Year: 2014
Journal: Elife
Title: TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.
Volume: 3
Pages: e01566
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Publication
26980730 | J:234200
First Author: Katoh Y
Year: 2016
Journal: J Biol Chem
Title: Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex.
Volume: 291
Issue: 21
Pages: 10962-75
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Publication
27340223 | J:237132
First Author: Burnicka-Turek O
Year: 2016
Journal: Hum Mol Genet
Title: Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
Volume: 25
Issue: 14
Pages: 3011-3028
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Publication
- | J:175213
     
First Author: Lo C
Year: 2011
Journal: MGI Direct Data Submission (B2B/CvDC)
Title: Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC)
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Ift25<tm1c(EUCOMM)Wtsi> | MGI:6151138
Name: intraflagellar transport 25; targeted mutation 1c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready
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Publication
21505417 | -
First Author: Bhogaraju S
Year: 2011
Journal: EMBO J
Title: Crystal structure of the intraflagellar transport complex 25/27.
Volume: 30
Issue: 10
Pages: 1907-18
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Protein Domain
IPR034112 | RabL4_euk
Type: Family
Description: IFT27, also known as RabL4 (Rab-like4), is a small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 []. It is capable of forming a heterodimer with IFT25 (HSPB11) [, ]and is involved in the hedgehog (Hh) signaling pathway [].
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Publication
31958312 | J:302808
First Author: Zhang S
Year: 2020
Journal: Reproduction
Title: Murine germ cell-specific disruption of Ift172 causes defects in spermiogenesis and male fertility.
Volume: 159
Issue: 4
Pages: 409-421
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