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Search results 1 to 81 out of 81 for Ift81

0.044s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Intraflagellar transport of ciliary precursors such as tubulin from the cytoplasm to the ciliary tip is required for ciliogenesis []. Intraflagellar transport protein 81 (IFT81) is a component of the intraflagellar transport (IFT) complex B, which contains at least 20 different protein subunits. Together with IFT74 forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium [].
Publication
First Author: Qu W
Year: 2020
Journal: Am J Physiol Cell Physiol
Title: The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertility.
Volume: 318
Issue: 6
Pages: C1092-C1106
Protein
Organism: Mus musculus
Length: 676  
Fragment?: false
Protein
Organism: Mus musculus
Length: 64  
Fragment?: false
Protein
Organism: Mus musculus
Length: 59  
Fragment?: false
Protein
Organism: Mus musculus
Length: 244  
Fragment?: false
Protein
Organism: Mus musculus
Length: 217  
Fragment?: true
Publication
First Author: Bhogaraju S
Year: 2013
Journal: Science
Title: Molecular basis of tubulin transport within the cilium by IFT74 and IFT81.
Volume: 341
Issue: 6149
Pages: 1009-12
Protein
Organism: Mus musculus
Length: 198  
Fragment?: true
Publication
First Author: Rosenbaum JL
Year: 2002
Journal: Nat Rev Mol Cell Biol
Title: Intraflagellar transport.
Volume: 3
Issue: 11
Pages: 813-25
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Higashi M
Year: 2000
Journal: Mamm Genome
Title: Genomic organization and mapping of mouse CDV (carnitine deficiency-associated gene expressed in ventricle)-1 and its related CDV-1R gene.
Volume: 11
Issue: 12
Pages: 1053-7
Publication
First Author: Xin D
Year: 2017
Journal: Development
Title: IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
Volume: 144
Issue: 8
Pages: 1544-1553
Publication
First Author: Masuda M
Year: 1997
Journal: FEBS Lett
Title: A novel gene suppressed in the ventricle of carnitine-deficient juvenile visceral steatosis mice.
Volume: 408
Issue: 2
Pages: 221-4
Publication
First Author: Peng J
Year: 2002
Journal: Mol Biol Rep
Title: Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation.
Volume: 29
Issue: 4
Pages: 353-62
Publication
First Author: Duan S
Year: 2021
Journal: EMBO J
Title: Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
Volume: 40
Issue: 2
Pages: e105499
Publication
First Author: Hou Y
Year: 2007
Journal: J Cell Biol
Title: Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella.
Volume: 176
Issue: 5
Pages: 653-65
Publication
First Author: Howard PW
Year: 2013
Journal: Exp Cell Res
Title: Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17.
Volume: 319
Issue: 14
Pages: 2275-81
Publication
First Author: Follit JA
Year: 2009
Journal: Cell Motil Cytoskeleton
Title: Characterization of mouse IFT complex B.
Volume: 66
Issue: 8
Pages: 457-68
Publication  
First Author: Ishikawa H
Year: 2014
Journal: Elife
Title: TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.
Volume: 3
Pages: e01566
Publication
First Author: Liew GM
Year: 2014
Journal: Dev Cell
Title: The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.
Volume: 31
Issue: 3
Pages: 265-78
Publication
First Author: Lo JC
Year: 2012
Journal: PLoS Genet
Title: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
Volume: 8
Issue: 10
Pages: e1002969
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Lucker BF
Year: 2005
Journal: J Biol Chem
Title: Characterization of the intraflagellar transport complex B core: direct interaction of the IFT81 and IFT74/72 subunits.
Volume: 280
Issue: 30
Pages: 27688-96
DO Term
Protein Domain
Type: Domain
Description: This is the N-terminal domain found in IFT81 proteins. Crystal structure analysis revealed that IFT81-N adopts the fold of a calponin homology (CH) domain with structural similarity to the kinetochore complex component NDC80 with microtubule (MT)-binding properties. Functional analysis show that IFT74 and IFT81 form a tubulin-binding module required for ciliogenesis. It is suggested that IFT81-N binds the globular domain of tubulin to provide specificity, and IFT74-N recognizes the beta-tubulin tail to increase affinity [].
Protein Domain
Type: Homologous_superfamily
Description: This superfamily represents the N-terminal domain found in IFT81 (Intraflagellar transport protein 81) proteins. Crystal structure analysis revealed that IFT81-N adopts the fold of a calponin homology (CH) domain with structural similarity to the kinetochore complex component NDC80 with microtubule (MT)-binding properties. Functional analysis show that IFT74 and IFT81 form a tubulin-binding module required for ciliogenesis. It is suggested that IFT81-N binds the globular domain of tubulin to provide specificity, and IFT74-N recognizes the beta-tubulin tail to increase affinity [].
Publication
First Author: Liu H
Year: 2017
Journal: Biol Reprod
Title: IFT25, an intraflagellar transporter protein dispensable for ciliogenesis in somatic cells, is essential for sperm flagella formation.
Volume: 96
Issue: 5
Pages: 993-1006
Publication
First Author: Zhang S
Year: 2020
Journal: Reproduction
Title: Murine germ cell-specific disruption of Ift172 causes defects in spermiogenesis and male fertility.
Volume: 159
Issue: 4
Pages: 409-421
Publication
First Author: Zhang Y
Year: 2017
Journal: Dev Biol
Title: Intraflagellar transporter protein (IFT27), an IFT25 binding partner, is essential for male fertility and spermiogenesis in mice.
Volume: 432
Issue: 1
Pages: 125-139