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Search results 1 to 93 out of 93 for Ift81

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
28981 | IFT81
Type: gene
Organism: human
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Gene
100490492 | ift81
Type: gene
Organism: frog, western clawed
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Gene
373066 | Ift81
Type: gene
Organism: rat
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Gene
736358 | IFT81
Type: gene
Organism: chimpanzee
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Gene
519602 | IFT81
Type: gene
Organism: cattle
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Gene
100856715 | IFT81
Type: gene
Organism: dog, domestic
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Gene
416839 | IFT81
Type: gene
Organism: chicken
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Gene
432390 | ift81
Type: gene
Organism: zebrafish
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Gene
710434 | IFT81
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1098597 | Ift81
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029600 | IFT81
Type: Family
Description: Intraflagellar transport of ciliary precursors such as tubulin from the cytoplasm to the ciliary tip is required for ciliogenesis []. Intraflagellar transport protein 81 (IFT81) is a component of the intraflagellar transport (IFT) complex B, which contains at least 20 different protein subunits. Together with IFT74 forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium [].
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Publication
32233951 | J:292151
First Author: Qu W
Year: 2020
Journal: Am J Physiol Cell Physiol
Title: The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertility.
Volume: 318
Issue: 6
Pages: C1092-C1106
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Protein
O35594
Organism: Mus musculus/domesticus
Length: 676  
Fragment?: false
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Protein
Q3TTH0
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
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Protein
A0A0G2JGC3
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: false
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Protein
D3Z5A8
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: true
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Protein
D6RHM7
Organism: Mus musculus/domesticus
Length: 59  
Fragment?: false
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Publication
23990561 | -
First Author: Bhogaraju S
Year: 2013
Journal: Science
Title: Molecular basis of tubulin transport within the cilium by IFT74 and IFT81.
Volume: 341
Issue: 6149
Pages: 1009-12
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Protein
A0A0G2JFG8
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: true
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Publication
12415299 | -
First Author: Rosenbaum JL
Year: 2002
Journal: Nat Rev Mol Cell Biol
Title: Intraflagellar transport.
Volume: 3
Issue: 11
Pages: 813-25
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Protein Coding Gene
MGP_CAROLIEiJ_G0027709 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030019 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029955 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030030 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029747 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1098597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030483 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029867 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028870 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029231 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024289 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028707 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11130971 | J:66065
First Author: Higashi M
Year: 2000
Journal: Mamm Genome
Title: Genomic organization and mapping of mouse CDV (carnitine deficiency-associated gene expressed in ventricle)-1 and its related CDV-1R gene.
Volume: 11
Issue: 12
Pages: 1053-7
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Publication
28264835 | J:240543
First Author: Xin D
Year: 2017
Journal: Development
Title: IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
Volume: 144
Issue: 8
Pages: 1544-1553
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Publication
9187371 | J:40593
First Author: Masuda M
Year: 1997
Journal: FEBS Lett
Title: A novel gene suppressed in the ventricle of carnitine-deficient juvenile visceral steatosis mice.
Volume: 408
Issue: 2
Pages: 221-4
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Publication
12549821 | J:81850
First Author: Peng J
Year: 2002
Journal: Mol Biol Rep
Title: Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation.
Volume: 29
Issue: 4
Pages: 353-62
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Publication
33241915 | J:302201
First Author: Duan S
Year: 2021
Journal: EMBO J
Title: Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
Volume: 40
Issue: 2
Pages: e105499
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Publication
36693320 | J:333039
First Author: Zhang K
Year: 2023
Journal: Dev Cell
Title: Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis.
Volume: 58
Issue: 2
Pages: 139-154.e8
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Publication
17312020 | J:119719
First Author: Hou Y
Year: 2007
Journal: J Cell Biol
Title: Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella.
Volume: 176
Issue: 5
Pages: 653-65
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Publication
23810713 | J:203626
First Author: Howard PW
Year: 2013
Journal: Exp Cell Res
Title: Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17.
Volume: 319
Issue: 14
Pages: 2275-81
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Publication
19253336 | J:154656
First Author: Follit JA
Year: 2009
Journal: Cell Motil Cytoskeleton
Title: Characterization of mouse IFT complex B.
Volume: 66
Issue: 8
Pages: 457-68
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Publication
24596149 | J:215956
 
First Author: Ishikawa H
Year: 2014
Journal: Elife
Title: TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.
Volume: 3
Pages: e01566
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Publication
25443296 | J:217382
First Author: Liew GM
Year: 2014
Journal: Dev Cell
Title: The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.
Volume: 31
Issue: 3
Pages: 265-78
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Publication
26980730 | J:234200
First Author: Katoh Y
Year: 2016
Journal: J Biol Chem
Title: Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex.
Volume: 291
Issue: 21
Pages: 10962-75
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Publication
29038301 | J:255486
First Author: Agbu SO
Year: 2018
Journal: J Cell Biol
Title: The small GTPase RSG1 controls a final step in primary cilia initiation.
Volume: 217
Issue: 1
Pages: 413-427
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Publication
23055941 | J:193640
First Author: Lo JC
Year: 2012
Journal: PLoS Genet
Title: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
Volume: 8
Issue: 10
Pages: e1002969
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
15955805 | -
First Author: Lucker BF
Year: 2005
Journal: J Biol Chem
Title: Characterization of the intraflagellar transport complex B core: direct interaction of the IFT81 and IFT74/72 subunits.
Volume: 280
Issue: 30
Pages: 27688-96
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DO Term
DOID:0080295 | short-rib thoracic dysplasia 19 with or without polydactyly
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Protein Domain
IPR041146 | IFT81_CH
Type: Domain
Description: This is the N-terminal domain found in IFT81 proteins. Crystal structure analysis revealed that IFT81-N adopts the fold of a calponin homology (CH) domain with structural similarity to the kinetochore complex component NDC80 with microtubule (MT)-binding properties. Functional analysis show that IFT74 and IFT81 form a tubulin-binding module required for ciliogenesis. It is suggested that IFT81-N binds the globular domain of tubulin to provide specificity, and IFT74-N recognizes the beta-tubulin tail to increase affinity [].
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Protein Domain
IPR043016 | IFT81_N_sf
Type: Homologous_superfamily
Description: This superfamily represents the N-terminal domain found in IFT81 (Intraflagellar transport protein 81) proteins. Crystal structure analysis revealed that IFT81-N adopts the fold of a calponin homology (CH) domain with structural similarity to the kinetochore complex component NDC80 with microtubule (MT)-binding properties. Functional analysis show that IFT74 and IFT81 form a tubulin-binding module required for ciliogenesis. It is suggested that IFT81-N binds the globular domain of tubulin to provide specificity, and IFT74-N recognizes the beta-tubulin tail to increase affinity [].
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Publication
28430876 | J:245566
First Author: Liu H
Year: 2017
Journal: Biol Reprod
Title: IFT25, an intraflagellar transporter protein dispensable for ciliogenesis in somatic cells, is essential for sperm flagella formation.
Volume: 96
Issue: 5
Pages: 993-1006
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Publication
31958312 | J:302808
First Author: Zhang S
Year: 2020
Journal: Reproduction
Title: Murine germ cell-specific disruption of Ift172 causes defects in spermiogenesis and male fertility.
Volume: 159
Issue: 4
Pages: 409-421
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Publication
28964737 | J:251964
First Author: Zhang Y
Year: 2017
Journal: Dev Biol
Title: Intraflagellar transporter protein (IFT27), an IFT25 binding partner, is essential for male fertility and spermiogenesis in mice.
Volume: 432
Issue: 1
Pages: 125-139
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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