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Search results 1 to 100 out of 438 for Ift88

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
8100 | IFT88
Type: gene
Organism: human
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Gene
514177 | IFT88
Type: gene
Organism: cattle
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Gene
418952 | IFT88
Type: gene
Organism: chicken
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Gene
321855 | ift88
Type: gene
Organism: zebrafish
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Gene
703874 | IFT88
Type: gene
Organism: macaque, rhesus
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Gene
100490149 | ift88
Type: gene
Organism: frog, western clawed
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Gene
305918 | Ift88
Type: gene
Organism: rat
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Gene
477345 | IFT88
Type: gene
Organism: dog, domestic
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Gene
452461 | IFT88
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:98715 | Ift88
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:1314968
Assay Type: Immunohistochemistry
Annotation Date: 2021-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1787127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6718503
Age: postnatal day 0
Image: 5D Ift88 cKO
Note: Reduced expression compared with the control.
Specimen Label: 5D Ift88 cKO
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:7380630
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380676
Age: embryonic day 10.5
Note: Expression in neuroepithelial cilia.
Specimen Label: 5C IFT88 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7380630
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380676
Age: embryonic day 10.5
Note: Expression in neuroepithelial cilia.
Specimen Label: 5C IFT88 bromi
Detected: true
Specimen Num: 2
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Publication
34045314 | J:329276
First Author: Hu C
Year: 2021
Journal: J Am Soc Nephrol
Title: Sex-Dependent Effects of Nephron Ift88 Disruption on BP, Renal Function, and Cystogenesis.
Volume: 32
Issue: 9
Pages: 2210-2222
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Publication
24594320 | J:210639
First Author: Mitchell EH
Year: 2014
Journal: Cilia
Title: Normal mammary development and function in mice with Ift88 deleted in MMTV- and K14-Cre expressing cells.
Volume: 3
Issue: 1
Pages: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7380630
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380676
Age: embryonic day 10.5
Note: Expression in neuroepithelial cilia.
Specimen Label: 5D IFT88 WT (lower right)
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7380630
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380676
Age: embryonic day 10.5
Note: Expression in neuroepithelial cilia.
Specimen Label: 5D IFT88 bromi (lower right)
Detected: true
Specimen Num: 4
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Publication
35274831 | J:328673
First Author: Hu C
Year: 2022
Journal: Physiol Rep
Title: Profiling renal sodium transporters in mice with nephron Ift88 disruption: Association with sex, cysts, and blood pressure.
Volume: 10
Issue: 5
Pages: e15206
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Publication
11062270 | J:65500
First Author: Pazour GJ
Year: 2000
Journal: J Cell Biol
Title: Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella.
Volume: 151
Issue: 3
Pages: 709-18
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Publication
34927449 | J:330925
First Author: Hu C
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: Multiomic identification of factors associated with progression to cystic kidney disease in mice with nephron Ift88 disruption.
Volume: 322
Issue: 2
Pages: F175-F192
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Publication
30791390 | J:282458
 
First Author: Wang Y
Year: 2019
Journal: J Dev Biol
Title: Distinct Activities of Gli1 and Gli2 in the Absence of Ift88 and the Primary Cilia.
Volume: 7
Issue: 1
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Publication
21337470 | J:169055
First Author: Kierszenbaum AL
Year: 2011
Journal: Dev Dyn
Title: GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail.
Volume: 240
Issue: 3
Pages: 723-36
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Publication
18629867 | J:138332
First Author: Johnson ET
Year: 2008
Journal: Dev Dyn
Title: Role for primary cilia in the regulation of mouse ovarian function.
Volume: 237
Issue: 8
Pages: 2053-60
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Publication
29500191 | J:261446
First Author: Vion AC
Year: 2018
Journal: J Cell Biol
Title: Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression.
Volume: 217
Issue: 5
Pages: 1651-1665
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Publication
18366137 | J:138088
First Author: Lehman JM
Year: 2008
Journal: Dev Dyn
Title: The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men.
Volume: 237
Issue: 8
Pages: 1960-71
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Publication
33602982 | J:303741
First Author: Lee J
Year: 2021
Journal: Sci Rep
Title: Loss of primary cilia promotes mitochondria-dependent apoptosis in thyroid cancer.
Volume: 11
Issue: 1
Pages: 4181
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Publication
25184295 | J:221536
First Author: Berbari NF
Year: 2014
Journal: PLoS One
Title: Hippocampal and cortical primary cilia are required for aversive memory in mice.
Volume: 9
Issue: 9
Pages: e106576
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Publication
35475783 | J:324461
   
First Author: Xiao H
Year: 2022
Journal: Elife
Title: Mechanical stimulation promotes enthesis injury repair by mobilizing Prrx1+ cells via ciliary TGF-β signaling.
Volume: 11
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Publication
25904703 | J:226958
First Author: Sas KM
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage.
Volume: 309
Issue: 1
Pages: F79-87
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Publication
33021968 | J:299977
 
First Author: Sun JS
Year: 2021
Journal: J Clin Invest
Title: Ventromedial hypothalamic primary cilia control energy and skeletal homeostasis.
Volume: 131
Issue: 1
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Publication
22941275 | J:193432
First Author: McIntyre JC
Year: 2012
Journal: Nat Med
Title: Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model.
Volume: 18
Issue: 9
Pages: 1423-8
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Publication
24213915 | J:210906
First Author: Gilley SK
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Deletion of airway cilia results in noninflammatory bronchiectasis and hyperreactive airways.
Volume: 306
Issue: 2
Pages: L162-9
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Publication
21493775 | J:226746
First Author: Bell PD
Year: 2011
Journal: J Am Soc Nephrol
Title: Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis.
Volume: 22
Issue: 5
Pages: 839-48
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Publication
21112568 | J:168485
First Author: Beckervordersandforth R
Year: 2010
Journal: Cell Stem Cell
Title: In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells.
Volume: 7
Issue: 6
Pages: 744-58
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Publication
25825494 | J:226962
First Author: Jiang L
Year: 2015
Journal: J Biol Chem
Title: Heterotrimeric kinesin-2 (KIF3) mediates transition zone and axoneme formation of mouse photoreceptors.
Volume: 290
Issue: 20
Pages: 12765-78
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Publication
21285373 | J:169219
First Author: Blitzer AL
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium.
Volume: 108
Issue: 7
Pages: 2819-24
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Publication
36505420 | J:336988
 
First Author: Nava A
Year: 2022
Journal: Front Immunol
Title: Mice with lung airway ciliopathy develop persistent Mycobacterium abscessus lung infection and have a proinflammatory lung phenotype associated with decreased T regulatory cells.
Volume: 13
Pages: 1017540
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Publication
18084282 | J:132369
First Author: Corbit KC
Year: 2008
Journal: Nat Cell Biol
Title: Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms.
Volume: 10
Issue: 1
Pages: 70-6
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Publication
32308017 | J:294815
First Author: Yoo M
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Integrin-β1 is required for the renal cystogenesis caused by ciliary defects.
Volume: 318
Issue: 5
Pages: F1306-F1312
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Publication
35926636 | J:327291
 
First Author: Yang DJ
Year: 2022
Journal: Metabolism
Title: Primary cilia regulate adaptive responses to fasting.
Volume: 135
Pages: 155273
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Publication
31934864 | J:286088
   
First Author: Bowie E
Year: 2020
Journal: Elife
Title: TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons.
Volume: 9
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Publication
24899059 | J:214249
First Author: Beck Gooz M
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.
Volume: 307
Issue: 5
Pages: F551-9
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Publication
23599282 | J:197356
First Author: Berbari NF
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice.
Volume: 110
Issue: 19
Pages: 7796-801
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Publication
23124988 | J:346470
First Author: Berbari NF
Year: 2013
Journal: Cytoskeleton (Hoboken)
Title: Microtubule modifications and stability are altered by cilia perturbation and in cystic kidney disease.
Volume: 70
Issue: 1
Pages: 24-31
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Publication
26446227 | J:226461
First Author: Joiner AM
Year: 2015
Journal: J Neurosci
Title: Primary Cilia on Horizontal Basal Cells Regulate Regeneration of the Olfactory Epithelium.
Volume: 35
Issue: 40
Pages: 13761-72
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Publication
30061191 | J:265307
First Author: Green WW
Year: 2018
Journal: J Neurosci
Title: Peripheral Gene Therapeutic Rescue of an Olfactory Ciliopathy Restores Sensory Input, Axonal Pathfinding, and Odor-Guided Behavior.
Volume: 38
Issue: 34
Pages: 7462-7475
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Publication
31337691 | J:346381
First Author: Zimmerman KA
Year: 2019
Journal: J Am Soc Nephrol
Title: Tissue-Resident Macrophages Promote Renal Cystic Disease.
Volume: 30
Issue: 10
Pages: 1841-1856
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Publication
33188191 | J:301300
First Author: Lee CH
Year: 2020
Journal: Nat Commun
Title: Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamus.
Volume: 11
Issue: 1
Pages: 5772
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Publication
37858465 | J:342124
First Author: Hoi KK
Year: 2023
Journal: Cell Rep
Title: Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling.
Volume: 42
Issue: 10
Pages: 113272
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Publication
19654211 | J:153142
First Author: Clement CA
Year: 2009
Journal: J Cell Sci
Title: The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation.
Volume: 122
Issue: Pt 17
Pages: 3070-82
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Publication
26926121 | J:232339
First Author: Guo DF
Year: 2016
Journal: PLoS Genet
Title: The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane.
Volume: 12
Issue: 2
Pages: e1005890
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Publication
19701205 | J:154128
First Author: Wong SY
Year: 2009
Journal: Nat Med
Title: Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis.
Volume: 15
Issue: 9
Pages: 1055-61
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Publication
33728725 | J:328710
First Author: Rockwell DM
Year: 2022
Journal: Dev Dyn
Title: A transgenic Alx4-CreER mouse to analyze anterior limb and nephric duct development.
Volume: 251
Issue: 9
Pages: 1524-1534
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Publication
25999403 | J:229242
 
First Author: Saigusa T
Year: 2015
Journal: Physiol Rep
Title: Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease.
Volume: 3
Issue: 5
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Publication
32698004 | J:306169
First Author: Peralta M
Year: 2020
Journal: Cell Rep
Title: Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis.
Volume: 32
Issue: 3
Pages: 107932
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Publication
23386061 | J:207807
First Author: Kodani A
Year: 2013
Journal: EMBO J
Title: Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.
Volume: 32
Issue: 4
Pages: 597-607
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Publication
38038747 | J:344445
First Author: Ma Y
Year: 2023
Journal: Cell Mol Life Sci
Title: CCDC146 is required for sperm flagellum biogenesis and male fertility in mice.
Volume: 81
Issue: 1
Pages: 1
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Publication
35671424 | J:336975
First Author: Li W
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Primary cilia in satellite cells are the mechanical sensors for muscle hypertrophy.
Volume: 119
Issue: 24
Pages: e2103615119
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Publication
25564561 | J:225786
First Author: Waters AM
Year: 2015
Journal: J Med Genet
Title: The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes.
Volume: 52
Issue: 3
Pages: 147-56
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Publication
31845891 | J:291752
   
First Author: Portal C
Year: 2019
Journal: Elife
Title: Primary cilia deficiency in neural crest cells models anterior segment dysgenesis in mouse.
Volume: 8
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Publication
12821668 | J:86875
First Author: Baker SA
Year: 2003
Journal: J Biol Chem
Title: IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia.
Volume: 278
Issue: 36
Pages: 34211-8
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Publication
22228099 | J:181886
First Author: Zhang Q
Year: 2012
Journal: Hum Mol Genet
Title: BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes.
Volume: 21
Issue: 9
Pages: 1945-53
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Publication
21653639 | J:175371
First Author: Friedland-Little JM
Year: 2011
Journal: Hum Mol Genet
Title: A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus.
Volume: 20
Issue: 19
Pages: 3725-37
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Publication
30289203 | J:308860
First Author: Burns TA
Year: 2019
Journal: Anat Rec (Hoboken)
Title: A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.
Volume: 302
Issue: 1
Pages: 136-145
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Publication
28346501 | J:241357
First Author: Schock EN
Year: 2017
Journal: PLoS One
Title: A tissue-specific role for intraflagellar transport genes during craniofacial development.
Volume: 12
Issue: 3
Pages: e0174206
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Publication
19596798 | J:153289
First Author: Zhu D
Year: 2009
Journal: J Cell Sci
Title: Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes.
Volume: 122
Issue: Pt 15
Pages: 2760-8
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Publication
27727273 | J:236236
First Author: Hong CJ
Year: 2016
Journal: PLoS Genet
Title: Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.
Volume: 12
Issue: 10
Pages: e1006357
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Publication
17166921 | J:117033
First Author: Haycraft CJ
Year: 2007
Journal: Development
Title: Intraflagellar transport is essential for endochondral bone formation.
Volume: 134
Issue: 2
Pages: 307-16
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Publication
24469809 | J:206657
First Author: Ye X
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.
Volume: 111
Issue: 6
Pages: 2164-9
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Publication
19253336 | J:154656
First Author: Follit JA
Year: 2009
Journal: Cell Motil Cytoskeleton
Title: Characterization of mouse IFT complex B.
Volume: 66
Issue: 8
Pages: 457-68
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Publication
28556366 | J:243646
First Author: Toomer KA
Year: 2017
Journal: Dev Dyn
Title: A role for primary cilia in aortic valve development and disease.
Volume: 246
Issue: 8
Pages: 625-634
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Publication
21429982 | J:171221
First Author: Croyle MJ
Year: 2011
Journal: Development
Title: Role of epidermal primary cilia in the homeostasis of skin and hair follicles.
Volume: 138
Issue: 9
Pages: 1675-85
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Publication
28069795 | J:241596
First Author: Tian H
Year: 2017
Journal: Hum Mol Genet
Title: Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate.
Volume: 26
Issue: 5
Pages: 860-872
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Publication
17804638 | J:145113
First Author: Chizhikov VV
Year: 2007
Journal: J Neurosci
Title: Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool.
Volume: 27
Issue: 36
Pages: 9780-9
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Publication
28954202 | J:255606
First Author: Cela P
Year: 2018
Journal: J Dent Res
Title: Ciliopathy Protein Tmem107 Plays Multiple Roles in Craniofacial Development.
Volume: 97
Issue: 1
Pages: 108-117
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Publication
28115485 | J:239604
First Author: Okamoto S
Year: 2017
Journal: J Neurosci
Title: Ick Ciliary Kinase Is Essential for Planar Cell Polarity Formation in Inner Ear Hair Cells and Hearing Function.
Volume: 37
Issue: 8
Pages: 2073-2085
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Publication
31301300 | J:282363
First Author: Tessier S
Year: 2019
Journal: Dev Biol
Title: NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis.
Volume: 455
Issue: 2
Pages: 369-381
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Publication
26825015 | J:229895
 
First Author: Sugiyama Y
Year: 2016
Journal: Mech Dev
Title: Non-essential role for cilia in coordinating precise alignment of lens fibres.
Volume: 139
Pages: 10-7
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Publication
19036983 | J:142500
First Author: Willaredt MA
Year: 2008
Journal: J Neurosci
Title: A crucial role for primary cilia in cortical morphogenesis.
Volume: 28
Issue: 48
Pages: 12887-900
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Publication
25114218 | J:213914
First Author: Tong CK
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Primary cilia are required in a unique subpopulation of neural progenitors.
Volume: 111
Issue: 34
Pages: 12438-43
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Publication
26542012 | J:228881
First Author: Gazea M
Year: 2016
Journal: Dev Biol
Title: Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain.
Volume: 409
Issue: 1
Pages: 55-71
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Publication
15930098 | J:98800
First Author: Liu A
Year: 2005
Journal: Development
Title: Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors.
Volume: 132
Issue: 13
Pages: 3103-11
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Protein Coding Gene
MGP_CAROLIEiJ_G0019349 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021406 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021342 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021370 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_98715 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021809 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020667 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021116 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0021312 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0021246 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0021833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0020410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0020719 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0030367 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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