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Search results 1 to 100 out of 1734 for Igf1

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
3479 | IGF1
Type: gene
Organism: human
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Gene
610255 | IGF1
Type: gene
Organism: dog, domestic
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Gene
418090 | IGF1
Type: gene
Organism: chicken
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Gene
114433 | igf1
Type: gene
Organism: zebrafish
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Gene
698444 | IGF1
Type: gene
Organism: macaque, rhesus
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Gene
100486334 | igf1
Type: gene
Organism: frog, western clawed
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Gene
281239 | IGF1
Type: gene
Organism: cattle
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Gene
443318 | IGF1
Type: gene
Organism: sheep
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Gene
key_19506 | IGF1
Type: gene
Organism: pig, domestic
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Gene
key_33649 | IGF1
Type: gene
Organism: horse
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Gene
24482 | Igf1
Type: gene
Organism: rat
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Gene
741055 | IGF1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:96432 | Igf1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:5296874
Assay Type: RT-PCR
Annotation Date: 2011-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5296889
Age: embryonic day 7.5
Image: 1
Specimen Label: Igf1 +
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5296874
Assay Type: RT-PCR
Annotation Date: 2011-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5296889
Age: embryonic day 7.5
Image: 1
Specimen Label: Igf1 -
Detected: true
Specimen Num: 2
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Publication
10385438 | J:56188
First Author: Wang J
Year: 1999
Journal: Endocrinology
Title: Effects of Igf1 gene deletion on postnatal growth patterns.
Volume: 140
Issue: 7
Pages: 3391-4
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Publication
18827067 | J:142809
First Author: Svensson J
Year: 2008
Journal: J Endocrinol
Title: Liver-derived IGF1 enhances the androgenic response in prostate.
Volume: 199
Issue: 3
Pages: 489-97
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Publication
28402847 | J:251122
First Author: Spadaro O
Year: 2017
Journal: Cell Rep
Title: IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge.
Volume: 19
Issue: 2
Pages: 225-234
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Publication
8813730 | J:33843
First Author: Baker J
Year: 1996
Journal: Mol Endocrinol
Title: Effects of an Igf1 gene null mutation on mouse reproduction.
Volume: 10
Issue: 7
Pages: 903-18
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Publication
20685873 | J:165676
First Author: Kawai M
Year: 2010
Journal: Endocrinology
Title: Nocturnin suppresses igf1 expression in bone by targeting the 3' untranslated region of igf1 mRNA.
Volume: 151
Issue: 10
Pages: 4861-70
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Publication
19033454 | J:142247
First Author: Stratikopoulos E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The hormonal action of IGF1 in postnatal mouse growth.
Volume: 105
Issue: 49
Pages: 19378-83
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Publication
10544181 | J:58350
First Author: Wang J
Year: 1999
Journal: FASEB J
Title: Igf1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy.
Volume: 13
Issue: 14
Pages: 1985-90
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Publication
7525909 | J:20461
First Author: Thomas GA
Year: 1994
Journal: J Pathol
Title: Site of production of IGF1 in the normal and stimulated mouse thyroid.
Volume: 173
Issue: 4
Pages: 355-60
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Publication
26958833 | J:229663
First Author: Mardinly AR
Year: 2016
Journal: Nature
Title: Sensory experience regulates cortical inhibition by inducing IGF1 in VIP neurons.
Volume: 531
Issue: 7594
Pages: 371-5
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Publication
24109593 | J:211911
First Author: Santhanam M
Year: 2013
Journal: Mol Endocrinol
Title: Hepatic-specific accessibility of Igf1 gene enhancers is independent of growth hormone signaling.
Volume: 27
Issue: 12
Pages: 2080-92
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Publication
32439763 | J:290858
 
First Author: Marchant C
Year: 2020
Journal: Development
Title: Vessel-derived angiocrine IGF1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis.
Volume: 147
Issue: 11
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Publication
33848471 | J:315961
First Author: Young K
Year: 2021
Journal: Cell Stem Cell
Title: Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging.
Volume: 28
Issue: 8
Pages: 1473-1482.e7
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GXD Expression
GXD Expression
     
Probe: MGI:6175305
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190591
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Igf1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6175305
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190591
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Igf1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6175305
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190591
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Igf1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6175305
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190591
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Igf1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6175305
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190591
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Igf1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6175305
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190591
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Igf1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6175305
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190591
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Igf1
Detected: true
Specimen Num: 7
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Publication
25837582 | J:225466
First Author: Van Landeghem L
Year: 2015
Journal: FASEB J
Title: IGF1 stimulates crypt expansion via differential activation of 2 intestinal stem cell populations.
Volume: 29
Issue: 7
Pages: 2828-42
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Publication
28533420 | J:271936
First Author: Hennebry A
Year: 2017
Journal: J Endocrinol
Title: IGF1 stimulates greater muscle hypertrophy in the absence of myostatin in male mice.
Volume: 234
Issue: 2
Pages: 187-200
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Publication
37338990 | J:339974
 
First Author: Miyagawa K
Year: 2023
Journal: JCI Insight
Title: Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to pagetic lesion formation.
Volume: 8
Issue: 14
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Publication
23404854 | J:231264
First Author: Villani RM
Year: 2013
Journal: Endocr Relat Cancer
Title: Murine basal cell carcinoma leads to tumor-mediated alterations in endocrine Igf1 signaling.
Volume: 20
Issue: 3
Pages: 273-81
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Publication
8742817 | J:31787
First Author: Klein S
Year: 1996
Journal: J Hered
Title: Genetic and physical mapping of the chicken IGF1 gene to chromosome 1 and conservation of synteny with other vertebrate genomes.
Volume: 87
Issue: 1
Pages: 10-4
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Publication
36214448 | J:330322
   
First Author: Gao F
Year: 2022
Journal: Elife
Title: Decoding the IGF1 signaling gene regulatory network behind alveologenesis from a mouse model of bronchopulmonary dysplasia.
Volume: 11
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Publication
25790853 | J:220467
First Author: Galvis LA
Year: 2015
Journal: Development
Title: Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung.
Volume: 142
Issue: 8
Pages: 1458-69
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Publication
24034272 | J:202024
First Author: Charalambous M
Year: 2014
Journal: Acta Physiol (Oxf)
Title: Perturbations to the IGF1 growth pathway and adult energy homeostasis following disruption of mouse chromosome 12 imprinting.
Volume: 210
Issue: 1
Pages: 174-87
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Publication
19627267 | J:216124
First Author: Yuan R
Year: 2009
Journal: Aging Cell
Title: Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels.
Volume: 8
Issue: 3
Pages: 277-87
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Publication
19920132 | J:159955
First Author: Hewitt SC
Year: 2010
Journal: J Biol Chem
Title: Estrogen-mediated regulation of Igf1 transcription and uterine growth involves direct binding of estrogen receptor alpha to estrogen-responsive elements.
Volume: 285
Issue: 4
Pages: 2676-85
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Publication
28500773 | J:329354
First Author: Chen L
Year: 2017
Journal: FEBS J
Title: The energy sensing LKB1-AMPKα1 pathway regulates IGF1 secretion and consequent activation of the IGF1R-PKB pathway in primary hepatocytes.
Volume: 284
Issue: 13
Pages: 2096-2109
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Publication
22566614 | J:184775
First Author: Yuan R
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains.
Volume: 109
Issue: 21
Pages: 8224-9
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Publication
26341476 | J:273070
First Author: Rodríguez-de la Rosa L
Year: 2015
Journal: Hear Res
Title: Comparative gene expression study of the vestibular organ of the Igf1 deficient mouse using whole-transcript arrays.
Volume: 330
Issue: Pt A
Pages: 62-77
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Publication
24958851 | J:212180
First Author: Mellios N
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome.
Volume: 111
Issue: 27
Pages: 9947-52
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Publication
22563064 | J:185132
First Author: Touvron M
Year: 2012
Journal: Dis Model Mech
Title: Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction.
Volume: 5
Issue: 4
Pages: 481-91
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Publication
7718235 | J:24953
First Author: Beck KD
Year: 1995
Journal: Neuron
Title: Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons.
Volume: 14
Issue: 4
Pages: 717-30
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Publication
17376816 | J:125847
First Author: Sperandeo MP
Year: 2007
Journal: Am J Physiol Cell Physiol
Title: Slc7a7 disruption causes fetal growth retardation by downregulating Igf1 in the mouse model of lysinuric protein intolerance.
Volume: 293
Issue: 1
Pages: C191-8
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QTL
MGI:6111723 | Igfdq2
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:6111722 | Igfdq1
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:6111725 | Igfdq3
Type: QTL
Organism: mouse, laboratory
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Publication
27307439 | J:234284
First Author: Chen L
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion.
Volume: 113
Issue: 26
Pages: 7219-24
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Publication
23031221 | J:244417
 
First Author: Suto J
Year: 2012
Journal: BMC Res Notes
Title: Quantitative trait locus mapping of genes that control body length and plasma insulin-like growth factor 1 level in mice.
Volume: 5
Pages: 547
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Publication
30981207 | J:290289
First Author: Anisimov VN
Year: 2019
Journal: Aging (Albany NY)
Title: In mice transgenic for IGF1 under keratin-14 promoter, lifespan is decreased and the rates of aging and thymus involution are accelerated.
Volume: 11
Issue: 7
Pages: 2098-2110
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Publication
29783855 | J:265953
First Author: Zheng Y
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Intestinal epithelial cell-specific IGF1 promotes the expansion of intestinal stem cells during epithelial regeneration and functions on the intestinal immune homeostasis.
Volume: 315
Issue: 4
Pages: E638-E649
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Publication
18451161 | J:134610
First Author: Anzo M
Year: 2008
Journal: Cancer Res
Title: Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression.
Volume: 68
Issue: 9
Pages: 3342-9
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Publication
31073032 | J:280809
First Author: Hewitt SC
Year: 2019
Journal: J Biol Chem
Title: A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Igf1 (insulin-like growth factor 1).
Volume: 294
Issue: 25
Pages: 9746-9759
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Publication
9135074 | J:39752
First Author: Bol DK
Year: 1997
Journal: Oncogene
Title: Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice.
Volume: 14
Issue: 14
Pages: 1725-34
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Publication
9989803 | J:65037
First Author: Su HY
Year: 1999
Journal: J Invest Dermatol
Title: Increased vibrissa growth in transgenic mice expressing insulin-like growth factor 1.
Volume: 112
Issue: 2
Pages: 245-8
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Publication
11994404 | J:76405
First Author: George M
Year: 2002
Journal: J Clin Invest
Title: Beta cell expression of IGF-I leads to recovery from type 1 diabetes.
Volume: 109
Issue: 9
Pages: 1153-63
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Publication
17525368 | J:137808
First Author: Santini MP
Year: 2007
Journal: Circ Res
Title: Enhancing repair of the mammalian heart.
Volume: 100
Issue: 12
Pages: 1732-40
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Publication
16709615 | J:129478
First Author: Liao L
Year: 2006
Journal: Endocrinology
Title: Liver-specific overexpression of the insulin-like growth factor-I enhances somatic growth and partially prevents the effects of growth hormone deficiency.
Volume: 147
Issue: 8
Pages: 3877-88
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Publication
7744859 | J:25522
First Author: Coleman ME
Year: 1995
Journal: J Biol Chem
Title: Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice.
Volume: 270
Issue: 20
Pages: 12109-16
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Publication
10544175 | J:58354
First Author: Delaughter MC
Year: 1999
Journal: FASEB J
Title: Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice.
Volume: 13
Issue: 14
Pages: 1923-9
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Publication
11867450 | J:135463
First Author: Wang ZM
Year: 2002
Journal: Biophys J
Title: Sustained overexpression of IGF-1 prevents age-dependent decrease in charge movement and intracellular Ca(2+) in mouse skeletal muscle.
Volume: 82
Issue: 3
Pages: 1338-44
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Publication
8710922 | J:35215
First Author: Reiss K
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice.
Volume: 93
Issue: 16
Pages: 8630-5
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Publication
20678571 | J:164592
First Author: Zhang B
Year: 2010
Journal: Free Radic Biol Med
Title: Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3beta, and PTEN.
Volume: 49
Issue: 7
Pages: 1238-53
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Publication
17130467 | J:121004
First Author: Casellas A
Year: 2006
Journal: Diabetes
Title: Expression of IGF-I in pancreatic islets prevents lymphocytic infiltration and protects mice from type 1 diabetes.
Volume: 55
Issue: 12
Pages: 3246-55
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Publication
10205143 | J:54842
First Author: Leri A
Year: 1999
Journal: Circ Res
Title: Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice.
Volume: 84
Issue: 7
Pages: 752-62
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Publication
11934830 | J:128671
First Author: Welch S
Year: 2002
Journal: Circ Res
Title: Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice.
Volume: 90
Issue: 6
Pages: 641-8
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Allele
Tg(Myh6-IGF1)34Pia | MGI:3630343
Name: transgene insertion 34, Piero Anversa
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
37725888 | J:340813
 
First Author: Wang P
Year: 2023
Journal: Redox Biol
Title: Accumulation of endogenous adenosine improves cardiomyocyte metabolism via epigenetic reprogramming in an ischemia-reperfusion model.
Volume: 67
Pages: 102884
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Publication
18212051 | J:134212
First Author: Liao L
Year: 2008
Journal: Mol Cell Biol
Title: Steroid receptor coactivator 3 maintains circulating insulin-like growth factor I (IGF-I) by controlling IGF-binding protein 3 expression.
Volume: 28
Issue: 7
Pages: 2460-9
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Publication
17211878 | J:125041
First Author: Cochrane RL
Year: 2007
Journal: Genesis
Title: Rearrangement of a conditional allele regardless of inheritance of a Cre recombinase transgene.
Volume: 45
Issue: 1
Pages: 17-20
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Publication
12815703 | J:104820
First Author: Cheng CM
Year: 2003
Journal: J Neurosci Res
Title: Insulin-like growth factor 1 is essential for normal dendritic growth.
Volume: 73
Issue: 1
Pages: 1-9
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Publication
10377413 | J:69517
First Author: Yakar S
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Normal growth and development in the absence of hepatic insulin-like growth factor I.
Volume: 96
Issue: 13
Pages: 7324-9
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Publication
10077676 | J:53580
First Author: Adesanya OO
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Insulin-like growth factor 1 is required for G2 progression in the estradiol-induced mitotic cycle.
Volume: 96
Issue: 6
Pages: 3287-91
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Publication
37354902 | J:341100
First Author: Roethler O
Year: 2023
Journal: Neuron
Title: Single genomic enhancers drive experience-dependent GABAergic plasticity to maintain sensory processing in the adult cortex.
Volume: 111
Issue: 17
Pages: 2693-2708.e8
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Publication
25252870 | J:220215
First Author: Steger J
Year: 2015
Journal: Leukemia
Title: Insulin-like growth factor 1 is a direct HOXA9 target important for hematopoietic transformation.
Volume: 29
Issue: 4
Pages: 901-8
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Publication
31323135 | J:291095
First Author: Barton ER
Year: 2019
Journal: Muscle Nerve
Title: Functional muscle hypertrophy by increased insulin-like growth factor 1 does not require dysferlin.
Volume: 60
Issue: 4
Pages: 464-473
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Publication
25017732 | J:220137
First Author: Blutke A
Year: 2014
Journal: Mol Cell Endocrinol
Title: Genetic dissection of IGF1-dependent and -independent effects of permanent GH excess on postnatal growth and organ pathology of mice.
Volume: 394
Issue: 1-2
Pages: 88-98
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Publication
34363749 | J:314272
First Author: Zaman R
Year: 2021
Journal: Immunity
Title: Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress.
Volume: 54
Issue: 9
Pages: 2057-2071.e6
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Publication
12215457 | J:80190
First Author: Zhang M
Year: 2002
Journal: J Biol Chem
Title: Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization.
Volume: 277
Issue: 46
Pages: 44005-12
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Publication
25742797 | J:238880
First Author: Kostallari E
Year: 2015
Journal: Development
Title: Pericytes in the myovascular niche promote post-natal myofiber growth and satellite cell quiescence.
Volume: 142
Issue: 7
Pages: 1242-53
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Publication
23960076 | J:207248
First Author: Ma W
Year: 2013
Journal: J Biol Chem
Title: An androgen receptor-microrna-29a regulatory circuitry in mouse epididymis.
Volume: 288
Issue: 41
Pages: 29369-81
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Publication
16901968 | J:117180
First Author: Loladze AV
Year: 2006
Journal: Endocrinology
Title: Epithelial-specific and stage-specific functions of insulin-like growth factor-I during postnatal mammary development.
Volume: 147
Issue: 11
Pages: 5412-23
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Publication
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