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Search results 1 to 100 out of 720 for Igf1r

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: López IP
Year: 2015
Journal: Transgenic Res
Title: Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC-CreERT2; Igf1r fl/fl double transgenic mice.
Volume: 24
Issue: 2
Pages: 279-94
Publication
First Author: Rota LM
Year: 2014
Journal: Cancer Res
Title: IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumors.
Volume: 74
Issue: 19
Pages: 5668-79
Publication
First Author: Xu F
Year: 2018
Journal: J Cell Biol
Title: KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth.
Volume: 217
Issue: 10
Pages: 3480-3496
Publication
First Author: Zumsteg A
Year: 2012
Journal: Mol Cancer Res
Title: Repression of malignant tumor progression upon pharmacologic IGF1R blockade in a mouse model of insulinoma.
Volume: 10
Issue: 6
Pages: 800-9
Publication  
First Author: Jakubik M
Year: 2014
Journal: Neurosci Lett
Title: Heterozygous Igf1r deletion does not ameliorate pathological features associated with polyglutamine-containing huntingtin fragment.
Volume: 580
Pages: 52-5
Publication
First Author: Piñeiro-Hermida S
Year: 2017
Journal: Sci Rep
Title: IGF1R deficiency attenuates acute inflammatory response in a bleomycin-induced lung injury mouse model.
Volume: 7
Issue: 1
Pages: 4290
Publication
First Author: Triplett TA
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.
Volume: 113
Issue: 8
Pages: E1016-25
Publication
First Author: Klinakis A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Igf1r as a therapeutic target in a mouse model of basal-like breast cancer.
Volume: 106
Issue: 7
Pages: 2359-64
Publication
First Author: López IP
Year: 2016
Journal: PLoS One
Title: Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.
Volume: 11
Issue: 11
Pages: e0166388
Publication
First Author: Bedzhov I
Year: 2012
Journal: PLoS Genet
Title: Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin.
Volume: 8
Issue: 3
Pages: e1002609
Publication
First Author: Baumgarten SC
Year: 2017
Journal: Endocrinology
Title: IGF1R Expression in Ovarian Granulosa Cells Is Essential for Steroidogenesis, Follicle Survival, and Fertility in Female Mice.
Volume: 158
Issue: 7
Pages: 2309-2318
Publication
First Author: Ludwig T
Year: 1996
Journal: Dev Biol
Title: Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.
Volume: 177
Issue: 2
Pages: 517-35
Publication
First Author: Annenkov A
Year: 2011
Journal: Biochim Biophys Acta
Title: A chimeric receptor of the insulin-like growth factor receptor type 1 (IGFR1) and a single chain antibody specific to myelin oligodendrocyte glycoprotein activates the IGF1R signalling cascade in CG4 oligodendrocyte progenitors.
Volume: 1813
Issue: 8
Pages: 1428-37
Publication
First Author: Linnerth NM
Year: 2009
Journal: Neoplasia
Title: Type I insulin-like growth factor receptor induces pulmonary tumorigenesis.
Volume: 11
Issue: 7
Pages: 672-82
Publication
First Author: Xuan S
Year: 2002
Journal: J Clin Invest
Title: Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor.
Volume: 110
Issue: 7
Pages: 1011-9
Publication
First Author: Jones RA
Year: 2014
Journal: PLoS One
Title: IGF-IR mediated mammary tumorigenesis is enhanced during pubertal development.
Volume: 9
Issue: 9
Pages: e108781
Publication
First Author: Jones RA
Year: 2007
Journal: Oncogene
Title: Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation.
Volume: 26
Issue: 11
Pages: 1636-44
Publication
First Author: Thakur S
Year: 2017
Journal: Biochem Biophys Res Commun
Title: IGF-1 receptor haploinsufficiency leads to age-dependent development of metabolic syndrome.
Volume: 486
Issue: 4
Pages: 937-944
Publication
First Author: Mason JL
Year: 2003
Journal: J Neurosci
Title: Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination.
Volume: 23
Issue: 20
Pages: 7710-8
Publication
First Author: Sundaresan S
Year: 1989
Journal: Somat Cell Mol Genet
Title: Insulin-like growth factor I receptor gene is concordant with c-Fes protooncogene and mouse chromosome 7 in somatic cell hybrids.
Volume: 15
Issue: 4
Pages: 373-6
Publication
First Author: Evdokimova V
Year: 2012
Journal: Sci Signal
Title: IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors.
Volume: 5
Issue: 255
Pages: ra92
Publication
First Author: Shi Y
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation.
Volume: 112
Issue: 15
Pages: 4678-83
Publication
First Author: Jenkins CR
Year: 2012
Journal: Exp Hematol
Title: IGF signaling contributes to malignant transformation of hematopoietic progenitors by the MLL-AF9 oncoprotein.
Volume: 40
Issue: 9
Pages: 715-723.e6
Publication
First Author: Kulkarni RN
Year: 2002
Journal: Nat Genet
Title: beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.
Volume: 31
Issue: 1
Pages: 111-5
Publication
First Author: Wu S
Year: 2015
Journal: Endocrinology
Title: Insulin-Like Growth Factor-Independent Effects of Growth Hormone on Growth Plate Chondrogenesis and Longitudinal Bone Growth.
Volume: 156
Issue: 7
Pages: 2541-51
Publication
First Author: Sell C
Year: 1994
Journal: Mol Cell Biol
Title: Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts.
Volume: 14
Issue: 6
Pages: 3604-12
Publication
First Author: Liu X
Year: 1998
Journal: Cancer Res
Title: Inhibition of insulin-like growth factor I receptor expression in neuroblastoma cells induces the regression of established tumors in mice.
Volume: 58
Issue: 23
Pages: 5432-8
Publication
First Author: O'Neill BT
Year: 2015
Journal: Cell Rep
Title: Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis.
Volume: 11
Issue: 8
Pages: 1220-35
Publication
First Author: Boucher J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.
Volume: 111
Issue: 40
Pages: 14512-7
Publication
First Author: Boucher J
Year: 2010
Journal: Sci Signal
Title: A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis.
Volume: 3
Issue: 151
Pages: ra87
Publication
First Author: Biggs BT
Year: 2016
Journal: PLoS One
Title: Insulin-Like Growth Factors Are Expressed in the Taste System, but Do Not Maintain Adult Taste Buds.
Volume: 11
Issue: 2
Pages: e0148315
Publication
First Author: Liu JP
Year: 1993
Journal: Cell
Title: Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r).
Volume: 75
Issue: 1
Pages: 59-72
Publication
First Author: Spadaro O
Year: 2017
Journal: Cell Rep
Title: IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge.
Volume: 19
Issue: 2
Pages: 225-234
Publication
First Author: Spadaro O
Year: 2016
Journal: Cell Rep
Title: Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence.
Volume: 14
Issue: 7
Pages: 1571-1580
Publication
First Author: Piñeiro-Hermida S
Year: 2017
Journal: Allergy
Title: Attenuated airway hyperresponsiveness and mucus secretion in HDM-exposed Igf1r-deficient mice.
Volume: 72
Issue: 9
Pages: 1317-1326
Publication
First Author: Piñeiro-Hermida S
Year: 2017
Journal: PLoS One
Title: Characterization of the acute inflammatory profile and resolution of airway inflammation after Igf1r-gene targeting in a murine model of HDM-induced asthma.
Volume: 12
Issue: 12
Pages: e0190159
Publication
First Author: Zeger M
Year: 2007
Journal: Glia
Title: Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination.
Volume: 55
Issue: 4
Pages: 400-11
Publication
First Author: Bareja A
Year: 2017
Journal: Biochem J
Title: HASF (C3orf58) is a novel ligand of the insulin-like growth factor 1 receptor.
Volume: 474
Issue: 5
Pages: 771-780
Publication
First Author: Baker J
Year: 1993
Journal: Cell
Title: Role of insulin-like growth factors in embryonic and postnatal growth.
Volume: 75
Issue: 1
Pages: 73-82
Publication
First Author: Boucher J
Year: 2016
Journal: Diabetes
Title: Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function.
Volume: 65
Issue: 8
Pages: 2201-13
Publication
First Author: Neirijnck Y
Year: 2018
Journal: FASEB J
Title: Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells.
Volume: 32
Issue: 6
Pages: 3321-3335
Publication
First Author: Laustsen PG
Year: 2007
Journal: Mol Cell Biol
Title: Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function.
Volume: 27
Issue: 5
Pages: 1649-64
Publication
First Author: Santoro MA
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon.
Volume: 309
Issue: 7
Pages: G578-89
Publication
First Author: Ikeda H
Year: 2009
Journal: J Mol Cell Cardiol
Title: Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy.
Volume: 47
Issue: 5
Pages: 664-75
Publication
First Author: Yuldasheva NY
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Haploinsufficiency of the insulin-like growth factor-1 receptor enhances endothelial repair and favorably modifies angiogenic progenitor cell phenotype.
Volume: 34
Issue: 9
Pages: 2051-8
Publication
First Author: Engberding N
Year: 2009
Journal: Arterioscler Thromb Vasc Biol
Title: Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells.
Volume: 29
Issue: 3
Pages: 408-15
Publication  
First Author: Morcavallo A
Year: 2014
Journal: Matrix Biol
Title: Decorin differentially modulates the activity of insulin receptor isoform A ligands.
Volume: 35
Pages: 82-90
Publication
First Author: Withers DJ
Year: 1999
Journal: Nat Genet
Title: Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.
Volume: 23
Issue: 1
Pages: 32-40
Publication
First Author: Herron BJ
Year: 2002
Journal: Nat Genet
Title: Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.
Volume: 30
Issue: 2
Pages: 185-9
Publication
First Author: Yang M
Year: 2015
Journal: Development
Title: Lin28 promotes the proliferative capacity of neural progenitor cells in brain development.
Volume: 142
Issue: 9
Pages: 1616-27
Publication
First Author: Xian L
Year: 2012
Journal: Nat Med
Title: Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells.
Volume: 18
Issue: 7
Pages: 1095-101
Publication
First Author: Wang Y
Year: 2011
Journal: J Bone Miner Res
Title: IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway.
Volume: 26
Issue: 7
Pages: 1437-46
Publication
First Author: Higashi Y
Year: 2016
Journal: Circulation
Title: Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice.
Volume: 133
Issue: 23
Pages: 2263-78
Publication
First Author: Lehtinen MK
Year: 2011
Journal: Neuron
Title: The cerebrospinal fluid provides a proliferative niche for neural progenitor cells.
Volume: 69
Issue: 5
Pages: 893-905
Publication
First Author: Pehar M
Year: 2010
Journal: Aging Cell
Title: Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death.
Volume: 9
Issue: 2
Pages: 174-90
Publication
First Author: Xuan S
Year: 2010
Journal: J Biol Chem
Title: Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.
Volume: 285
Issue: 52
Pages: 41044-50
Publication
First Author: O'Neill BT
Year: 2016
Journal: J Clin Invest
Title: Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis.
Volume: 126
Issue: 9
Pages: 3433-46
Publication
First Author: Wang K
Year: 2019
Journal: BMC Dev Biol
Title: Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development.
Volume: 19
Issue: 1
Pages: 5
Publication
First Author: Osorio FG
Year: 2016
Journal: Nat Med
Title: Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.
Volume: 22
Issue: 1
Pages: 91-6
Publication
First Author: Louvi A
Year: 1997
Journal: Dev Biol
Title: Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.
Volume: 189
Issue: 1
Pages: 33-48
Publication
First Author: Kido Y
Year: 2002
Journal: J Biol Chem
Title: Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance.
Volume: 277
Issue: 39
Pages: 36740-7
Publication
First Author: van Kleffens M
Year: 1998
Journal: Mol Cell Endocrinol
Title: mRNA expression patterns of the IGF system during mouse limb bud development, determined by whole mount in situ hybridization.
Volume: 138
Issue: 1-2
Pages: 151-61
Publication
First Author: Guha M
Year: 2010
Journal: Biochim Biophys Acta
Title: Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets.
Volume: 1797
Issue: 6-7
Pages: 1055-65
Publication
First Author: Moran JL
Year: 2006
Journal: Genome Res
Title: Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse.
Volume: 16
Issue: 3
Pages: 436-40
Publication
First Author: Jin J
Year: 2019
Journal: PLoS One
Title: Igf1R/InsR function is required for axon extension and corpus callosum formation.
Volume: 14
Issue: 7
Pages: e0219362
Publication
First Author: Nef S
Year: 2003
Journal: Nature
Title: Testis determination requires insulin receptor family function in mice.
Volume: 426
Issue: 6964
Pages: 291-5
Publication
First Author: Li P
Year: 2011
Journal: Development
Title: IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.
Volume: 138
Issue: 9
Pages: 1795-805
Publication
First Author: Okano T
Year: 2011
Journal: J Neurosci
Title: Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea.
Volume: 31
Issue: 49
Pages: 18104-18
Publication
First Author: Fujita K
Year: 2013
Journal: Int J Dev Biol
Title: Molecular signaling at the fusion stage of the mouse mandibular arch: involvement of insulin-like growth factor family.
Volume: 57
Issue: 5
Pages: 399-406
Publication
First Author: Pais RS
Year: 2013
Journal: PLoS One
Title: Transcriptome analysis in prenatal IGF1-deficient mice identifies molecular pathways and target genes involved in distal lung differentiation.
Volume: 8
Issue: 12
Pages: e83028
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Wada J
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Cloning of cDNA for the alpha subunit of mouse insulin-like growth factor I receptor and the role of the receptor in metanephric development.
Volume: 90
Issue: 21
Pages: 10360-4
Publication
First Author: Dinchuk JE
Year: 2010
Journal: Endocrinology
Title: Insulin receptor (IR) pathway hyperactivity in IGF-IR null cells and suppression of downstream growth signaling using the dual IGF-IR/IR inhibitor, BMS-754807.
Volume: 151
Issue: 9
Pages: 4123-32
Publication
First Author: Holzenberger M
Year: 2000
Journal: Nucleic Acids Res
Title: Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene.
Volume: 28
Issue: 21
Pages: E92
Publication
First Author: Holzenberger M
Year: 2000
Journal: Endocrinology
Title: A targeted partial invalidation of the insulin-like growth factor I receptor gene in mice causes a postnatal growth deficit.
Volume: 141
Issue: 7
Pages: 2557-66
Publication
First Author: Kappeler L
Year: 2008
Journal: PLoS Biol
Title: Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism.
Volume: 6
Issue: 10
Pages: e254
Publication
First Author: Desbois-Mouthon C
Year: 2006
Journal: FASEB J
Title: Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout.
Volume: 20
Issue: 6
Pages: 773-5