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Search results 1 to 100 out of 2606 for Igf2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: sheep
Gene
Type: gene
Organism: horse
Gene
Type: gene
Organism: pig, domestic
Gene
Type: gene
Organism: wallaby, tammar
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: The insulin family of proteins groups together several evolutionarily related active peptides []: these include insulin [, ], relaxin [, ], insect prothoracicotropic hormone (bombyxin) [], insulin-like growth factors (IGF1 and IGF2) [, ], mammalian Leydig cell-specific insulin-like peptide (gene INSL3), early placenta insulin-like peptide (ELIP) (gene INSL4), locust insulin-related peptide (LIRP), molluscan insulin-related peptides (MIP), and Caenorhabditis elegans insulin-like peptides. The 3D structures of a number of family members have been determined [, , ]. The fold comprises two polypeptide chains (A and B) linked by two disulphide bonds: all share a conserved arrangement of 4 cysteines in their A chain, the first of which is linked by a disulphide bond to the third, while the second and fourth are linked by interchain disulphide bonds to cysteines in the B chain. The IGFs, or somatomedins, play a key role in pre-adolescent mammalian growth. IGF2 appears to be induced by placental lactogen and is thought to play a role in foetal development [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Davies K
Year: 2002
Journal: Development
Title: Disruption of mesodermal enhancers for Igf2 in the minute mutant.
Volume: 129
Issue: 7
Pages: 1657-68
Gene
Type: gene
Organism: human
GXD Expression  
Probe: MGI:1333147
Assay Type: RNA in situ
Annotation Date: 1999-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:1333503
Age: embryonic day 9.5
Image: Igf2 Control
Specimen Label: Igf2 Control
Detected: true
Specimen Num: 1
Publication
First Author: Cattanach BM
Year: 2000
Journal: Hum Mol Genet
Title: Two imprinted gene mutations: three phenotypes.
Volume: 9
Issue: 15
Pages: 2263-73
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is strong, scattered staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is strong, scattered staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is strong, scattered staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is strong, scattered staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is strong, scattered staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is strong, scattered staining the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4450870
Age: embryonic day 11.5
Image: Igf2 - E11.5
Note: There is strong, scattered staining in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Label: Igf2 - E11.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is strong, scattered staining in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450870
Age: embryonic day 11.5
Image: Igf2 - E11.5
Note: There is very strong staining in the VZ of the AVH & strong, scattered staining in the dorsal thalamus, the prethalamus, dorsal & ventral POAs, the PVH, VMH & ARH nuclei, the anterior & posterior IDs, the premam, mam & supramam zones & the TT.
Specimen Label: Igf2 - E11.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is very strong staining in the ventricular zone of the AVH and strong, scattered staining in the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the DAH and the PH.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is strong, scattered staining in the ventricular zone of the cerebral cortex.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is strong, scattered staining in the ventricular zone of the cerebral cortex.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is strong, scattered staining in the ventricular zone of the cerebral cortex.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is strong, scattered staining in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is strong, scattered staining in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4450870
Age: embryonic day 11.5
Image: Igf2 - E11.5
Note: There is strong, scattered staining in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Label: Igf2 - E11.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is strong, scattered staining in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is strong, scattered staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is strong, scattered staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is strong, scattered staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is strong, scattered staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is strong, scattered staining in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is strong, scattered staining in the mantle zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is strong, scattered staining in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is strong, scattered staining in the mantle zone of the premam, mam and supramam zones.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is very strong staining in the ventricular zone of the AVH and strong, scattered staining in the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and anterior and posterior IDs.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is very strong staining in the ventricular zone of the AVH and strong, scattered staining in the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and anterior and posterior IDs.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Scattered
Stage: TS19
Assay Id: MGI:4450870
Age: embryonic day 11.5
Image: Igf2 - E11.5
Note: There is strong, scattered staining in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Specimen Label: Igf2 - E11.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is strong, scattered staining in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is strong, scattered staining in the ventricular zone of the premam, mam and supramam zones.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4450870
Age: embryonic day 14.5
Image: Igf2 - E14.5
Note: There is strong, scattered staining in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Igf2 - E14.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is strong, scattered staining in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Scattered
Stage: TS20
Assay Id: MGI:4450870
Age: embryonic day 12.5
Image: Igf2 - E12.5
Note: There is strong, scattered staining in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Igf2 - E12.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4442718
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Scattered
Stage: TS24
Assay Id: MGI:4450870
Age: embryonic day 16.5
Image: Igf2 - E16.5
Note: There is strong, scattered staining in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Igf2 - E16.5
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3724421
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826225
Age: embryonic day 14.5
Image: Additional file 4 Igf2
Specimen Label: Additional file 4 Igf2
Detected: true
Specimen Num: 1
Publication
First Author: Peters J
Year: 2004
Journal: Brief Funct Genomic Proteomic
Title: Identification and characterisation of imprinted genes in the mouse.
Volume: 2
Issue: 4
Pages: 320-33
Publication
First Author: Eden S
Year: 2001
Journal: EMBO J
Title: An upstream repressor element plays a role in Igf2 imprinting.
Volume: 20
Issue: 13
Pages: 3518-25
Publication
First Author: Dull TJ
Year: 1984
Journal: Nature
Title: Insulin-like growth factor II precursor gene organization in relation to insulin gene family.
Volume: 310
Issue: 5980
Pages: 777-81
Protein
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: true
Publication
First Author: Leighton PA
Year: 1995
Journal: Genes Dev
Title: An enhancer deletion affects both H19 and Igf2 expression.
Volume: 9
Issue: 17
Pages: 2079-89
Protein
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: false
Publication
First Author: Blundell TL
Year: 1980
Journal: Nature
Title: Hormone families: pancreatic hormones and homologous growth factors.
Volume: 287
Issue: 5785
Pages: 781-7
Publication
First Author: Bell GI
Year: 1979
Journal: Nature
Title: Nucleotide sequence of a cDNA clone encoding human preproinsulin.
Volume: 282
Issue: 5738
Pages: 525-7
Publication
First Author: Bell GI
Year: 1980
Journal: Nature
Title: Sequence of the human insulin gene.
Volume: 284
Issue: 5751
Pages: 26-32
Publication
First Author: Cooke RM
Year: 1991
Journal: Biochemistry
Title: Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study.
Volume: 30
Issue: 22
Pages: 5484-91
Publication
First Author: Brange J
Year: 1997
Journal: Proteins
Title: A model of insulin fibrils derived from the x-ray crystal structure of a monomeric insulin (despentapeptide insulin).
Volume: 27
Issue: 4
Pages: 507-16
Publication
First Author: Garibay-Tupas JL
Year: 1999
Journal: J Mol Endocrinol
Title: Analysis of the 5'-upstream regions of the human relaxin H1 and H2 genes and their chromosomal localization on chromosome 9p24.1 by radiation hybrid and breakpoint mapping.
Volume: 23
Issue: 3
Pages: 355-65
Publication
First Author: Gunnersen JM
Year: 1996
Journal: Mol Cell Endocrinol
Title: Expression of human relaxin genes: characterization of a novel alternatively-spliced human relaxin mRNA species.
Volume: 118
Issue: 1-2
Pages: 85-94
Publication
First Author: Kondo H
Year: 1996
Journal: J Mol Biol
Title: Multiple gene copies for bombyxin, an insulin-related peptide of the silkmoth Bombyx mori: structural signs for gene rearrangement and duplication responsible for generation of multiple molecular forms of bombyxin.
Volume: 259
Issue: 5
Pages: 926-37
Publication
First Author: Sato A
Year: 1992
Journal: J Biochem
Title: 1H-NMR assignment and secondary structure of human insulin-like growth factor-I (IGF-I) in solution.
Volume: 111
Issue: 4
Pages: 529-36
Publication
First Author: Liao J
Year: 2021
Journal: Cell Rep
Title: Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes.
Volume: 34
Issue: 6
Pages: 108729
Publication
First Author: Sakatani T
Year: 2005
Journal: Science
Title: Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice.
Volume: 307
Issue: 5717
Pages: 1976-8
Publication
First Author: Nakao K
Year: 2009
Journal: Biochem Biophys Res Commun
Title: IGF2 modulates the microenvironment for osteoclastogenesis.
Volume: 378
Issue: 3
Pages: 462-6
Publication
First Author: Ekström TJ
Year: 1994
Journal: Horm Res
Title: Parental imprinting and the IGF2 gene.
Volume: 42
Issue: 4-5
Pages: 176-81
GXD Expression    
Probe: MGI:2177638
Assay Type: Northern blot
Annotation Date: 2002-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2177649
Age: embryonic day 15.5
Image: 4
Specimen Label: Igf2 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2177638
Assay Type: Northern blot
Annotation Date: 2002-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755028
Stage: TS28
Assay Id: MGI:2177649
Age: postnatal adult
Image: 4
Specimen Label: Igf2 2
Detected: true
Specimen Num: 2
Publication
First Author: Hammerle CM
Year: 2020
Journal: PLoS Genet
Title: Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function.
Volume: 16
Issue: 10
Pages: e1009069
Publication
First Author: Park KS
Year: 2017
Journal: Nucleic Acids Res
Title: Loss of imprinting mutations define both distinct and overlapping roles for misexpression of IGF2 and of H19 lncRNA.
Volume: 45
Issue: 22
Pages: 12766-12779
Gene
Type: gene
Organism: chimpanzee
Heritable Phenotypic Marker
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
Publication  
First Author: Duart-Garcia C
Year: 2014
Journal: Int J Genomics
Title: Functional expression study of igf2 antisense transcript in mouse.
Volume: 2014
Pages: 390296
Publication
First Author: Sun FL
Year: 1997
Journal: Nature
Title: Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome.
Volume: 389
Issue: 6653
Pages: 809-15
Publication
First Author: Weber M
Year: 2003
Journal: Mol Cell Biol
Title: Genomic imprinting controls matrix attachment regions in the Igf2 gene.
Volume: 23
Issue: 24
Pages: 8953-9
Publication
First Author: Killian JK
Year: 2001
Journal: J Exp Zool
Title: Monotreme IGF2 expression and ancestral origin of genomic imprinting.
Volume: 291
Issue: 2
Pages: 205-12
Publication
First Author: Alzhanov D
Year: 2016
Journal: Physiol Genomics
Title: Characterizing a distal muscle enhancer in the mouse Igf2 locus.
Volume: 48
Issue: 2
Pages: 167-72
Publication
First Author: Haley VL
Year: 2012
Journal: EMBO Mol Med
Title: Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes.
Volume: 4
Issue: 8
Pages: 705-18
Publication
First Author: Modi H
Year: 2015
Journal: Diabetes
Title: Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function.
Volume: 64
Issue: 12
Pages: 4148-57
Publication  
First Author: Zhang Q
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Overexpression of IGF2 affects mouse weight and glycolipid metabolism and IGF2 is positively related to macrosomia.
Volume: 14
Pages: 1030453
GXD Expression    
Probe: MGI:1267017
Assay Type: RT-PCR
Annotation Date: 2015-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:5691926
Age: embryonic day 10.0
Image: 8
Specimen Label: Igf2 N +
Detected: true
Specimen Num: 3
Publication
First Author: Harper J
Year: 2006
Journal: Cancer Res
Title: Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting.
Volume: 66
Issue: 4
Pages: 1940-8
Publication
First Author: Jones BK
Year: 2001
Journal: Hum Mol Genet
Title: Deletion of a nuclease-sensitive region between the Igf2 and H19 genes leads to Igf2 misregulation and increased adiposity.
Volume: 10
Issue: 8
Pages: 807-14
Publication
First Author: Murrell A
Year: 2001
Journal: EMBO Rep
Title: An intragenic methylated region in the imprinted Igf2 gene augments transcription.
Volume: 2
Issue: 12
Pages: 1101-6
Publication
First Author: Sferruzzi-Perri AN
Year: 2011
Journal: Endocrinology
Title: Placental-specific Igf2 deficiency alters developmental adaptations to undernutrition in mice.
Volume: 152
Issue: 8
Pages: 3202-12
Publication
First Author: Pant V
Year: 2004
Journal: Mol Cell Biol
Title: Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance.
Volume: 24
Issue: 8
Pages: 3497-504
Publication  
First Author: Dikkes P
Year: 2007
Journal: Brain Res
Title: IGF2 knockout mice are resistant to kainic acid-induced seizures and neurodegeneration.
Volume: 1175
Pages: 85-95
Publication
First Author: Webber AL
Year: 1998
Journal: Nature
Title: Location of enhancers is essential for the imprinting of H19 and Igf2 genes.
Volume: 391
Issue: 6668
Pages: 711-5
Publication
First Author: Fertan E
Year: 2023
Journal: Sci Rep
Title: Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1-42 in Alzheimer's disease.
Volume: 13
Issue: 1
Pages: 2043
Publication
First Author: Jones BK
Year: 1998
Journal: Genes Dev
Title: Igf2 imprinting does not require its own DNA methylation or H19 RNA.
Volume: 12
Issue: 14
Pages: 2200-7
Publication
First Author: Schmidt JV
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Enhancer competition between H19 and Igf2 does not mediate their imprinting.
Volume: 96
Issue: 17
Pages: 9733-8
Publication
First Author: Feil R
Year: 1994
Journal: Development
Title: Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes.
Volume: 120
Issue: 10
Pages: 2933-43
Publication
First Author: Rostam Zadehl J
Year: 2005
Journal: Genetika
Title: TGFalpha reactivates imprinted Igf2 in the parthenogenetic mice embryos and placenta.
Volume: 41
Issue: 10
Pages: 1387-91
Publication
First Author: Sandovici I
Year: 2021
Journal: Sci Rep
Title: Autocrine IGF2 programmes β-cell plasticity under conditions of increased metabolic demand.
Volume: 11
Issue: 1
Pages: 7717