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Search results 1 to 100 out of 1563 for Ihh

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Type Details Score
Gene
3549 | IHH
Type: gene
Organism: human
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Gene
522714 | IHH
Type: gene
Organism: cattle
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Gene
395801 | IHH
Type: gene
Organism: chicken
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Gene
704046 | IHH
Type: gene
Organism: macaque, rhesus
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Gene
100145111 | ihh
Type: gene
Organism: frog, western clawed
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Gene
84399 | Ihh
Type: gene
Organism: rat
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Gene
488533 | IHH
Type: gene
Organism: dog, domestic
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Gene
470652 | IHH
Type: gene
Organism: chimpanzee
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Protein Domain
IPR033385 | IHH
Type: Family
Description: Indian hedgehog protein (IHH, MEROPS identifier C46.003) is important for the development and growth of bone and cartilage in the embryo []. IHH is synthesized as a precursor and activates itself by cleavage of Gly-Cys bond, in which the thiol group of the cysteine is the nucleophile []. This results in the release of the N-terminal effector domain, and no further proteolytic activity takes place. The differentiation of chondrocytes in embryonic mouse limbs, induction of the expression of nodal in the lateral plate mesoderm of early chick embryos, and affinities for hedgehog-binding proteins have been compared for Sonic, Indian and Desert hedgehog proteins [].
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Protein Coding Gene
MGI:96533 | Ihh
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
9079674 | J:39298
First Author: Valentini RP
Year: 1997
Journal: J Biol Chem
Title: Post-translational processing and renal expression of mouse Indian hedgehog.
Volume: 272
Issue: 13
Pages: 8466-73
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Publication
8662546 | J:76742
First Author: Vortkamp A
Year: 1996
Journal: Science
Title: Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein.
Volume: 273
Issue: 5275
Pages: 613-22
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Protein
P97812
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
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GXD Expression
GXD Expression
Probe: MGI:5447304
Assay Type: RNA in situ
Annotation Date: 2013-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5447314
Age: embryonic day 14.5
Image: 1C ihh
Note: Expression restricted to mature and early hypertrophic chondrocytes.
Specimen Label: 1C ihh
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5447304
Assay Type: RNA in situ
Annotation Date: 2013-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5447314
Age: postnatal week 10
Image: 2D ihh
Note: Expression restricted to mature and early hypertrophic chondrocytes of the growth plate.
Specimen Label: 2D ihh
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5447304
Assay Type: RNA in situ
Annotation Date: 2013-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5447314
Age: embryonic day 12.0
Image: 1A ihh
Specimen Label: 1A ihh
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5447304
Assay Type: RNA in situ
Annotation Date: 2013-01-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3262326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5447314
Age: embryonic day 18.0
Image: 2A ihh
Note: Expression restricted to mature and early hypertrophic chondrocytes.
Specimen Label: 2A ihh
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5447304
Assay Type: RNA in situ
Annotation Date: 2013-01-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1914228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5447314
Age: postnatal week 10
Image: 2D ihh
Note: Very low levels of expression detected in secondary ossification center.
Specimen Label: 2D ihh
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:2158649
Assay Type: RNA in situ
Annotation Date: 2002-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1815522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:2178838
Age: embryonic day 14.5
Image: 5 Ihh E14.5 Cre10;Smo
Note: Expression was present in prehypertrophic chondrocytes similar to wild type.
Specimen Label: 5 Ihh E14.5 Cre10;Smo
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3043194
Assay Type: RNA in situ
Annotation Date: 2004-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3043265
Age: embryonic day 18.5
Image: 8 -/- tibia Ihh
Note: Expression was detected in prehypertrophic and hypertrophic chondrocytes but was weak in terminal hypertrophic chondrocytes.
Specimen Label: 8 -/- tibia Ihh
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3043194
Assay Type: RNA in situ
Annotation Date: 2004-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1914326
Stage: TS26
Assay Id: MGI:3043265
Age: embryonic day 18.5
Image: 8 -/- femur Ihh
Specimen Label: 8 -/- femur Ihh
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1742821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5446498
Age: embryonic day 13.5
Image: 4 Ihh 13.5 spdh/spdh
Specimen Label: 4 Ihh 13.5 spdh/spdh
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5446498
Age: embryonic day 14.5
Image: 4 Ihh 14.5 wt
Specimen Label: 4 Ihh 14.5 wt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5446498
Age: embryonic day 14.5
Image: 4 Ihh 14.5 spdh/spdh
Note: Expression domains partially fused with each other.
Specimen Label: 4 Ihh 14.5 spdh/spdh
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5446498
Age: embryonic day 16.5
Image: 4 Ihh 16.5 wt
Specimen Label: 4 Ihh 16.5 wt
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1742824
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5446498
Age: embryonic day 16.5
Image: 4 Ihh 16.5 spdh/spdh
Note: Expression was completely absent, except for digit 1 and distal phalanges that were somewhat spared.
Specimen Label: 4 Ihh 16.5 spdh/spdh
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3539127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5446498
Age: postnatal newborn
Image: 4 Ihh Newborn wt
Specimen Label: 4 Ihh Newborn wt
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:2158649
Assay Type: RNA in situ
Annotation Date: 2002-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1815522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:2178838
Age: embryonic day 14.5
Image: 5 Ihh E14.5 WT
Note: Expression was present in prehypertrophic chondrocytes.
Specimen Label: 5 Ihh E14.5 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:2158649
Assay Type: RNA in situ
Annotation Date: 2002-05-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1815522
Stage: TS22
Assay Id: MGI:2178838
Age: embryonic day 14.5
Image: 5 Ihh E14.5 Ihh
Specimen Label: 5 Ihh E14.5 Ihh
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3263921
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5446498
Age: embryonic day 13.5
Image: 4 Ihh 13.5 wt
Note: Expression in pre-hypertrophic chondrocytes and also in digital anlagen. Expression at three sites in each phalangeal anlagen.
Specimen Label: 4 Ihh 13.5 wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3539227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5446498
Age: postnatal newborn
Image: 4 Ihh Newborn spdh/spdh
Note: Expression at sides of bones in ectopic areas of ossification.
Specimen Label: 4 Ihh Newborn spdh/spdh
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:2158649
Assay Type: RNA in situ
Annotation Date: 2002-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:2178838
Age: embryonic day 18.5
Image: 5 Ihh E18.5 WT
Specimen Label: 5 Ihh E18.5 WT
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3043194
Assay Type: RNA in situ
Annotation Date: 2004-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3043265
Age: embryonic day 18.5
Image: 8 +/+ tibia Ihh
Note: Expression was detected in prehypertrophic and hypertrophic chondrocytes but was weak in terminal hypertrophic chondrocytes.
Specimen Label: 8 +/+ tibia Ihh
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:2158649
Assay Type: RNA in situ
Annotation Date: 2002-05-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1914226
Stage: TS26
Assay Id: MGI:2178838
Age: embryonic day 18.5
Image: 5 Ihh E18.5 Ihh
Specimen Label: 5 Ihh E18.5 Ihh
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:2158649
Assay Type: RNA in situ
Annotation Date: 2002-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:2178838
Age: embryonic day 18.5
Image: 5 Ihh E18.5 Cre10;Smo
Note: Expression was maintained along the longitudinal axis of the tibia similar to the wild type.
Specimen Label: 5 Ihh E18.5 Cre10;Smo
Detected: true
Specimen Num: 5
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Publication
11472839 | -
First Author: Pathi S
Year: 2001
Journal: Mech Dev
Title: Comparative biological responses to human Sonic, Indian, and Desert hedgehog.
Volume: 106
Issue: 1-2
Pages: 107-17
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Protein
Q80XI9
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
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Publication
16905129 | J:119575
First Author: Long F
Year: 2006
Journal: Dev Biol
Title: Independent regulation of skeletal growth by Ihh and IGF signaling.
Volume: 298
Issue: 1
Pages: 327-33
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Publication
21297010 | J:171003
First Author: Sugito H
Year: 2011
Journal: J Dent Res
Title: Ihh signaling regulates mandibular symphysis development and growth.
Volume: 90
Issue: 5
Pages: 625-31
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Publication
16284117 | J:102948
First Author: Koziel L
Year: 2005
Journal: Development
Title: Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation.
Volume: 132
Issue: 23
Pages: 5249-60
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Publication
29985470 | J:269974
First Author: Li S
Year: 2018
Journal: Sci Rep
Title: Knockdown Indian Hedgehog (Ihh) does not delay Fibular Fracture Healing in genetic deleted Ihh mice and pharmaceutical inhibited Ihh Mice.
Volume: 8
Issue: 1
Pages: 10351
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Publication
24149372 | J:207785
 
First Author: Piao J
Year: 2013
Journal: Sci Rep
Title: Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling.
Volume: 3
Pages: 3022
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GXD Expression
GXD Expression
 
Probe: MGI:7310473
Assay Type: RNA in situ
Annotation Date: 2022-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7310480
Age: embryonic day 15.5
Note: Expression patterns not markedly affected compared with wild type.
Specimen Label: 1d -/- Ihh
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2006-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3687194
Age: embryonic day 16.5
Note: Expression was in the core of the humerus and lining the bone collar.
Specimen Label: 7 Ihh top
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3687193
Assay Type: RNA in situ
Annotation Date: 2006-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3687194
Age: embryonic day 16.5
Note: Expression was in the core of the humerus and lining the bone collar at close to wild type levels.
Specimen Label: 7 Ihh bottom
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6459909
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6459913
Age: embryonic day 15.5
Note: Most expression localized to prehypertrophic zone.
Specimen Label: 2C IHH WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6459909
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-06
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1910623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6459913
Age: embryonic day 15.5
Note: Substantially reduced expression in prehypertrophic zone.
Specimen Label: 2C IHH Mutant
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7310473
Assay Type: RNA in situ
Annotation Date: 2022-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7310480
Age: embryonic day 15.5
Note: Expression in prehypertrophic zone
Specimen Label: 1d +/+ Ihh
Detected: true
Specimen Num: 2
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Publication
15177029 | J:92212
First Author: Koziel L
Year: 2004
Journal: Dev Cell
Title: Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification.
Volume: 6
Issue: 6
Pages: 801-13
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Publication
29447948 | J:265448
 
First Author: Kurio N
Year: 2018
Journal: Matrix Biol
Title: Roles of Ihh signaling in chondroprogenitor function in postnatal condylar cartilage.
Volume: 67
Pages: 15-31
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Publication
21167467 | J:169421
First Author: Klopocki E
Year: 2011
Journal: Am J Hum Genet
Title: Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis.
Volume: 88
Issue: 1
Pages: 70-5
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Publication
19906842 | J:154906
First Author: Wang W
Year: 2009
Journal: Development
Title: Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription.
Volume: 136
Issue: 24
Pages: 4143-53
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Publication
23383321 | J:198327
First Author: Kim EJ
Year: 2013
Journal: PLoS One
Title: Ihh and Runx2/Runx3 signaling interact to coordinate early chondrogenesis: a mouse model.
Volume: 8
Issue: 2
Pages: e55296
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Publication
14973297 | J:88635
First Author: Long F
Year: 2004
Journal: Development
Title: Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton.
Volume: 131
Issue: 6
Pages: 1309-18
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Publication
29771958 | J:262487
First Author: Murgai A
Year: 2018
Journal: PLoS One
Title: Cooperation of BMP and IHH signaling in interdigital cell fate determination.
Volume: 13
Issue: 5
Pages: e0197535
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Publication
16818445 | J:119030
First Author: Später D
Year: 2006
Journal: Development
Title: Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis.
Volume: 133
Issue: 15
Pages: 3039-49
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Publication
11984876 | J:76397
First Author: Wang WF
Year: 2002
Journal: Dev Dyn
Title: Growth defect in Grg5 null mice is associated with reduced Ihh signaling in growth plates.
Volume: 224
Issue: 1
Pages: 79-89
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Publication
19948490 | J:155396
First Author: Bellon E
Year: 2009
Journal: J Cell Biol
Title: delta-EF1 is a negative regulator of Ihh in the developing growth plate.
Volume: 187
Issue: 5
Pages: 685-99
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Publication
31382618 | J:290125
 
First Author: Yang H
Year: 2019
Journal: Int J Mol Sci
Title: Inhibition of Ihh Reverses Temporomandibular Joint Osteoarthritis via a PTH1R Signaling Dependent Mechanism.
Volume: 20
Issue: 15
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Publication
19252479 | J:147878
First Author: Gao B
Year: 2009
Journal: Nature
Title: A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range.
Volume: 458
Issue: 7242
Pages: 1196-200
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Publication
28846100 | J:260073
First Author: Will AJ
Year: 2017
Journal: Nat Genet
Title: Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog).
Volume: 49
Issue: 10
Pages: 1539-1545
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Publication
27930311 | J:239074
First Author: Cai H
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling.
Volume: 113
Issue: 51
Pages: 14751-14756
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Publication
29311969 | J:309718
 
First Author: Veistinen LK
Year: 2017
Journal: Front Physiol
Title: Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets.
Volume: 8
Pages: 1036
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Publication
26620087 | J:228733
 
First Author: Amano K
Year: 2016
Journal: Bone
Title: Ihh and PTH1R signaling in limb mesenchyme is required for proper segmentation and subsequent formation and growth of digit bones.
Volume: 83
Pages: 256-66
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Publication
19761883 | J:157202
First Author: Maeda Y
Year: 2010
Journal: Bone
Title: Partial rescue of postnatal growth plate abnormalities in Ihh mutants by expression of a constitutively active PTH/PTHrP receptor.
Volume: 46
Issue: 2
Pages: 472-8
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Publication
11517919 | J:175111
First Author: Zhang XM
Year: 2001
Journal: Cell
Title: Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node.
Volume: 106
Issue: 2
Pages: 781-92
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Publication
32108165 | J:297817
First Author: Kasiri S
Year: 2020
Journal: Oncogene
Title: Stromal Hedgehog pathway activation by IHH suppresses lung adenocarcinoma growth and metastasis by limiting reactive oxygen species.
Volume: 39
Issue: 16
Pages: 3258-3275
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Publication
19906844 | J:154905
First Author: Joeng KS
Year: 2009
Journal: Development
Title: The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization.
Volume: 136
Issue: 24
Pages: 4177-85
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Publication
19501129 | J:154499
First Author: Pierre M
Year: 2009
Journal: Exp Hematol
Title: VEGF and IHH rescue definitive hematopoiesis in Gata-4 and Gata-6-deficient murine embryoid bodies.
Volume: 37
Issue: 9
Pages: 1038-53
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GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1745820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7C
Note: Ihh is expressed in the cartilage.
Specimen Label: 7C
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:7264388
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1771322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7286336
Age: embryonic day 14.5
Image: 1D 11Enh-Cre; Sox9
Note: Ihh expression was almost completely lost.
Specimen Label: 1D 11Enh-Cre; Sox9
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7D
Note: Ihh is ectopically expressed in the branchial arches.
Specimen Label: 7D
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7G
Note: Ihh is ectopically expressed in the branchial arches.
Specimen Label: 7G
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:1331157
Age: embryonic day 10.5
Note: No ectopic Ihh expression is detected in mutants.
Specimen Label: not shown
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7E
Note: Ihh is ectopically expressed in the branchial arches.
Specimen Label: 7E
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7H
Note: Ihh is ectopically expressed in the branchial arches.
Specimen Label: 7H
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6473146
Assay Type: RNA in situ
Annotation Date: 2020-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6473192
Age: postnatal day 0
Image: 3A Smad2
Note: The zone of Ihh expression was increased compared with control.
Specimen Label: 3A Smad2
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6473146
Assay Type: RNA in situ
Annotation Date: 2020-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6473192
Age: postnatal day 0
Image: 3A Smad3<-/->
Note: The zone of Ihh expression was increased compared with control.
Specimen Label: 3A Smad3<-/->
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7G
Note: Ihh is also ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7G
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7I
Note: Ihh is ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7I
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7H
Note: Ihh is also ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7H
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7G
Note: Ihh is also ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7G
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7I
Note: Ihh is ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7I
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7H
Note: Ihh is also ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7H
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7264388
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1771321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7286336
Age: embryonic day 13.5
Image: 3B 11Prom-Cre; Sox9
Note: The distance between the two Ihh expression domains was increased in the conditional mutant.
Specimen Label: 3B 11Prom-Cre; Sox9
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7D
Note: Ihh is also ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7D
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7F
Note: Ihh is ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7F
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7E
Note: Ihh is also ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7E
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1725119
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6D/E
Note: Ectopic Ihh expression was not detected in the distal ectoderm and the AER.
Specimen Label: 6D/E
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1724719
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6D/E
Note: Ectopic Ihh expression was not detected in the distal ectoderm and the AER.
Specimen Label: 6D/E
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7D
Note: Ihh is also ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7D
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7F
Note: Ihh is ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7F
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 7E
Note: Ihh is also ectopically expressed in the dorsal and ventral metacarpal region and future elbow.
Specimen Label: 7E
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6D/E
Note: Ectopic Ihh expression in the distal limb bud was quite superficial and was absent in the 'core' mesenchyme.
Specimen Label: 6D/E
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6D/E
Note: Ectopic Ihh expression in the distal limb bud was quite superficial and was absent in the 'core' mesenchyme.
Specimen Label: 6D/E
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1741220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 6C
Note: Ihh expression is down-regulated in the apical region whereas its expression in the anterior limb bud remained strong.
Specimen Label: 6C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1745820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1331157
Age: embryonic day 12.5
Image: 6C
Note: Ihh expression is down-regulated in the apical region whereas its expression in the anterior limb bud remained strong.
Specimen Label: 6C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6B
Note: Ihh expression was detected in the distal limb bud and tail bud. However, at the posterior margin where Shh was normally expressed, no Ihh expression was detected.
Specimen Label: 6B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6B
Note: Ihh expression was detected in the distal limb bud and tail bud. However, at the posterior margin where Shh was normally expressed, no Ihh expression was detected.
Specimen Label: 6B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6B
Note: Ihh expression was detected in the distal limb bud and tail bud. However, at the posterior margin where Shh was normally expressed, no Ihh expression was detected.
Specimen Label: 6B
Detected: true
Specimen Num: 2
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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