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Search results 1 to 100 out of 559 for Ikbkb

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Cardinez C
Year: 2018
Journal: J Exp Med
Title: Gain-of-function IKBKB mutation causes human combined immune deficiency.
Volume: 215
Issue: 11
Pages: 2715-2724
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Publication
First Author: Krishna S
Year: 2012
Journal: J Immunol
Title: Chronic activation of the kinase IKKβ impairs T cell function and survival.
Volume: 189
Issue: 3
Pages: 1209-19
Publication
First Author: Liu J
Year: 2016
Journal: Cell
Title: Inflammation Improves Glucose Homeostasis through IKKβ-XBP1s Interaction.
Volume: 167
Issue: 4
Pages: 1052-1066.e18
Publication
First Author: Swarnkar G
Year: 2014
Journal: PLoS One
Title: Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development.
Volume: 9
Issue: 3
Pages: e91421
Publication
First Author: Page A
Year: 2017
Journal: Mol Cancer Res
Title: IKKβ-Mediated Resistance to Skin Cancer Development Is Ink4a/Arf-Dependent.
Volume: 15
Issue: 9
Pages: 1255-1264
Publication
First Author: Herrmann O
Year: 2005
Journal: Nat Med
Title: IKK mediates ischemia-induced neuronal death.
Volume: 11
Issue: 12
Pages: 1322-9
Publication
First Author: Zhang Y
Year: 2017
Journal: Cell Metab
Title: Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight.
Volume: 25
Issue: 5
Pages: 1091-1102.e4
Publication
First Author: Page A
Year: 2010
Journal: J Invest Dermatol
Title: IKKbeta leads to an inflammatory skin disease resembling interface dermatitis.
Volume: 130
Issue: 6
Pages: 1598-610
Publication
First Author: Otero JE
Year: 2012
Journal: PLoS One
Title: Constitutively active canonical NF-κB pathway induces severe bone loss in mice.
Volume: 7
Issue: 6
Pages: e38694
Publication
First Author: Tsaousidou E
Year: 2014
Journal: Cell Rep
Title: Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance.
Volume: 9
Issue: 4
Pages: 1495-506
Publication
First Author: Xia Y
Year: 2012
Journal: Nat Cell Biol
Title: Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
Volume: 14
Issue: 3
Pages: 257-65
Publication
First Author: Rasoulpour RJ
Year: 2007
Journal: Biol Reprod
Title: NF-kappaB activation elicited by ionizing radiation is proapoptotic in testis.
Volume: 76
Issue: 2
Pages: 279-85
Publication
First Author: Vlantis K
Year: 2011
Journal: J Clin Invest
Title: Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice.
Volume: 121
Issue: 7
Pages: 2781-93
Publication
First Author: Calado DP
Year: 2010
Journal: Cancer Cell
Title: Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma.
Volume: 18
Issue: 6
Pages: 580-9
Publication
First Author: Li Q
Year: 1999
Journal: Science
Title: Severe liver degeneration in mice lacking the IkappaB kinase 2 gene.
Volume: 284
Issue: 5412
Pages: 321-5
Publication
First Author: Chang JH
Year: 2012
Journal: Nat Immunol
Title: Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells.
Volume: 13
Issue: 5
Pages: 481-90
Publication
First Author: Lu H
Year: 2014
Journal: PLoS One
Title: IKK2 inhibition attenuates laser-induced choroidal neovascularization.
Volume: 9
Issue: 1
Pages: e87530
Publication
First Author: Li Q
Year: 2000
Journal: Genes Dev
Title: Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation.
Volume: 14
Issue: 14
Pages: 1729-33
Publication
First Author: Randall CM
Year: 2012
Journal: J Immunol
Title: The MC159 protein from the molluscum contagiosum poxvirus inhibits NF-κB activation by interacting with the IκB kinase complex.
Volume: 188
Issue: 5
Pages: 2371-9
Publication
First Author: Blackburn J
Year: 2015
Journal: J Dent Res
Title: Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.
Volume: 94
Issue: 1
Pages: 121-8
Publication
First Author: He WA
Year: 2013
Journal: J Clin Invest
Title: NF-κB-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia.
Volume: 123
Issue: 11
Pages: 4821-35
Publication
First Author: Busuttil V
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2.
Volume: 107
Issue: 42
Pages: 18061-6
Publication
First Author: Watanabe T
Year: 2010
Journal: J Clin Invest
Title: NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
Volume: 120
Issue: 5
Pages: 1645-62
Publication
First Author: Ridder DA
Year: 2015
Journal: J Exp Med
Title: Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.
Volume: 212
Issue: 10
Pages: 1529-49
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Tanaka M
Year: 1999
Journal: Immunity
Title: Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice.
Volume: 10
Issue: 4
Pages: 421-9
Publication
First Author: Hu MC
Year: 1999
Journal: Oncogene
Title: Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IkappaB kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase.
Volume: 18
Issue: 40
Pages: 5514-24
Publication
First Author: Simonin Y
Year: 2013
Journal: PLoS Pathog
Title: Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis.
Volume: 9
Issue: 3
Pages: e1003234
Publication
First Author: Hidvegi T
Year: 2010
Journal: Science
Title: An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.
Volume: 329
Issue: 5988
Pages: 229-32
Publication
First Author: Koch KS
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Targeted deletion of hepatocyte Ikkbeta confers growth advantages.
Volume: 380
Issue: 2
Pages: 349-54
Publication
First Author: Maeda S
Year: 2003
Journal: Immunity
Title: IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha.
Volume: 19
Issue: 5
Pages: 725-37
Publication
First Author: Kim JH
Year: 2018
Journal: Glia
Title: Astroglia contribute to the pathogenesis of spinocerebellar ataxia Type 1 (SCA1) in a biphasic, stage-of-disease specific manner.
Volume: 66
Issue: 9
Pages: 1972-1987
Publication
First Author: Mourkioti F
Year: 2006
Journal: J Clin Invest
Title: Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration.
Volume: 116
Issue: 11
Pages: 2945-54
Publication
First Author: Röhl M
Year: 2004
Journal: J Clin Invest
Title: Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance.
Volume: 113
Issue: 3
Pages: 474-81
Publication
First Author: Ochaba J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: IKKβ slows Huntington's disease progression in R6/1 mice.
Volume: 116
Issue: 22
Pages: 10952-10961
Publication
First Author: Perez-Nazario N
Year: 2013
Journal: J Immunol
Title: Selective ablation of lung epithelial IKK2 impairs pulmonary Th17 responses and delays the clearance of Pneumocystis.
Volume: 191
Issue: 9
Pages: 4720-30
Publication
First Author: Ko KI
Year: 2019
Journal: Diabetes
Title: Diabetes-Induced NF-κB Dysregulation in Skeletal Stem Cells Prevents Resolution of Inflammation.
Volume: 68
Issue: 11
Pages: 2095-2106
Publication  
First Author: Kirkley KS
Year: 2019
Journal: Neurobiol Dis
Title: Genetic suppression of IKK2/NF-κB in astrocytes inhibits neuroinflammation and reduces neuronal loss in the MPTP-Probenecid model of Parkinson's disease.
Volume: 127
Pages: 193-209
Publication
First Author: Greve B
Year: 2007
Journal: J Immunol
Title: I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis.
Volume: 179
Issue: 1
Pages: 179-85
Publication
First Author: van Diepen JA
Year: 2011
Journal: J Lipid Res
Title: Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice.
Volume: 52
Issue: 5
Pages: 942-50
Publication
First Author: Helsley RN
Year: 2016
Journal: Stem Cells
Title: Targeting IκB kinase β in Adipocyte Lineage Cells for Treatment of Obesity and Metabolic Dysfunctions.
Volume: 34
Issue: 7
Pages: 1883-95
Publication
First Author: Evangelidou M
Year: 2014
Journal: J Immunol
Title: Altered expression of oligodendrocyte and neuronal marker genes predicts the clinical onset of autoimmune encephalomyelitis and indicates the effectiveness of multiple sclerosis-directed therapeutics.
Volume: 192
Issue: 9
Pages: 4122-33
Publication
First Author: Purkayastha S
Year: 2011
Journal: Nat Med
Title: Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB.
Volume: 17
Issue: 7
Pages: 883-7
Publication
First Author: Pasparakis M
Year: 2002
Journal: Nature
Title: TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2.
Volume: 417
Issue: 6891
Pages: 861-6
Publication
First Author: Pallangyo CK
Year: 2015
Journal: J Exp Med
Title: IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
Volume: 212
Issue: 13
Pages: 2253-66
Publication
First Author: Zhang G
Year: 2013
Journal: Nature
Title: Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH.
Volume: 497
Issue: 7448
Pages: 211-6
Publication
First Author: Meng Q
Year: 2011
Journal: J Biol Chem
Title: Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway.
Volume: 286
Issue: 37
Pages: 32324-32
Publication
First Author: Lattke M
Year: 2012
Journal: J Neurosci
Title: Nuclear factor κB activation impairs ependymal ciliogenesis and links neuroinflammation to hydrocephalus formation.
Volume: 32
Issue: 34
Pages: 11511-23
Publication
First Author: Ivovic A
Year: 2017
Journal: Diabetologia
Title: IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents.
Volume: 60
Issue: 10
Pages: 2021-2032
Publication
First Author: Park SH
Year: 2016
Journal: Diabetes
Title: IKKβ Is Essential for Adipocyte Survival and Adaptive Adipose Remodeling in Obesity.
Volume: 65
Issue: 6
Pages: 1616-29
Publication
First Author: Jiao P
Year: 2012
Journal: Endocrinology
Title: Constitutive activation of IKKβ in adipose tissue prevents diet-induced obesity in mice.
Volume: 153
Issue: 1
Pages: 154-65
Publication
First Author: Egan LJ
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium.
Volume: 101
Issue: 8
Pages: 2452-7
Publication
First Author: Chae S
Year: 2006
Journal: J Immunol
Title: Epithelial cell I kappa B-kinase beta has an important protective role in Clostridium difficile toxin A-induced mucosal injury.
Volume: 177
Issue: 2
Pages: 1214-20
Publication
First Author: Broide DH
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium.
Volume: 102
Issue: 49
Pages: 17723-8
Publication
First Author: Miyazaki D
Year: 2013
Journal: Am J Pathol
Title: Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice.
Volume: 183
Issue: 1
Pages: 96-107
Publication
First Author: Koliaraki V
Year: 2015
Journal: J Exp Med
Title: IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer.
Volume: 212
Issue: 13
Pages: 2235-51
Publication
First Author: Li ZW
Year: 1999
Journal: J Exp Med
Title: The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.
Volume: 189
Issue: 11
Pages: 1839-45
Publication
First Author: Tang G
Year: 2001
Journal: Nature
Title: Inhibition of JNK activation through NF-kappaB target genes.
Volume: 414
Issue: 6861
Pages: 313-7
Publication
First Author: Song L
Year: 2006
Journal: J Cell Biol
Title: IKKbeta programs to turn on the GADD45alpha-MKK4-JNK apoptotic cascade specifically via p50 NF-kappaB in arsenite response.
Volume: 175
Issue: 4
Pages: 607-17
Publication
First Author: Wang J
Year: 2007
Journal: Mol Immunol
Title: IKK antagonizes CD95 ligation-mediated apoptosis by regulating NF-kappaB activity.
Volume: 44
Issue: 8
Pages: 2139-43
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Baby.
Publication
First Author: Chen L
Year: 2016
Journal: PLoS One
Title: Corneal Wound Healing Requires IKB kinase β Signaling in Keratocytes.
Volume: 11
Issue: 3
Pages: e0151869
Publication
First Author: Kyrargyri V
Year: 2015
Journal: Glia
Title: Differential contributions of microglial and neuronal IKKβ to synaptic plasticity and associative learning in alert behaving mice.
Volume: 63
Issue: 4
Pages: 549-66
Publication
First Author: Emmanouil M
Year: 2009
Journal: J Immunol
Title: Neuronal I kappa B kinase beta protects mice from autoimmune encephalomyelitis by mediating neuroprotective and immunosuppressive effects in the central nervous system.
Volume: 183
Issue: 12
Pages: 7877-89
Publication
First Author: Arkan MC
Year: 2005
Journal: Nat Med
Title: IKK-beta links inflammation to obesity-induced insulin resistance.
Volume: 11
Issue: 2
Pages: 191-8
Publication      
First Author: SoRelle J
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Impaired
Publication
First Author: Bockhart V
Year: 2009
Journal: J Neurosci
Title: Inhibitor kappaB Kinase beta deficiency in primary nociceptive neurons increases TRP channel sensitivity.
Volume: 29
Issue: 41
Pages: 12919-29
Publication  
First Author: Truitt JM
Year: 2016
Journal: eNeuro
Title: Inhibition of IKKβ Reduces Ethanol Consumption in C57BL/6J Mice.
Volume: 3
Issue: 5
Publication
First Author: Stratis A
Year: 2006
Journal: J Invest Dermatol
Title: Localized inflammatory skin disease following inducible ablation of I kappa B kinase 2 in murine epidermis.
Volume: 126
Issue: 3
Pages: 614-20
Publication
First Author: Kim JE
Year: 2010
Journal: Cell Signal
Title: Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation.
Volume: 22
Issue: 11
Pages: 1645-54
Publication
First Author: Huber MA
Year: 2002
Journal: J Biol Chem
Title: The IKK-2/Ikappa Balpha /NF-kappa B pathway plays a key role in the regulation of CCR3 and eotaxin-1 in fibroblasts. A critical link to dermatitis in Ikappa Balpha -deficient mice.
Volume: 277
Issue: 2
Pages: 1268-75
Publication
First Author: Zandi E
Year: 1999
Journal: Mol Cell Biol
Title: Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex.
Volume: 19
Issue: 7
Pages: 4547-51
Publication
First Author: Chen F
Year: 2006
Journal: J Biol Chem
Title: Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells.
Volume: 281
Issue: 48
Pages: 37142-9
Publication
First Author: Baumann B
Year: 2007
Journal: J Clin Invest
Title: Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo.
Volume: 117
Issue: 6
Pages: 1502-13