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Search results 1 to 100 out of 219 for Il15ra

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0.042s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: IL-15 receptor (IL-15R) composed of IL-15Ralpha, IL-2/15Rbeta (CD122), and gamma(c) (CD132) subunits []. IL-15 is a cytokine that plays an important role in innate and adaptive immunity []. Syk kinase interacts with IL-15Ralpha and may play a key role in mediating IL-15-induced signal transduction [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Anderson DM
Year: 1995
Journal: J Biol Chem
Title: Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes.
Volume: 270
Issue: 50
Pages: 29862-9
Publication  
First Author: Loro E
Year: 2017
Journal: Bone
Title: IL15RA is required for osteoblast function and bone mineralization.
Volume: 103
Pages: 20-30
Publication
First Author: O'Connell G
Year: 2015
Journal: J Appl Physiol (1985)
Title: Muscle-specific deletion of exons 2 and 3 of the IL15RA gene in mice: effects on contractile properties of fast and slow muscles.
Volume: 118
Issue: 4
Pages: 437-48
Protein
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 155  
Fragment?: true
Publication
First Author: Ratthé C
Year: 2004
Journal: J Leukoc Biol
Title: Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain.
Volume: 76
Issue: 1
Pages: 162-8
GXD Expression  
Probe: MGI:7336711
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7336721
Age: embryonic day 14.5
Note: At E14.5, Il15ra staining was detected in the axons of olfactory neurons, and was co-localized with Gap43, a marker of immature neurons.
Specimen Label: 1f
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7336711
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7336721
Age: embryonic day 18.5
Note: At E18.5, Il15ra staining was detected in the axons of olfactory neurons, where it overlapped with OMP, a marker of olfactory receptor neurons.
Specimen Label: 1h
Detected: true
Specimen Num: 3
Publication
First Author: Sato N
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells.
Volume: 104
Issue: 2
Pages: 588-93
Publication
First Author: Wu Z
Year: 2008
Journal: Blood
Title: The IL-15 receptor {alpha} chain cytoplasmic domain is critical for normal IL-15Ralpha function but is not required for trans-presentation.
Volume: 112
Issue: 12
Pages: 4411-9
Publication  
First Author: Loro E
Year: 2019
Journal: Front Physiol
Title: Effect of Interleukin-15 Receptor Alpha Ablation on the Metabolic Responses to Moderate Exercise Simulated by in vivo Isometric Muscle Contractions.
Volume: 10
Pages: 1439
Publication  
First Author: Loro E
Year: 2018
Journal: J Cell Sci
Title: Mitochondrial ultrastructural adaptations in fast muscles of mice lacking IL15RA.
Volume: 131
Issue: 21
Publication
First Author: Pistilli EE
Year: 2011
Journal: J Clin Invest
Title: Loss of IL-15 receptor α alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles.
Volume: 121
Issue: 8
Pages: 3120-32
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Bulanova E
Year: 2003
Journal: J Immunol
Title: Mast cells express novel functional IL-15 receptor alpha isoforms.
Volume: 170
Issue: 10
Pages: 5045-55
Publication
First Author: Lodolce JP
Year: 1998
Journal: Immunity
Title: IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation.
Volume: 9
Issue: 5
Pages: 669-76
Publication
First Author: Ochoa MC
Year: 2012
Journal: PLoS One
Title: Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy.
Volume: 7
Issue: 12
Pages: e52370
Publication
First Author: Pistilli EE
Year: 2013
Journal: Cytokine
Title: IL-15Rα deficiency leads to mitochondrial and myofiber differences in fast mouse muscles.
Volume: 61
Issue: 1
Pages: 41-5
Publication
First Author: Emoto M
Year: 2010
Journal: Infect Immun
Title: Alpha-galactosylceramide promotes killing of Listeria monocytogenes within the macrophage phagosome through invariant NKT-cell activation.
Volume: 78
Issue: 6
Pages: 2667-76
Publication
First Author: Ota N
Year: 2010
Journal: J Immunol
Title: No requirement of trans presentations of IL-15 for human CD8 T cell proliferation.
Volume: 185
Issue: 10
Pages: 6041-8
Publication
First Author: Lodolce JP
Year: 2001
Journal: J Exp Med
Title: T cell-independent interleukin 15Ralpha signals are required for bystander proliferation.
Volume: 194
Issue: 8
Pages: 1187-94
Publication
First Author: Su YC
Year: 2010
Journal: J Immunol
Title: Effector function-deficient memory CD8+ T cells clonally expand in the liver and give rise to peripheral memory CD8+ T cells.
Volume: 185
Issue: 12
Pages: 7498-506
Publication
First Author: Koka R
Year: 2003
Journal: J Exp Med
Title: Interleukin (IL)-15R[alpha]-deficient natural killer cells survive in normal but not IL-15R[alpha]-deficient mice.
Volume: 197
Issue: 8
Pages: 977-84
Publication
First Author: He Y
Year: 2010
Journal: J Neurosci
Title: Interleukin-15 receptor is essential to facilitate GABA transmission and hippocampal-dependent memory.
Volume: 30
Issue: 13
Pages: 4725-34
Publication
First Author: Lee JM
Year: 2004
Journal: J Immunol
Title: IL-15Ralpha is a negative regulator of TCR-activated proliferation in CD4+ T cells.
Volume: 173
Issue: 5
Pages: 3155-64
Publication
First Author: Chow KP
Year: 2012
Journal: PLoS One
Title: Selective reduction of post-selection CD8 thymocyte proliferation in IL-15Rα deficient mice.
Volume: 7
Issue: 3
Pages: e33152
Publication
First Author: Chang CL
Year: 2011
Journal: J Immunol
Title: IL-15Rα of radiation-resistant cells is necessary and sufficient for thymic invariant NKT cell survival and functional maturation.
Volume: 187
Issue: 3
Pages: 1235-42
Publication
First Author: Chen JP
Year: 2005
Journal: Eur J Immunol
Title: Reduced 2,4-dinitro-1-fluorobenzene-induced contact hypersensitivity response in IL-15 receptor alpha-deficient mice correlates with diminished CCL5/RANTES and CXCL10/IP-10 expression.
Volume: 35
Issue: 3
Pages: 690-8
Publication
First Author: Wu X
Year: 2010
Journal: J Neurochem
Title: Expression and signaling of novel IL15Ralpha splicing variants in cerebral endothelial cells of the blood-brain barrier.
Volume: 114
Issue: 1
Pages: 122-9
Publication
First Author: Burkett PR
Year: 2004
Journal: J Exp Med
Title: Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis.
Volume: 200
Issue: 7
Pages: 825-34
Publication
First Author: Bulanova E
Year: 2007
Journal: J Biol Chem
Title: Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15.
Volume: 282
Issue: 18
Pages: 13167-79
Publication
First Author: Burkett PR
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory.
Volume: 100
Issue: 8
Pages: 4724-9
Publication  
First Author: O'Connell GC
Year: 2015
Journal: Mitochondrion
Title: IL-15Rα deficiency in skeletal muscle alters respiratory function and the proteome of mitochondrial subpopulations independent of changes to the mitochondrial genome.
Volume: 25
Pages: 87-97
GXD Expression      
Probe: MGI:7336716
Assay Type: RT-PCR
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760620
Stage: TS20
Assay Id: MGI:7336718
Age: embryonic day 12.5
Specimen Label: E12.5 OE
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7336716
Assay Type: RT-PCR
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:7336718
Age: embryonic day 14.5
Specimen Label: E14.5 OE
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7336716
Assay Type: RT-PCR
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760626
Stage: TS26
Assay Id: MGI:7336718
Age: embryonic day 18.5
Specimen Label: E18.5 OE
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7336716
Assay Type: RT-PCR
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760628
Stage: TS28
Assay Id: MGI:7336718
Age: postnatal adult
Specimen Label: Adult OE
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7336716
Assay Type: RT-PCR
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:7336718
Age: postnatal adult
Specimen Label: Adult OB
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585519
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585519
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the inner neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Uniform
Stage: TS28
Assay Id: MGI:3585519
Age: postnatal day 4-5
Image: P4/5
Note: Expression was panretinal.
Specimen Label: P4/5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585519
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585519
Age: postnatal day 6-7
Image: P6/7
Note: Expression was detected in the inner nuclear layer and tentatively in amacrine cells.
Specimen Label: P6/7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585519
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585519
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585519
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585519
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1085419
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585519
Age: postnatal day 6
Note: Expression was widespread.
Specimen Label: CNS
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7336711
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760620
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7336721
Age: embryonic day 12.5
Specimen Label: not shown
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7336711
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7336721
Age: embryonic day 14.5
Specimen Label: 1f
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7336711
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7336721
Age: embryonic day 18.5
Specimen Label: 1h
Detected: true
Specimen Num: 3
Publication
First Author: Giri JG
Year: 1995
Journal: EMBO J
Title: Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor.
Volume: 14
Issue: 15
Pages: 3654-63
Publication
First Author: Budagian V
Year: 2004
Journal: J Biol Chem
Title: Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17).
Volume: 279
Issue: 39
Pages: 40368-75
Publication
First Author: Baumann NS
Year: 2018
Journal: PLoS Pathog
Title: Tissue maintenance of CMV-specific inflationary memory T cells by IL-15.
Volume: 14
Issue: 4
Pages: e1006993
Publication
First Author: Castillo EF
Year: 2009
Journal: J Immunol
Title: Dendritic cells support the in vivo development and maintenance of NK cells via IL-15 trans-presentation.
Volume: 183
Issue: 8
Pages: 4948-56
Publication
First Author: Stonier SW
Year: 2008
Journal: Blood
Title: Dendritic cells drive memory CD8 T-cell homeostasis via IL-15 transpresentation.
Volume: 112
Issue: 12
Pages: 4546-54
Publication
First Author: Mortier E
Year: 2008
Journal: J Exp Med
Title: IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation.
Volume: 205
Issue: 5
Pages: 1213-25
Publication
First Author: Patel S
Year: 2016
Journal: Immunology
Title: Vitamin A or E and a catechin synergize as vaccine adjuvant to enhance immune responses in mice by induction of early interleukin-15 but not interleukin-1β responses.
Volume: 148
Issue: 4
Pages: 352-62
Publication
First Author: Kohlhapp FJ
Year: 2012
Journal: J Immunol
Title: CD8(+) T cells sabotage their own memory potential through IFN-γ-dependent modification of the IL-12/IL-15 receptor α axis on dendritic cells.
Volume: 188
Issue: 8
Pages: 3639-47
Publication
First Author: Koka R
Year: 2004
Journal: J Immunol
Title: Cutting edge: murine dendritic cells require IL-15R alpha to prime NK cells.
Volume: 173
Issue: 6
Pages: 3594-8
Publication
First Author: Bergamaschi C
Year: 2012
Journal: Blood
Title: Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum.
Volume: 120
Issue: 1
Pages: e1-8
Publication
First Author: Loro E
Year: 2015
Journal: Am J Physiol Regul Integr Comp Physiol
Title: IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity.
Volume: 309
Issue: 8
Pages: R835-44
Publication
First Author: Yajima T
Year: 2006
Journal: J Immunol
Title: IL-15 regulates CD8+ T cell contraction during primary infection.
Volume: 176
Issue: 1
Pages: 507-15
Publication
First Author: Sandau MM
Year: 2004
Journal: J Immunol
Title: Cutting edge: transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15R alpha by the same cells.
Volume: 173
Issue: 11
Pages: 6537-41
Publication
First Author: Castillo EF
Year: 2010
Journal: Blood
Title: Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation.
Volume: 116
Issue: 14
Pages: 2494-503
Publication
First Author: Sato N
Year: 2011
Journal: Blood
Title: Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15-transgenic mice requires the cis expression of IL-15Rα.
Volume: 117
Issue: 15
Pages: 4032-40
Publication
First Author: Rückert R
Year: 2003
Journal: Eur J Immunol
Title: Dendritic cell-derived IL-15 controls the induction of CD8 T cell immune responses.
Volume: 33
Issue: 12
Pages: 3493-503
Publication
First Author: Zhou X
Year: 2019
Journal: Nat Immunol
Title: The deubiquitinase Otub1 controls the activation of CD8+ T cells and NK cells by regulating IL-15-mediated priming.
Volume: 20
Issue: 7
Pages: 879-889
Publication
First Author: O'Connell GC
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Interleukin-15 directly stimulates pro-oxidative gene expression in skeletal muscle in-vitro via a mechanism that requires interleukin-15 receptor alpha.
Volume: 458
Issue: 3
Pages: 614-9
Publication
First Author: Ma LJ
Year: 2009
Journal: J Immunol
Title: Trans-presentation of IL-15 by intestinal epithelial cells drives development of CD8alphaalpha IELs.
Volume: 183
Issue: 2
Pages: 1044-54