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Search results 1 to 100 out of 735 for Il18

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Hits by Pathway

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Type Details Score
Gene
3606 | IL18
Type: gene
Organism: human
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Gene
395312 | IL18
Type: gene
Organism: chicken
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Gene
574151 | IL18
Type: gene
Organism: macaque, rhesus
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Gene
281249 | IL18
Type: gene
Organism: cattle
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Gene
108648098 | il18
Type: gene
Organism: frog, western clawed
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Gene
29197 | Il18
Type: gene
Organism: rat
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Gene
403796 | IL18
Type: gene
Organism: dog, domestic
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Gene
739011 | IL18
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:107936 | Il18
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
38139000 | J:343724
 
First Author: Yamanishi K
Year: 2023
Journal: Int J Mol Sci
Title: Molecular Mechanisms of IL18 in Disease.
Volume: 24
Issue: 24
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Publication
30127003 | J:265540
First Author: Tzeng TC
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.
Volume: 115
Issue: 36
Pages: 9002-9007
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GXD Expression
GXD Expression
   
Probe: MGI:3056620
Assay Type: RT-PCR
Annotation Date: 2004-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3505773
Age: postnatal week 9.5
Image: 4
Specimen Label: Th1 Il18 9.5W WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3056620
Assay Type: RT-PCR
Annotation Date: 2004-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3505773
Age: postnatal week 9.5
Image: 4
Specimen Label: Th1 Il18 9.5W KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3056620
Assay Type: RT-PCR
Annotation Date: 2004-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3505773
Age: postnatal month 9
Image: 4
Specimen Label: Th1 Il18 9M WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3056620
Assay Type: RT-PCR
Annotation Date: 2004-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3505773
Age: postnatal month 9
Image: 4
Specimen Label: Th1 Il18 9M KO
Detected: true
Specimen Num: 4
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Publication
35675813 | J:342800
First Author: Zhang X
Year: 2022
Journal: Dev Cell
Title: IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells.
Volume: 57
Issue: 12
Pages: 1496-1511.e6
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Publication
24565845 | J:219136
First Author: Takenaka S
Year: 2014
Journal: Biochem Biophys Res Commun
Title: The progression of comorbidity in IL-18 transgenic chronic obstructive pulmonary disease mice model.
Volume: 445
Issue: 3
Pages: 597-601
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Publication
25680273 | J:223829
First Author: Muñoz M
Year: 2015
Journal: Immunity
Title: Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection.
Volume: 42
Issue: 2
Pages: 321-331
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Publication
25934945 | J:226374
First Author: Inoue T
Year: 2015
Journal: Reproduction
Title: Endogenous interleukin 18 regulates testicular germ cell apoptosis during endotoxemia.
Volume: 150
Issue: 2
Pages: 105-14
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Publication
36450731 | J:331958
First Author: Qie J
Year: 2022
Journal: Nat Commun
Title: Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues.
Volume: 13
Issue: 1
Pages: 7389
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Publication
33181835 | J:312133
First Author: Gupta A
Year: 2021
Journal: Blood
Title: IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias.
Volume: 137
Issue: 9
Pages: 1208-1218
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Publication
18386818 | J:138517
First Author: Hacker E
Year: 2008
Journal: Int J Cancer
Title: Reduced expression of IL-18 is a marker of ultraviolet radiation-induced melanomas.
Volume: 123
Issue: 1
Pages: 227-31
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Publication
26638073 | J:227990
First Author: Nowarski R
Year: 2015
Journal: Cell
Title: Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.
Volume: 163
Issue: 6
Pages: 1444-56
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Publication
29847790 | J:271112
First Author: Clark SE
Year: 2018
Journal: Cell Rep
Title: A Batf3/Nlrp3/IL-18 Axis Promotes Natural Killer Cell IL-10 Production during Listeria monocytogenes Infection.
Volume: 23
Issue: 9
Pages: 2582-2594
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Publication
26656097 | J:249916
 
First Author: Pazos P
Year: 2015
Journal: Sci Rep
Title: Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice.
Volume: 5
Pages: 17977
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Publication
32687059 | J:313536
   
First Author: Peligero-Cruz C
Year: 2020
Journal: Elife
Title: IL18 signaling promotes homing of mature Tregs into the thymus.
Volume: 9
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Publication
17400729 | J:147547
First Author: Hoshino T
Year: 2007
Journal: Am J Respir Crit Care Med
Title: Pulmonary inflammation and emphysema: role of the cytokines IL-18 and IL-13.
Volume: 176
Issue: 1
Pages: 49-62
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Publication
29326099 | J:261562
First Author: Weiss ES
Year: 2018
Journal: Blood
Title: Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.
Volume: 131
Issue: 13
Pages: 1442-1455
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Publication
25600646 | J:317002
First Author: Li S
Year: 2015
Journal: Cancer Res
Title: TLR2 limits development of hepatocellular carcinoma by reducing IL18-mediated immunosuppression.
Volume: 75
Issue: 6
Pages: 986-95
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Publication
24827856 | J:217355
First Author: Kupz A
Year: 2014
Journal: PLoS One
Title: In vivo IFN-γ secretion by NK cells in response to Salmonella typhimurium requires NLRC4 inflammasomes.
Volume: 9
Issue: 5
Pages: e97418
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Publication
33178225 | J:336797
 
First Author: Sasaki Y
Year: 2020
Journal: Front Immunol
Title: Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation.
Volume: 11
Pages: 591713
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Publication
26099046 | J:224865
First Author: Wang J
Year: 2015
Journal: Nat Med
Title: Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.
Volume: 21
Issue: 7
Pages: 820-6
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Publication
12151598 | J:78602
First Author: Konishi H
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions.
Volume: 99
Issue: 17
Pages: 11340-5
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Publication
29282220 | J:261888
First Author: Deswaerte V
Year: 2018
Journal: Cancer Res
Title: Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism.
Volume: 78
Issue: 5
Pages: 1293-1307
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Protein Coding Gene
MGP_CAROLIEiJ_G0032186 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034780 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034761 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034689 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034753 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034463 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_107936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035273 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033785 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034435 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034594 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034535 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034675 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034578 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035294 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033490 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033898 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015054 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033325 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
7477296 | J:35492
First Author: Okamura H
Year: 1995
Journal: Nature
Title: Cloning of a new cytokine that induces IFN-gamma production by T cells.
Volume: 378
Issue: 6552
Pages: 88-91
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Publication
22307326 | J:184486
First Author: Oertli M
Year: 2012
Journal: J Clin Invest
Title: DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection.
Volume: 122
Issue: 3
Pages: 1082-96
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Publication
17433555 | J:122031
First Author: Sugama S
Year: 2007
Journal: Neuroscience
Title: Stress induced morphological microglial activation in the rodent brain: involvement of interleukin-18.
Volume: 146
Issue: 3
Pages: 1388-99
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Publication
17049054 | J:135970
First Author: Wyburn K
Year: 2006
Journal: Am J Transplant
Title: Interleukin-18 affects local cytokine expression but does not impact on the development of kidney allograft rejection.
Volume: 6
Issue: 11
Pages: 2612-21
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Publication
31518161 | J:310500
First Author: Li W
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Impaired function of aorta and perivascular adipose tissue in IL-18-deficient mice.
Volume: 317
Issue: 5
Pages: H1142-H1156
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Publication
17316614 | J:141588
First Author: Zhang XM
Year: 2007
Journal: Exp Neurol
Title: IL-18 deficiency aggravates kainic acid-induced hippocampal neurodegeneration in C57BL/6 mice due to an overcompensation by IL-12.
Volume: 205
Issue: 1
Pages: 64-73
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Publication
19129255 | J:145703
First Author: He Z
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Macrophages are not the source of injurious interleukin-18 in ischemic acute kidney injury in mice.
Volume: 296
Issue: 3
Pages: F535-42
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Publication
15792964 | J:104755
First Author: Nakatani-Okuda A
Year: 2005
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Protection against bleomycin-induced lung injury by IL-18 in mice.
Volume: 289
Issue: 2
Pages: L280-7
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Publication
17578927 | J:122588
First Author: Zorrilla EP
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency.
Volume: 104
Issue: 26
Pages: 11097-102
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Publication
12742650 | J:119043
First Author: Zwijnenburg PJ
Year: 2003
Journal: J Neuroimmunol
Title: Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis.
Volume: 138
Issue: 1-2
Pages: 31-7
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Publication
16959946 | J:120594
First Author: Seino H
Year: 2007
Journal: Am J Physiol Gastrointest Liver Physiol
Title: IL-18 mediates the formation of stress-induced, histamine-dependent gastric lesions.
Volume: 292
Issue: 1
Pages: G262-7
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Publication
15555769 | J:104826
First Author: Hedtjärn M
Year: 2005
Journal: Neurosci Lett
Title: White matter injury in the immature brain: role of interleukin-18.
Volume: 373
Issue: 1
Pages: 16-20
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Publication
12122053 | J:124249
First Author: Hedtjärn M
Year: 2002
Journal: J Neurosci
Title: Interleukin-18 involvement in hypoxic-ischemic brain injury.
Volume: 22
Issue: 14
Pages: 5910-9
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Publication
17664259 | J:125285
First Author: Wieland CW
Year: 2007
Journal: Infect Immun
Title: Interleukin 18 participates in the early inflammatory response and bacterial clearance during pneumonia caused by nontypeable Haemophilus influenzae.
Volume: 75
Issue: 10
Pages: 5068-72
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Publication
34183442 | J:314234
 
First Author: Kandikattu HK
Year: 2021
Journal: Life Sci Alliance
Title: Macrophages-induced IL-18-mediated eosinophilia promotes characteristics of pancreatic malignancy.
Volume: 4
Issue: 8
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Publication
15606801 | J:94687
First Author: Van Der Sluijs KF
Year: 2005
Journal: Immunology
Title: Enhanced viral clearance in interleukin-18 gene-deficient mice after pulmonary infection with influenza A virus.
Volume: 114
Issue: 1
Pages: 112-20
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Publication
15350655 | J:93613
First Author: Sugama S
Year: 2004
Journal: Neuroscience
Title: Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment.
Volume: 128
Issue: 2
Pages: 451-8
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Publication
17947451 | J:130516
First Author: Halpern MD
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Decreased development of necrotizing enterocolitis in IL-18-deficient mice.
Volume: 294
Issue: 1
Pages: G20-6
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Publication
18826499 | J:142814
First Author: Yamagata S
Year: 2008
Journal: Clin Exp Immunol
Title: Interleukin-18-deficient mice exhibit diminished chronic inflammation and airway remodelling in ovalbumin-induced asthma model.
Volume: 154
Issue: 3
Pages: 295-304
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Publication
17250807 | J:118183
First Author: Colston JT
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Interleukin-18 knockout mice display maladaptive cardiac hypertrophy in response to pressure overload.
Volume: 354
Issue: 2
Pages: 552-8
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Publication
15385528 | J:93126
First Author: Nakasone C
Year: 2004
Journal: Infect Immun
Title: Limited role for interleukin-18 in the host protection response to pulmonary infection with Pseudomonas aeruginosa in mice.
Volume: 72
Issue: 10
Pages: 6176-80
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Publication
26009021 | J:329084
First Author: Sousa LM
Year: 2015
Journal: Cytokine
Title: IL-18 contributes to susceptibility to Leishmania amazonensis infection by macrophage-independent mechanisms.
Volume: 74
Issue: 2
Pages: 327-30
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Publication
29603367 | J:264512
First Author: El-Darawish Y
Year: 2018
Journal: J Leukoc Biol
Title: Frontline Science: IL-18 primes murine NK cells for proliferation by promoting protein synthesis, survival, and autophagy.
Volume: 104
Issue: 2
Pages: 253-264
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Publication
31445353 | J:293641
 
First Author: Suehiro C
Year: 2019
Journal: Atherosclerosis
Title: Deletion of interleukin-18 attenuates abdominal aortic aneurysm formation.
Volume: 289
Pages: 14-20
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Publication
30981863 | J:283016
 
First Author: Yamanishi K
Year: 2019
Journal: Neuroscience
Title: Interleukin-18-deficient mice develop hippocampal abnormalities related to possible depressive-like behaviors.
Volume: 408
Pages: 147-160
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Publication
15322198 | J:92673
First Author: Akhiani AA
Year: 2004
Journal: J Immunol
Title: Vaccine-induced immunity against Helicobacter pylori infection is impaired in IL-18-deficient mice.
Volume: 173
Issue: 5
Pages: 3348-56
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Publication
11504551 | J:71064
First Author: Mori I
Year: 2001
Journal: Virology
Title: Impaired microglial activation in the brain of IL-18-gene-disrupted mice after neurovirulent influenza A virus infection.
Volume: 287
Issue: 1
Pages: 163-70
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Publication
19141531 | J:150555
First Author: Nishida K
Year: 2009
Journal: FASEB J
Title: Interleukin-18 is a crucial determinant of vulnerability of the mouse rectum to psychosocial stress.
Volume: 23
Issue: 6
Pages: 1797-805
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Publication
26747780 | J:232652
First Author: Bruns DR
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Genetic ablation of interleukin-18 does not attenuate hypobaric hypoxia-induced right ventricular hypertrophy.
Volume: 310
Issue: 6
Pages: L542-50
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Publication
17218016 | J:124505
First Author: Duan RS
Year: 2007
Journal: J Neuroimmunol
Title: IL-18 deficiency inhibits both Th1 and Th2 cytokine production but not the clinical symptoms in experimental autoimmune neuritis.
Volume: 183
Issue: 1-2
Pages: 162-7
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Publication
15122309 | J:92254
First Author: Qiao H
Year: 2004
Journal: Lab Invest
Title: Abnormal retinal vascular development in IL-18 knockout mice.
Volume: 84
Issue: 8
Pages: 973-80
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Publication
27288439 | J:236263
First Author: Li W
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Dysfunction of mitochondria and deformed gap junctions in the heart of IL-18-deficient mice.
Volume: 311
Issue: 2
Pages: H313-25
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Publication
37068092 | J:340894
First Author: Johnson AF
Year: 2023
Journal: PLoS Pathog
Title: Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection.
Volume: 19
Issue: 4
Pages: e1011321
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Publication
32272223 | J:309307
 
First Author: Wu D
Year: 2020
Journal: Brain Behav Immun
Title: Interleukin-18 from neurons and microglia mediates depressive behaviors in mice with post-stroke depression.
Volume: 88
Pages: 411-420
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Publication
17234681 | J:121444
First Author: Qiao H
Year: 2007
Journal: J Leukoc Biol
Title: Interleukin-18 regulates pathological intraocular neovascularization.
Volume: 81
Issue: 4
Pages: 1012-21
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Publication
16723395 | J:110807
First Author: Terada M
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by Staphylococcus aureus product in mice.
Volume: 103
Issue: 23
Pages: 8816-21
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Publication
10816504 | J:62263
First Author: Hochholzer P
Year: 2000
Journal: Infect Immun
Title: Role of interleukin-18 (IL-18) during lethal shock: decreased lipopolysaccharide sensitivity but normal superantigen reaction in IL-18-deficient mice.
Volume: 68
Issue: 6
Pages: 3502-8
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Publication
18573894 | J:138759
First Author: Lochner M
Year: 2008
Journal: Infect Immun
Title: Decreased susceptibility of mice to infection with Listeria monocytogenes in the absence of interleukin-18.
Volume: 76
Issue: 9
Pages: 3881-90
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Publication
16162269 | J:101028
First Author: Dalpke AH
Year: 2005
Journal: Immunology
Title: Differential effects of CpG-DNA in Toll-like receptor-2/-4/-9 tolerance and cross-tolerance.
Volume: 116
Issue: 2
Pages: 203-12
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Publication
10453027 | J:86621
First Author: Wei XQ
Year: 1999
Journal: J Immunol
Title: Altered immune responses and susceptibility to Leishmania major and Staphylococcus aureus infection in IL-18-deficient mice.
Volume: 163
Issue: 5
Pages: 2821-8
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Publication
15234532 | J:110960
First Author: Wei XQ
Year: 2004
Journal: Immunol Lett
Title: Host genetic background determines whether IL-18 deficiency results in increased susceptibility or resistance to murine Leishmania major infection.
Volume: 94
Issue: 1-2
Pages: 35-7
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Publication
29195684 | J:329838
 
First Author: Lisboa SF
Year: 2018
Journal: J Neuroimmunol
Title: Mice lacking interleukin-18 gene display behavioral changes in animal models of psychiatric disorders: Possible involvement of immunological mechanisms.
Volume: 314
Pages: 58-66
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Publication
16879623 | J:118524
First Author: Mullen AB
Year: 2006
Journal: Immunology
Title: Endogenous interleukin-18 is involved in immunity to Leishmania donovani but its absence does not adversely influence the therapeutic activity of sodium stibogluconate.
Volume: 119
Issue: 3
Pages: 348-54
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Publication
11133864 | J:66542
First Author: Jiang HR
Year: 2001
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