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Search results 1 to 100 out of 114 for Il18bp

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
10068 | IL18BP
Type: gene
Organism: human
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Gene
101732536 | il18bp
Type: gene
Organism: frog, western clawed
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Gene
107052452 | IL18BP
Type: gene
Organism: chicken
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Gene
84388 | Il18bp
Type: gene
Organism: rat
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Gene
476818 | IL18BP
Type: gene
Organism: dog, domestic
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Gene
748234 | IL18BP
Type: gene
Organism: chimpanzee
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Gene
617470 | IL18BP
Type: gene
Organism: cattle
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Gene
100144607 | IL18BP
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1333800 | Il18bp
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR039681 | IL18BP
Type: Family
Description: Interleukin-18-binding protein (IL18BP) isoform A binds to IL-18 and inhibits its activity []. It is required for normal NK cell abundance and function and also contributes to maintaining steady-state levels of circulating IL-18 [].
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Publication
10655506 | J:60183
First Author: Kim SH
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18.
Volume: 97
Issue: 3
Pages: 1190-5
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Publication
28900426 | J:255309
 
First Author: Harms RZ
Year: 2017
Journal: Front Immunol
Title: Interleukin (IL)-18 Binding Protein Deficiency Disrupts Natural Killer Cell Maturation and Diminishes Circulating IL-18.
Volume: 8
Pages: 1020
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Protein
Q9Z0M9
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
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Protein
A0A1B0GSF2
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Protein
A0A1B0GT50
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false
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Publication
26638073 | J:227990
First Author: Nowarski R
Year: 2015
Journal: Cell
Title: Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.
Volume: 163
Issue: 6
Pages: 1444-56
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Protein Coding Gene
MGP_CAROLIEiJ_G0030074 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032596 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032572 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032583 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032297 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1333800 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033080 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032263 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032415 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032371 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032504 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032405 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033102 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031341 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031740 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013295 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031185 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10094485 | J:53429
First Author: Aizawa Y
Year: 1999
Journal: FEBS Lett
Title: Cloning and expression of interleukin-18 binding protein.
Volume: 445
Issue: 2-3
Pages: 338-42
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Publication
10023777 | J:52523
First Author: Novick D
Year: 1999
Journal: Immunity
Title: Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.
Volume: 10
Issue: 1
Pages: 127-36
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Publication
10329540 | J:54923
First Author: Xiang Y
Year: 1999
Journal: Virology
Title: Identification of human and mouse homologs of the MC51L-53L-54L family of secreted glycoproteins encoded by the Molluscum contagiosum poxvirus.
Volume: 257
Issue: 2
Pages: 297-302
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Publication
37074208 | J:337716
First Author: Harel M
Year: 2023
Journal: J Immunol
Title: IL-18 Binding Protein-Producing Cells Attenuate Anemia in Murine Macrophage Activation Syndrome.
Volume: 210
Issue: 11
Pages: 1790-1803
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Publication
32651219 | J:294227
First Author: Harel M
Year: 2020
Journal: J Immunol
Title: Production of IL-18 Binding Protein by Radiosensitive and Radioresistant Cells in CpG-Induced Macrophage Activation Syndrome.
Volume: 205
Issue: 4
Pages: 1167-1175
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691369
Age: postnatal adult
Image: UC Davis_1864714
Note: vas deferens
Specimen Label: UC Davis_1864714
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691369
Age: postnatal adult
Image: UC Davis_1864715
Note: vas deferens
Specimen Label: UC Davis_1864715
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_01
Specimen Label: euxassay_010765_01
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_02
Specimen Label: euxassay_010765_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_03
Specimen Label: euxassay_010765_03
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_04
Specimen Label: euxassay_010765_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_05
Specimen Label: euxassay_010765_05
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_06
Specimen Label: euxassay_010765_06
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_07
Specimen Label: euxassay_010765_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_08
Specimen Label: euxassay_010765_08
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_09
Specimen Label: euxassay_010765_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_10
Specimen Label: euxassay_010765_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_11
Specimen Label: euxassay_010765_11
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_12
Specimen Label: euxassay_010765_12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_13
Specimen Label: euxassay_010765_13
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_14
Specimen Label: euxassay_010765_14
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_15
Specimen Label: euxassay_010765_15
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_16
Specimen Label: euxassay_010765_16
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_17
Specimen Label: euxassay_010765_17
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_18
Specimen Label: euxassay_010765_18
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_19
Specimen Label: euxassay_010765_19
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_20
Specimen Label: euxassay_010765_20
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_21
Specimen Label: euxassay_010765_21
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_22
Specimen Label: euxassay_010765_22
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
 
Probe: MGI:4416738
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825572
Age: embryonic day 14.5
Image: euxassay_010765_23
Specimen Label: euxassay_010765_23
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691369
Age: postnatal adult
Image: UC Davis_1864708
Specimen Label: UC Davis_1864708
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691369
Age: postnatal adult
Image: UC Davis_1864712
Specimen Label: UC Davis_1864712
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691369
Age: postnatal adult
Image: UC Davis_1864713
Specimen Label: UC Davis_1864713
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691369
Age: postnatal adult
Image: UC Davis_1864711
Specimen Label: UC Davis_1864711
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691369
Age: postnatal adult
Image: UC Davis_1864710
Specimen Label: UC Davis_1864710
Detected: true
Specimen Num: 2
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Publication
37415987 | J:337717
 
First Author: Fauteux-Daniel S
Year: 2023
Journal: Front Immunol
Title: The role of interleukin-18 and interleukin-18 binding protein in K/BxN serum transfer-induced arthritis.
Volume: 14
Pages: 1215364
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Publication
20644165 | J:162621
First Author: Millward JM
Year: 2010
Journal: J Immunol
Title: Inflammation in the central nervous system and Th17 responses are inhibited by IFN-gamma-Induced IL-18 binding protein.
Volume: 185
Issue: 4
Pages: 2458-66
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Publication
31747600 | J:287272
First Author: Castillo-Dela Cruz P
Year: 2019
Journal: Cell Rep
Title: Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products.
Volume: 29
Issue: 8
Pages: 2270-2283.e7
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Publication
32581358 | J:291344
First Author: Zhou T
Year: 2020
Journal: Nature
Title: IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy.
Volume: 583
Issue: 7817
Pages: 609-614
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Publication
29295842 | J:261967
First Author: Girard-Guyonvarc'h C
Year: 2018
Journal: Blood
Title: Unopposed IL-18 signaling leads to severe TLR9-induced macrophage activation syndrome in mice.
Volume: 131
Issue: 13
Pages: 1430-1441
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Publication
38906145 | J:353090
     
First Author: Mertens RT
Year: 2024
Journal: Immunity
Title: A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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First Author: Velocigene
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First Author: The Gene Ontology Consortium
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Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
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Journal: Database Release
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First Author: Okazaki Y
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Journal: Nature
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First Author: The Gene Ontology Consortium
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First Author: Mouse Genome Informatics Scientific Curators
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First Author: MGI Genome Annotation Group and UniGene Staff
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First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
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First Author: Allen Institute for Brain Science
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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