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Search results 1 to 100 out of 183 for Il18r1

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Hits by Pathway

Hits by Strain

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Type Details Score
Gene
8809 | IL18R1
Type: gene
Organism: human
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Gene
459463 | IL18R1
Type: gene
Organism: chimpanzee
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Gene
407221 | IL18R1
Type: gene
Organism: cattle
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Gene
418717 | IL18R1
Type: gene
Organism: chicken
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Gene
100426588 | IL18R1
Type: gene
Organism: macaque, rhesus
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Gene
101732855 | il18r1
Type: gene
Organism: frog, western clawed
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Gene
301365 | Il18r1
Type: gene
Organism: rat
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Gene
611438 | IL18R1
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:105383 | Il18r1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
18714006 | J:138949
First Author: Yu Q
Year: 2008
Journal: J Immunol
Title: Transcription factor-dependent chromatin remodeling of Il18r1 during Th1 and Th2 differentiation.
Volume: 181
Issue: 5
Pages: 3346-52
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Publication
26893476 | J:231696
First Author: Markowitz GJ
Year: 2016
Journal: Cancer Res
Title: Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes.
Volume: 76
Issue: 8
Pages: 2394-405
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Publication
26638073 | J:227990
First Author: Nowarski R
Year: 2015
Journal: Cell
Title: Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.
Volume: 163
Issue: 6
Pages: 1444-56
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Publication
26656097 | J:249916
 
First Author: Pazos P
Year: 2015
Journal: Sci Rep
Title: Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice.
Volume: 5
Pages: 17977
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Publication
17380127 | J:122523
First Author: Yu Q
Year: 2007
Journal: EMBO J
Title: Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation.
Volume: 26
Issue: 8
Pages: 2052-60
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Protein Coding Gene
MGP_CAROLIEiJ_G0014081 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0015968 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0015952 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0015907 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0015906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0015739 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_105383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016359 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0015711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0015812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0015814 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0015882 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0015834 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016406 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015103 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027326 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0014885 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
27062602 | J:246483
First Author: Holmkvist P
Year: 2016
Journal: Eur J Immunol
Title: IL-18Rα-deficient CD4(+) T cells induce intestinal inflammation in the CD45RB(hi) transfer model of colitis despite impaired innate responsiveness.
Volume: 46
Issue: 6
Pages: 1371-82
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Publication
31914650 | J:299530
First Author: Huang Y
Year: 2020
Journal: FASEB J
Title: IL-18R-dependent and independent pathways account for IL-18-enhanced antitumor ability of CAR-T cells.
Volume: 34
Issue: 1
Pages: 1768-1782
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Publication
23670974 | J:208960
First Author: Lindegaard B
Year: 2013
Journal: Diabetes
Title: Interleukin-18 activates skeletal muscle AMPK and reduces weight gain and insulin resistance in mice.
Volume: 62
Issue: 9
Pages: 3064-74
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Publication
29261164 | J:273881
 
First Author: Nozaki Y
Year: 2017
Journal: Int J Mol Sci
Title: Lipopolysaccharide-Induced Acute Kidney Injury Is Dependent on an IL-18 Receptor Signaling Pathway.
Volume: 18
Issue: 12
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Publication
16127163 | J:100679
First Author: Shannon P
Year: 2005
Journal: Am J Pathol
Title: Pathological and molecular progression of astrocytomas in a GFAP:12 V-Ha-Ras mouse astrocytoma model.
Volume: 167
Issue: 3
Pages: 859-67
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Publication
27147667 | J:231812
First Author: Francesconi W
Year: 2016
Journal: J Neurosci
Title: The Proinflammatory Cytokine Interleukin 18 Regulates Feeding by Acting on the Bed Nucleus of the Stria Terminalis.
Volume: 36
Issue: 18
Pages: 5170-80
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Publication
25329004 | J:218021
First Author: Yano T
Year: 2015
Journal: Lab Invest
Title: The pathological role of IL-18Rα in renal ischemia/reperfusion injury.
Volume: 95
Issue: 1
Pages: 78-91
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Publication
31861496 | J:295409
 
First Author: Nozaki Y
Year: 2019
Journal: Cells
Title: Inhibition of the IL-18 Receptor Signaling Pathway Ameliorates Disease in a Murine Model of Rheumatoid Arthritis.
Volume: 9
Issue: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3838209
Assay Type: RT-PCR
Annotation Date: 2009-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3820119
Stage: TS19
Assay Id: MGI:3838325
Age: embryonic day 11.5
Specimen Label: AGM +
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3838209
Assay Type: RT-PCR
Annotation Date: 2009-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3820119
Stage: TS19
Assay Id: MGI:3838334
Age: embryonic day 11.5
Specimen Label: AGM +/+ +
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3838209
Assay Type: RT-PCR
Annotation Date: 2009-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3820119
Stage: TS19
Assay Id: MGI:3838334
Age: embryonic day 11.5
Specimen Label: AGM -/- +
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4416775
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825573
Age: embryonic day 14.5
Image: euxassay_012379_10
Specimen Label: euxassay_012379_10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4416775
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825573
Age: embryonic day 14.5
Image: euxassay_012379_11
Specimen Label: euxassay_012379_11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4416775
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825573
Age: embryonic day 14.5
Image: euxassay_012379_13
Specimen Label: euxassay_012379_13
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4416775
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4825573
Age: embryonic day 14.5
Image: euxassay_012379_14
Specimen Label: euxassay_012379_14
Detected: true
Specimen Num: 4
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Publication
8626725 | J:31466
First Author: Parnet P
Year: 1996
Journal: J Biol Chem
Title: IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP.
Volume: 271
Issue: 8
Pages: 3967-70
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Publication
20833839 | J:164277
First Author: Blumberg H
Year: 2010
Journal: J Immunol
Title: IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.
Volume: 185
Issue: 7
Pages: 4354-62
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Publication
23478406 | J:197539
First Author: Cohen TS
Year: 2013
Journal: J Clin Invest
Title: Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia.
Volume: 123
Issue: 4
Pages: 1630-7
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Publication
19223481 | J:148206
First Author: Haring JS
Year: 2009
Journal: Infect Immun
Title: Interleukin-18-related genes are induced during the contraction phase but do not play major roles in regulating the dynamics or function of the T-cell response to Listeria monocytogenes infection.
Volume: 77
Issue: 5
Pages: 1894-903
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Publication
25729923 | J:231648
First Author: Nold-Petry CA
Year: 2015
Journal: Nat Immunol
Title: IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction.
Volume: 16
Issue: 4
Pages: 354-65
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Publication
30316805 | J:318530
 
First Author: Wu Z
Year: 2019
Journal: Exp Hematol
Title: Interleukin-18 plays a dispensable role in murine and likely also human bone marrow failure.
Volume: 69
Pages: 54-64.e2
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Publication
17237446 | J:143631
First Author: Kang MJ
Year: 2007
Journal: J Immunol
Title: IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.
Volume: 178
Issue: 3
Pages: 1948-59
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Publication
21715688 | J:179180
First Author: Ghose P
Year: 2011
Journal: J Immunol
Title: The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria.
Volume: 187
Issue: 3
Pages: 1333-46
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Publication
17075045 | J:117139
First Author: Lewis EC
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Responses of IL-18- and IL-18 receptor-deficient pancreatic islets with convergence of positive and negative signals for the IL-18 receptor.
Volume: 103
Issue: 45
Pages: 16852-7
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Publication
29681594 | J:273944
First Author: Hayakawa T
Year: 2017
Journal: Okajimas Folia Anat Jpn
Title: Postnatal changes of interleukin-18 receptor immunoreactivity in neurons of the retrosplenial cortex in wild-type and interleukin-18 knock out mice.
Volume: 94
Issue: 3
Pages: 93-99
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Publication
17400610 | J:122662
First Author: Li W
Year: 2007
Journal: J Leukoc Biol
Title: Protection of CD8+ T cells from activation-induced cell death by IL-18.
Volume: 82
Issue: 1
Pages: 142-51
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Publication
28373090 | J:252253
 
First Author: Kuwahara-Otani S
Year: 2017
Journal: Neurosci Lett
Title: Interleukin-18 and its receptor are expressed in gonadotropin-releasing hormone neurons of mouse and rat forebrain.
Volume: 650
Pages: 33-37
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Publication
31366712 | J:278695
First Author: Zhang S
Year: 2019
Journal: J Immunol
Title: The Transcription Factor PLZF Is Necessary for the Development and Function of Mouse Basophils.
Volume: 203
Issue: 5
Pages: 1230-1241
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Publication
18768833 | J:139113
First Author: Rahman AH
Year: 2008
Journal: J Immunol
Title: MyD88 plays a critical T cell-intrinsic role in supporting CD8 T cell expansion during acute lymphocytic choriomeningitis virus infection.
Volume: 181
Issue: 6
Pages: 3804-10
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Publication
28283665 | J:243368
First Author: Brandstadter JD
Year: 2017
Journal: J Leukoc Biol
Title: IL-18-dependent NKG2D ligand upregulation on accessory cells is mediated by the PI3K/GSK-3 pathway.
Volume: 101
Issue: 6
Pages: 1317-1323
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Publication
22419664 | J:189352
First Author: Coulouarn C
Year: 2012
Journal: Cancer Res
Title: Hepatocyte-stellate cell cross-talk in the liver engenders a permissive inflammatory microenvironment that drives progression in hepatocellular carcinoma.
Volume: 72
Issue: 10
Pages: 2533-42
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Publication
23300570 | J:195732
First Author: Hwang I
Year: 2012
Journal: PLoS One
Title: Activation mechanisms of natural killer cells during influenza virus infection.
Volume: 7
Issue: 12
Pages: e51858
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Publication
36766797 | J:337148
 
First Author: Nasiri E
Year: 2023
Journal: Cells
Title: IL18 Receptor Signaling Inhibits Intratumoral CD8(+) T-Cell Migration in a Murine Pancreatic Cancer Model.
Volume: 12
Issue: 3
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Publication
37081148 | J:337722
First Author: Park MD
Year: 2023
Journal: Nat Immunol
Title: TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer.
Volume: 24
Issue: 5
Pages: 792-801
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Publication
32687059 | J:313536
   
First Author: Peligero-Cruz C
Year: 2020
Journal: Elife
Title: IL18 signaling promotes homing of mature Tregs into the thymus.
Volume: 9
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Publication
25780034 | J:337030
First Author: Gandhapudi SK
Year: 2015
Journal: J Immunol
Title: IL-18 acts in synergy with IL-7 to promote ex vivo expansion of T lymphoid progenitor cells.
Volume: 194
Issue: 8
Pages: 3820-8
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Publication
17475863 | J:146116
First Author: Srinivasan A
Year: 2007
Journal: J Immunol
Title: Innate immune activation of CD4 T cells in salmonella-infected mice is dependent on IL-18.
Volume: 178
Issue: 10
Pages: 6342-9
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Publication
21270393 | J:169397
First Author: Wan Y
Year: 2011
Journal: J Immunol
Title: The dual functions of IL-1 receptor-associated kinase 2 in TLR9-mediated IFN and proinflammatory cytokine production.
Volume: 186
Issue: 5
Pages: 3006-14
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Publication
28747343 | J:242759
First Author: Savage AK
Year: 2017
Journal: J Immunol
Title: The Development of Steady-State Activation Hubs between Adult LTi ILC3s and Primed Macrophages in Small Intestine.
Volume: 199
Issue: 5
Pages: 1912-1922
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Publication
37071533 | J:335544
First Author: Lim YS
Year: 2023
Journal: Cell Rep
Title: NK cell-derived extracellular granzyme B drives epithelial ulceration during HSV-2 genital infection.
Volume: 42
Issue: 4
Pages: 112410
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Publication
35381213 | J:325490
First Author: Fang D
Year: 2022
Journal: Immunity
Title: Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation.
Volume: 55
Issue: 4
Pages: 639-655.e7
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Publication
16818787 | J:135038
First Author: Scheibner KA
Year: 2006
Journal: J Immunol
Title: Hyaluronan fragments act as an endogenous danger signal by engaging TLR2.
Volume: 177
Issue: 2
Pages: 1272-81
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Publication
32581358 | J:291344
First Author: Zhou T
Year: 2020
Journal: Nature
Title: IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy.
Volume: 583
Issue: 7817
Pages: 609-614
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Publication
16732281 | J:109552
First Author: Netea MG
Year: 2006
Journal: Nat Med
Title: Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance.
Volume: 12
Issue: 6
Pages: 650-6
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Publication
21980291 | J:183336
First Author: Ingram JT
Year: 2011
Journal: PLoS Pathog
Title: Exhausted CD8 T cells downregulate the IL-18 receptor and become unresponsive to inflammatory cytokines and bacterial co-infections.
Volume: 7
Issue: 9
Pages: e1002273
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Publication
10227969 | J:70298
First Author: Hoshino K
Year: 1999
Journal: J Immunol
Title: Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor.
Volume: 162
Issue: 9
Pages: 5041-4
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Publication
24531812 | J:210478
First Author: Toldo S
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Interleukin-18 mediates interleukin-1-induced cardiac dysfunction.
Volume: 306
Issue: 7
Pages: H1025-31
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Publication
24610009 | J:210246
First Author: Wilson NS
Year: 2014
Journal: J Immunol
Title: Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.
Volume: 192
Issue: 7
Pages: 3259-68
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Publication
27794001 | J:303440
First Author: Desbien AL
Year: 2016
Journal: J Immunol
Title: IL-18 and Subcapsular Lymph Node Macrophages are Essential for Enhanced B Cell Responses with TLR4 Agonist Adjuvants.
Volume: 197
Issue: 11
Pages: 4351-4359
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Publication
21270336 | J:169092
First Author: Ellebedy AH
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59.
Volume: 108
Issue: 7
Pages: 2927-32
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Publication
25367751 | J:222315
First Author: Desbien AL
Year: 2015
Journal: Eur J Immunol
Title: Squalene emulsion potentiates the adjuvant activity of the TLR4 agonist, GLA, via inflammatory caspases, IL-18, and IFN-γ.
Volume: 45
Issue: 2
Pages: 407-17
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Publication
19592492 | J:156368
First Author: Nold-Petry CA
Year: 2009
Journal: J Biol Chem
Title: Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling.
Volume: 284
Issue: 38
Pages: 25900-11
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Publication
34093543 | J:341833
 
First Author: Khan AUH
Year: 2021
Journal: Front Immunol
Title: Expression of Nutrient Transporters on NK Cells During Murine Cytomegalovirus Infection Is MyD88-Dependent.
Volume: 12
Pages: 654225
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Publication
26099046 | J:224865
First Author: Wang J
Year: 2015
Journal: Nat Med
Title: Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.
Volume: 21
Issue: 7
Pages: 820-6
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Publication
34493727 | J:337117
First Author: Kim SH
Year: 2021
Journal: Nat Commun
Title: Adoptive immunotherapy with transient anti-CD4 treatment enhances anti-tumor response by increasing IL-18Rα(hi) CD8(+) T cells.
Volume: 12
Issue: 1
Pages: 5314
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Publication
27668799 | J:259343
First Author: Koay HF
Year: 2016
Journal: Nat Immunol
Title: A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage.
Volume: 17
Issue: 11
Pages: 1300-1311
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Publication
24439266 | J:209373
First Author: Schenten D
Year: 2014
Journal: Immunity
Title: Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells.
Volume: 40
Issue: 1
Pages: 78-90
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Publication
16906165 | J:112650
First Author: Gutcher I
Year: 2006
Journal: Nat Immunol
Title: Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation.
Volume: 7
Issue: 9
Pages: 946-53
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Publication
31923399 | J:291950
First Author: Jarret A
Year: 2020
Journal: Cell
Title: Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.
Volume: 180
Issue: 1
Pages: 50-63.e12
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Publication
26367276 | J:245813
First Author: Nanjappa SG
Year: 2015
Journal: PLoS Pathog
Title: Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia.
Volume: 11
Issue: 9
Pages: e1005161
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17617611 | J:149392
First Author: Fremond CM
Year: 2007
Journal: J Immunol
Title: IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection.
Volume: 179
Issue: 2
Pages: 1178-89
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21930764 | J:178488
First Author: Miura K
Year: 2011
Journal: Infect Immun
Title: Ehrlichia chaffeensis induces monocyte inflammatory responses through MyD88, ERK, and NF-κB but not through TRIF, interleukin-1 receptor 1 (IL-1R1)/IL-18R1, or toll-like receptors.
Volume: 79
Issue: 12
Pages: 4947-56
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First Author: Oliveira AC
Year: 2017
Journal: Elife
Title: Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.
Volume: 6
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First Author: Clark SE
Year: 2018
Journal: Cell Rep
Title: A Batf3/Nlrp3/IL-18 Axis Promotes Natural Killer Cell IL-10 Production during Listeria monocytogenes Infection.
Volume: 23
Issue: 9
Pages: 2582-2594
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30127003 | J:265540
First Author: Tzeng TC
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.
Volume: 115
Issue: 36
Pages: 9002-9007
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First Author: Zalinger ZB
Year: 2017
Journal: J Neurovirol
Title: Role of the inflammasome-related cytokines Il-1 and Il-18 during infection with murine coronavirus.
Volume: 23
Issue: 6
Pages: 845-854
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First Author: Wu C
Year: 2019
Journal: Immunity
Title: Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis.
Volume: 50
Issue: 6
Pages: 1401-1411.e4
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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