|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 217 for Il27

<< First    < Previous  |  Next >    Last >>
0.039s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GO Term
Publication
First Author: Pflanz S
Year: 2002
Journal: Immunity
Title: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.
Volume: 16
Issue: 6
Pages: 779-90
Publication
First Author: Dibra D
Year: 2016
Journal: Clin Cancer Res
Title: Lack of Immunomodulatory Interleukin-27 Enhances Oncogenic Properties of Mutant p53 In Vivo.
Volume: 22
Issue: 15
Pages: 3876-83
Publication
First Author: Liao J
Year: 2014
Journal: PLoS One
Title: An image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouse.
Volume: 9
Issue: 9
Pages: e108777
Publication  
First Author: Andrews C
Year: 2023
Journal: Front Immunol
Title: IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium.
Volume: 14
Pages: 1021824
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Shimizu M
Year: 2006
Journal: J Immunol
Title: Antiangiogenic and antitumor activities of IL-27.
Volume: 176
Issue: 12
Pages: 7317-24
Publication
First Author: Owaki T
Year: 2006
Journal: J Immunol
Title: IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways.
Volume: 177
Issue: 11
Pages: 7579-87
Publication
First Author: Fitzgerald DC
Year: 2007
Journal: J Immunol
Title: Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis.
Volume: 179
Issue: 5
Pages: 3268-75
Publication
First Author: Sorrentino C
Year: 2018
Journal: Cancer Res
Title: Interleukin-30/IL27p28 Shapes Prostate Cancer Stem-like Cell Behavior and Is Critical for Tumor Onset and Metastasization.
Volume: 78
Issue: 10
Pages: 2654-2668
Publication
First Author: Diveu C
Year: 2009
Journal: J Immunol
Title: IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells.
Volume: 182
Issue: 9
Pages: 5748-56
Publication  
First Author: Li P
Year: 2024
Journal: Int Immunopharmacol
Title: Deletion of IL-27p28 induces CD8 T cell immunity against colorectal tumorigenesis.
Volume: 128
Pages: 111464
Publication  
First Author: Tang H
Year: 2016
Journal: Sci Rep
Title: Thymic DCs derived IL-27 regulates the final maturation of CD4(+) SP thymocytes.
Volume: 6
Pages: 30448
Publication
First Author: Wei J
Year: 2013
Journal: J Immunol
Title: Critical role of dendritic cell-derived IL-27 in antitumor immunity through regulating the recruitment and activation of NK and NKT cells.
Volume: 191
Issue: 1
Pages: 500-8
Publication
First Author: Yoshimoto T
Year: 2008
Journal: J Immunol
Title: Antiproliferative activity of IL-27 on melanoma.
Volume: 180
Issue: 10
Pages: 6527-35
Publication
First Author: Yoshimoto T
Year: 2004
Journal: J Immunol
Title: Induction of IgG2a class switching in B cells by IL-27.
Volume: 173
Issue: 4
Pages: 2479-85
Publication
First Author: Goldberg R
Year: 2004
Journal: J Immunol
Title: Suppression of ongoing experimental autoimmune encephalomyelitis by neutralizing the function of the p28 subunit of IL-27.
Volume: 173
Issue: 10
Pages: 6465-71
Publication
First Author: Yoshimoto T
Year: 2007
Journal: J Immunol
Title: IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.
Volume: 179
Issue: 7
Pages: 4415-23
Publication
First Author: Tormo AJ
Year: 2013
Journal: J Immunol
Title: A polyglutamic acid motif confers IL-27 hydroxyapatite and bone-binding properties.
Volume: 190
Issue: 6
Pages: 2931-7
Publication
First Author: Zhao X
Year: 2017
Journal: Nat Commun
Title: Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage.
Volume: 8
Issue: 1
Pages: 602
Publication
First Author: Kilgore AM
Year: 2020
Journal: J Immunol
Title: cDC1 IL-27p28 Production Predicts Vaccine-Elicited CD8+ T Cell Memory and Protective Immunity.
Volume: 204
Issue: 3
Pages: 510-517
Publication
First Author: Kilgore AM
Year: 2018
Journal: Immunohorizons
Title: IL-27p28 Production by XCR1+ Dendritic Cells and Monocytes Effectively Predicts Adjuvant-Elicited CD8+ T Cell Responses.
Volume: 2
Issue: 1
Pages: 1-11
Publication
First Author: Visperas A
Year: 2014
Journal: Mucosal Immunol
Title: IL-27, targeting antigen-presenting cells, promotes Th17 differentiation and colitis in mice.
Volume: 7
Issue: 3
Pages: 625-33
Publication
First Author: van Leeuwen MA
Year: 2017
Journal: Mucosal Immunol
Title: Macrophage-mediated gliadin degradation and concomitant IL-27 production drive IL-10- and IFN-γ-secreting Tr1-like-cell differentiation in a murine model for gluten tolerance.
Volume: 10
Issue: 3
Pages: 635-649
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:4999636
Age: postnatal
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:4999636
Age: embryonic day 4.5
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160396
Stage: TS06
Assay Id: MGI:4999636
Age: embryonic day 4.5
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160426
Stage: TS06
Assay Id: MGI:4999636
Age: embryonic day 4.5
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:4999636
Age: embryonic day 5.5
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160398
Stage: TS08
Assay Id: MGI:4999636
Age: embryonic day 5.5
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160428
Stage: TS08
Assay Id: MGI:4999636
Age: embryonic day 5.5
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3527028
Stage: TS28
Assay Id: MGI:4999636
Age: embryonic day 6.5
Specimen Label: 7
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:4999636
Age: postnatal
Specimen Label: 9
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:4999636
Age: embryonic day 4.5
Specimen Label: 10
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160396
Stage: TS06
Assay Id: MGI:4999636
Age: embryonic day 4.5
Specimen Label: 10
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160426
Stage: TS06
Assay Id: MGI:4999636
Age: embryonic day 4.5
Specimen Label: 10
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526928
Stage: TS28
Assay Id: MGI:4999636
Age: embryonic day 5.5
Specimen Label: 12
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160398
Stage: TS08
Assay Id: MGI:4999636
Age: embryonic day 5.5
Specimen Label: 12
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160428
Stage: TS08
Assay Id: MGI:4999636
Age: embryonic day 5.5
Specimen Label: 12
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:4999631
Assay Type: RT-PCR
Annotation Date: 2011-05-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3527028
Stage: TS28
Assay Id: MGI:4999636
Age: embryonic day 6.5
Specimen Label: 14
Detected: false
Specimen Num: 14
Publication
First Author: Morishima N
Year: 2005
Journal: J Immunol
Title: Augmentation of effector CD8+ T cell generation with enhanced granzyme B expression by IL-27.
Volume: 175
Issue: 3
Pages: 1686-93
Publication
First Author: Wirtz S
Year: 2006
Journal: J Exp Med
Title: Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27.
Volume: 203
Issue: 8
Pages: 1875-81
Publication
First Author: Villegas-Mendez A
Year: 2013
Journal: PLoS Pathog
Title: IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals.
Volume: 9
Issue: 4
Pages: e1003293
Publication
First Author: Vasconcellos R
Year: 2011
Journal: J Immunol
Title: IL-12p35 subunit contributes to autoimmunity by limiting IL-27-driven regulatory responses.
Volume: 187
Issue: 6
Pages: 3402-12
Publication
First Author: Natividad KD
Year: 2013
Journal: PLoS One
Title: Interleukin-27 signaling promotes immunity against endogenously arising murine tumors.
Volume: 8
Issue: 3
Pages: e57469
Publication
First Author: Cao Y
Year: 2008
Journal: J Immunol
Title: IL-27 induces a Th1 immune response and susceptibility to experimental arthritis.
Volume: 180
Issue: 2
Pages: 922-30
Publication
First Author: Pearl JE
Year: 2004
Journal: J Immunol
Title: IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice.
Volume: 173
Issue: 12
Pages: 7490-6
Publication
First Author: Wu M
Year: 2021
Journal: Nat Commun
Title: WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression.
Volume: 12
Issue: 1
Pages: 3500
Publication
First Author: Anderson CF
Year: 2009
Journal: J Immunol
Title: IL-27 regulates IL-10 and IL-17 from CD4+ cells in nonhealing Leishmania major infection.
Volume: 183
Issue: 7
Pages: 4619-27
Publication
First Author: Villarino AV
Year: 2005
Journal: J Immunol
Title: Positive and negative regulation of the IL-27 receptor during lymphoid cell activation.
Volume: 174
Issue: 12
Pages: 7684-91
Publication  
First Author: Povroznik JM
Year: 2023
Journal: Front Immunol
Title: Interleukin-27-dependent transcriptome signatures during neonatal sepsis.
Volume: 14
Pages: 1124140
Publication
First Author: Sato Y
Year: 2014
Journal: Biochem Biophys Res Commun
Title: IL-27 affects helper T cell responses via regulation of PGE2 production by macrophages.
Volume: 451
Issue: 2
Pages: 215-21
Publication
First Author: Kanai K
Year: 2018
Journal: J Immunol
Title: Murine γ-Herpesvirus 68 Induces Severe Lung Inflammation in IL-27-Deficient Mice with Liver Dysfunction Preventable by Oral Neomycin.
Volume: 200
Issue: 8
Pages: 2703-2713
Publication
First Author: Troy AE
Year: 2009
Journal: J Immunol
Title: IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis.
Volume: 183
Issue: 3
Pages: 2037-44
Publication
First Author: Liu G
Year: 2015
Journal: PLoS Pathog
Title: IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ.
Volume: 11
Issue: 7
Pages: e1005065
Publication
First Author: Nortey A
Year: 2022
Journal: J Neuroinflammation
Title: The cytokine IL-27 reduces inflammation and protects photoreceptors in a mouse model of retinal degeneration.
Volume: 19
Issue: 1
Pages: 216
Publication
First Author: Tato CM
Year: 2012
Journal: PLoS One
Title: The myeloid receptor PILRβ mediates the balance of inflammatory responses through regulation of IL-27 production.
Volume: 7
Issue: 3
Pages: e31680
Publication
First Author: Batten M
Year: 2008
Journal: J Immunol
Title: Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells.
Volume: 180
Issue: 5
Pages: 2752-6
Publication
First Author: Rousseau F
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants.
Volume: 107
Issue: 45
Pages: 19420-5
Publication
First Author: Fitzgerald DC
Year: 2013
Journal: J Immunol
Title: Independent and interdependent immunoregulatory effects of IL-27, IFN-β, and IL-10 in the suppression of human Th17 cells and murine experimental autoimmune encephalomyelitis.
Volume: 190
Issue: 7
Pages: 3225-34
Publication
First Author: Zha X
Year: 2021
Journal: J Immunol
Title: IL-27/IL-27R Mediates Protective Immunity against Chlamydial Infection by Suppressing Excessive Th17 Responses and Reducing Neutrophil Inflammation.
Volume: 206
Issue: 9
Pages: 2160-2169
Publication
First Author: Neufert C
Year: 2007
Journal: Eur J Immunol
Title: IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1.
Volume: 37
Issue: 7
Pages: 1809-16
Publication
First Author: Shimizu M
Year: 2013
Journal: Immunobiology
Title: IL-27 promotes nitric oxide production induced by LPS through STAT1, NF-κB and MAPKs.
Volume: 218
Issue: 4
Pages: 628-34
Publication
First Author: Kamiya S
Year: 2004
Journal: J Immunol
Title: An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells.
Volume: 173
Issue: 6
Pages: 3871-7
Publication
First Author: Owaki T
Year: 2008
Journal: J Immunol
Title: STAT3 is indispensable to IL-27-mediated cell proliferation but not to IL-27-induced Th1 differentiation and suppression of proinflammatory cytokine production.
Volume: 180
Issue: 5
Pages: 2903-11
Publication
First Author: Zhang S
Year: 2013
Journal: Hepatology
Title: High susceptibility to liver injury in IL-27 p28 conditional knockout mice involves intrinsic interferon-γ dysregulation of CD4+ T cells.
Volume: 57
Issue: 4
Pages: 1620-31
Publication
First Author: Zheng T
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Protein kinase p38α signaling in dendritic cells regulates colon inflammation and tumorigenesis.
Volume: 115
Issue: 52
Pages: E12313-E12322
Publication
First Author: Lee MH
Year: 2019
Journal: J Leukoc Biol
Title: The cytokine network type I IFN-IL-27-IL-10 is augmented in murine and human lupus.
Volume: 106
Issue: 4
Pages: 967-975
Publication
First Author: Hedrich CM
Year: 2010
Journal: Mol Immunol
Title: Dynamic DNA methylation patterns across the mouse and human IL10 genes during CD4+ T cell activation; influence of IL-27.
Volume: 48
Issue: 1-3
Pages: 73-81
Publication
First Author: Pyle CJ
Year: 2017
Journal: PLoS Pathog
Title: Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.
Volume: 13
Issue: 9
Pages: e1006640
Publication
First Author: Nguyen TH
Year: 2018
Journal: J Immunol
Title: Identification of IFN-γ and IL-27 as Critical Regulators of Respiratory Syncytial Virus-Induced Exacerbation of Allergic Airways Disease in a Mouse Model.
Volume: 200
Issue: 1
Pages: 237-247
Publication
First Author: Yoshimura T
Year: 2006
Journal: J Immunol
Title: Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism.
Volume: 177
Issue: 8
Pages: 5377-85
Publication
First Author: Kochetkova I
Year: 2014
Journal: J Immunol
Title: Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27.
Volume: 192
Issue: 2
Pages: 804-16
Publication
First Author: Sasaguri T
Year: 2018
Journal: Sci Rep
Title: Interleukin-27 controls basal pain threshold in physiological and pathological conditions.
Volume: 8
Issue: 1
Pages: 11022