Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Peng SY |
Year: |
2018 |
Journal: |
MGI Direct Data Submission |
Title: |
Direct data submission for Il2rg allele. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Direct data submission for Il2rg allele |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
449
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Maykel J |
Year: |
2014 |
Journal: |
Dig Dis Sci |
Title: |
NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer. |
Volume: |
59 |
Issue: |
6 |
Pages: |
1169-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruggero K |
Year: |
2016 |
Journal: |
Leukemia |
Title: |
LMO2 and IL2RG synergize in thymocytes to mimic the evolution of SCID-X1 gene therapy-associated T-cell leukaemia. |
Volume: |
30 |
Issue: |
9 |
Pages: |
1959-62 |
|
•
•
•
•
•
|
Allele |
Name: |
interleukin 2 receptor, gamma chain; endonuclease-mediated mutation 3, Cathleen Lutz |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
interleukin 2 receptor, gamma chain; endonuclease-mediated mutation 8, Cathy Lutz |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Pike-Overzet K |
Year: |
2006 |
Journal: |
Nature |
Title: |
Gene therapy: is IL2RG oncogenic in T-cell development? |
Volume: |
443 |
Issue: |
7109 |
Pages: |
E5; discussion E6-7 |
|
•
•
•
•
•
|
Allele |
Name: |
interleukin 2 receptor, gamma chain; endonuclease-mediated mutation 1, Cathy Lutz |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Publication |
First Author: |
Pollock K |
Year: |
2023 |
Journal: |
Sci Rep |
Title: |
An immune deficient mouse model for mucopolysaccharidosis IIIA (Sanfilippo syndrome). |
Volume: |
13 |
Issue: |
1 |
Pages: |
18439 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wunderlich M |
Year: |
2018 |
Journal: |
PLoS One |
Title: |
Improved multilineage human hematopoietic reconstitution and function in NSGS mice. |
Volume: |
13 |
Issue: |
12 |
Pages: |
e0209034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lewis BW |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
The Innate Lymphoid System Is a Critical Player in the Manifestation of Mucoinflammatory Airway Disease in Mice. |
Volume: |
205 |
Issue: |
6 |
Pages: |
1695-1708 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arpke RW |
Year: |
2013 |
Journal: |
Stem Cells |
Title: |
A new immuno-, dystrophin-deficient model, the NSG-mdx(4Cv) mouse, provides evidence for functional improvement following allogeneic satellite cell transplantation. |
Volume: |
31 |
Issue: |
8 |
Pages: |
1611-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Merzoug LB |
Year: |
2014 |
Journal: |
Eur J Immunol |
Title: |
Conditional ablation of NKp46+ cells using a novel Ncr1(greenCre) mouse strain: NK cells are essential for protection against pulmonary B16 metastases. |
Volume: |
44 |
Issue: |
11 |
Pages: |
3380-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Charles River |
Year: |
2017 |
Journal: |
Scientific info. sheet (http://www.criver.com/files/pdfs/rms/ncg/ncg-mouse-scientific--sheet.aspx) |
Title: |
NOD CRISPR Prkdcil2r Gamma (NCG) Triple-Immunodeficient Mouse Model |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng M |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development. |
Volume: |
182 |
Issue: |
3 |
Pages: |
1460-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2008 |
Journal: |
Biol Reprod |
Title: |
Dynamic changes occur in patterns of endometrial EFNB2/EPHB4 expression during the period of spiral arterial modification in mice. |
Volume: |
79 |
Issue: |
3 |
Pages: |
450-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bobbala D |
Year: |
2012 |
Journal: |
Diabetologia |
Title: |
Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse. |
Volume: |
55 |
Issue: |
11 |
Pages: |
3010-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Covassin L |
Year: |
2013 |
Journal: |
Clin Exp Immunol |
Title: |
Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells. |
Volume: |
174 |
Issue: |
3 |
Pages: |
372-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
DiSanto JP |
Year: |
1994 |
Journal: |
Eur J Immunol |
Title: |
The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus. |
Volume: |
24 |
Issue: |
12 |
Pages: |
3014-8 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumaki S |
Year: |
1993 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Cloning of the mouse interleukin 2 receptor gamma chain: demonstration of functional differences between the mouse and human receptors. |
Volume: |
193 |
Issue: |
1 |
Pages: |
356-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobayashi N |
Year: |
1993 |
Journal: |
Gene |
Title: |
Cloning and sequencing of the cDNA encoding a mouse IL-2 receptor gamma. |
Volume: |
130 |
Issue: |
2 |
Pages: |
303-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
DiSanto JP |
Year: |
1995 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain. |
Volume: |
92 |
Issue: |
2 |
Pages: |
377-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
GarcÃa-Ojeda ME |
Year: |
2013 |
Journal: |
Blood |
Title: |
GATA-3 promotes T-cell specification by repressing B-cell potential in pro-T cells in mice. |
Volume: |
121 |
Issue: |
10 |
Pages: |
1749-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
von Köckritz-Blickwede M |
Year: |
2008 |
Journal: |
Am J Pathol |
Title: |
Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model. |
Volume: |
173 |
Issue: |
6 |
Pages: |
1657-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
De Riva A |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Noncognate interaction with MHC class II molecules is essential for maintenance of T cell metabolism to establish optimal memory CD4 T cell function. |
Volume: |
178 |
Issue: |
9 |
Pages: |
5488-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Greenblatt MB |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Graft versus host disease in the bone marrow, liver and thymus humanized mouse model. |
Volume: |
7 |
Issue: |
9 |
Pages: |
e44664 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blom B |
Year: |
1997 |
|
Title: |
The role of the common gamma chain of the IL-2, IL-4, IL-7 and IL-15 receptors in development of lymphocytes, constitutive of Bcl-2 does not rescue the developmental defects in gamma common-defiecent mice |
|
|
Pages: |
3-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao X |
Year: |
1995 |
Journal: |
Immunity |
Title: |
Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. |
Volume: |
2 |
Issue: |
3 |
Pages: |
223-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tolar J |
Year: |
2007 |
Journal: |
Exp Hematol |
Title: |
The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia. |
Volume: |
35 |
Issue: |
4 |
Pages: |
682-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li L |
Year: |
2012 |
Journal: |
Cancer Cell |
Title: |
Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib. |
Volume: |
21 |
Issue: |
2 |
Pages: |
266-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nolte T |
Year: |
2013 |
Journal: |
Dis Model Mech |
Title: |
Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγ(null) mice engrafted with human peripheral blood mononuclear cells. |
Volume: |
6 |
Issue: |
1 |
Pages: |
125-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saito A |
Year: |
2016 |
Journal: |
J Virol |
Title: |
Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo. |
Volume: |
90 |
Issue: |
15 |
Pages: |
6918-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Czuczman NM |
Year: |
2016 |
Journal: |
Blood |
Title: |
Pevonedistat, a NEDD8-activating enzyme inhibitor, is active in mantle cell lymphoma and enhances rituximab activity in vivo. |
Volume: |
127 |
Issue: |
9 |
Pages: |
1128-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Billerbeck E |
Year: |
2011 |
Journal: |
Blood |
Title: |
Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2Rγ(null) humanized mice. |
Volume: |
117 |
Issue: |
11 |
Pages: |
3076-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakajima H |
Year: |
1997 |
Journal: |
J Exp Med |
Title: |
The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis. |
Volume: |
185 |
Issue: |
2 |
Pages: |
189-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fiorito V |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation. |
Volume: |
35 |
Issue: |
11 |
Pages: |
109252 |
|
•
•
•
•
•
|
Publication |
First Author: |
Unzu C |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Innate functions of immunoglobulin M lessen liver gene transfer with helper-dependent adenovirus. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e85432 |
|
•
•
•
•
•
|
Publication |
First Author: |
Merck E |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Ly49D engagement on T lymphocytes induces TCR-independent activation and CD8 effector functions that control tumor growth. |
Volume: |
182 |
Issue: |
1 |
Pages: |
183-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wunderlich M |
Year: |
2014 |
Journal: |
Blood |
Title: |
OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues. |
Volume: |
123 |
Issue: |
24 |
Pages: |
e134-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bryce PJ |
Year: |
2016 |
Journal: |
J Allergy Clin Immunol |
Title: |
Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis. |
Volume: |
138 |
Issue: |
3 |
Pages: |
769-779 |
|
•
•
•
•
•
|
Publication |
First Author: |
Santoni de Sio FR |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Ectopic FOXP3 Expression Preserves Primitive Features Of Human Hematopoietic Stem Cells While Impairing Functional T Cell Differentiation. |
Volume: |
7 |
Issue: |
1 |
Pages: |
15820 |
|
•
•
•
•
•
|
Publication |
First Author: |
Torreggiani E |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Preosteocytes/osteocytes have the potential to dedifferentiate becoming a source of osteoblasts. |
Volume: |
8 |
Issue: |
9 |
Pages: |
e75204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borel F |
Year: |
2017 |
Journal: |
Mol Ther |
Title: |
Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency. |
Volume: |
25 |
Issue: |
11 |
Pages: |
2477-2489 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aspord C |
Year: |
2014 |
Journal: |
J Invest Dermatol |
Title: |
Imiquimod inhibits melanoma development by promoting pDC cytotoxic functions and impeding tumor vascularization. |
Volume: |
134 |
Issue: |
10 |
Pages: |
2551-2561 |
|
•
•
•
•
•
|
Publication |
First Author: |
Long BR |
Year: |
2012 |
Journal: |
J Virol |
Title: |
Alpha interferon and HIV infection cause activation of human T cells in NSG-BLT mice. |
Volume: |
86 |
Issue: |
6 |
Pages: |
3327-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nozad Charoudeh H |
Year: |
2010 |
Journal: |
Blood |
Title: |
Identification of an NK/T cell-restricted progenitor in adult bone marrow contributing to bone marrow- and thymic-dependent NK cells. |
Volume: |
116 |
Issue: |
2 |
Pages: |
183-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanno T |
Year: |
2014 |
Journal: |
Blood |
Title: |
Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells. |
Volume: |
123 |
Issue: |
5 |
Pages: |
725-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Civenni G |
Year: |
2011 |
Journal: |
Cancer Res |
Title: |
Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth. |
Volume: |
71 |
Issue: |
8 |
Pages: |
3098-109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karst AM |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Modeling high-grade serous ovarian carcinogenesis from the fallopian tube. |
Volume: |
108 |
Issue: |
18 |
Pages: |
7547-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Turaj AH |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Augmentation of CD134 (OX40)-dependent NK anti-tumour activity is dependent on antibody cross-linking. |
Volume: |
8 |
Issue: |
1 |
Pages: |
2278 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu X |
Year: |
2010 |
Journal: |
Behav Brain Res |
Title: |
The effects of IL2Rgamma knockout on depression and contextual memory. |
Volume: |
213 |
Issue: |
2 |
Pages: |
319-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu J |
Year: |
2018 |
Journal: |
Stem Cells Transl Med |
Title: |
Generation of Transplantable Retinal Photoreceptors from a Current Good Manufacturing Practice-Manufactured Human Induced Pluripotent Stem Cell Line. |
Volume: |
7 |
Issue: |
2 |
Pages: |
210-219 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohbo K |
Year: |
1996 |
Journal: |
Blood |
Title: |
Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor gamma chain. |
Volume: |
87 |
Issue: |
3 |
Pages: |
956-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu M |
Year: |
2007 |
Journal: |
Cell Stem Cell |
Title: |
Imaging hematopoietic precursor division in real time. |
Volume: |
1 |
Issue: |
5 |
Pages: |
541-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Horino S |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Gene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vector. |
Volume: |
8 |
Issue: |
8 |
Pages: |
e71594 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ikebe M |
Year: |
1997 |
Journal: |
Int J Exp Pathol |
Title: |
Lymphohaematopoietic abnormalities and systemic lymphoproliferative disorder in interleukin-2 receptor gamma chain-deficient mice. |
Volume: |
78 |
Issue: |
3 |
Pages: |
133-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyazaki S |
Year: |
2002 |
Journal: |
Am J Reprod Immunol |
Title: |
Interleukin 2 receptor gamma chain (gamma(c)) knockout mice show less regularity in estrous cycle but achieve normal pregnancy without fetal compromise. |
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