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Search results 1 to 100 out of 108 for Il3ra

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
3563 | IL3RA
Type: gene
Organism: human
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Gene
106995138 | IL3RA
Type: gene
Organism: macaque, rhesus
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Gene
246144 | Il3ra
Type: gene
Organism: rat
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Gene
609293 | IL3RA
Type: gene
Organism: dog, domestic
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Gene
100299249 | IL3RA
Type: gene
Organism: cattle
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Protein Coding Gene
MGI:96553 | Il3ra
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
27257215 | J:232998
First Author: Agger K
Year: 2016
Journal: Genes Dev
Title: Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.
Volume: 30
Issue: 11
Pages: 1278-88
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Protein Coding Gene
MGP_CAROLIEiJ_G0018962 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021009 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020957 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020934 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020960 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020744 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96553 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021393 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020266 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020710 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020909 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020841 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021426 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020018 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020324 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029976 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019838 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
7889941 | J:23971
First Author: Ichihara M
Year: 1995
Journal: EMBO J
Title: Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene.
Volume: 14
Issue: 5
Pages: 939-50
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Publication
7727767 | J:24918
First Author: Hara T
Year: 1995
Journal: Blood
Title: Interleukin-3 (IL-3) poor-responsive inbred mouse strains carry the identical deletion of a branch point in the IL-3 receptor alpha subunit gene.
Volume: 85
Issue: 9
Pages: 2331-6
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Publication
8605333 | J:32585
First Author: Leslie KB
Year: 1996
Journal: Blood
Title: Genetic basis of hypo-responsiveness of A/J mice to interleukin-3.
Volume: 87
Issue: 8
Pages: 3186-94
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GXD Expression
GXD Expression
   
Probe: MGI:6119437
Assay Type: RT-PCR
Annotation Date: 2018-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6119439
Age: embryonic day 9.5
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6119437
Assay Type: RT-PCR
Annotation Date: 2018-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6119439
Age: embryonic day 9.5
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6119437
Assay Type: RT-PCR
Annotation Date: 2018-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6119439
Age: embryonic day 9.5
Image: 3
Specimen Label: -/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
       
Probe: MGI:2651895
Assay Type: RT-PCR
Annotation Date: 2003-03-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:2651913
Age: postnatal adult
Specimen Label: Unfr BM
Specimen Num: 1
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GXD Expression
GXD Expression
       
Probe: MGI:2651895
Assay Type: RT-PCR
Annotation Date: 2003-03-21
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1608514
Stage: TS14
Assay Id: MGI:2651913
Age: embryonic day 9.0
Specimen Label: Unfr YS
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2680348
Assay Type: RT-PCR
Annotation Date: 2003-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:2680408
Age: embryonic day 3.5
Specimen Label: blast.
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6416139
Assay Type: RT-PCR
Annotation Date: 2020-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3597319
Stage: TS19
Assay Id: MGI:6416144
Age: embryonic day 11.5
Specimen Label: AoM
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6416139
Assay Type: RT-PCR
Annotation Date: 2020-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1620419
Stage: TS19
Assay Id: MGI:6416144
Age: embryonic day 11.5
Specimen Label: AoM
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6416139
Assay Type: RT-PCR
Annotation Date: 2020-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636719
Stage: TS19
Assay Id: MGI:6416144
Age: embryonic day 11.5
Specimen Label: UGR
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6416139
Assay Type: RT-PCR
Annotation Date: 2020-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608519
Stage: TS19
Assay Id: MGI:6416144
Age: embryonic day 11.5
Specimen Label: YS
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6416139
Assay Type: RT-PCR
Annotation Date: 2020-05-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3603419
Stage: TS19
Assay Id: MGI:6416144
Age: embryonic day 11.5
Specimen Label: V/U
Detected: true
Specimen Num: 4
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Publication
- | J:670
First Author: Hara T
Year: 1992
Journal: FASEB J
Title: cDNA cloning of a mouse IL-3 receptor alpha subunit
Volume: 6
Issue: 5
Pages: A1606 (Abstr.)
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Publication
- | J:16982
     
First Author: Miyajima A
Year: 1990
Title: Cloning of a cDNA encoding a murine interleukin-3 receptor
Pages: 149-154
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Publication
37541770 | J:341590
First Author: Ullrich KA
Year: 2023
Journal: Gut
Title: IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells.
Volume: 72
Issue: 11
Pages: 2081-2094
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Publication
7522247 | J:20422
First Author: Mueller DL
Year: 1994
Journal: J Immunol
Title: Subset of CD4+ T cell clones expressing IL-3 receptor alpha-chains uses IL-3 as a cofactor in autocrine growth.
Volume: 153
Issue: 7
Pages: 3014-27
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Publication
8806599 | J:35287
First Author: Morikawa Y
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Expression of IL-3 receptor in testis.
Volume: 226
Issue: 1
Pages: 107-12
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Publication
1582416 | J:957
First Author: Hara T
Year: 1992
Journal: EMBO J
Title: Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3).
Volume: 11
Issue: 5
Pages: 1875-84
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Publication
8903724 | J:30840
First Author: Ellison JW
Year: 1996
Journal: Mamm Genome
Title: Rapid evolution of human pseudoautosomal genes and their mouse homologs.
Volume: 7
Issue: 1
Pages: 25-30
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Publication
19109256 | J:147898
First Author: Chen J
Year: 2009
Journal: J Biol Chem
Title: A new isoform of interleukin-3 receptor {alpha} with novel differentiation activity and high affinity binding mode.
Volume: 284
Issue: 9
Pages: 5763-73
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Publication
18495327 | J:141681
First Author: Jing X
Year: 2008
Journal: Exp Hematol
Title: E3 ligase FLRF (Rnf41) regulates differentiation of hematopoietic progenitors by governing steady-state levels of cytokine and retinoic acid receptors.
Volume: 36
Issue: 9
Pages: 1110-20
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Publication
16890157 | J:119282
First Author: Robin C
Year: 2006
Journal: Dev Cell
Title: An unexpected role for IL-3 in the embryonic development of hematopoietic stem cells.
Volume: 11
Issue: 2
Pages: 171-80
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Publication
9531584 | J:47462
First Author: Gainsford T
Year: 1998
Journal: Blood
Title: Cytokine production and function in c-mpl-deficient mice: no physiologic role for interleukin-3 in residual megakaryocyte and platelet production.
Volume: 91
Issue: 8
Pages: 2745-52
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Publication
34262178 | J:335093
First Author: McAlpine CS
Year: 2021
Journal: Nature
Title: Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease.
Volume: 595
Issue: 7869
Pages: 701-706
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Publication
22875843 | J:189836
First Author: Hidano S
Year: 2012
Journal: Int Immunol
Title: SLP-76 is required for high-affinity IgE receptor- and IL-3 receptor-mediated activation of basophils.
Volume: 24
Issue: 11
Pages: 719-27
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Publication
7858255 | J:23120
First Author: Miyajima I
Year: 1995
Journal: Blood
Title: The murine interleukin-3 receptor alpha subunit gene: chromosomal localization, genomic structure, and promoter function.
Volume: 85
Issue: 5
Pages: 1246-53
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Publication
16261417 | J:102636
First Author: Peters LL
Year: 2005
Journal: Mamm Genome
Title: Quantitative trait loci for baseline white blood cell count, platelet count, and mean platelet volume.
Volume: 16
Issue: 10
Pages: 749-63
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Publication
27748374 | J:241037
First Author: Clarke M
Year: 2017
Journal: Leukemia
Title: Transcriptional regulation of SPROUTY2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3.
Volume: 31
Issue: 4
Pages: 957-966
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Publication
12093914 | J:77725
First Author: Regan CP
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects.
Volume: 99
Issue: 14
Pages: 9248-53
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Publication
16897342 | J:111669
First Author: Sollars VE
Year: 2006
Journal: Mamm Genome
Title: Analysis of expansion of myeloid progenitors in mice to identify leukemic susceptibility genes.
Volume: 17
Issue: 8
Pages: 808-21
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Publication
9324354 | J:43157
First Author: Yoder MC
Year: 1997
Journal: Immunity
Title: Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac.
Volume: 7
Issue: 3
Pages: 335-44
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Publication
8499630 | J:12563
First Author: McClanahan T
Year: 1993
Journal: Blood
Title: Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells.
Volume: 81
Issue: 11
Pages: 2903-15
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Publication
23754746 | J:204566
First Author: Gendrel AV
Year: 2013
Journal: Mol Cell Biol
Title: Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes.
Volume: 33
Issue: 16
Pages: 3150-65
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Il3ra<em1Smoc> | MGI:7290513
Name: interleukin 3 receptor, alpha chain; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428979 | C57BL/6JSmoc-Il3ra<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
25043189 | -
First Author: Broughton SE
Year: 2014
Journal: Cell Rep
Title: Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody.
Volume: 8
Issue: 2
Pages: 410-9
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Protein Domain
IPR040907 | IL3Ra_N
Type: Domain
Description: Interleukin-3 (IL-3) is an activated T cell product that bridges innate and adaptive immunity and contributes to several immunopathologies. Structure of IL-3 receptor alpha chain (IL3Ra) in complex with the anti-leukemia antibody CSL362 reveals that the N-terminal domain (NTD), a domain also present in the granulocyte-macrophage colony-stimulating factor (GM-CSF), contains the CSL362 binding epitope. Furthermore, NTD of IL3Ra adopts a typical fibronectin type III (FnIII) fold [].
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Publication
37160117 | J:355198
First Author: Kiss MG
Year: 2023
Journal: Immunity
Title: Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis.
Volume: 56
Issue: 7
Pages: 1502-1514.e8
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Publication
38331257 | J:345928
 
First Author: Li ZA
Year: 2024
Journal: Virus Res
Title: Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response.
Volume: 342
Pages: 199335
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Protein Domain
IPR003532 | Short_hematopoietin_rcpt_2_CS
Type: Conserved_site
Description: A number of receptors for lymphokines, hematopoietic growth factors and growth hormone-related molecules have been found to share a common binding domain. These receptors are designated as hematopoietin receptors []and the corresponding ligands as hematopoietins. Further, hematopoietins have been subdivided into two major structural groups: large (long) and small (short) hematopoietins.One subset of individual receptor chains that are part of receptor complexes for small hematopoietins contain common structural elements: an extracellular receptor domain that contains an immunoglobulin-like region at the N-terminal end; a transmembrane domain; and a short cytoplasmic domain. They define a structural subgroup containing the following chains:Granulocyte/macrophage colony stimulating factor receptor alpha (GMCSFRA)Interleukin-3 receptor alpha chain (IL3RA)Interleukin-5 receptor alpha chain (IL5RA)Interleukin-13 receptor alpha-1 chain (IL13RA1)Interleukin-13 receptor alpha-2 chain (IL13RA2)GMCSFRA, IL3RA or IL5RA chains of this subgroup bind to their cognate cytokines: GM-CSF, IL-3 and IL-5, with a common beta chain, KH97/AIC2B []. Either IL13RA1 chain or IL13RA2 chain form the IL13R complex together with IL4RA chain. IL-4 can compete with IL-13 to bind to either IL13R form [].
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Publication
8552669 | J:30615
First Author: Hilton DJ
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor.
Volume: 93
Issue: 1
Pages: 497-501
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Publication
1913811 | -
First Author: Nicola NA
Year: 1991
Journal: Cell
Title: Subunit promiscuity among hemopoietic growth factor receptors.
Volume: 67
Issue: 1
Pages: 1-4
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Protein
A0A286YE20
Organism: Mus musculus/domesticus
Length: 196  
Fragment?: false
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Protein
A9P557
Organism: Mus musculus/domesticus
Length: 363  
Fragment?: false
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Protein
A0A286YE23
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Protein
A9P558
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: false
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Protein
Q00941
Organism: Mus musculus/domesticus
Length: 388  
Fragment?: false
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Protein
B2RWT6
Organism: Mus musculus/domesticus
Length: 388  
Fragment?: false
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Protein
P26952
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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•
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Protein
P21183
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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