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Search results 1 to 100 out of 3232 for Il4

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
3565 | IL4
Type: gene
Organism: human
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Gene
416330 | IL4
Type: gene
Organism: chicken
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Gene
100188894 | il4
Type: gene
Organism: zebrafish
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Gene
574281 | IL4
Type: gene
Organism: macaque, rhesus
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Gene
100135068 | il4
Type: gene
Organism: frog, western clawed
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Gene
280824 | IL4
Type: gene
Organism: cattle
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Gene
key_38338 | IL4
Type: gene
Organism: sheep
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Gene
key_31738 | IL4
Type: gene
Organism: pig, domestic
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Gene
287287 | Il4
Type: gene
Organism: rat
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Gene
403785 | IL4
Type: gene
Organism: dog, domestic
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Gene
449565 | IL4
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:96556 | Il4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21131966 | J:167446
First Author: Tanaka S
Year: 2011
Journal: Nat Immunol
Title: The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells.
Volume: 12
Issue: 1
Pages: 77-85
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GXD Expression
GXD Expression
   
Probe: MGI:3056624
Assay Type: RT-PCR
Annotation Date: 2004-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3505777
Age: postnatal week 9.5
Image: 4
Specimen Label: Th2 Il4 9.5W WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3056624
Assay Type: RT-PCR
Annotation Date: 2004-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3505777
Age: postnatal week 9.5
Image: 4
Specimen Label: Th2 Il4 9.5W KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3056624
Assay Type: RT-PCR
Annotation Date: 2004-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3505777
Age: postnatal month 9
Image: 4
Specimen Label: Th2 Il4 9M WT
Detected: true
Specimen Num: 3
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Publication
27920023 | J:318403
First Author: Shirota H
Year: 2017
Journal: Cancer Immunol Res
Title: IL4 from T Follicular Helper Cells Downregulates Antitumor Immunity.
Volume: 5
Issue: 1
Pages: 61-71
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Publication
31160756 | J:315642
First Author: Wang L
Year: 2020
Journal: Cell Mol Immunol
Title: Spatial distribution of IL4 controls iNKT cell-DC crosstalk in tumors.
Volume: 17
Issue: 5
Pages: 496-506
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Publication
19561615 | J:151652
First Author: Okamoto M
Year: 2009
Journal: Nat Immunol
Title: Mina, an Il4 repressor, controls T helper type 2 bias.
Volume: 10
Issue: 8
Pages: 872-9
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Publication
24947041 | J:213715
First Author: Venmar KT
Year: 2014
Journal: Cancer Res
Title: IL4 receptor ILR4α regulates metastatic colonization by mammary tumors through multiple signaling pathways.
Volume: 74
Issue: 16
Pages: 4329-40
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Publication
15516924 | J:94039
First Author: Ansel KM
Year: 2004
Journal: Nat Immunol
Title: Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity.
Volume: 5
Issue: 12
Pages: 1251-9
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Publication
22326582 | J:181313
First Author: Vijayanand P
Year: 2012
Journal: Immunity
Title: Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V.
Volume: 36
Issue: 2
Pages: 175-87
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Publication
29297752 | J:281835
First Author: Xia F
Year: 2018
Journal: Autophagy
Title: IL4 (interleukin 4) induces autophagy in B cells leading to exacerbated asthma.
Volume: 14
Issue: 3
Pages: 450-464
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Publication
17195845 | J:117861
First Author: Djuretic IM
Year: 2007
Journal: Nat Immunol
Title: Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells.
Volume: 8
Issue: 2
Pages: 145-53
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Publication
17908791 | J:129048
First Author: Yagi R
Year: 2007
Journal: Mol Cell Biol
Title: Regulation of the Il4 gene is independently controlled by proximal and distal 3' enhancers in mast cells and basophils.
Volume: 27
Issue: 23
Pages: 8087-97
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Publication
17646405 | J:125953
First Author: Naoe Y
Year: 2007
Journal: J Exp Med
Title: Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer.
Volume: 204
Issue: 8
Pages: 1749-55
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QTL
MGI:3590288 | Tsiq3
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:3590286 | Tsiq1
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:3590287 | Tsiq2
Type: QTL
Organism: mouse, laboratory
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Publication
22365664 | J:181626
First Author: Harada Y
Year: 2012
Journal: Immunity
Title: The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells.
Volume: 36
Issue: 2
Pages: 188-200
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Publication
23837489 | J:231562
First Author: Kobayashi T
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: IL-1 family cytokines drive Th2 and Th17 cells to innocuous airborne antigens.
Volume: 49
Issue: 6
Pages: 989-98
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Publication
10069422 | J:53107
First Author: Ho IC
Year: 1999
Journal: Int Immunol
Title: Marking IL-4-producing cells by knock-in of the IL-4 gene.
Volume: 11
Issue: 2
Pages: 243-7
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Publication
15034018 | J:88681
First Author: Kolodsick JE
Year: 2004
Journal: J Immunol
Title: Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts.
Volume: 172
Issue: 7
Pages: 4068-76
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Publication
10679097 | J:60609
First Author: Fallon PG
Year: 2000
Journal: J Immunol
Title: Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent.
Volume: 164
Issue: 5
Pages: 2585-91
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Publication
16226507 | J:113279
First Author: Mohrs K
Year: 2005
Journal: Immunity
Title: A two-step process for cytokine production revealed by IL-4 dual-reporter mice.
Volume: 23
Issue: 4
Pages: 419-29
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Publication
11441125 | J:106687
First Author: Inoue Y
Year: 2001
Journal: J Immunol
Title: Failure to induce neonatal tolerance in mice that lack both IL-4 and IL-13 but not in those that lack IL-4 alone.
Volume: 167
Issue: 2
Pages: 1125-8
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Publication
18250447 | J:131994
First Author: Castilow EM
Year: 2008
Journal: J Immunol
Title: IL-13 is required for eosinophil entry into the lung during respiratory syncytial virus vaccine-enhanced disease.
Volume: 180
Issue: 4
Pages: 2376-84
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Publication
15741272 | J:97167
First Author: Bian K
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Helminth regulation of host IL-4Ralpha/Stat6 signaling: mechanism underlying NOS-2 inhibition by Trichinella spiralis.
Volume: 102
Issue: 11
Pages: 3936-41
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Publication
18410989 | J:139377
First Author: Tawara I
Year: 2008
Journal: Exp Hematol
Title: Combined Th2 cytokine deficiency in donor T cells aggravates experimental acute graft-vs-host disease.
Volume: 36
Issue: 8
Pages: 988-96
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Publication
28765368 | J:243776
First Author: Vicetti Miguel RD
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: IL-4-secreting eosinophils promote endometrial stromal cell proliferation and prevent Chlamydia-induced upper genital tract damage.
Volume: 114
Issue: 33
Pages: E6892-E6901
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Publication
26410628 | J:233776
First Author: Chen CY
Year: 2015
Journal: Immunity
Title: Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy.
Volume: 43
Issue: 4
Pages: 788-802
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Publication
27117406 | J:235391
First Author: Schleicher U
Year: 2016
Journal: Cell Rep
Title: TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Volume: 15
Issue: 5
Pages: 1062-1075
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Publication
8755560 | J:34313
First Author: Rankin JA
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity.
Volume: 93
Issue: 15
Pages: 7821-5
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Publication
17982031 | J:153871
First Author: Khodoun M
Year: 2007
Journal: J Immunol
Title: Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responses.
Volume: 179
Issue: 10
Pages: 6429-38
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Publication
28302646 | J:241865
First Author: Diny NL
Year: 2017
Journal: J Exp Med
Title: Eosinophil-derived IL-4 drives progression of myocarditis to inflammatory dilated cardiomyopathy.
Volume: 214
Issue: 4
Pages: 943-957
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Publication
16277637 | J:105853
First Author: Fujita K
Year: 2006
Journal: Immunol Cell Biol
Title: Role for IL-4 nonproducing NKT cells in CC-chemokine ligand 2-induced Th2 cell generation.
Volume: 84
Issue: 1
Pages: 44-50
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Publication
8584936 | J:31486
First Author: Noben-Trauth N
Year: 1996
Journal: Science
Title: Susceptibility to Leishmania major infection in interleukin-4-deficient mice.
Volume: 271
Issue: 5251
Pages: 987-90
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Publication
8906833 | J:37196
First Author: Metwali A
Year: 1996
Journal: J Immunol
Title: The granulomatous response in murine Schistosomiasis mansoni does not switch to Th1 in IL-4-deficient C57BL/6 mice.
Volume: 157
Issue: 10
Pages: 4546-53
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Publication
17586699 | J:128039
First Author: Johnson JR
Year: 2007
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes.
Volume: 293
Issue: 3
Pages: L730-9
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Publication
11069076 | J:65232
First Author: Alexander J
Year: 2000
Journal: Eur J Immunol
Title: Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis.
Volume: 30
Issue: 10
Pages: 2935-43
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Publication
14971043 | J:87666
First Author: Hernandez-Pando R
Year: 2004
Journal: Eur J Immunol
Title: Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis.
Volume: 34
Issue: 1
Pages: 174-83
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Publication
28315756 | J:250295
 
First Author: Wachholz S
Year: 2017
Journal: Behav Brain Res
Title: Interleukin-4 is a participant in the regulation of depressive-like behavior.
Volume: 326
Pages: 165-172
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Publication
16002690 | J:100700
First Author: Mangashetti LS
Year: 2005
Journal: J Immunol
Title: IL-4 inhibits bone-resorbing activity of mature osteoclasts by affecting NF-kappa B and Ca2+ signaling.
Volume: 175
Issue: 2
Pages: 917-25
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Publication
29615715 | J:263098
First Author: Laudenbach M
Year: 2018
Journal: Sci Rep
Title: Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose.
Volume: 8
Issue: 1
Pages: 5508
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Publication
16027141 | J:99968
First Author: Hiraoka S
Year: 2005
Journal: Int Immunol
Title: B7.2-Ig fusion proteins enhance IL-4-dependent differentiation of tumor-sensitized CD8+ cytotoxic T lymphocyte precursors.
Volume: 17
Issue: 8
Pages: 1071-9
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Publication
10049944 | J:53801
First Author: Schüler T
Year: 1999
Journal: J Exp Med
Title: T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice.
Volume: 189
Issue: 5
Pages: 803-10
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Publication
10569763 | J:58540
First Author: Heinzel FP
Year: 1999
Journal: Infect Immun
Title: Interleukin-4-independent acceleration of cutaneous leishmaniasis in susceptible BALB/c mice following treatment with anti-CTLA4 antibody.
Volume: 67
Issue: 12
Pages: 6454-60
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Publication
16423063 | J:106772
First Author: Maroof A
Year: 2006
Journal: Immunology
Title: Interleukin-4 can induce interleukin-4 production in dendritic cells.
Volume: 117
Issue: 2
Pages: 271-9
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Publication
10556817 | J:115123
First Author: Kropf P
Year: 1999
Journal: Eur J Immunol
Title: Expression of Th2 cytokines and the stable Th2 marker ST2L in the absence of IL-4 during Leishmania major infection.
Volume: 29
Issue: 11
Pages: 3621-8
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Publication
10727445 | J:61145
First Author: Herrick CA
Year: 2000
Journal: J Clin Invest
Title: Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4.
Volume: 105
Issue: 6
Pages: 765-75
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Publication
19587017 | J:151702
First Author: Moore ML
Year: 2009
Journal: J Immunol
Title: STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection.
Volume: 183
Issue: 3
Pages: 2016-26
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Publication
20418876 | J:160618
First Author: Perona-Wright G
Year: 2010
Journal: Nat Immunol
Title: Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node.
Volume: 11
Issue: 6
Pages: 520-6
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Publication
11520464 | J:75415
First Author: Mohrs M
Year: 2001
Journal: Immunity
Title: Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter.
Volume: 15
Issue: 2
Pages: 303-11
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Publication
29613835 | J:276669
First Author: Mbanefo EC
Year: 2018
Journal: FASEB J
Title: Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis.
Volume: 32
Issue: 8
Pages: 4408-4419
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Publication
16210636 | J:119109
First Author: Mohrs K
Year: 2005
Journal: J Immunol
Title: Systemic dissemination and persistence of Th2 and type 2 cells in response to infection with a strictly enteric nematode parasite.
Volume: 175
Issue: 8
Pages: 5306-13
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Publication
18188454 | J:131191
First Author: Katzman SD
Year: 2008
Journal: J Clin Invest
Title: Pathogen-imposed skewing of mouse chemokine and cytokine expression at the infected tissue site.
Volume: 118
Issue: 2
Pages: 801-11
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Publication
23207180 | J:321085
First Author: Bao L
Year: 2013
Journal: Cytokine
Title: IL-4 up-regulates epidermal chemotactic, angiogenic, and pro-inflammatory genes and down-regulates antimicrobial genes in vivo and in vitro: relevant in the pathogenesis of atopic dermatitis.
Volume: 61
Issue: 2
Pages: 419-25
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Publication
12376365 | J:107354
First Author: Izbicki G
Year: 2002
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Bleomycin-induced lung fibrosis in IL-4-overexpressing and knockout mice.
Volume: 283
Issue: 5
Pages: L1110-6
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Publication
21484783 | J:177311
First Author: Kitajima M
Year: 2011
Journal: Eur J Immunol
Title: TSLP enhances the function of helper type 2 cells.
Volume: 41
Issue: 7
Pages: 1862-71
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Publication
16126843 | J:100501
First Author: Morimoto Y
Year: 2005
Journal: J Leukoc Biol
Title: Induction of surface CCR4 and its functionality in mouse Th2 cells is regulated differently during Th2 development.
Volume: 78
Issue: 3
Pages: 753-61
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Publication
27457412 | J:246642
First Author: Tripathi P
Year: 2016
Journal: Eur J Immunol
Title: IL-4 and IL-15 promotion of virtual memory CD8+ T cells is determined by genetic background.
Volume: 46
Issue: 10
Pages: 2333-2339
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Publication
9686617 | J:48882
First Author: Hogan SP
Year: 1998
Journal: J Immunol
Title: A novel T cell-regulated mechanism modulating allergen-induced airways hyperreactivity in BALB/c mice independently of IL-4 and IL-5.
Volume: 161
Issue: 3
Pages: 1501-9
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Publication
19221040 | J:148423
First Author: Pillai AB
Year: 2009
Journal: Blood
Title: Host natural killer T cells induce an interleukin-4-dependent expansion of donor CD4+CD25+Foxp3+ T regulatory cells that protects against graft-versus-host disease.
Volume: 113
Issue: 18
Pages: 4458-67
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Publication
25751266 | J:228337
First Author: Sakala IG
Year: 2015
Journal: PLoS One
Title: Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection.
Volume: 10
Issue: 3
Pages: e0118685
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Publication
11705956 | J:73137
First Author: Spencer L
Year: 2001
Journal: Infect Immun
Title: Interleukin-4 receptor-Stat6 signaling in murine infections with a tissue-dwelling nematode parasite.
Volume: 69
Issue: 12
Pages: 7743-52
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Publication
12709397 | J:84825
First Author: Yokota N
Year: 2003
Journal: Am J Physiol Renal Physiol
Title: Contrasting roles for STAT4 and STAT6 signal transduction pathways in murine renal ischemia-reperfusion injury.
Volume: 285
Issue: 2
Pages: F319-25
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Publication
12218156 | J:120443
First Author: Finnegan A
Year: 2002
Journal: J Immunol
Title: IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms.
Volume: 169
Issue: 6
Pages: 3345-52
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Publication
9492006 | J:110429
First Author: Urban JF Jr
Year: 1998
Journal: Immunity
Title: IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.
Volume: 8
Issue: 2
Pages: 255-64
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Publication
10586035 | J:58976
First Author: Brewer JM
Year: 1999
Journal: J Immunol
Title: Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signaling.
Volume: 163
Issue: 12
Pages: 6448-54
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Publication
24723460 | J:328378
First Author: Proctor WR
Year: 2014
Journal: Hepatology
Title: Thymic stromal lymphopoietin and interleukin-4 mediate the pathogenesis of halothane-induced liver injury in mice.
Volume: 60
Issue: 5
Pages: 1741-52
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Publication
9064329 | J:35236
First Author: Kopf M
Year: 1996
Journal: J Exp Med
Title: IL-4-deficient Balb/c mice resist infection with Leishmania major.
Volume: 184
Issue: 3
Pages: 1127-36
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Publication
11034365 | J:118728
First Author: Sasaki H
Year: 2000
Journal: J Immunol
Title: IL-10, but not IL-4, suppresses infection-stimulated bone resorption in vivo.
Volume: 165
Issue: 7
Pages: 3626-30
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Publication
23255589 | J:195232
First Author: Abston ED
Year: 2013
Journal: Am J Physiol Regul Integr Comp Physiol
Title: TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: role for IL-4.
Volume: 304
Issue: 4
Pages: R267-77
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Publication
11163865 | J:66151
First Author: Noben-Trauth N
Year: 2000
Journal: Immunol Lett
Title: Susceptibility to Leishmania major infection in the absence of IL-4.
Volume: 75
Issue: 1
Pages: 41-4
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Publication
16556895 | J:135755
First Author: Ghassabeh GH
Year: 2006
Journal: Blood
Title: Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions.
Volume: 108
Issue: 2
Pages: 575-83
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Publication
19692641 | J:152324
First Author: Hepworth MR
Year: 2009
Journal: J Immunol
Title: Disruption of Th2 immunity results in a gender-specific expansion of IL-13 producing accessory NK cells during helminth infection.
Volume: 183
Issue: 6
Pages: 3906-14
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Publication
28202615 | J:252702
First Author: Brombacher TM
Year: 2017
Journal: J Immunol
Title: IL-13-Mediated Regulation of Learning and Memory.
Volume: 198
Issue: 7
Pages: 2681-2688
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Publication
15544617 | J:94577
First Author: Nagayama Y
Year: 2004
Journal: Clin Exp Immunol
Title: TSH receptor-adenovirus-induced Graves' hyperthyroidism is attenuated in both interferon-gamma and interleukin-4 knockout mice; implications for the Th1/Th2 paradigm.
Volume: 138
Issue: 3
Pages: 417-22
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Publication
18097046 | J:130916
First Author: Petritus PM
Year: 2008
Journal: J Immunol
Title: Suppression of lethal Plasmodium yoelii malaria following protective immunization requires antibody-, IL-4-, and IFN-gamma-dependent responses induced by vaccination and/or challenge infection.
Volume: 180
Issue: 1
Pages: 444-53
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Publication
11891315 | J:75471
First Author: Kodera T
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts.
Volume: 99
Issue: 6
Pages: 3800-5
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