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Search results 1 to 100 out of 385 for Ilk

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Type Details Score
Gene
3611 | ILK
Type: gene
Organism: human
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Gene
476836 | ILK
Type: gene
Organism: dog, domestic
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Gene
540207 | ILK
Type: gene
Organism: cattle
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Gene
374018 | ILK
Type: gene
Organism: chicken
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Gene
393543 | ilk
Type: gene
Organism: zebrafish
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Gene
709944 | ILK
Type: gene
Organism: macaque, rhesus
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Gene
100145644 | ilk
Type: gene
Organism: frog, western clawed
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Gene
170922 | Ilk
Type: gene
Organism: rat
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Gene
748941 | ILK
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1195267 | Ilk
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
80895 | ILKAP
Type: gene
Organism: human
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GXD Expression
GXD Expression
     
Probe: MGI:3054003
Assay Type: Immunohistochemistry
Annotation Date: 2004-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360354
Stage: TS04
Assay Id: MGI:3054008
Age: embryonic day 3.5
Specimen Label: 2A, Ilk -/-
Detected: false
Specimen Num: 2
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Publication
23715557 | J:218656
First Author: Serrano I
Year: 2013
Journal: Cardiovasc Res
Title: Ilk conditional deletion in adult animals increases cyclic GMP-dependent vasorelaxation.
Volume: 99
Issue: 3
Pages: 535-44
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Publication
24371086 | J:266746
First Author: Rudkouskaya A
Year: 2014
Journal: Mol Biol Cell
Title: ILK modulates epithelial polarity and matrix formation in hair follicles.
Volume: 25
Issue: 5
Pages: 620-32
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Publication
20164118 | J:175876
First Author: Hortelano S
Year: 2010
Journal: Cardiovasc Res
Title: ILK mediates LPS-induced vascular adhesion receptor expression and subsequent leucocyte trans-endothelial migration.
Volume: 86
Issue: 2
Pages: 283-92
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Publication
16951252 | J:112174
First Author: White DE
Year: 2006
Journal: Genes Dev
Title: Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure.
Volume: 20
Issue: 17
Pages: 2355-60
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Publication
11304546 | J:70132
First Author: Nikolopoulos SN
Year: 2001
Journal: J Biol Chem
Title: Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions.
Volume: 276
Issue: 26
Pages: 23499-505
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Publication
26837762 | J:231630
First Author: Krenn PW
Year: 2016
Journal: Cancer Res
Title: ILK Induction in Lymphoid Organs by a TNFα-NF-κB-Regulated Pathway Promotes the Development of Chronic Lymphocytic Leukemia.
Volume: 76
Issue: 8
Pages: 2186-96
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Publication
27760768 | J:284357
First Author: Mamuya FA
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: ILK and cytoskeletal architecture: an important determinant of AQP2 recycling and subsequent entry into the exocytotic pathway.
Volume: 311
Issue: 6
Pages: F1346-F1357
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Publication
29638158 | J:280117
First Author: Gong X
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Expression of ILK in renal stroma is essential for multiple aspects of renal development.
Volume: 315
Issue: 2
Pages: F374-F385
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Publication
24319095 | J:315330
First Author: Dai J
Year: 2014
Journal: Circ Heart Fail
Title: Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout mice.
Volume: 7
Issue: 1
Pages: 184-93
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Publication
19435803 | J:150585
First Author: Stanchi F
Year: 2009
Journal: J Cell Sci
Title: Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation.
Volume: 122
Issue: Pt 11
Pages: 1800-11
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Publication
25669897 | J:244756
 
First Author: Morris EJ
Year: 2015
Journal: Sci Rep
Title: Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum.
Volume: 5
Pages: 8389
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Publication
23658024 | J:199658
First Author: Moik D
Year: 2013
Journal: J Biol Chem
Title: Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice.
Volume: 288
Issue: 26
Pages: 18863-71
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Publication
24095779 | J:206620
First Author: El-Hoss J
Year: 2014
Journal: Gene
Title: Inactivation of the integrin-linked kinase (ILK) in osteoblasts increases mineralization.
Volume: 533
Issue: 1
Pages: 246-52
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Gene
64538 | Ilkap
Type: gene
Organism: rat
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Gene
486179 | ILKAP
Type: gene
Organism: dog, domestic
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Gene
746056 | ILKAP
Type: gene
Organism: chimpanzee
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Gene
514223 | ILKAP
Type: gene
Organism: cattle
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Gene
424850 | ILKAP
Type: gene
Organism: chicken
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Gene
706334 | ILKAP
Type: gene
Organism: macaque, rhesus
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Gene
595059 | ilkap
Type: gene
Organism: frog, western clawed
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Publication
20564195 | J:197593
First Author: Dossa T
Year: 2010
Journal: J Cell Biochem
Title: Osteoclast-specific inactivation of the integrin-linked kinase (ILK) inhibits bone resorption.
Volume: 110
Issue: 4
Pages: 960-7
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Publication
9366252 | J:43595
First Author: Li F
Year: 1997
Journal: Biochim Biophys Acta
Title: Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase.
Volume: 1358
Issue: 3
Pages: 215-20
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Publication
29787769 | J:268141
 
First Author: Xu XF
Year: 2018
Journal: Brain Res
Title: Elevating Integrin-linked Kinase expression has rescued hippocampal neurogenesis and memory deficits in an AD animal model.
Volume: 1695
Pages: 65-77
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Publication
21593206 | J:172933
First Author: Nakrieko KA
Year: 2011
Journal: Mol Biol Cell
Title: Targeted inactivation of integrin-linked kinase in hair follicle stem cells reveals an important modulatory role in skin repair after injury.
Volume: 22
Issue: 14
Pages: 2532-40
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Publication
25268583 | J:218617
First Author: Vi L
Year: 2015
Journal: J Invest Dermatol
Title: Modulation of type II TGF-β receptor degradation by integrin-linked kinase.
Volume: 135
Issue: 3
Pages: 885-894
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Publication
20980390 | J:182911
First Author: Blumbach K
Year: 2010
Journal: J Cell Sci
Title: Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGFβ1 levels and RhoA activity.
Volume: 123
Issue: Pt 22
Pages: 3872-83
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Publication
16421303 | J:104504
First Author: Mills J
Year: 2006
Journal: J Neurosci
Title: Critical role of integrin-linked kinase in granule cell precursor proliferation and cerebellar development.
Volume: 26
Issue: 3
Pages: 830-40
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Publication
26967476 | J:231068
First Author: Sayedyahossein S
Year: 2016
Journal: J Invest Dermatol
Title: Integrin-Linked Kinase Is Indispensable for Keratinocyte Differentiation and Epidermal Barrier Function.
Volume: 136
Issue: 2
Pages: 425-35
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Publication
16611717 | J:129244
First Author: El-Aouni C
Year: 2006
Journal: J Am Soc Nephrol
Title: Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.
Volume: 17
Issue: 5
Pages: 1334-44
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Publication
16837631 | J:129286
First Author: Dai C
Year: 2006
Journal: J Am Soc Nephrol
Title: Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling.
Volume: 17
Issue: 8
Pages: 2164-75
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Publication
22574216 | J:264348
First Author: Judah D
Year: 2012
Journal: PLoS One
Title: Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling.
Volume: 7
Issue: 5
Pages: e36704
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Publication
35246616 | J:323947
First Author: Campillo S
Year: 2022
Journal: Exp Mol Med
Title: Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation.
Volume: 54
Issue: 3
Pages: 226-238
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Publication
23739974 | J:198641
First Author: O'Meara RW
Year: 2013
Journal: J Neurosci
Title: Integrin-linked kinase regulates process extension in oligodendrocytes via control of actin cytoskeletal dynamics.
Volume: 33
Issue: 23
Pages: 9781-93
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Publication
26562149 | J:274833
First Author: Cano-Peñalver JL
Year: 2016
Journal: Mol Med
Title: Renal Integrin-Linked Kinase Depletion Induces Kidney cGMP-Axis Upregulation: Consequences on Basal and Acutely Damaged Renal Function.
Volume: 21
Issue: 1
Pages: 873-885
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Publication
18846549 | J:303041
First Author: Gkretsi V
Year: 2008
Journal: Hepatology
Title: Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly.
Volume: 48
Issue: 6
Pages: 1932-41
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Publication
22971619 | J:193580
First Author: Serrano I
Year: 2012
Journal: Exp Cell Res
Title: Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF).
Volume: 318
Issue: 19
Pages: 2470-81
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Publication
18234842 | J:172934
First Author: Nakrieko KA
Year: 2008
Journal: Mol Biol Cell
Title: Impaired hair follicle morphogenesis and polarized keratinocyte movement upon conditional inactivation of integrin-linked kinase in the epidermis.
Volume: 19
Issue: 4
Pages: 1462-73
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Publication
19920070 | J:156399
First Author: Donthamsetty S
Year: 2010
Journal: Toxicol Sci
Title: Liver-specific ablation of integrin-linked kinase in mice results in enhanced and prolonged cell proliferation and hepatomegaly after phenobarbital administration.
Volume: 113
Issue: 2
Pages: 358-66
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Publication
18772455 | J:142431
First Author: Tucker KL
Year: 2008
Journal: Blood
Title: A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.
Volume: 112
Issue: 12
Pages: 4523-31
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Publication
31653783 | J:292494
First Author: Huang M
Year: 2019
Journal: J Am Soc Nephrol
Title: Integrin-Linked Kinase Deficiency in Collecting Duct Principal Cell Promotes Necroptosis of Principal Cell and Contributes to Kidney Inflammation and Fibrosis.
Volume: 30
Issue: 11
Pages: 2073-2090
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Publication
27899483 | J:246637
First Author: Williams AS
Year: 2017
Journal: Diabetes
Title: Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance.
Volume: 66
Issue: 2
Pages: 325-334
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Publication
15340074 | J:92970
First Author: Friedrich EB
Year: 2004
Journal: Mol Cell Biol
Title: Integrin-linked kinase regulates endothelial cell survival and vascular development.
Volume: 24
Issue: 18
Pages: 8134-44
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Publication
27207548 | J:249466
First Author: Kang L
Year: 2016
Journal: Diabetes
Title: Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice.
Volume: 65
Issue: 6
Pages: 1590-600
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Publication
17485490 | J:134724
First Author: Lorenz K
Year: 2007
Journal: J Cell Biol
Title: Integrin-linked kinase is required for epidermal and hair follicle morphogenesis.
Volume: 177
Issue: 3
Pages: 501-13
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Publication
12547824 | J:82576
First Author: Vespa A
Year: 2003
Journal: J Biol Chem
Title: Ca2+-dependent localization of integrin-linked kinase to cell junctions in differentiating keratinocytes.
Volume: 278
Issue: 13
Pages: 11528-35
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Publication
15975904 | J:104071
First Author: Vespa A
Year: 2005
Journal: Mol Biol Cell
Title: A novel role for integrin-linked kinase in epithelial sheet morphogenesis.
Volume: 16
Issue: 9
Pages: 4084-95
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Publication
18535176 | J:137355
First Author: Ho B
Year: 2008
Journal: Am J Pathol
Title: Integrin-linked kinase in the vascular smooth muscle cell response to injury.
Volume: 173
Issue: 1
Pages: 278-88
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Publication
21351095 | J:181016
First Author: Matsui Y
Year: 2012
Journal: Int J Cancer
Title: The importance of integrin-linked kinase in the regulation of bladder cancer invasion.
Volume: 130
Issue: 3
Pages: 521-31
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Publication
12686550 | J:197597
First Author: Troussard AA
Year: 2003
Journal: J Biol Chem
Title: Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation.
Volume: 278
Issue: 25
Pages: 22374-8
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Publication
26831726 | J:315569
 
First Author: O'Meara RW
Year: 2016
Journal: BMC Neurosci
Title: A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility.
Volume: 17
Pages: 7
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Publication
24508783 | J:319053
 
First Author: Griera M
Year: 2014
Journal: Int J Biochem Cell Biol
Title: Integrin linked kinase (ILK) regulates podosome maturation and stability in dendritic cells.
Volume: 50
Pages: 47-54
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Publication
38077324 | J:343421
 
First Author: Ahmed AU
Year: 2023
Journal: Front Immunol
Title: Integrin-linked kinase expression in myeloid cells promotes colon tumorigenesis.
Volume: 14
Pages: 1270194
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Publication
23877428 | J:203703
First Author: Barakat B
Year: 2013
Journal: EMBO Rep
Title: Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.
Volume: 14
Issue: 9
Pages: 837-44
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Publication
26349061 | J:227018
 
First Author: Morgner J
Year: 2015
Journal: Nat Commun
Title: Integrin-linked kinase regulates the niche of quiescent epidermal stem cells.
Volume: 6
Pages: 8198
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Publication
31748531 | J:290609
First Author: Park H
Year: 2019
Journal: Nat Commun
Title: Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy.
Volume: 10
Issue: 1
Pages: 5243
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Publication
14581460 | J:86333
First Author: Chun SJ
Year: 2003
Journal: J Cell Biol
Title: Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelination.
Volume: 163
Issue: 2
Pages: 397-408
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Publication
30726718 | J:275551
First Author: de Frutos S
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression.
Volume: 1865
Issue: 6
Pages: 1284-1297
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Publication
16314534 | J:103752
First Author: Liu E
Year: 2005
Journal: Mol Cell Biol
Title: Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival.
Volume: 25
Issue: 24
Pages: 11145-55
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Publication
26614167 | J:229386
First Author: Michalski JP
Year: 2016
Journal: J Neurochem
Title: Integrin-linked kinase regulates oligodendrocyte cytoskeleton, growth cone, and adhesion dynamics.
Volume: 136
Issue: 3
Pages: 536-49
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Publication
10574708 | J:197523
 
First Author: Li F
Year: 1999
Journal: J Cell Sci
Title: Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats.
Volume: 112 ( Pt 24)
Pages: 4589-99
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Publication
19797768 | J:153248
First Author: Kogata N
Year: 2009
Journal: Genes Dev
Title: Integrin-linked kinase controls vascular wall formation by negatively regulating Rho/ROCK-mediated vascular smooth muscle cell contraction.
Volume: 23
Issue: 19
Pages: 2278-83
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Publication
20135642 | J:161245
First Author: Tsou HK
Year: 2010
Journal: J Cell Biochem
Title: Integrin-linked kinase is involved in TNF-alpha-induced inducible nitric-oxide synthase expression in myoblasts.
Volume: 109
Issue: 6
Pages: 1244-53
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Publication
24719101 | J:208112
First Author: Porcheri C
Year: 2014
Journal: J Neurosci
Title: Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain.
Volume: 34
Issue: 15
Pages: 5222-32
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Publication
18332223 | J:135999
First Author: Wang HV
Year: 2008
Journal: J Cell Biol
Title: Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage.
Volume: 180
Issue: 5
Pages: 1037-49
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Publication
20305688 | J:168172
First Author: Pontier SM
Year: 2010
Journal: Oncogene
Title: Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer.
Volume: 29
Issue: 23
Pages: 3374-85
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Publication
16962068 | J:113091
First Author: Friedrich EB
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Role of integrin-linked kinase in vascular smooth muscle cells: regulation by statins and angiotensin II.
Volume: 349
Issue: 3
Pages: 883-9
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Publication
31972071 | J:290457
First Author: Hatem-Vaquero M
Year: 2020
Journal: Cell Physiol Biochem
Title: Integrin Linked Kinase (ILK) Downregulation as an Early Event During the Development of Metabolic Alterations in a Short-Term High Fat Diet Mice Model.
Volume: 54
Issue: 1
Pages: 71-87
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Publication
17526737 | J:123617
First Author: Mo JS
Year: 2007
Journal: Mol Cell Biol
Title: Integrin-linked kinase controls Notch1 signaling by down-regulation of protein stability through Fbw7 ubiquitin ligase.
Volume: 27
Issue: 15
Pages: 5565-74
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Publication
19211680 | J:146635
First Author: Akhtar N
Year: 2009
Journal: Development
Title: Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation.
Volume: 136
Issue: 6
Pages: 1019-27
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Publication
21150927 | J:182088
First Author: Vi L
Year: 2011
Journal: J Invest Dermatol
Title: Integrin-linked kinase is required for TGF-β1 induction of dermal myofibroblast differentiation.
Volume: 131
Issue: 3
Pages: 586-93
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Publication
28522687 | J:291498
First Author: Raman A
Year: 2017
Journal: J Am Soc Nephrol
Title: Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease.
Volume: 28
Issue: 9
Pages: 2708-2719
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Publication
24784577 | J:217140
First Author: Cano-Peñalver JL
Year: 2014
Journal: FASEB J
Title: Integrin-linked kinase regulates tubular aquaporin-2 content and intracellular location: a link between the extracellular matrix and water reabsorption.
Volume: 28
Issue: 8
Pages: 3645-59
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Publication
29297744 | J:310435
First Author: Nüchel J
Year: 2018
Journal: Autophagy
Title: TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators.
Volume: 14
Issue: 3
Pages: 465-486
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Publication
11331308 | J:279936
First Author: Tu Y
Year: 2001
Journal: J Cell Biol
Title: A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading.
Volume: 153
Issue: 3
Pages: 585-98
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Publication
11704830 | J:72669
First Author: White DE
Year: 2001
Journal: Oncogene
Title: Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.
Volume: 20
Issue: 48
Pages: 7064-72
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Publication
18269918 | J:136781
First Author: Maier S
Year: 2008
Journal: Biochim Biophys Acta
Title: Tenascin-C induction by cyclic strain requires integrin-linked kinase.
Volume: 1783
Issue: 6
Pages: 1150-62
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Publication
24260102 | J:209685
First Author: Traister A
Year: 2013
Journal: PLoS One
Title: Mutation in integrin-linked kinase (ILK(R211A)) and heat-shock protein 70 comprise a broadly cardioprotective complex.
Volume: 8
Issue: 11
Pages: e77331
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Publication
18325335 | J:189982
First Author: Matsuda C
Year: 2008
Journal: FEBS Lett
Title: Affixin activates Rac1 via betaPIX in C2C12 myoblast.
Volume: 582
Issue: 8
Pages: 1189-96
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Publication
23263281 | J:195230
First Author: Akhtar N
Year: 2013
Journal: Nat Cell Biol
Title: An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium.
Volume: 15
Issue: 1
Pages: 17-27
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Publication
23612611 | J:198827
First Author: Radovanac K
Year: 2013
Journal: EMBO J
Title: Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response.
Volume: 32
Issue: 10
Pages: 1409-24
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Publication
16914328 | J:116532
First Author: Belvindrah R
Year: 2006
Journal: Mol Cell Neurosci
Title: Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development.
Volume: 33
Issue: 2
Pages: 109-25
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Publication
30835508 | J:275975
First Author: Trefts E
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner.
Volume: 316
Issue: 6
Pages: E1118-E1135
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Publication
28736155 | J:251244
First Author: Hatem-Vaquero M
Year: 2017
Journal: Biochim Biophys Acta
Title: Integrin linked kinase regulates the transcription of AQP2 by NFATC3.
Volume: 1860
Issue: 9
Pages: 922-935
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Publication
19439446 | J:164415
First Author: Ho E
Year: 2009
Journal: Mol Biol Cell
Title: Integrin-linked kinase interactions with ELMO2 modulate cell polarity.
Volume: 20
Issue: 13
Pages: 3033-43
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Publication
23404105 | J:194046
First Author: Malan D
Year: 2013
Journal: Development
Title: Deletion of integrin linked kinase in endothelial cells results in defective RTK signaling caused by caveolin 1 mislocalization.
Volume: 140
Issue: 5
Pages: 987-95
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Publication
16317048 | J:105248
First Author: Stanchi F
Year: 2005
Journal: J Cell Sci
Title: Consequences of loss of PINCH2 expression in mice.
Volume: 118
Issue: Pt 24
Pages: 5899-910
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Publication
25995380 | J:311754
First Author: Jackson BC
Year: 2015
Journal: Mol Biol Cell
Title: An ELMO2-RhoG-ILK network modulates microtubule dynamics.
Volume: 26
Issue: 14
Pages: 2712-25
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Publication
15565145 | J:94254
First Author: Bock-Marquette I
Year: 2004
Journal: Nature
Title: Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair.
Volume: 432
Issue: 7016
Pages: 466-72
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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