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Search results 1 to 84 out of 84 for Inca1

0.043s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: macaque, rhesus
Protein Domain
Type: Family
Description: The CDK2-associated cyclin A1 is essential for spermatogenesis, and contributes to leukemogenesis, but its detailed molecular functions are unclear. Several novel cyclin A1/CDK2 interaction partners have been identified by means of a yeast triple-hybrid approach, including INCA1, KARCA1 and PROCA1. These proteins link the cyclin A1-CDK2 complex to diverse cellular processes, such as DNA repair, signalling and splicing [].One of the new genes has been cloned and characterised, and named INCA1 (inhibitor of CDK interacting with cyclin A1). The nuclear INCA1 protein is evolutionarily conserved but shares no similarity with any known gene. This novel protein and two other interacting partners serve as substrates for the cyclin A1-CDK2 kinase complex [].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 231  
Fragment?: false
Publication
First Author: Diederichs S
Year: 2004
Journal: J Biol Chem
Title: Identification of interaction partners and substrates of the cyclin A1-CDK2 complex.
Volume: 279
Issue: 32
Pages: 33727-41
Publication
First Author: Zhang F
Year: 2011
Journal: PLoS One
Title: The inhibitor of growth protein 5 (ING5) depends on INCA1 as a co-factor for its antiproliferative effects.
Volume: 6
Issue: 7
Pages: e21505
Publication
First Author: Bäumer N
Year: 2011
Journal: J Biol Chem
Title: Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling.
Volume: 286
Issue: 32
Pages: 28210-22
Publication
First Author: Bäumer N
Year: 2014
Journal: PLoS One
Title: Maintenance of leukemia-initiating cells is regulated by the CDK inhibitor Inca1.
Volume: 9
Issue: 12
Pages: e115578
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1737921
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13140
Specimen Label: GUDMAP:13140
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796521
Pattern: Spotted
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13142
Note: graded expression
Specimen Label: GUDMAP:13142
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1737321
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13139
Specimen Label: GUDMAP:13139
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1795921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13142
Specimen Label: GUDMAP:13142
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:2888021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13142
Specimen Label: GUDMAP:13142
Specimen Num: 4
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2888821
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13142
Specimen Label: GUDMAP:13142
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795021
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13139
Specimen Label: GUDMAP:13139
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2890921
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13142
Specimen Label: GUDMAP:13142
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2913821
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13141
Specimen Label: GUDMAP:13141
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:3090121
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13140
Specimen Label: GUDMAP:13140
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2918521
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13141
Specimen Label: GUDMAP:13141
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796321
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13142
Specimen Label: GUDMAP:13142
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797221
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13141
Specimen Label: GUDMAP:13141
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2894021
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13142
Specimen Label: GUDMAP:13142
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2917321
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13141
Specimen Label: GUDMAP:13141
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:3087021
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13140
Specimen Label: GUDMAP:13140
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2894521
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13142
Specimen Label: GUDMAP:13142
Detected: false
Specimen Num: 4
GXD Expression  
Probe: MGI:5001421
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5541975
Age: embryonic day 13.5
Image: GUDMAP:13142
Specimen Label: GUDMAP:13142
Detected: true
Specimen Num: 4
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
UniProt Feature
Begin: 1
Description: Protein INCA1
Type: chain
End: 231
Protein
Organism: Mus musculus/domesticus
Length: 196  
Fragment?: false
UniProt Feature
Begin: 117
Description: Essential for interaction with INCA1
Type: site
End: 117
UniProt Feature
Begin: 119
Description: Essential for interaction with INCA1
Type: site
End: 119
HT Experiment
Series Id: GSE54418
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112