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Search results 1 to 100 out of 250 for Ing1

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0.046s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Protein Domain
Type: Family
Description: Members of the ING (inhibitor of growth protein) family of tumour suppressors regulate cell cycle progression, apoptosis, and DNA repair as important cofactors of p53. Inhibitor of growth protein 1 (ING1) is the best characterised member of this family of five genes (ING1-5) with conserved plant homeodomains (PHDs) [].ING1 interacts with proliferating cell nuclear antigen (PCNA) and PCNA-interacting protein p15 (PAF) [, ]. p53 and ING1 have been shown to functionally cooperate in the activation of apoptosis []. ING1 could also induce apoptosis by translocation from the nucleus to the mitochondria where interaction with BAX stabilises this protein, promoting its pro-apoptotic function []. ING1 functions in DNA demethylation []and has a role in the early steps of multiple DNA repair pathways [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Schäfer A
Year: 2013
Journal: Genes Dev
Title: Ing1 functions in DNA demethylation by directing Gadd45a to H3K4me3.
Volume: 27
Issue: 3
Pages: 261-73
Publication  
First Author: Bose P
Year: 2013
Journal: Cell Death Dis
Title: ING1 induces apoptosis through direct effects at the mitochondria.
Volume: 4
Pages: e788
Publication
First Author: Scott M
Year: 2001
Journal: J Cell Sci
Title: UV-induced binding of ING1 to PCNA regulates the induction of apoptosis.
Volume: 114
Issue: Pt 19
Pages: 3455-62
Publication
First Author: Ha S
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Characterization of nuclear localization signal in mouse ING1 homolog protein.
Volume: 293
Issue: 1
Pages: 163-6
Publication
First Author: Han X
Year: 2008
Journal: Nat Cell Biol
Title: Tethering by lamin A stabilizes and targets the ING1 tumour suppressor.
Volume: 10
Issue: 11
Pages: 1333-40
Publication  
First Author: Leighton LJ
Year: 2018
Journal: Neuroscience
Title: A Functional Role for the Epigenetic Regulator ING1 in Activity-induced Gene Expression in Primary Cortical Neurons.
Volume: 369
Pages: 248-260
Publication
First Author: Abad M
Year: 2007
Journal: J Biol Chem
Title: Ing1 mediates p53 accumulation and chromatin modification in response to oncogenic stress.
Volume: 282
Issue: 42
Pages: 31060-7
Publication
First Author: Ha S
Year: 2002
Journal: Cancer Res
Title: Mouse ING1 homologue, a protein interacting with A1, enhances cell death and is inhibited by A1 in mammary epithelial cells.
Volume: 62
Issue: 5
Pages: 1275-8
Publication
First Author: Kichina JV
Year: 2006
Journal: Oncogene
Title: Targeted disruption of the mouse ing1 locus results in reduced body size, hypersensitivity to radiation and elevated incidence of lymphomas.
Volume: 25
Issue: 6
Pages: 857-66
Publication
First Author: Coles AH
Year: 2007
Journal: Cancer Res
Title: Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis.
Volume: 67
Issue: 5
Pages: 2054-61
Publication
First Author: Zeremski M
Year: 1999
Journal: J Biol Chem
Title: Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function.
Volume: 274
Issue: 45
Pages: 32172-81
Publication
First Author: Simpson F
Year: 2006
Journal: Exp Cell Res
Title: The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b.
Volume: 312
Issue: 1
Pages: 73-85
Publication
First Author: Garkavtsev I
Year: 1998
Journal: Nature
Title: The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control.
Volume: 391
Issue: 6664
Pages: 295-8
Publication
First Author: Ceruti JM
Year: 2013
Journal: Mol Cell Biochem
Title: Inhibitor of growth 1 (ING1) acts at early steps of multiple DNA repair pathways.
Volume: 378
Issue: 1-2
Pages: 117-26
Publication
First Author: He GH
Year: 2005
Journal: Mol Biol Evol
Title: Phylogenetic analysis of the ING family of PHD finger proteins.
Volume: 22
Issue: 1
Pages: 104-16
Protein
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 185  
Fragment?: false
Publication
First Author: Helbing CC
Year: 1997
Journal: Cancer Res
Title: A novel candidate tumor suppressor, ING1, is involved in the regulation of apoptosis.
Volume: 57
Issue: 7
Pages: 1255-8
Publication
First Author: Schäfer A
Year: 2018
Journal: Genes Dev
Title: Impaired DNA demethylation of C/EBP sites causes premature aging.
Volume: 32
Issue: 11-12
Pages: 742-762
Publication
First Author: Cheung KJ Jr
Year: 2000
Journal: Br J Cancer
Title: Expression of the novel tumour suppressor p33(ING1)is independent of p53.
Volume: 83
Issue: 11
Pages: 1468-72
Publication
First Author: Coles AH
Year: 2008
Journal: Cancer Res
Title: p37Ing1b regulates B-cell proliferation and cooperates with p53 to suppress diffuse large B-cell lymphomagenesis.
Volume: 68
Issue: 21
Pages: 8705-14
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Campos EI
Year: 2004
Journal: Cell Mol Life Sci
Title: Biological functions of the ING family tumor suppressors.
Volume: 61
Issue: 19-20
Pages: 2597-613
Publication
First Author: Rajarajacholan UK
Year: 2013
Journal: PLoS Biol
Title: The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway.
Volume: 11
Issue: 3
Pages: e1001502
GXD Expression      
Probe: MGI:3691093
Assay Type: RT-PCR
Annotation Date: 2006-12-21
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3691583
Age: postnatal adult
Specimen Label: FGO
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3691093
Assay Type: RT-PCR
Annotation Date: 2006-12-21
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3691583
Age: postnatal adult
Specimen Label: OO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3691093
Assay Type: RT-PCR
Annotation Date: 2006-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Stage: TS01
Assay Id: MGI:3691583
Age: embryonic day 0.5
Specimen Label: Zyg
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3691093
Assay Type: RT-PCR
Annotation Date: 2006-12-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:3691583
Age: embryonic day 1.0
Specimen Label: e 2C
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3691093
Assay Type: RT-PCR
Annotation Date: 2006-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:3691583
Age: embryonic day 1.0
Specimen Label: l 2C
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3691093
Assay Type: RT-PCR
Annotation Date: 2006-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160373
Stage: TS03
Assay Id: MGI:3691583
Age: embryonic day 2.0-2.5
Specimen Label: 4-8C
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3691093
Assay Type: RT-PCR
Annotation Date: 2006-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Stage: TS03
Assay Id: MGI:3691583
Age: embryonic day 3.0
Specimen Label: Mor
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3691093
Assay Type: RT-PCR
Annotation Date: 2006-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3691583
Age: embryonic day 3.5
Specimen Label: Blast
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3815809
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816613
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3815809
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816613
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815809
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816613
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3815809
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816613
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3815809
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816613
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3815809
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816613
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3815809
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816613
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3815809
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816613
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6448146
Age: postnatal adult
Image: 1
Specimen Label: liver lane 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6448146
Age: postnatal adult
Image: 1
Specimen Label: heart lane 1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6448146
Age: postnatal adult
Image: 1
Specimen Label: testis lane 1
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6448147
Age: postnatal adult
Image: 1
Specimen Label: liver lane 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6448147
Age: postnatal adult
Image: 1
Specimen Label: heart lane 2
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6448147
Age: postnatal adult
Image: 1
Specimen Label: testis lane 2
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:6448143
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6448148
Age: postnatal adult
Image: 1
Specimen Label: liver lane 3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6448143
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6448148
Age: postnatal adult
Image: 1
Specimen Label: heart lane 3
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6448143
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6448148
Age: postnatal adult
Image: 1
Specimen Label: testis lane 3
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:6448144
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6448149
Age: postnatal adult
Image: 1
Specimen Label: liver lane 4
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6448144
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6448149
Age: postnatal adult
Image: 1
Specimen Label: heart lane 4
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6448144
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6448149
Age: postnatal adult
Image: 1
Specimen Label: testis lane 4
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6448150
Age: postnatal adult
Image: 5
Specimen Label: thymus
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6448150
Age: postnatal adult
Image: 5
Specimen Label: spleen
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6448150
Age: postnatal adult
Image: 5
Specimen Label: liver
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6448150
Age: postnatal adult
Image: 5
Specimen Label: lung
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6448150
Age: postnatal adult
Image: 5
Specimen Label: brain
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6448150
Age: postnatal adult
Image: 5
Specimen Label: heart
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6448141
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6448150
Age: postnatal adult
Image: 5
Specimen Label: testis
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6448151
Age: postnatal adult
Image: 5
Specimen Label: thymus
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6448151
Age: postnatal adult
Image: 5
Specimen Label: spleen
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6448151
Age: postnatal adult
Image: 5
Specimen Label: liver
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6448151
Age: postnatal adult
Image: 5
Specimen Label: lung
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6448151
Age: postnatal adult
Image: 5
Specimen Label: brain
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6448151
Age: postnatal adult
Image: 5
Specimen Label: heart
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:6448142
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6448151
Age: postnatal adult
Image: 5
Specimen Label: testis
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6448143
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6448152
Age: postnatal adult
Image: 5
Specimen Label: thymus
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6448143
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6448152
Age: postnatal adult
Image: 5
Specimen Label: spleen
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6448143
Assay Type: Northern blot
Annotation Date: 2020-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6448152
Age: postnatal adult
Image: 5
Specimen Label: liver
Detected: true
Specimen Num: 3