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Search results 1 to 100 out of 796 for Insr

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Type Details Score
Gene
3643 | INSR
Type: gene
Organism: human
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Gene
455649 | INSR
Type: gene
Organism: chimpanzee
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Gene
408017 | INSR
Type: gene
Organism: cattle
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Gene
420133 | INSR
Type: gene
Organism: chicken
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Gene
706009 | INSR
Type: gene
Organism: macaque, rhesus
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Gene
100492718 | insr
Type: gene
Organism: frog, western clawed
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Gene
24954 | Insr
Type: gene
Organism: rat
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Gene
484990 | INSR
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:96575 | Insr
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15864351 | J:98087
First Author: Okamoto H
Year: 2005
Journal: J Clin Invest
Title: Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action.
Volume: 115
Issue: 5
Pages: 1314-22
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Publication
17299086 | J:121915
First Author: Kim JJ
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2.
Volume: 292
Issue: 6
Pages: E1694-701
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Publication
26567220 | J:246896
First Author: Wei W
Year: 2016
Journal: J Cell Sci
Title: The NF-κB-modulated microRNAs miR-195 and miR-497 inhibit myoblast proliferation by targeting Igf1r, Insr and cyclin genes.
Volume: 129
Issue: 1
Pages: 39-50
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190617
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Insr
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190617
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Insr
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190617
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Insr
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190617
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Insr
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190617
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Insr
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190617
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Insr
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190617
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Insr
Detected: true
Specimen Num: 7
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Publication
- | J:267535
     
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Patently.
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Publication
- | J:267534
     
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for gummi_bear.
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Publication
21239487 | J:170633
First Author: Lin HV
Year: 2011
Journal: J Biol Chem
Title: Reconstitution of insulin action in muscle, white adipose tissue, and brain of insulin receptor knock-out mice fails to rescue diabetes.
Volume: 286
Issue: 11
Pages: 9797-804
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Publication
12459269 | J:80773
First Author: Baudry A
Year: 2002
Journal: Gene
Title: Partial rescue of insulin receptor-deficient mice by transgenic complementation with an activated insulin receptor in the liver.
Volume: 299
Issue: 1-2
Pages: 219-25
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Publication
19933998 | J:164160
First Author: Lin HV
Year: 2010
Journal: Diabetes
Title: Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons.
Volume: 59
Issue: 2
Pages: 337-46
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Publication
35523180 | J:326450
First Author: Chidambaram S
Year: 2022
Journal: Stem Cell Reports
Title: Subventricular zone adult mouse neural stem cells require insulin receptor for self-renewal.
Volume: 17
Issue: 6
Pages: 1411-1427
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Publication
37913774 | J:342860
First Author: Podmore L
Year: 2023
Journal: Cell Rep
Title: Insulin receptor loss impairs mammary tumorigenesis in mice.
Volume: 42
Issue: 11
Pages: 113251
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Publication
34460911 | J:327000
 
First Author: Warmke N
Year: 2021
Journal: Endocrinology
Title: Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling.
Volume: 162
Issue: 11
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Publication
32816962 | J:300711
First Author: Brierley GV
Year: 2020
Journal: Diabetes
Title: Anti-Insulin Receptor Antibodies Improve Hyperglycemia in a Mouse Model of Human Insulin Receptoropathy.
Volume: 69
Issue: 11
Pages: 2481-2489
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Publication
8612577 | J:32538
First Author: Joshi RL
Year: 1996
Journal: EMBO J
Title: Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality.
Volume: 15
Issue: 7
Pages: 1542-7
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Publication
34271222 | J:330003
 
First Author: Luo F
Year: 2021
Journal: Mol Metab
Title: Missense variant in insulin receptor (Y1355H) segregates in family with fatty liver disease.
Volume: 53
Pages: 101299
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Publication
27760050 | J:239615
First Author: Petersen MC
Year: 2016
Journal: J Clin Invest
Title: Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance.
Volume: 126
Issue: 11
Pages: 4361-4371
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Publication
37175762 | J:338280
 
First Author: Sohail S
Year: 2023
Journal: Int J Mol Sci
Title: Sex Modulates Response to Renal-Tubule-Targeted Insulin Receptor Deletion in Mice.
Volume: 24
Issue: 9
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Publication
16127460 | J:100915
First Author: Banks AS
Year: 2005
Journal: J Clin Invest
Title: Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans.
Volume: 115
Issue: 9
Pages: 2462-71
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Publication
26573296 | J:229018
First Author: Xia P
Year: 2015
Journal: J Exp Med
Title: Insulin-InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages.
Volume: 212
Issue: 13
Pages: 2305-21
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Publication
14722613 | J:87564
First Author: Kitamura T
Year: 2004
Journal: J Clin Invest
Title: Mosaic analysis of insulin receptor function.
Volume: 113
Issue: 2
Pages: 209-19
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Publication
3066742 | J:9626
First Author: Wang LM
Year: 1988
Journal: Genomics
Title: Chromosome assignment of mouse insulin, colony stimulating factor 1, and low-density lipoprotein receptors.
Volume: 3
Issue: 2
Pages: 172-6
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Publication
23671263 | J:200951
First Author: Gahete MD
Year: 2013
Journal: Endocrinology
Title: Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.
Volume: 154
Issue: 7
Pages: 2410-20
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Publication
32478834 | J:294936
 
First Author: Wu D
Year: 2020
Journal: J Exp Med
Title: T reg-specific insulin receptor deletion prevents diet-induced and age-associated metabolic syndrome.
Volume: 217
Issue: 8
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Publication
31713233 | J:285779
First Author: Wu D
Year: 2020
Journal: Immunology
Title: Ectopic germline recombination activity of the widely used Foxp3-YFP-Cre mouse: a case report.
Volume: 159
Issue: 2
Pages: 231-241
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Publication
35328354 | J:322862
 
First Author: Milanova IV
Year: 2022
Journal: Int J Mol Sci
Title: Loss of Microglial Insulin Receptor Leads to Sex-Dependent Metabolic Disorders in Obese Mice.
Volume: 23
Issue: 6
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Publication
34037749 | J:343883
 
First Author: Walker AMN
Year: 2021
Journal: Endocrinology
Title: Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis.
Volume: 162
Issue: 8
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Publication
29401624 | J:273822
First Author: Neirijnck Y
Year: 2018
Journal: FASEB J
Title: Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells.
Volume: 32
Issue: 6
Pages: 3321-3335
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Publication
22319636 | J:185235
First Author: Plum L
Year: 2012
Journal: PLoS One
Title: InsR/FoxO1 signaling curtails hypothalamic POMC neuron number.
Volume: 7
Issue: 2
Pages: e31487
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Publication
27150392 | J:246852
First Author: Liu J
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Type 1 Deiodinase Regulates ApoA-I Gene Expression and ApoA-I Synthesis Independent of Thyroid Hormone Signaling.
Volume: 36
Issue: 7
Pages: 1356-66
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Publication
25685696 | J:223522
First Author: Chong AC
Year: 2015
Journal: Mol Metab
Title: Central insulin signaling modulates hypothalamus-pituitary-adrenal axis responsiveness.
Volume: 4
Issue: 2
Pages: 83-92
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Publication
23518924 | J:283285
First Author: Pitetti JL
Year: 2013
Journal: Mol Endocrinol
Title: An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice.
Volume: 27
Issue: 5
Pages: 814-27
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Publication
20032056 | J:158405
First Author: Liang L
Year: 2010
Journal: Endocrinology
Title: Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis.
Volume: 151
Issue: 2
Pages: 741-7
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Publication
30292429 | J:272636
 
First Author: Evans MC
Year: 2018
Journal: Horm Behav
Title: Leptin and insulin do not exert redundant control of metabolic or emotive function via dopamine neurons.
Volume: 106
Pages: 93-104
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Publication
25116708 | J:218718
First Author: Evans MC
Year: 2014
Journal: Endocrinology
Title: Insulin action on GABA neurons is a critical regulator of energy balance but not fertility in mice.
Volume: 155
Issue: 11
Pages: 4368-79
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Publication
32173454 | J:314325
 
First Author: Glendining KA
Year: 2020
Journal: Brain Behav Immun
Title: Maternal obesity modulates sexually dimorphic epigenetic regulation and expression of leptin receptor in offspring hippocampus.
Volume: 88
Pages: 151-160
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Publication
30576429 | J:273133
First Author: Neirijnck Y
Year: 2019
Journal: Endocrinology
Title: Tumor Suppressor PTEN Regulates Negatively Sertoli Cell Proliferation, Testis Size, and Sperm Production In Vivo.
Volume: 160
Issue: 2
Pages: 387-398
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Publication
20947509 | J:167586
First Author: Xuan S
Year: 2010
Journal: J Biol Chem
Title: Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.
Volume: 285
Issue: 52
Pages: 41044-50
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Publication
28687614 | J:246859
First Author: Madhusudhan T
Year: 2017
Journal: Blood
Title: Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function.
Volume: 130
Issue: 12
Pages: 1445-1455
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Publication
33077977 | J:305004
First Author: Zhou B
Year: 2020
Journal: Nat Microbiol
Title: Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling.
Volume: 5
Issue: 12
Pages: 1576-1587
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Publication
30909860 | J:273626
First Author: Wang K
Year: 2019
Journal: BMC Dev Biol
Title: Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development.
Volume: 19
Issue: 1
Pages: 5
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Publication
26888756 | J:250858
 
First Author: Groeneveld MP
Year: 2016
Journal: Sci Rep
Title: Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production.
Volume: 6
Pages: 21105
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Publication
30376348 | J:273890
First Author: Borges BC
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Insulin signaling in LepR cells modulates fat and glucose homeostasis independent of leptin.
Volume: 316
Issue: 1
Pages: E121-E134
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Publication
12101187 | J:79280
First Author: Kido Y
Year: 2002
Journal: J Biol Chem
Title: Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance.
Volume: 277
Issue: 39
Pages: 36740-7
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Publication
15254588 | J:91350
First Author: Okamoto H
Year: 2004
Journal: J Clin Invest
Title: Transgenic rescue of insulin receptor-deficient mice.
Volume: 114
Issue: 2
Pages: 214-23
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Publication
31318893 | J:277295
First Author: Jin J
Year: 2019
Journal: PLoS One
Title: Igf1R/InsR function is required for axon extension and corpus callosum formation.
Volume: 14
Issue: 7
Pages: e0219362
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Publication
21429986 | J:171220
First Author: Li P
Year: 2011
Journal: Development
Title: IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.
Volume: 138
Issue: 9
Pages: 1795-805
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Publication
33505018 | J:305792
First Author: Ansarullah
Year: 2021
Journal: Nature
Title: Inceptor counteracts insulin signalling in β-cells to control glycaemia.
Volume: 590
Issue: 7845
Pages: 326-331
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Publication
11463843 | J:70602
First Author: Kitamura T
Year: 2001
Journal: Mol Cell Biol
Title: Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor.
Volume: 21
Issue: 16
Pages: 5624-30
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Publication
21641549 | J:176088
First Author: Deyev IE
Year: 2011
Journal: Cell Metab
Title: Insulin receptor-related receptor as an extracellular alkali sensor.
Volume: 13
Issue: 6
Pages: 679-89
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Publication
21681845 | J:175639
First Author: Erickson RP
Year: 2011
Journal: Mol Reprod Dev
Title: Insulin receptor-related (Irr) is expressed in pre-implantation embryos: a possible relationship to "growth factor Y" and sex determination.
Volume: 78
Issue: 8
Pages: 552
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Protein Coding Gene
MGP_CAROLIEiJ_G0030765 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033299 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033213 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032996 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033792 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032969 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033123 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032432 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021238 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031873 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2557333 | J:32474
First Author: Flores-Riveros JR
Year: 1989
Journal: J Biol Chem
Title: Substrate phosphorylation catalyzed by the insulin receptor tyrosine kinase. Kinetic correlation to autophosphorylation of specific sites in the beta subunit.
Volume: 264
Issue: 36
Pages: 21557-72
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Publication
2602374 | J:10185
First Author: Sibley E
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Characterization of the mouse insulin receptor gene promoter.
Volume: 86
Issue: 24
Pages: 9732-6
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Publication
9398630 | J:44320
First Author: McKeon C
Year: 1997
Journal: Biochem Biophys Res Commun
Title: A conserved region in the first intron of the insulin receptor gene binds nuclear proteins during adipocyte differentiation.
Volume: 240
Issue: 3
Pages: 701-6
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Publication
8083370 | J:20454
First Author: Huang Z
Year: 1994
Journal: J Clin Invest
Title: Hyperinsulinemia is associated with altered insulin receptor mRNA splicing in muscle of the spontaneously obese diabetic rhesus monkey.
Volume: 94
Issue: 3
Pages: 1289-96
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Publication
35044446 | J:324762
First Author: Kavazović I
Year: 2022
Journal: Diabetes
Title: Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory CD8 T-Cell Dysfunction.
Volume: 71
Issue: 4
Pages: 706-721
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Publication
31199472 | J:279774
First Author: Ren H
Year: 2019
Journal: Endocrinology
Title: Altered Central Nutrient Sensing in Male Mice Lacking Insulin Receptors in Glut4-Expressing Neurons.
Volume: 160
Issue: 9
Pages: 2038-2048
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Publication
16485043 | J:106481
First Author: Okamoto H
Year: 2006
Journal: J Clin Invest
Title: Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance.
Volume: 116
Issue: 3
Pages: 775-82
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Publication
11602628 | J:72231
First Author: Guerra C
Year: 2001
Journal: J Clin Invest
Title: Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance.
Volume: 108
Issue: 8
Pages: 1205-13
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Publication
14981233 | J:88646
First Author: Schubert M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Role for neuronal insulin resistance in neurodegenerative diseases.
Volume: 101
Issue: 9
Pages: 3100-5
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Publication
21284985 | J:169563
First Author: Scherer T
Year: 2011
Journal: Cell Metab
Title: Brain insulin controls adipose tissue lipolysis and lipogenesis.
Volume: 13
Issue: 2
Pages: 183-94
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Publication
20547974 | J:169634
First Author: Diggs-Andrews KA
Year: 2010
Journal: Diabetes
Title: Brain insulin action regulates hypothalamic glucose sensing and the counterregulatory response to hypoglycemia.
Volume: 59
Issue: 9
Pages: 2271-80
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Publication
25733901 | J:220708
First Author: Kleinridders A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Insulin resistance in brain alters dopamine turnover and causes behavioral disorders.
Volume: 112
Issue: 11
Pages: 3463-8
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Publication
11000114 | J:64790
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First Author: Scherer T
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Journal: Diabetes
Title: Insulin Regulates Hepatic Triglyceride Secretion and Lipid Content via Signaling in the Brain.
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Journal: Diabetes
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Year: 2020
Journal: Sci Rep
Title: Postnatal loss of the insulin receptor in osteoprogenitor cells does not impart a metabolic phenotype.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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