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Search results 1 to 78 out of 78 for Irf2bp2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chen HH
Year: 2015
Journal: Circ Res
Title: IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis.
Volume: 117
Issue: 8
Pages: 671-83
Publication
First Author: Teng AC
Year: 2010
Journal: FASEB J
Title: IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator of VEGFA expression.
Volume: 24
Issue: 12
Pages: 4825-34
Publication
First Author: Fang J
Year: 2017
Journal: Hypertension
Title: Control of Pathological Cardiac Hypertrophy by Transcriptional Corepressor IRF2BP2 (Interferon Regulatory Factor-2 Binding Protein 2).
Volume: 70
Issue: 3
Pages: 515-523
Publication  
First Author: Cruz SA
Year: 2017
Journal: Front Cell Neurosci
Title: Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.
Volume: 11
Pages: 201
Publication  
First Author: Stadhouders R
Year: 2015
Journal: Nat Commun
Title: Control of developmentally primed erythroid genes by combinatorial co-repressor actions.
Volume: 6
Pages: 8893
Publication  
First Author: Vilmundarson RO
Year: 2022
Journal: Front Immunol
Title: Savior Siblings Might Rescue Fetal Lethality But Not Adult Lymphoma in Irf2bp2-Null Mice.
Volume: 13
Pages: 868053
Publication
First Author: Hari A
Year: 2017
Journal: Sci Rep
Title: IRF2BP2-deficient microglia block the anxiolytic effect of enhanced postnatal care.
Volume: 7
Issue: 1
Pages: 9836
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1770125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3274825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Ubiquitous
Stage: TS17
Assay Id: MGI:4881757
Age: embryonic day 10.5
Specimen Label: 6B
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:4881757
Age: embryonic day 15.5
Specimen Label: 6D
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3598825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1684625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Ma YL
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Suppressing Irf2bp2 expressions accelerates metabolic syndrome-associated brain injury and hepatic dyslipidemia.
Volume: 503
Issue: 3
Pages: 1651-1658
Allele
Name: interferon regulatory factor 2 binding protein 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Keller MD
Year: 2016
Journal: J Allergy Clin Immunol
Title: Mutation in IRF2BP2 is responsible for a familial form of common variable immunodeficiency disorder.
Volume: 138
Issue: 2
Pages: 544-550.e4
DO Term
Allele
Name: interferon regulatory factor 2 binding protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Protein
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
Publication
First Author: Childs KS
Year: 2003
Journal: Nucleic Acids Res
Title: Identification of novel co-repressor molecules for Interferon Regulatory Factor-2.
Volume: 31
Issue: 12
Pages: 3016-26
Publication
First Author: Marcogliese PC
Year: 2018
Journal: Am J Hum Genet
Title: IRF2BPL Is Associated with Neurological Phenotypes.
Volume: 103
Issue: 2
Pages: 245-260
Protein Domain
Type: Domain
Description: Interferon regulatory factor 2-binding protein 1 and 2 (IRF-2BP1/2) and their homologue IRF-2BP-like (also known as IRF-2BPL or C14orf4) () are nuclear transcriptional repressor proteins that bind to the C-terminal repression domain of IRF-2 and can inhibit both enhancer-activated and basal transcription. They contain N-terminal zinc finger and C-terminal RING finger domains [, , ]. Mutations in IRF2BP2 are responsible for a Familial Form of Common Variable Immunodeficiency Disorder (CVID), one of the most frequently diagnosed forms of primary immunodeficiency characterised by low quantity of IgG and IgA and poor specific antibody production []. IRF2BPL may play a role in the development of the central nervous system and in neuronal maintenance [].This entry represents the N-terminal zinc finger domain of IRF-2BP1 and IRF-2BP2.
Protein Domain
Type: Homologous_superfamily
Description: Interferon regulatory factor 2-binding protein 1 and 2 (IRF-2BP1/2) and their homologue IRF-2BP-like (also known as IRF-2BPL or C14orf4) () are nuclear transcriptional repressor proteins that bind to the C-terminal repression domain of IRF-2 and can inhibit both enhancer-activated and basal transcription. They contain N-terminal zinc finger and C-terminal RING finger domains [, , ]. Mutations in IRF2BP2 are responsible for a Familial Form of Common Variable Immunodeficiency Disorder (CVID), one of the most frequently diagnosed forms of primary immunodeficiency characterised by low quantity of IgG and IgA and poor specific antibody production []. IRF2BPL may play a role inthe development of the central nervous system and in neuronal maintenance [].This superfamily represents the C-terminal C3HC4-type RING finger of IRF2BP1/2 and IRF2BPL [].
Protein
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: false