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Search results 1 to 84 out of 84 for Irf2bp2

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Hits by Strain

Type Details Score
Gene
359948 | IRF2BP2
Type: gene
Organism: human
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Gene
394851 | irf2bp2
Type: gene
Organism: frog, western clawed
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Gene
488961 | IRF2BP2
Type: gene
Organism: dog, domestic
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Gene
469713 | IRF2BP2
Type: gene
Organism: chimpanzee
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Gene
679357 | Irf2bp2
Type: gene
Organism: rat
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Gene
781665 | IRF2BP2
Type: gene
Organism: cattle
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Gene
428585 | IRF2BP2
Type: gene
Organism: chicken
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Gene
718705 | IRF2BP2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2443921 | Irf2bp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26195219 | J:249107
First Author: Chen HH
Year: 2015
Journal: Circ Res
Title: IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis.
Volume: 117
Issue: 8
Pages: 671-83
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Publication
20702774 | J:166377
First Author: Teng AC
Year: 2010
Journal: FASEB J
Title: IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator of VEGFA expression.
Volume: 24
Issue: 12
Pages: 4825-34
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Publication
28716987 | J:302083
First Author: Fang J
Year: 2017
Journal: Hypertension
Title: Control of Pathological Cardiac Hypertrophy by Transcriptional Corepressor IRF2BP2 (Interferon Regulatory Factor-2 Binding Protein 2).
Volume: 70
Issue: 3
Pages: 515-523
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Publication
28769762 | J:276818
 
First Author: Cruz SA
Year: 2017
Journal: Front Cell Neurosci
Title: Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.
Volume: 11
Pages: 201
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Publication
26593974 | J:228010
 
First Author: Stadhouders R
Year: 2015
Journal: Nat Commun
Title: Control of developmentally primed erythroid genes by combinatorial co-repressor actions.
Volume: 6
Pages: 8893
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Publication
35865523 | J:326618
 
First Author: Vilmundarson RO
Year: 2022
Journal: Front Immunol
Title: Savior Siblings Might Rescue Fetal Lethality But Not Adult Lymphoma in Irf2bp2-Null Mice.
Volume: 13
Pages: 868053
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Publication
28852125 | J:256245
First Author: Hari A
Year: 2017
Journal: Sci Rep
Title: IRF2BP2-deficient microglia block the anxiolytic effect of enhanced postnatal care.
Volume: 7
Issue: 1
Pages: 9836
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Protein Coding Gene
MGP_CAROLIEiJ_G0031730 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034202 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034268 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033979 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443921 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034108 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034053 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034197 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034099 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034807 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033009 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033424 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023327 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032847 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1770125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3598825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Ubiquitous
Stage: TS17
Assay Id: MGI:4881757
Age: embryonic day 10.5
Specimen Label: 6B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:4881757
Age: embryonic day 15.5
Specimen Label: 6D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1684625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4881754
Assay Type: Immunohistochemistry
Annotation Date: 2011-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3274825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:4881757
Age: embryonic day 17.5
Specimen Label: 6F, G
Detected: true
Specimen Num: 3
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30131248 | J:271987
First Author: Ma YL
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Suppressing Irf2bp2 expressions accelerates metabolic syndrome-associated brain injury and hepatic dyslipidemia.
Volume: 503
Issue: 3
Pages: 1651-1658
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Publication
27016798 | -
First Author: Keller MD
Year: 2016
Journal: J Allergy Clin Immunol
Title: Mutation in IRF2BP2 is responsible for a familial form of common variable immunodeficiency disorder.
Volume: 138
Issue: 2
Pages: 544-550.e4
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Allele
Irf2bp2<em2Smoc> | MGI:7290574
Name: interferon regulatory factor 2 binding protein 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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DO Term
DOID:0081156 | common variable immunodeficiency 14
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Strain
MGI:6770864 | C57BL/6JSmoc-Irf2Bp2<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Irf2bp2<em1Smoc> | MGI:7290573
Name: interferon regulatory factor 2 binding protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6770863 | C57BL/6JSmoc-Irf2bp2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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HT Experiment
E-MTAB-11558 | cDNA microarray expression data of heart, skeletal muscle and liver comparing Irf2bp2-null mice to wild type controls
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein
Q8K3X4
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: false
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Protein
E9Q1P8
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
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Publication
12799427 | J:83986
First Author: Childs KS
Year: 2003
Journal: Nucleic Acids Res
Title: Identification of novel co-repressor molecules for Interferon Regulatory Factor-2.
Volume: 31
Issue: 12
Pages: 3016-26
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Publication
30057031 | -
First Author: Marcogliese PC
Year: 2018
Journal: Am J Hum Genet
Title: IRF2BPL Is Associated with Neurological Phenotypes.
Volume: 103
Issue: 2
Pages: 245-260
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Protein Domain
IPR022750 | Interferon_reg_fac2-bd1_2_Znf
Type: Domain
Description: Interferon regulatory factor 2-binding protein 1 and 2 (IRF-2BP1/2) and their homologue IRF-2BP-like (also known as IRF-2BPL or C14orf4) () are nuclear transcriptional repressor proteins that bind to the C-terminal repression domain of IRF-2 and can inhibit both enhancer-activated and basal transcription. They contain N-terminal zinc finger and C-terminal RING finger domains [, , ]. Mutations in IRF2BP2 are responsible for a Familial Form of Common Variable Immunodeficiency Disorder (CVID), one of the most frequently diagnosed forms of primary immunodeficiency characterised by low quantity of IgG and IgA and poor specific antibody production []. IRF2BPL may play a role in the development of the central nervous system and in neuronal maintenance [].This entry represents the N-terminal zinc finger domain of IRF-2BP1 and IRF-2BP2.
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Protein Domain
IPR044882 | I2BP1/2_C3HC4-RING_sf
Type: Homologous_superfamily
Description: Interferon regulatory factor 2-binding protein 1 and 2 (IRF-2BP1/2) and their homologue IRF-2BP-like (also known as IRF-2BPL or C14orf4) () are nuclear transcriptional repressor proteins that bind to the C-terminal repression domain of IRF-2 and can inhibit both enhancer-activated and basal transcription. They contain N-terminal zinc finger and C-terminal RING finger domains [, , ]. Mutations in IRF2BP2 are responsible for a Familial Form of Common Variable Immunodeficiency Disorder (CVID), one of the most frequently diagnosed forms of primary immunodeficiency characterised by low quantity of IgG and IgA and poor specific antibody production []. IRF2BPL may play a role inthe development of the central nervous system and in neuronal maintenance [].This superfamily represents the C-terminal C3HC4-type RING finger of IRF2BP1/2 and IRF2BPL [].
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Protein
Q8R3Y8
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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