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Search results 1 to 100 out of 542 for Irf7

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
3665 | IRF7
Type: gene
Organism: human
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Gene
450927 | IRF7
Type: gene
Organism: chimpanzee
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Gene
100125591 | IRF7
Type: gene
Organism: cattle
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Gene
396330 | IRF7
Type: gene
Organism: chicken
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Gene
393650 | irf7
Type: gene
Organism: zebrafish
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Gene
699578 | IRF7
Type: gene
Organism: macaque, rhesus
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Gene
100496395 | irf7
Type: gene
Organism: frog, western clawed
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Gene
119864198 | IRF7
Type: gene
Organism: dog, domestic
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Gene
293624 | Irf7
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1859212 | Irf7
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32169844 | J:288488
First Author: Lee KJ
Year: 2020
Journal: J Immunol
Title: Negative Regulation of IKKε-Mediated IRF7 Phosphorylation by HSP70.
Volume: 204
Issue: 9
Pages: 2562-2574
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Publication
27697837 | J:237414
First Author: Bao M
Year: 2016
Journal: J Exp Med
Title: NFATC3 promotes IRF7 transcriptional activity in plasmacy--toid dendritic cells.
Volume: 213
Issue: 11
Pages: 2383-2398
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Publication
30932349 | J:294253
First Author: Simons KH
Year: 2019
Journal: J Cell Mol Med
Title: IRF3 and IRF7 mediate neovascularization via inflammatory cytokines.
Volume: 23
Issue: 6
Pages: 3888-3896
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Publication
16472772 | J:105893
First Author: Prakash A
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Regulation of IRF7 through cell type-specific protein stability.
Volume: 342
Issue: 1
Pages: 50-6
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Publication
22815909 | J:189607
First Author: Owens BM
Year: 2012
Journal: PLoS One
Title: IRF7 regulates TLR2-mediated activation of splenic CD11c(hi) dendritic cells.
Volume: 7
Issue: 7
Pages: e41050
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Publication
28092673 | J:271955
First Author: Yang Q
Year: 2017
Journal: Oncogene
Title: IRF7 regulates the development of granulocytic myeloid-derived suppressor cells through S100A9 transrepression in cancer.
Volume: 36
Issue: 21
Pages: 2969-2980
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Publication
25319247 | J:222321
First Author: Edwards CL
Year: 2015
Journal: Eur J Immunol
Title: Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection.
Volume: 45
Issue: 1
Pages: 130-41
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Publication
27122612 | J:249562
First Author: Puthia M
Year: 2016
Journal: Sci Transl Med
Title: IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections.
Volume: 8
Issue: 336
Pages: 336ra59
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Publication
15361868 | J:336429
First Author: Kawai T
Year: 2004
Journal: Nat Immunol
Title: Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6.
Volume: 5
Issue: 10
Pages: 1061-8
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Publication
32641587 | J:301768
 
First Author: Senatus L
Year: 2020
Journal: JCI Insight
Title: RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism.
Volume: 5
Issue: 13
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Publication
23042151 | J:188556
First Author: Siednienko J
Year: 2012
Journal: Nat Immunol
Title: Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons.
Volume: 13
Issue: 11
Pages: 1055-62
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Publication
- | J:159358
     
First Author: Blasius A
Year: 2010
Journal: MGI Direct Data Submission
Title: Inept is an allele of Irf7
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Publication
18710948 | J:140962
First Author: Ning S
Year: 2008
Journal: Mol Cell Biol
Title: TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1.
Volume: 28
Issue: 20
Pages: 6536-46
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Publication
17513736 | J:147844
First Author: Yasuda K
Year: 2007
Journal: J Immunol
Title: Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF)5 and IRF7 dependent and is required for IL-6 production.
Volume: 178
Issue: 11
Pages: 6876-85
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Publication
23956435 | J:205872
First Author: Wang J
Year: 2013
Journal: J Immunol
Title: Negative regulation of Nmi on virus-triggered type I IFN production by targeting IRF7.
Volume: 191
Issue: 6
Pages: 3393-9
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GO Term
GO:0039557 | symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity
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Ontology Term
- | Inhibition of host IRF7 by virus
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Publication
23490048 | J:259644
First Author: Li W
Year: 2013
Journal: Virology
Title: Interferon regulatory factor 7 (IRF7) is required for the optimal initial control but not subsequent clearance of lymphocytic choriomeningitis virus infection in mice.
Volume: 439
Issue: 2
Pages: 152-62
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Publication
23416614 | J:194467
First Author: Lee MS
Year: 2013
Journal: Nat Immunol
Title: OASL1 inhibits translation of the type I interferon-regulating transcription factor IRF7.
Volume: 14
Issue: 4
Pages: 346-55
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Publication
30639243 | J:271917
First Author: Frankiw L
Year: 2019
Journal: Mol Cell
Title: BUD13 Promotes a Type I Interferon Response by Countering Intron Retention in Irf7.
Volume: 73
Issue: 4
Pages: 803-814.e6
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Publication
25907537 | J:221417
First Author: Wang Y
Year: 2015
Journal: FEBS Lett
Title: TRIM35 negatively regulates TLR7- and TLR9-mediated type I interferon production by targeting IRF7.
Volume: 589
Issue: 12
Pages: 1322-30
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Publication
32437400 | J:289554
First Author: Kuroda M
Year: 2020
Journal: PLoS One
Title: Interferon regulatory factor 7 mediates obesity-associated MCP-1 transcription.
Volume: 15
Issue: 5
Pages: e0233390
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Publication
23695216 | J:203226
First Author: Wang XA
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistance.
Volume: 305
Issue: 4
Pages: E485-95
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Publication
36274382 | J:334693
First Author: Zhang Z
Year: 2022
Journal: Int J Med Microbiol
Title: MicroRNA-31 mediated by interferon regulatory factor 7 signaling facilitates control of Mycobacterium tuberculosis infection.
Volume: 312
Issue: 7
Pages: 151569
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Publication
22986168 | J:192474
 
First Author: Pappas DJ
Year: 2012
Journal: Neuroscience
Title: Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules.
Volume: 226
Pages: 10-20
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Publication
27527596 | J:331003
First Author: Miyagawa F
Year: 2016
Journal: J Immunol
Title: Essential Requirement for IFN Regulatory Factor 7 in Autoantibody Production but Not Development of Nephritis in Murine Lupus.
Volume: 197
Issue: 6
Pages: 2167-76
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Publication
21743479 | J:174420
First Author: Tun-Kyi A
Year: 2011
Journal: Nat Immunol
Title: Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity.
Volume: 12
Issue: 8
Pages: 733-41
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Publication
22196084 | J:303160
 
First Author: Salem M
Year: 2011
Journal: J Neuroinflammation
Title: Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice.
Volume: 8
Pages: 181
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Publication
18272964 | J:134222
First Author: Colina R
Year: 2008
Journal: Nature
Title: Translational control of the innate immune response through IRF-7.
Volume: 452
Issue: 7185
Pages: 323-8
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Publication
31775040 | J:300255
First Author: He J
Year: 2019
Journal: Cell Rep
Title: IRF-7 Is a Critical Regulator of Type 2 Innate Lymphoid Cells in Allergic Airway Inflammation.
Volume: 29
Issue: 9
Pages: 2718-2730.e6
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Publication
22095711 | J:180378
First Author: Hu Y
Year: 2011
Journal: J Immunol
Title: Guanylate binding protein 4 negatively regulates virus-induced type I IFN and antiviral response by targeting IFN regulatory factor 7.
Volume: 187
Issue: 12
Pages: 6456-62
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Publication
26329040 | J:233979
 
First Author: Wilk E
Year: 2015
Journal: BMC Genomics
Title: RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection.
Volume: 16
Pages: 655
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Publication
36394357 | J:345014
First Author: Liu BQ
Year: 2023
Journal: EMBO Rep
Title: XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7.
Volume: 24
Issue: 1
Pages: e55387
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Publication
29914621 | J:264199
   
First Author: Webster B
Year: 2018
Journal: Elife
Title: Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses.
Volume: 7
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Publication
23440417 | J:194737
First Author: Otero DC
Year: 2013
Journal: J Immunol
Title: IRF7-dependent IFN-β production in response to RANKL promotes medullary thymic epithelial cell development.
Volume: 190
Issue: 7
Pages: 3289-98
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Publication
35098923 | J:343961
   
First Author: Wang A
Year: 2022
Journal: Elife
Title: m6A modifications regulate intestinal immunity and rotavirus infection.
Volume: 11
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Publication
25304854 | J:278131
First Author: Huang L
Year: 2014
Journal: J Am Heart Assoc
Title: Interferon regulatory factor 7 protects against vascular smooth muscle cell proliferation and neointima formation.
Volume: 3
Issue: 5
Pages: e001309
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Publication
22875973 | J:305127
First Author: Zhou S
Year: 2012
Journal: J Virol
Title: Role of interferon regulatory factor 7 in T cell responses during acute lymphocytic choriomeningitis virus infection.
Volume: 86
Issue: 20
Pages: 11254-65
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Publication
27565347 | J:234468
First Author: Yockey LJ
Year: 2016
Journal: Cell
Title: Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection.
Volume: 166
Issue: 5
Pages: 1247-1256.e4
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Publication
31877196 | J:287071
First Author: Wong EB
Year: 2019
Journal: PLoS Pathog
Title: Resistance to ectromelia virus infection requires cGAS in bone marrow-derived cells which can be bypassed with cGAMP therapy.
Volume: 15
Issue: 12
Pages: e1008239
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Publication
22252317 | J:183707
First Author: Farlik M
Year: 2012
Journal: Mol Cell Biol
Title: Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression.
Volume: 32
Issue: 6
Pages: 1032-43
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Publication
22514347 | J:303149
First Author: Christensen JE
Year: 2012
Journal: J Virol
Title: Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery.
Volume: 86
Issue: 13
Pages: 7384-92
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Publication
20562259 | J:161928
First Author: Khorooshi R
Year: 2010
Journal: J Immunol
Title: Injury-induced type I IFN signaling regulates inflammatory responses in the central nervous system.
Volume: 185
Issue: 2
Pages: 1258-64
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Publication
22982991 | J:189233
First Author: Litvak V
Year: 2012
Journal: Nature
Title: A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses.
Volume: 490
Issue: 7420
Pages: 421-5
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Publication
37737190 | J:340751
First Author: Weichert L
Year: 2023
Journal: J Neuroinflammation
Title: Astrocytes evoke a robust IRF7-independent type I interferon response upon neurotropic viral infection.
Volume: 20
Issue: 1
Pages: 213
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Publication
25385836 | J:216281
First Author: Cohen M
Year: 2014
Journal: EMBO J
Title: Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7-dependent manner.
Volume: 33
Issue: 24
Pages: 2906-21
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Publication
26682986 | J:257995
First Author: Xu RH
Year: 2015
Journal: Immunity
Title: Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection.
Volume: 43
Issue: 6
Pages: 1148-59
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Publication
27793594 | J:258326
First Author: Yu X
Year: 2016
Journal: Immunity
Title: Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality.
Volume: 45
Issue: 5
Pages: 1093-1107
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Publication
20592086 | J:307848
First Author: Zhou S
Year: 2010
Journal: J Virol
Title: Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus.
Volume: 84
Issue: 18
Pages: 9452-62
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Publication
34168080 | J:307209
 
First Author: Chen Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.
Volume: 118
Issue: 26
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Publication
27129230 | J:235021
First Author: Ren Y
Year: 2016
Journal: J Biol Chem
Title: The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene.
Volume: 291
Issue: 25
Pages: 13206-15
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Publication
22761364 | J:187927
First Author: Rudd PA
Year: 2012
Journal: J Virol
Title: Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock.
Volume: 86
Issue: 18
Pages: 9888-98
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Publication
32373120 | J:303146
 
First Author: Sin WX
Year: 2020
Journal: Front Immunol
Title: IRF-7 Mediates Type I IFN Responses in Endotoxin-Challenged Mice.
Volume: 11
Pages: 640
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Publication
15800576 | J:97662
First Author: Honda K
Year: 2005
Journal: Nature
Title: IRF-7 is the master regulator of type-I interferon-dependent immune responses.
Volume: 434
Issue: 7034
Pages: 772-7
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Publication
22896628 | J:189947
First Author: Weiss G
Year: 2012
Journal: J Immunol
Title: MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7.
Volume: 189
Issue: 6
Pages: 2860-8
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Publication
30131424 | J:267220
 
First Author: Tomasello E
Year: 2018
Journal: EMBO J
Title: Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection.
Volume: 37
Issue: 19
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Publication
28342759 | J:331622
First Author: Chiriac MT
Year: 2017
Journal: Gastroenterology
Title: Activation of Epithelial Signal Transducer and Activator of Transcription 1 by Interleukin 28 Controls Mucosal Healing in Mice With Colitis and Is Increased in Mucosa of Patients With Inflammatory Bowel Disease.
Volume: 153
Issue: 1
Pages: 123-138.e8
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Publication
24278020 | J:248570
First Author: Crotta S
Year: 2013
Journal: PLoS Pathog
Title: Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia.
Volume: 9
Issue: 11
Pages: e1003773
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Publication
26468541 | J:227923
First Author: Proenca-Modena JL
Year: 2015
Journal: J Virol
Title: Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System.
Volume: 90
Issue: 1
Pages: 189-205
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Protein Coding Gene
MGP_CAROLIEiJ_G0030686 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033219 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033133 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033202 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1859212 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032246 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032888 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032993 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033135 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033026 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031950 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013885 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031797 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
18971424 | J:145035
First Author: Lang PA
Year: 2009
Journal: Blood
Title: Hematopoietic cell-derived interferon controls viral replication and virus-induced disease.
Volume: 113
Issue: 5
Pages: 1045-52
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Publication
- | J:217798
     
First Author: Dao D
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Houstonian
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Publication
19264779 | J:310800
First Author: Kinpara S
Year: 2009
Journal: J Virol
Title: Stromal cell-mediated suppression of human T-cell leukemia virus type 1 expression in vitro and in vivo by type I interferon.
Volume: 83
Issue: 10
Pages: 5101-8
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Publication
21149596 | J:169253
First Author: Beattie L
Year: 2011
Journal: Infect Immun
Title: Interferon regulatory factor 7 contributes to the control of Leishmania donovani in the mouse liver.
Volume: 79
Issue: 3
Pages: 1057-66
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Publication
20300600 | J:162877
First Author: Phillips R
Year: 2010
Journal: PLoS Pathog
Title: Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7.
Volume: 6
Issue: 3
Pages: e1000813
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Publication
21596780 | J:183066
First Author: De Ioannes P
Year: 2011
Journal: Nucleic Acids Res
Title: Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding.
Volume: 39
Issue: 16
Pages: 7300-7
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GXD Expression
GXD Expression
   
Probe: MGI:3526540
Assay Type: Northern blot
Annotation Date: 2005-02-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:3526804
Age: embryonic day 14.5
Image: 2
Specimen Label: WT
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3526540
Assay Type: Northern blot
Annotation Date: 2005-02-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:3526804
Age: embryonic day 14.5
Image: 2
Specimen Label: HET
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3526540
Assay Type: Northern blot
Annotation Date: 2005-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:3526804
Age: embryonic day 14.5
Image: 2
Specimen Label: KO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6382940
Assay Type: RT-PCR
Annotation Date: 2020-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6383065
Age: postnatal week 1
Image: 5
Specimen Label: 1w Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6382940
Assay Type: RT-PCR
Annotation Date: 2020-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6383065
Age: postnatal week 1
Image: 5
Specimen Label: 1w Cnot3LKO
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6382940
Assay Type: RT-PCR
Annotation Date: 2020-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6383065
Age: postnatal week 4
Image: 5
Specimen Label: 4w Control
Detected: true
Specimen Num: 3
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•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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