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Search results 1 to 100 out of 223 for Irgm1

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Hits by Strain

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Type Details Score
Protein
A0A1G5SJJ3
Organism: Mus musculus/domesticus
Length: 409  
Fragment?: false
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Protein Coding Gene
MGI:107567 | Irgm1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33510463 | J:305209
First Author: Rai P
Year: 2021
Journal: Nat Immunol
Title: IRGM1 links mitochondrial quality control to autoimmunity.
Volume: 22
Issue: 3
Pages: 312-321
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Publication
32311672 | J:303514
 
First Author: Zhang L
Year: 2020
Journal: Int Immunopharmacol
Title: Irgm1 knockout indirectly inhibits regeneration after skeletal muscle injury in mice.
Volume: 84
Pages: 106515
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Publication
17982087 | J:153857
First Author: Henry SC
Year: 2007
Journal: J Immunol
Title: Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47).
Volume: 179
Issue: 10
Pages: 6963-72
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Publication
21633090 | J:176943
First Author: King KY
Year: 2011
Journal: Blood
Title: Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling.
Volume: 118
Issue: 6
Pages: 1525-33
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Publication
27439214 | J:318620
 
First Author: Fang S
Year: 2016
Journal: Atherosclerosis
Title: Irgm1 promotes M1 but not M2 macrophage polarization in atherosclerosis pathogenesis and development.
Volume: 251
Pages: 282-290
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Publication
23689639 | J:207253
 
First Author: Xia F
Year: 2013
Journal: Sci Rep
Title: IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis.
Volume: 3
Pages: 1867
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Publication
20072621 | J:157238
First Author: Zhao YO
Year: 2010
Journal: PLoS One
Title: Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells.
Volume: 5
Issue: 1
Pages: e8648
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Publication
35197566 | J:328106
First Author: Fan Y
Year: 2022
Journal: Cell Death Differ
Title: Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis.
Volume: 29
Issue: 9
Pages: 1673-1688
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Publication
27443879 | J:243244
First Author: Xu Y
Year: 2017
Journal: J Leukoc Biol
Title: Irgm1 is required for the inflammatory function of M1 macrophage in early experimental autoimmune encephalomyelitis.
Volume: 101
Issue: 2
Pages: 507-517
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Publication
18806793 | J:142840
First Author: Feng CG
Year: 2008
Journal: Nat Immunol
Title: The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death.
Volume: 9
Issue: 11
Pages: 1279-87
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Publication
20056715 | J:162368
First Author: Xu H
Year: 2010
Journal: FASEB J
Title: Genetic deficiency of Irgm1 (LRG-47) suppresses induction of experimental autoimmune encephalomyelitis by promoting apoptosis of activated CD4+ T cells.
Volume: 24
Issue: 5
Pages: 1583-92
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Publication
19620982 | J:151541
First Author: Tiwari S
Year: 2009
Journal: Nat Immunol
Title: Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria.
Volume: 10
Issue: 8
Pages: 907-17
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Publication
23842753 | J:205698
First Author: Springer HM
Year: 2013
Journal: J Immunol
Title: Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells.
Volume: 191
Issue: 4
Pages: 1765-74
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Publication
22796503 | J:188154
First Author: Wang C
Year: 2013
Journal: Mol Immunol
Title: Immune-related GTPase Irgm1 exacerbates experimental auto-immune encephalomyelitis by promoting the disruption of blood-brain barrier and blood-cerebrospinal fluid barrier.
Volume: 53
Issue: 1-2
Pages: 43-51
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Publication
16888103 | J:112322
First Author: Singh SB
Year: 2006
Journal: Science
Title: Human IRGM induces autophagy to eliminate intracellular mycobacteria.
Volume: 313
Issue: 5792
Pages: 1438-41
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Publication
23785284 | J:317923
First Author: Haldar AK
Year: 2013
Journal: PLoS Pathog
Title: IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.
Volume: 9
Issue: 6
Pages: e1003414
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Publication
37874678 | J:342325
First Author: Chauhan NR
Year: 2023
Journal: Cell Rep
Title: Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion.
Volume: 42
Issue: 11
Pages: 113275
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Publication
36221902 | J:332005
First Author: Mehto S
Year: 2022
Journal: EMBO J
Title: Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection.
Volume: 41
Issue: 23
Pages: e111289
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Publication
22675202 | J:189560
First Author: Matsuzawa T
Year: 2012
Journal: J Immunol
Title: IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway.
Volume: 189
Issue: 2
Pages: 813-8
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Publication
19920210 | J:157117
First Author: Henry SC
Year: 2010
Journal: J Leukoc Biol
Title: Regulation of macrophage motility by Irgm1.
Volume: 87
Issue: 2
Pages: 333-43
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Publication
34078740 | J:308470
 
First Author: Pradipta A
Year: 2021
Journal: Life Sci Alliance
Title: Cell-autonomous Toxoplasma killing program requires Irgm2 but not its microbe vacuolar localization.
Volume: 4
Issue: 7
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Publication
18424746 | J:134525
First Author: Coers J
Year: 2008
Journal: J Immunol
Title: Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10.
Volume: 180
Issue: 9
Pages: 6237-45
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Publication
33124745 | J:301384
First Author: Finethy R
Year: 2020
Journal: EMBO Rep
Title: Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
Volume: 21
Issue: 11
Pages: e50830
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Publication
34338548 | J:333017
First Author: Dockterman J
Year: 2021
Journal: Infect Immun
Title: Murine Irgm Paralogs Regulate Nonredundant Functions To Execute Host Defense to Toxoplasma gondii.
Volume: 89
Issue: 11
Pages: e0020221
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Publication
32453761 | J:292423
First Author: Taylor GA
Year: 2020
Journal: PLoS Pathog
Title: Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium.
Volume: 16
Issue: 5
Pages: e1008553
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Publication
23989005 | J:210568
First Author: Liu B
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation.
Volume: 305
Issue: 8
Pages: G573-84
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Publication
25644000 | J:229266
First Author: Guo J
Year: 2015
Journal: Infect Immun
Title: IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria.
Volume: 83
Issue: 4
Pages: 1406-17
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Publication
34467632 | J:332983
First Author: Nath P
Year: 2021
Journal: EMBO Rep
Title: Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses.
Volume: 22
Issue: 11
Pages: e52948
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Publication
22874556 | J:329066
First Author: He S
Year: 2012
Journal: Autophagy
Title: Immune-related GTPase M (IRGM1) regulates neuronal autophagy in a mouse model of stroke.
Volume: 8
Issue: 11
Pages: 1621-7
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Publication
19176402 | J:149702
First Author: Henry SC
Year: 2009
Journal: J Leukoc Biol
Title: Balance of Irgm protein activities determines IFN-gamma-induced host defense.
Volume: 85
Issue: 5
Pages: 877-85
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Publication
28154172 | J:241380
First Author: Schmidt EA
Year: 2017
Journal: J Biol Chem
Title: Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages.
Volume: 292
Issue: 11
Pages: 4651-4662
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Publication
22163006 | J:182269
First Author: Chang CP
Year: 2011
Journal: PLoS One
Title: Concanavalin A/IFN-gamma triggers autophagy-related necrotic hepatocyte death through IRGM1-mediated lysosomal membrane disruption.
Volume: 6
Issue: 12
Pages: e28323
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Publication
21757726 | J:176619
First Author: Traver MK
Year: 2011
Journal: J Biol Chem
Title: Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.
Volume: 286
Issue: 35
Pages: 30471-80
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Publication
31612615 | J:328983
First Author: Zhou RX
Year: 2020
Journal: CNS Neurosci Ther
Title: Regulation of hippocampal neuronal apoptosis and autophagy in mice with sepsis-associated encephalopathy by immunity-related GTPase M1.
Volume: 26
Issue: 2
Pages: 177-188
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Publication
36580725 | J:344483
 
First Author: Sun S
Year: 2023
Journal: Biomed Pharmacother
Title: IRGM/Irgm1 deficiency inhibits neutrophil-platelet interactions and thrombosis in experimental atherosclerosis and arterial injury.
Volume: 158
Pages: 114152
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Publication
24751652 | J:332984
First Author: Henry SC
Year: 2014
Journal: PLoS One
Title: Palmitoylation of the immunity related GTPase, Irgm1: impact on membrane localization and ability to promote mitochondrial fission.
Volume: 9
Issue: 4
Pages: e95021
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Publication
29361512 | J:257085
     
First Author: Rogala AR
Year: 2017
Journal: Dis Model Mech
Title: Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice.
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Publication
27098192 | J:332981
 
First Author: Maric-Biresev J
Year: 2016
Journal: BMC Biol
Title: Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.
Volume: 14
Pages: 33
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Protein Coding Gene
MGP_CAROLIEiJ_G0016256 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018178 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018144 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018147 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_107567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017933 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018043 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018037 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018115 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017304 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017574 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017392 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017097 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
19144319 | J:143718
First Author: Trost M
Year: 2009
Journal: Immunity
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
Volume: 30
Issue: 1
Pages: 143-54
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Publication
15294976 | J:92658
First Author: Martens S
Year: 2004
Journal: J Immunol
Title: Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis.
Volume: 173
Issue: 4
Pages: 2594-606
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Publication
18772884 | J:168299
First Author: Hunn JP
Year: 2008
Journal: EMBO J
Title: Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii.
Volume: 27
Issue: 19
Pages: 2495-509
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
7561525 | J:29047
First Author: Sorace JM
Year: 1995
Journal: J Leukoc Biol
Title: Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family.
Volume: 58
Issue: 4
Pages: 477-84
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Publication
11457893 | J:87535
First Author: Collazo CM
Year: 2001
Journal: J Exp Med
Title: Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection.
Volume: 194
Issue: 2
Pages: 181-8
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Publication
14707092 | J:87364
First Author: Feng CG
Year: 2004
Journal: J Immunol
Title: Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia.
Volume: 172
Issue: 2
Pages: 1163-8
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Publication
15908352 | J:99144
First Author: Butcher BA
Year: 2005
Journal: Infect Immun
Title: p47 GTPases regulate Toxoplasma gondii survival in activated macrophages.
Volume: 73
Issue: 6
Pages: 3278-86
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Publication
16339555 | J:122278
First Author: Santiago HC
Year: 2005
Journal: J Immunol
Title: Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth.
Volume: 175
Issue: 12
Pages: 8165-72
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Publication
17911638 | J:153019
First Author: Bafica A
Year: 2007
Journal: J Immunol
Title: The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflammatory cytokine production and prevents endotoxemia.
Volume: 179
Issue: 8
Pages: 5514-22
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
23853600 | J:213363
First Author: Berghout J
Year: 2013
Journal: PLoS Pathog
Title: Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria.
Volume: 9
Issue: 7
Pages: e1003491
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Publication
34694641 | J:333980
First Author: Christgen S
Year: 2022
Journal: Eur J Immunol
Title: The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.
Volume: 52
Issue: 2
Pages: 285-296
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Publication
21731484 | J:182190
First Author: Coers J
Year: 2011
Journal: PLoS Pathog
Title: Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections.
Volume: 7
Issue: 6
Pages: e1001346
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Publication
26440898 | J:312451
First Author: Lee Y
Year: 2015
Journal: Cell Rep
Title: p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.
Volume: 13
Issue: 2
Pages: 223-33
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Publication
23012479 | J:190322
First Author: Archambaud C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Impact of lactobacilli on orally acquired listeriosis.
Volume: 109
Issue: 41
Pages: 16684-9
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Publication
24715728 | J:208845
First Author: Pilla DM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.
Volume: 111
Issue: 16
Pages: 6046-51
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Publication
25482432 | J:268956
First Author: Sun L
Year: 2015
Journal: Cell Host Microbe
Title: Type I interferons link viral infection to enhanced epithelial turnover and repair.
Volume: 17
Issue: 1
Pages: 85-97
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Publication
28193861 | J:241213
First Author: Feeley EM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems.
Volume: 114
Issue: 9
Pages: E1698-E1706
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Publication
17082622 | J:140485
First Author: Koga R
Year: 2006
Journal: J Immunol
Title: TLR-dependent induction of IFN-beta mediates host defense against Trypanosoma cruzi.
Volume: 177
Issue: 10
Pages: 7059-66
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Publication
18371424 | J:149806
First Author: Feng CG
Year: 2008
Journal: Cell Stem Cell
Title: The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation.
Volume: 2
Issue: 1
Pages: 83-9
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Publication
21383050 | J:171938
First Author: von Bargen K
Year: 2011
Journal: Infect Immun
Title: Nitric oxide-mediated intracellular growth restriction of pathogenic Rhodococcus equi can be prevented by iron.
Volume: 79
Issue: 5
Pages: 2098-111
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Publication
32715615 | J:298776
First Author: Jena KK
Year: 2020
Journal: EMBO Rep
Title: Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response.
Volume: 21
Issue: 9
Pages: e50051
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Publication
23132496 | J:190883
First Author: Tischler AD
Year: 2013
Journal: Infect Immun
Title: Mycobacterium tuberculosis requires phosphate-responsive gene regulation to resist host immunity.
Volume: 81
Issue: 1
Pages: 317-28
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Publication
35941154 | J:327605
First Author: Chandrasekaran S
Year: 2022
Journal: Nat Commun
Title: IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii.
Volume: 13
Issue: 1
Pages: 4605
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Publication
20566858 | J:162073
First Author: Dhar N
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice.
Volume: 107
Issue: 27
Pages: 12275-80
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Publication
32542357 | J:301395
First Author: Norona J
Year: 2020
Journal: Blood
Title: Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans.
Volume: 136
Issue: 12
Pages: 1442-1455
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Publication
31648279 | J:285422
First Author: Tuladhar S
Year: 2019
Journal: PLoS Pathog
Title: The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
Volume: 15
Issue: 10
Pages: e1007856
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Publication
30612879 | J:271759
First Author: Mehto S
Year: 2019
Journal: Mol Cell
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