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Search results 1 to 100 out of 1068 for Itch

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Marino A
Year: 2014
Journal: Diabetes
Title: ITCH deficiency protects from diet-induced obesity.
Volume: 63
Issue: 2
Pages: 550-61
Publication
First Author: Kathania M
Year: 2015
Journal: J Immunol
Title: Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7.
Volume: 194
Issue: 5
Pages: 2160-7
Publication
First Author: Moser EK
Year: 2019
Journal: J Exp Med
Title: The E3 ubiquitin ligase Itch restricts antigen-driven B cell responses.
Volume: 216
Issue: 9
Pages: 2170-2183
Publication
First Author: Kathania M
Year: 2016
Journal: Nat Immunol
Title: Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-γt ubiquitination.
Volume: 17
Issue: 8
Pages: 997-1004
Publication
First Author: Hansen TM
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Itch inhibition regulates chemosensitivity in vitro.
Volume: 361
Issue: 1
Pages: 33-6
Publication
First Author: Rossi M
Year: 2005
Journal: EMBO J
Title: The ubiquitin-protein ligase Itch regulates p73 stability.
Volume: 24
Issue: 4
Pages: 836-48
Publication
First Author: Zhang H
Year: 2013
Journal: Stem Cells
Title: Ubiquitin e3 ligase itch negatively regulates osteoblast differentiation from mesenchymal progenitor cells.
Volume: 31
Issue: 8
Pages: 1574-83
Publication
First Author: Bai Y
Year: 2004
Journal: Mol Cell
Title: Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation.
Volume: 15
Issue: 5
Pages: 825-31
Publication
First Author: Matesic LE
Year: 2006
Journal: Hum Mol Genet
Title: Itch genetically interacts with Notch1 in a mouse autoimmune disease model.
Volume: 15
Issue: 24
Pages: 3485-97
Publication
First Author: Giamboi-Miraglia A
Year: 2015
Journal: FEBS J
Title: The E3 ligase Itch knockout mice show hyperproliferation and wound healing alteration.
Volume: 282
Issue: 23
Pages: 4435-49
Publication
First Author: Rathinam C
Year: 2011
Journal: Nat Immunol
Title: The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic stem cells.
Volume: 12
Issue: 5
Pages: 399-407
Publication  
First Author: Stöhr R
Year: 2015
Journal: Sci Rep
Title: ITCH modulates SIRT6 and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE null mice.
Volume: 5
Pages: 9023
Publication
First Author: Fang D
Year: 2002
Journal: Nat Immunol
Title: Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.
Volume: 3
Issue: 3
Pages: 281-7
Publication
First Author: Ahmed N
Year: 2011
Journal: Nat Immunol
Title: The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.
Volume: 12
Issue: 12
Pages: 1176-83
Publication
First Author: Liu X
Year: 2019
Journal: Sci Rep
Title: The E3 ubiquitin ligase Itch is required for B-cell development.
Volume: 9
Issue: 1
Pages: 421
Publication
First Author: Zhang H
Year: 2013
Journal: J Biol Chem
Title: Ubiquitin E3 ligase Itch negatively regulates osteoclast formation by promoting deubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6.
Volume: 288
Issue: 31
Pages: 22359-68
Publication
First Author: Theivanthiran B
Year: 2015
Journal: Sci Signal
Title: The E3 ubiquitin ligase Itch inhibits p38α signaling and skin inflammation through the ubiquitylation of Tab1.
Volume: 8
Issue: 365
Pages: ra22
Publication
First Author: Enzler T
Year: 2009
Journal: J Immunol
Title: MEKK1 binds HECT E3 ligase Itch by its amino-terminal RING motif to regulate Th2 cytokine gene expression.
Volume: 183
Issue: 6
Pages: 3831-8
Publication
First Author: Lee TL
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Itch regulates p45/NF-E2 in vivo by Lys63-linked ubiquitination.
Volume: 375
Issue: 3
Pages: 326-30
Publication
First Author: Chang L
Year: 2006
Journal: Cell
Title: The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover.
Volume: 124
Issue: 3
Pages: 601-13
Publication
First Author: Xiao N
Year: 2014
Journal: Nat Immunol
Title: The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells.
Volume: 15
Issue: 7
Pages: 657-66
Publication
First Author: Shembade N
Year: 2008
Journal: Nat Immunol
Title: The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20.
Volume: 9
Issue: 3
Pages: 254-62
Publication
First Author: Jin HS
Year: 2013
Journal: J Clin Invest
Title: Itch expression by Treg cells controls Th2 inflammatory responses.
Volume: 123
Issue: 11
Pages: 4923-34
Publication
First Author: Tao M
Year: 2009
Journal: Curr Biol
Title: ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.
Volume: 19
Issue: 15
Pages: 1255-63
Publication
First Author: Venuprasad K
Year: 2008
Journal: Nat Immunol
Title: The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1.
Volume: 9
Issue: 3
Pages: 245-53
Publication
First Author: Fang Y
Year: 2021
Journal: Eur J Immunol
Title: The E3 ubiquitin ligase Itch deficiency promotes antigen-driven B-cell responses in mice.
Volume: 51
Issue: 1
Pages: 103-114
Publication
First Author: Kim Y
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability.
Volume: 114
Issue: 18
Pages: 4691-4696
Publication
First Author: Wei W
Year: 2012
Journal: Mol Cell Biol
Title: The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein.
Volume: 32
Issue: 19
Pages: 3903-12
Publication
First Author: Oliver PM
Year: 2006
Journal: Immunity
Title: Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation.
Volume: 25
Issue: 6
Pages: 929-40
Publication
First Author: Aki D
Year: 2018
Journal: Nat Immunol
Title: The E3 ligases Itch and WWP2 cooperate to limit TH2 differentiation by enhancing signaling through the TCR.
Volume: 19
Issue: 7
Pages: 766-775
Publication
First Author: ZeRuth GT
Year: 2015
Journal: PLoS One
Title: HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity.
Volume: 10
Issue: 7
Pages: e0131303
Publication
First Author: Perry WL
Year: 1998
Journal: Nat Genet
Title: The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice.
Volume: 18
Issue: 2
Pages: 143-6
Publication
First Author: Perez JM
Year: 2015
Journal: Cell Rep
Title: An IκB Kinase-Regulated Feedforward Circuit Prolongs Inflammation.
Volume: 12
Issue: 4
Pages: 537-44
Publication
First Author: Paul J
Year: 2018
Journal: Mucosal Immunol
Title: IL-17-driven intestinal fibrosis is inhibited by Itch-mediated ubiquitination of HIC-5.
Volume: 11
Issue: 2
Pages: 427-436
Publication
First Author: Huang H
Year: 2010
Journal: Immunity
Title: K33-linked polyubiquitination of T cell receptor-zeta regulates proteolysis-independent T cell signaling.
Volume: 33
Issue: 1
Pages: 60-70
Publication
First Author: Parravicini V
Year: 2008
Journal: Blood
Title: Itch-/- alphabeta and gammadelta T cells independently contribute to autoimmunity in Itchy mice.
Volume: 111
Issue: 8
Pages: 4273-7282
Publication
First Author: Venuprasad K
Year: 2006
Journal: J Clin Invest
Title: Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation.
Volume: 116
Issue: 4
Pages: 1117-26
Publication
First Author: Heissmeyer V
Year: 2004
Journal: Nat Immunol
Title: Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins.
Volume: 5
Issue: 3
Pages: 255-65
Publication
First Author: Lin X
Year: 2020
Journal: J Biol Chem
Title: Ubiquitination of interleukin-1α is associated with increased pro-inflammatory polarization of murine macrophages deficient in the E3 ligase ITCH.
Volume: 295
Issue: 33
Pages: 11764-11775
Publication
First Author: Mathews TA
Year: 2004
Journal: J Neurosci Methods
Title: Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression.
Volume: 140
Issue: 1-2
Pages: 169-81
Publication
First Author: Hustad CM
Year: 1995
Journal: Genetics
Title: Molecular genetic characterization of six recessive viable alleles of the mouse agouti locus.
Volume: 140
Issue: 1
Pages: 255-65
Publication
First Author: Sakurai T
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation.
Volume: 103
Issue: 28
Pages: 10544-51
Publication
First Author: Mössinger J
Year: 2012
Journal: EMBO Rep
Title: Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch.
Volume: 13
Issue: 12
Pages: 1087-94
Publication
First Author: Ramos-Hernández N
Year: 2013
Journal: J Immunol
Title: Ndfip1 enforces a requirement for CD28 costimulation by limiting IL-2 production.
Volume: 191
Issue: 4
Pages: 1536-46
Publication
First Author: Zhang WC
Year: 2019
Journal: Cell Cycle
Title: miR-34b/c regulates doxorubicin-induced myocardial cell injury through ITCH.
Volume: 18
Issue: 23
Pages: 3263-3274
Publication
First Author: Ahn YH
Year: 2009
Journal: J Biol Chem
Title: MKK4/SEK1 is negatively regulated through a feedback loop involving the E3 ubiquitin ligase itch.
Volume: 284
Issue: 43
Pages: 29399-404
Publication
First Author: Oberst A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch.
Volume: 104
Issue: 27
Pages: 11280-5
Publication
First Author: Hoff H
Year: 2010
Journal: Mol Immunol
Title: CTLA-4 (CD152) inhibits T cell function by activating the ubiquitin ligase Itch.
Volume: 47
Issue: 10
Pages: 1875-81
Publication
First Author: Tigno-Aranjuez JT
Year: 2013
Journal: Mol Cell Biol
Title: A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.
Volume: 33
Issue: 1
Pages: 146-58
Publication
First Author: Infante P
Year: 2018
Journal: Nat Commun
Title: Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Volume: 9
Issue: 1
Pages: 976
Publication
First Author: Chastagner P
Year: 2008
Journal: PLoS One
Title: AIP4/Itch regulates Notch receptor degradation in the absence of ligand.
Volume: 3
Issue: 7
Pages: e2735
Publication  
First Author: Choi YB
Year: 2017
Journal: Mol Cell Biol
Title: TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS.
Volume: 37
Issue: 1
Publication
First Author: Traweger A
Year: 2002
Journal: J Biol Chem
Title: The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase itch.
Volume: 277
Issue: 12
Pages: 10201-8
Publication
First Author: Sapir T
Year: 2018
Journal: Cereb Cortex
Title: Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases.
Volume: 28
Issue: 9
Pages: 3115-3128
Publication
First Author: Shembade N
Year: 2011
Journal: Nat Immunol
Title: The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1.
Volume: 12
Issue: 9
Pages: 834-43
Publication
First Author: Premarathne S
Year: 2017
Journal: Sci Rep
Title: Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors.
Volume: 7
Issue: 1
Pages: 8109
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: SoRelle J
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for scratch
Publication
First Author: Zhang M
Year: 2007
Journal: J Immunol
Title: Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor.
Volume: 179
Issue: 7
Pages: 4435-43
Publication
First Author: Kathania M
Year: 2020
Journal: J Immunol
Title: Gut Microbiota Contributes to Spontaneous Colitis in E3 Ligase Itch-Deficient Mice.
Volume: 204
Issue: 8
Pages: 2277-2284
GXD Expression    
Probe: MGI:2667142
Assay Type: Western blot
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:2667148
Age: embryonic day 13.0
Image: 3
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2667142
Assay Type: Western blot
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:2667150
Age: embryonic day 13.0
Image: 3
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4416300
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825634
Age: embryonic day 14.5
Image: euxassay_009772_19
Detected: true
Specimen Num: 19