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Search results 1 to 100 out of 321 for Itga2b

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Basani RB
Year: 2009
Journal: Blood
Title: Species differences in small molecule binding to alpha IIb beta 3 are the result of sequence differences in 2 loops of the alpha IIb beta propeller.
Volume: 113
Issue: 4
Pages: 902-10
Publication
First Author: Emambokus NR
Year: 2003
Journal: Immunity
Title: The glycoprotein IIb molecule is expressed on early murine hematopoietic progenitors and regulates their numbers in sites of hematopoiesis.
Volume: 19
Issue: 1
Pages: 33-45
Publication
First Author: Thornton MA
Year: 2002
Journal: Blood
Title: Identification of distal regulatory regions in the human alpha IIb gene locus necessary for consistent, high-level megakaryocyte expression.
Volume: 100
Issue: 10
Pages: 3588-96
Publication
First Author: Berlanga O
Year: 2005
Journal: Exp Hematol
Title: GPIIb (CD41) integrin is expressed on mast cells and influences their adhesion properties.
Volume: 33
Issue: 4
Pages: 403-12
Publication
First Author: Echtler K
Year: 2017
Journal: PLoS One
Title: Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis.
Volume: 12
Issue: 3
Pages: e0172788
Publication
First Author: Echtler K
Year: 2010
Journal: Nat Med
Title: Platelets contribute to postnatal occlusion of the ductus arteriosus.
Volume: 16
Issue: 1
Pages: 75-82
Publication
First Author: Alshehri OM
Year: 2015
Journal: Blood
Title: Fibrin activates GPVI in human and mouse platelets.
Volume: 126
Issue: 13
Pages: 1601-8
Publication
First Author: Suzuki A
Year: 2013
Journal: PLoS One
Title: RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation.
Volume: 8
Issue: 7
Pages: e69315
Publication
First Author: Massberg S
Year: 2005
Journal: Circulation
Title: Platelet adhesion via glycoprotein IIb integrin is critical for atheroprogression and focal cerebral ischemia: an in vivo study in mice lacking glycoprotein IIb.
Volume: 112
Issue: 8
Pages: 1180-8
Publication
First Author: Oki T
Year: 2009
Journal: J Biol Chem
Title: Evidence that integrin alpha IIb beta 3-dependent interaction of mast cells with fibrinogen exacerbates chronic inflammation.
Volume: 284
Issue: 45
Pages: 31463-72
Publication
First Author: Gaertner F
Year: 2017
Journal: Cell
Title: Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria.
Volume: 171
Issue: 6
Pages: 1368-1382.e23
Publication
First Author: Larson MK
Year: 2006
Journal: Blood
Title: Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3.
Volume: 108
Issue: 5
Pages: 1509-14
Publication
First Author: Liakhovitskaia A
Year: 2014
Journal: Development
Title: Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this.
Volume: 141
Issue: 17
Pages: 3319-23
Publication
First Author: Lowe KL
Year: 2015
Journal: Blood
Title: Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development.
Volume: 125
Issue: 24
Pages: 3769-77
Publication
First Author: Chang YS
Year: 1999
Journal: Mamm Genome
Title: Conservation of the linkage of the murine Itga2b and Itgb3 loci in mouse chromosome 11.
Volume: 10
Issue: 5
Pages: 530-1
Allele
Name: transgene insertion A, Roberto Parrilla
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Itga2b-cre)AParl/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Nowakowski A
Year: 2011
Journal: Thromb Haemost
Title: Megakaryocyte gene targeting mediated by restricted expression of recombinase Cre.
Volume: 105
Issue: 1
Pages: 138-44
Allele
Name: transgene insertion NE1/21, Nikla R Emambokus
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Allele
Name: integrin alpha 2b; targeted mutation 1, Nikla R Emambokus
Allele Type: Targeted
Attribute String: Null/knockout, Recombinase
Publication categories: ProxyCollection
Genotype
Symbol: Itga2b/Itga2b
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Itga2b-cre)NE1/21Emam/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Itga2b/Itga2b Rhoa/Rhoa Tg(ITGA2B)3Mako/? Tg(Pf4-icre)Q3Rsko/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Itga2b-cre)NE1/21Emam/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Tronik-Le Roux D
Year: 2000
Journal: Blood
Title: Thrombasthenic mice generated by replacement of the integrin alpha(IIb) gene: demonstration that transcriptional activation of this megakaryocytic locus precedes lineage commitment.
Volume: 96
Issue: 4
Pages: 1399-408
Publication
First Author: Chen J
Year: 2008
Journal: Nat Biotechnol
Title: Modifying murine von Willebrand factor A1 domain for in vivo assessment of human platelet therapies.
Volume: 26
Issue: 1
Pages: 114-9
Publication
First Author: Boisset JC
Year: 2013
Journal: Biol Open
Title: Integrin ╬▒IIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta.
Volume: 2
Issue: 5
Pages: 525-32
Publication
First Author: Cordeiro OG
Year: 2016
Journal: PLoS One
Title: Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL.
Volume: 11
Issue: 3
Pages: e0151848
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Thornton MA
Year: 1999
Journal: Blood
Title: Characterization of the murine platelet alphaIIb gene and encoded cDNA.
Volume: 94
Issue: 11
Pages: 3947-50
Publication  
First Author: Deppermann C
Year: 2020
Journal: J Exp Med
Title: Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets.
Volume: 217
Issue: 4
Publication
First Author: Gekas C
Year: 2013
Journal: Blood
Title: CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age.
Volume: 121
Issue: 22
Pages: 4463-72
Publication
First Author: Wong CH
Year: 2013
Journal: Nat Immunol
Title: Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance.
Volume: 14
Issue: 8
Pages: 785-92
Publication
First Author: Zhang J
Year: 2007
Journal: Exp Hematol
Title: CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation.
Volume: 35
Issue: 3
Pages: 490-499
Publication
First Author: Gaines P
Year: 2000
Journal: J Biol Chem
Title: GATA-1- and FOG-dependent activation of megakaryocytic alpha IIB gene expression.
Volume: 275
Issue: 44
Pages: 34114-21
Publication
First Author: Denarier E
Year: 1993
Journal: Biochem Biophys Res Commun
Title: PCR cloning and sequence of the murine GPIIb gene promoter.
Volume: 195
Issue: 3
Pages: 1360-4
Publication
First Author: Robin C
Year: 2011
Journal: Blood
Title: CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells.
Volume: 117
Issue: 19
Pages: 5088-91
GXD Expression      
Probe: MGI:3802998
Assay Type: RT-PCR
Annotation Date: 2008-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:3803179
Age: embryonic day 9.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3802998
Assay Type: RT-PCR
Annotation Date: 2008-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:3803179
Age: embryonic day 9.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3802998
Assay Type: RT-PCR
Annotation Date: 2008-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608517
Stage: TS17
Assay Id: MGI:3803179
Age: embryonic day 10.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3802998
Assay Type: RT-PCR
Annotation Date: 2008-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608517
Stage: TS17
Assay Id: MGI:3803179
Age: embryonic day 10.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3802998
Assay Type: RT-PCR
Annotation Date: 2008-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608519
Stage: TS19
Assay Id: MGI:3803179
Age: embryonic day 11.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3802998
Assay Type: RT-PCR
Annotation Date: 2008-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608519
Stage: TS19
Assay Id: MGI:3803179
Age: embryonic day 11.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2652159
Assay Type: RT-PCR
Annotation Date: 2003-03-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2652243
Age: embryonic day 11.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652159
Assay Type: RT-PCR
Annotation Date: 2003-03-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2652243
Age: embryonic day 11.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652159
Assay Type: RT-PCR
Annotation Date: 2003-03-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2652243
Age: embryonic day 11.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2652159
Assay Type: RT-PCR
Annotation Date: 2003-03-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2652258
Age: embryonic day 11.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2652159
Assay Type: RT-PCR
Annotation Date: 2003-03-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2652258
Age: embryonic day 11.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2652159
Assay Type: RT-PCR
Annotation Date: 2003-03-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2652258
Age: embryonic day 11.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6161618
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6161631
Age: embryonic day 11.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6161618
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6161631
Age: embryonic day 11.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6161618
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6161633
Age: embryonic day 11.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6161618
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6161633
Age: embryonic day 11.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1328833
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:1328974
Age: embryonic day 2.0
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1328833
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:1328974
Age: embryonic day 2.0
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3802998
Assay Type: RT-PCR
Annotation Date: 2008-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:3803179
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6161618
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:6161634
Age: embryonic day 12.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6161618
Assay Type: RT-PCR
Annotation Date: 2018-06-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:6161634
Age: embryonic day 12.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4401990
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:6414605
Age: embryonic day 14.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4401990
Assay Type: Northern blot
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:6414605
Age: embryonic day 14.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1328833
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:1328974
Age: embryonic day 1.0
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1328833
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:1328974
Age: embryonic day 1.0
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1328833
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:1328974
Age: embryonic day 4.0
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:1328833
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:1328974
Age: embryonic day 4.0
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:1328833
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:1328974
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1328833
Assay Type: RT-PCR
Annotation Date: 1999-02-08
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:1328974
Age: postnatal adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5784650
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5784659
Age: embryonic day 9.5
Note: Expression in diploid platelet-forming cells in the placental vasculature.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5784650
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5784659
Age: embryonic day 10.5
Note: Expression in diploid platelet-forming cells in the placental vasculature.
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5784650
Assay Type: Immunohistochemistry
Annotation Date: 2016-07-26
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3568928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5784662
Age: embryonic day 8.5
Note: Expression in hematopoietic cells distributed within clusters of the post-chorioallantoic fusion placenta.
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5506566
Assay Type: Immunohistochemistry
Annotation Date: 2013-09-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3291016
Pattern: Clusters
Stage: TS16
Assay Id: MGI:5506569
Age: embryonic day 10.0
Image: 1A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2679310
Assay Type: Immunohistochemistry
Annotation Date: 2003-11-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1605811
Stage: TS11
Assay Id: MGI:2679370
Age: embryonic day 7.25
Image: 3G & I
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:6407078
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1633222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6407116
Age: embryonic day 14.5
Note: Expressed in platelets with Ly76+ red cells in blood vessels and in both the ventricles and parenchyma.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6407078
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1633222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6407116
Age: embryonic day 14.5
Note: Expressed in platelets in blood vessels.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2679310
Assay Type: Immunohistochemistry
Annotation Date: 2003-11-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1608510
Pattern: Regionally restricted
Stage: TS10
Assay Id: MGI:2679370
Age: embryonic day 7.0
Image: 3A & C
Note: Expression was detected at the proximal end of the yolk sac.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2679310
Assay Type: Immunohistochemistry
Annotation Date: 2003-11-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1608511
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:2679370
Age: embryonic day 7.25
Image: 3D & F
Note: Expression was detected in a 5-10 cell diameter wide band of cells in the proximal portion of the yolk sac overlying the upper exocoelomic cavity.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:2679310
Assay Type: Immunohistochemistry
Annotation Date: 2003-11-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1608511
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:2679370
Age: embryonic day 7.25
Image: 3G & I
Note: Expression varied from weak to trace in the proximal yolk sac.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:2679310
Assay Type: Immunohistochemistry
Annotation Date: 2003-11-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1608511
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:2679370
Age: embryonic day 7.5
Image: 3J
Note: Expression was detected in the proximal yolk sac.
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:2679310
Assay Type: Immunohistochemistry
Annotation Date: 2003-11-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1608511
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:2679370
Age: embryonic day 7.5
Image: 3K & M
Note: Expression was detected in a 5-10 cells wide, 1-2 cells thick band of cells that was visible around the full circumference of the yolk sac.
Detected: true
Specimen Num: 5