Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Glawe JD |
Year: |
2009 |
Journal: |
Diabetes |
Title: |
Genetic deficiency of Itgb2 or ItgaL prevents autoimmune diabetes through distinctly different mechanisms in NOD/LtJ mice. |
Volume: |
58 |
Issue: |
6 |
Pages: |
1292-301 |
|
•
•
•
•
•
|
Publication |
First Author: |
Keum S |
Year: |
2013 |
Journal: |
PLoS Genet |
Title: |
Natural genetic variation of integrin alpha L (Itgal) modulates ischemic brain injury in stroke. |
Volume: |
9 |
Issue: |
10 |
Pages: |
e1003807 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith CM |
Year: |
2019 |
Journal: |
mBio |
Title: |
Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice. |
Volume: |
10 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2019 |
Journal: |
Infect Immun |
Title: |
A Loss-of-Function Mutation in the Integrin Alpha L (Itgal) Gene Contributes to Susceptibility to Salmonella enterica Serovar Typhimurium Infection in Collaborative Cross Strain CC042. |
Volume: |
88 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1162
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1161
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang E |
Year: |
2014 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Essential role of CD11a in CD8+ T-cell accumulation and activation in adipose tissue. |
Volume: |
34 |
Issue: |
1 |
Pages: |
34-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bose TO |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
CD11a is essential for normal development of hematopoietic intermediates. |
Volume: |
193 |
Issue: |
6 |
Pages: |
2863-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmits R |
Year: |
1996 |
Journal: |
J Exp Med |
Title: |
LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor. |
Volume: |
183 |
Issue: |
4 |
Pages: |
1415-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsumoto G |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Essential role of the adhesion receptor LFA-1 for T cell-dependent fulminant hepatitis. |
Volume: |
169 |
Issue: |
12 |
Pages: |
7087-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2008 |
Journal: |
Int Immunol |
Title: |
LFA-1 decreases the antigen dose for T cell activation in vivo. |
Volume: |
20 |
Issue: |
9 |
Pages: |
1119-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2007 |
Journal: |
Biochem Biophys Res Commun |
Title: |
A critical role of LFA-1 in the development of Th17 cells and induction of experimental autoimmune encephalomyelytis. |
Volume: |
353 |
Issue: |
4 |
Pages: |
857-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schramm R |
Year: |
2007 |
Journal: |
Immunology |
Title: |
Statins inhibit lymphocyte homing to peripheral lymph nodes. |
Volume: |
120 |
Issue: |
3 |
Pages: |
315-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Emoto M |
Year: |
2000 |
Journal: |
Eur J Immunol |
Title: |
Participation of leukocyte function-associated antigen-1 and NK cells in the homing of thymic CD8+NKT cells to the liver. |
Volume: |
30 |
Issue: |
10 |
Pages: |
3049-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsumoto G |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
Essential role of LFA-1 in activating Th2-like responses by alpha-galactosylceramide-activated NKT cells. |
Volume: |
173 |
Issue: |
8 |
Pages: |
4976-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berlin-Rufenach C |
Year: |
1999 |
Journal: |
J Exp Med |
Title: |
Lymphocyte migration in lymphocyte function-associated antigen (LFA)-1-deficient mice. |
Volume: |
189 |
Issue: |
9 |
Pages: |
1467-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Henderson RB |
Year: |
2001 |
Journal: |
J Exp Med |
Title: |
The use of lymphocyte function-associated antigen (LFA)-1-deficient mice to determine the role of LFA-1, Mac-1, and alpha4 integrin in the inflammatory response of neutrophils. |
Volume: |
194 |
Issue: |
2 |
Pages: |
219-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frommhold D |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Protein C concentrate controls leukocyte recruitment during inflammation and improves survival during endotoxemia after efficient in vivo activation. |
Volume: |
179 |
Issue: |
5 |
Pages: |
2637-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Semmrich M |
Year: |
2005 |
Journal: |
J Exp Med |
Title: |
Importance of integrin LFA-1 deactivation for the generation of immune responses. |
Volume: |
201 |
Issue: |
12 |
Pages: |
1987-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park EJ |
Year: |
2010 |
Journal: |
Blood |
Title: |
Distinct roles for LFA-1 affinity regulation during T-cell adhesion, diapedesis, and interstitial migration in lymph nodes. |
Volume: |
115 |
Issue: |
8 |
Pages: |
1572-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hogarth PM |
Year: |
1985 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The Ly-15 alloantigenic system: a genetically determined polymorphism of the murine lymphocyte function-associated antigen-1 molecule. |
Volume: |
82 |
Issue: |
2 |
Pages: |
526-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hogarth PM |
Year: |
1986 |
Journal: |
Immunogenetics |
Title: |
Mapping of the murine Ly-15 (LFA-1) locus to chromosome 7. |
Volume: |
23 |
Issue: |
5 |
Pages: |
348-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hogarth PM |
Year: |
1992 |
Journal: |
Immunogenetics |
Title: |
Ly-15.2 and Ly-21.2 are distinct polymorphisms of the LFA-1 heavy chain. |
Volume: |
36 |
Issue: |
6 |
Pages: |
396-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quddus J |
Year: |
1994 |
Journal: |
Immunology |
Title: |
Anti-CD11a prevents deletion of self-reactive T cells in neonatal C57BR mice. |
Volume: |
82 |
Issue: |
2 |
Pages: |
301-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Champe M |
Year: |
1995 |
Journal: |
J Biol Chem |
Title: |
Monoclonal antibodies that block the activity of leukocyte function-associated antigen 1 recognize three discrete epitopes in the inserted domain of CD11a. |
Volume: |
270 |
Issue: |
3 |
Pages: |
1388-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cabañas C |
Year: |
1999 |
Journal: |
J Biol Regul Homeost Agents |
Title: |
CD11a (leukocyte integrin LFA-1 alpha subunit). |
Volume: |
13 |
Issue: |
2 |
Pages: |
126-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Graf B |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapse. |
Volume: |
179 |
Issue: |
3 |
Pages: |
1616-24 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5637839 |
Assay Type: |
RT-PCR |
Annotation Date: |
2015-06-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610521 |
|
Stage: |
TS21 |
Assay Id: |
MGI:5637963 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
4 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6380028 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-12-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1901626 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6380111 |
Age: |
embryonic day 18.5 |
Image: |
6 |
|
Specimen Label: |
Fb |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6380028 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-12-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1871526 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6380111 |
Age: |
embryonic day 18.5 |
Image: |
6 |
|
Specimen Label: |
Pb |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5637943 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1786821 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:5638111 |
Age: |
embryonic day 13.5 |
|
Note: |
Expressed in the endothelial cells of the AV canal cushion. |
Specimen Label: |
3B |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5637943 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268819 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:5638111 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
3A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5637943 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5638111 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
3B |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423553 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4825649 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009583_12 |
|
Specimen Label: |
euxassay_009583_12 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423553 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4825649 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009583_13 |
|
Specimen Label: |
euxassay_009583_13 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423553 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4825649 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009583_14 |
|
Specimen Label: |
euxassay_009583_14 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423553 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4825649 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009583_15 |
|
Specimen Label: |
euxassay_009583_15 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5637943 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268619 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5638111 |
Age: |
embryonic day 11.5 |
|
Note: |
Expressed in the endothelial cells of the AV canal cushion. |
Specimen Label: |
3A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5637943 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5638111 |
Age: |
postnatal month 1 |
|
|
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5637943 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3643819 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5638111 |
Age: |
embryonic day 11.5 |
|
Note: |
Expressed in the mesenchymal cells inside the cardiac jelly. |
Specimen Label: |
3A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5637943 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3643821 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:5638111 |
Age: |
embryonic day 13.5 |
|
Note: |
Expressed in the mesenchymal cells inside the cardiac jelly. |
Specimen Label: |
3B |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lefebvre MN |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
Expeditious recruitment of circulating memory CD8 TÂ cells to the liver facilitates control of malaria. |
Volume: |
37 |
Issue: |
5 |
Pages: |
109956 |
|
•
•
•
•
•
|
Publication |
First Author: |
Byeseda SE |
Year: |
2009 |
Journal: |
Am J Pathol |
Title: |
ICAM-1 is necessary for epithelial recruitment of gammadelta T cells and efficient corneal wound healing. |
Volume: |
175 |
Issue: |
2 |
Pages: |
571-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
1997 |
Journal: |
J Exp Med |
Title: |
Essential lymphocyte function associated 1 (LFA-1): intercellular adhesion molecule interactions for T cell-mediated B cell apoptosis by Fas/APO-1/CD95. |
Volume: |
186 |
Issue: |
7 |
Pages: |
1171-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marvin MR |
Year: |
1998 |
Journal: |
J Surg Res |
Title: |
Liver metastases are enhanced in homozygous deletionally mutant ICAM-1 or LFA-1 mice. |
Volume: |
80 |
Issue: |
2 |
Pages: |
143-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Engels R |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
LFA1 and ICAM1 are critical for fusion and spread of murine leukemia virus in vivo. |
Volume: |
38 |
Issue: |
3 |
Pages: |
110279 |
|
•
•
•
•
•
|
Publication |
First Author: |
Katakai T |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Dendritic cells regulate high-speed interstitial T cell migration in the lymph node via LFA-1/ICAM-1. |
Volume: |
191 |
Issue: |
3 |
Pages: |
1188-99 |
|
•
•
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