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Search results 1 to 100 out of 1145 for Itgam

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0.043s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Yamazaki T
Year: 2017
Journal: Cell Rep
Title: Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature.
Volume: 18
Issue: 12
Pages: 2991-3004
Publication
First Author: Avery JT
Year: 2019
Journal: Mamm Genome
Title: Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferation.
Volume: 30
Issue: 9-10
Pages: 245-259
Allele
Name: transgene insertion B, Jean Vacher
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Allele
Name: transgene insertion A, Jean Vacher
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Otero JE
Year: 2008
Journal: J Biol Chem
Title: Defective osteoclastogenesis by IKKbeta-null precursors is a result of receptor activator of NF-kappaB ligand (RANKL)-induced JNK-dependent apoptosis and impaired differentiation.
Volume: 283
Issue: 36
Pages: 24546-53
Genotype
Symbol: Ctsk/Ctsk Tg(Itgam-cre)AJva/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Ferron M
Year: 2005
Journal: Genesis
Title: Targeted expression of Cre recombinase in macrophages and osteoclasts in transgenic mice.
Volume: 41
Issue: 3
Pages: 138-45
Publication
First Author: Soung do Y
Year: 2014
Journal: Mol Endocrinol
Title: Runx1-mediated regulation of osteoclast differentiation and function.
Volume: 28
Issue: 4
Pages: 546-53
Publication  
First Author: Fukasawa K
Year: 2016
Journal: Sci Rep
Title: ATF3 controls proliferation of osteoclast precursor and bone remodeling.
Volume: 6
Pages: 30918
Publication
First Author: Yuan X
Year: 2015
Journal: Cell Death Differ
Title: Regulators of G protein signaling 12 promotes osteoclastogenesis in bone remodeling and pathological bone loss.
Volume: 22
Issue: 12
Pages: 2046-57
Publication  
First Author: Chung S
Year: 2018
Journal: JCI Insight
Title: TGF-β promotes fibrosis after severe acute kidney injury by enhancing renal macrophage infiltration.
Volume: 3
Issue: 21
Publication
First Author: Chang J
Year: 2015
Journal: Oncotarget
Title: Prostaglandin E receptor 4 (EP4) promotes colonic tumorigenesis.
Volume: 6
Issue: 32
Pages: 33500-11
Publication
First Author: Sugatani T
Year: 2009
Journal: J Biol Chem
Title: Impaired micro-RNA pathways diminish osteoclast differentiation and function.
Volume: 284
Issue: 7
Pages: 4667-78
Genotype
Symbol: Tg(CAG-Bgeo/GFP)21Lbe/? Tg(Itgam-cre)AJva/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Otero JE
Year: 2012
Journal: PLoS One
Title: Constitutively active canonical NF-κB pathway induces severe bone loss in mice.
Volume: 7
Issue: 6
Pages: e38694
Publication
First Author: Morris SM Jr
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Distinct roles of arginases 1 and 2 in diabetic nephropathy.
Volume: 313
Issue: 4
Pages: F899-F905
Publication
First Author: Wang X
Year: 2017
Journal: Diabetes
Title: Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy.
Volume: 66
Issue: 2
Pages: 494-504
Publication
First Author: Zhang MZ
Year: 2015
Journal: J Clin Invest
Title: Inhibition of cyclooxygenase-2 in hematopoietic cells results in salt-sensitive hypertension.
Volume: 125
Issue: 11
Pages: 4281-94
Publication
First Author: Ishii M
Year: 2009
Journal: Nature
Title: Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis.
Volume: 458
Issue: 7237
Pages: 524-8
Publication
First Author: Lotinun S
Year: 2013
Journal: J Clin Invest
Title: Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation.
Volume: 123
Issue: 2
Pages: 666-81
Publication
First Author: Sugatani T
Year: 2011
Journal: Blood
Title: A microRNA expression signature of osteoclastogenesis.
Volume: 117
Issue: 13
Pages: 3648-57
Publication  
First Author: Abram CL
Year: 2014
Journal: J Immunol Methods
Title: Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice.
Volume: 408
Pages: 89-100
Publication
First Author: Huang W
Year: 2016
Journal: PLoS One
Title: Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.
Volume: 11
Issue: 3
Pages: e0152833
Publication
First Author: Dmitrieva-Posocco O
Year: 2019
Journal: Immunity
Title: Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer.
Volume: 50
Issue: 1
Pages: 166-180.e7
Publication
First Author: Martens LH
Year: 2012
Journal: J Clin Invest
Title: Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
Volume: 122
Issue: 11
Pages: 3955-9
Publication
First Author: Kang Z
Year: 2010
Journal: Immunity
Title: Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis.
Volume: 32
Issue: 3
Pages: 414-25
Publication
First Author: Kang Z
Year: 2012
Journal: Immunity
Title: Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population.
Volume: 36
Issue: 5
Pages: 821-33
Publication
First Author: Boillée S
Year: 2006
Journal: Science
Title: Onset and progression in inherited ALS determined by motor neurons and microglia.
Volume: 312
Issue: 5778
Pages: 1389-92
Publication
First Author: Nanou A
Year: 2021
Journal: Cell Rep
Title: Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis.
Volume: 35
Issue: 8
Pages: 109168
Publication
First Author: Liu Q
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: PGE2 signaling via the neuronal EP2 receptor increases injury in a model of cerebral ischemia.
Volume: 116
Issue: 20
Pages: 10019-10024
Publication
First Author: Robblee MM
Year: 2016
Journal: Cell Rep
Title: Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells.
Volume: 14
Issue: 11
Pages: 2611-23
Publication  
First Author: Masuda T
Year: 2016
Journal: Nat Commun
Title: Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain.
Volume: 7
Pages: 12529
Allele
Name: transgene insertion 17, Tsutomu Tanabe
Allele Type: Transgenic
Attribute String: Inducible, Knockdown, Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Saegusa H
Year: 2014
Journal: Biochem Biophys Res Commun
Title: N-type voltage-dependent Ca2+ channel in non-excitable microglial cells in mice is involved in the pathophysiology of neuropathic pain.
Volume: 450
Issue: 1
Pages: 142-7
Publication  
First Author: Huntula S
Year: 2019
Journal: Cell Calcium
Title: Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response.
Volume: 82
Pages: 102059
Publication
First Author: Wang X
Year: 2019
Journal: Sci Rep
Title: Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson's disease model.
Volume: 9
Issue: 1
Pages: 9138
Publication
First Author: Woodling NS
Year: 2014
Journal: J Neurosci
Title: Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.
Volume: 34
Issue: 17
Pages: 5882-94
Publication
First Author: Johansson JU
Year: 2015
Journal: J Clin Invest
Title: Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.
Volume: 125
Issue: 1
Pages: 350-64
Allele
Name: transgene insertion 2781, George Kollias
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: congenic, transgenic
Publication
First Author: Kim D
Year: 2017
Journal: J Immunol
Title: Mesenchymal Cell-Specific MyD88 Signaling Promotes Systemic Dissemination of Salmonella Typhimurium via Inflammatory Monocytes.
Volume: 199
Issue: 4
Pages: 1362-1371
Publication
First Author: Ninou I
Year: 2020
Journal: PLoS One
Title: Genetic deletion of Autotaxin from CD11b+ cells decreases the severity of experimental autoimmune encephalomyelitis.
Volume: 15
Issue: 4
Pages: e0226050
Publication
First Author: Kwan W
Year: 2012
Journal: J Clin Invest
Title: Mutant huntingtin impairs immune cell migration in Huntington disease.
Volume: 122
Issue: 12
Pages: 4737-47
Publication
First Author: Johansson JU
Year: 2013
Journal: J Neurosci
Title: Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia.
Volume: 33
Issue: 40
Pages: 16016-32
Publication
First Author: Yu M
Year: 2014
Journal: J Exp Med
Title: MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases.
Volume: 211
Issue: 5
Pages: 887-907
Publication
First Author: Evangelidou M
Year: 2014
Journal: J Immunol
Title: Altered expression of oligodendrocyte and neuronal marker genes predicts the clinical onset of autoimmune encephalomyelitis and indicates the effectiveness of multiple sclerosis-directed therapeutics.
Volume: 192
Issue: 9
Pages: 4122-33
Publication
First Author: Minhas PS
Year: 2021
Journal: Nature
Title: Restoring metabolism of myeloid cells reverses cognitive decline in ageing.
Volume: 590
Issue: 7844
Pages: 122-128
Publication
First Author: Cheng J
Year: 2020
Journal: Autophagy
Title: Microglial autophagy defect causes parkinson disease-like symptoms by accelerating inflammasome activation in mice.
Volume: 16
Issue: 12
Pages: 2193-2205
Publication
First Author: Ferrini F
Year: 2013
Journal: Nat Neurosci
Title: Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis.
Volume: 16
Issue: 2
Pages: 183-92
Publication
First Author: Shi J
Year: 2010
Journal: J Immunol
Title: The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity.
Volume: 184
Issue: 12
Pages: 7207-18
Publication
First Author: Varvel NH
Year: 2021
Journal: J Neurosci
Title: Peripheral Myeloid Cell EP2 Activation Contributes to the Deleterious Consequences of Status Epilepticus.
Volume: 41
Issue: 5
Pages: 1105-1117
Genotype
Symbol: Tg(ITGAM-cre)2781Gkl/? Tg(SOD1*G37R)1Dwc/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Grn/Grn Tg(ITGAM-cre)2781Gkl/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ptger2/Ptger2 Tg(ITGAM-cre)2781Gkl/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Itgam-cre/ERT2,U6-RNAi:Cacna1b)17Ttan/?
Background: C57BL/6J-Tg(Itgam-cre/ERT2,U6-RNAi:Cacna1b)17Ttan
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(ITGAM-cre)2781Gkl/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Faridi MH
Year: 2017
Journal: J Clin Invest
Title: CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.
Volume: 127
Issue: 4
Pages: 1271-1283
Publication
First Author: Ong LT
Year: 2017
Journal: J Immunol
Title: The Systemic Lupus Erythematosus-Associated Single Nucleotide Polymorphism rs1143678 in Integrin αM Cytoplasmic Tail Generates a 14-3-3ζ Binding Site That Is Proinflammatory.
Volume: 198
Issue: 2
Pages: 883-894
Publication
First Author: Martinez L
Year: 2020
Journal: J Immunol
Title: A Genetic Model of Constitutively Active Integrin CD11b/CD18.
Volume: 205
Issue: 9
Pages: 2545-2553
Publication
First Author: Ueno M
Year: 2013
Journal: Nat Neurosci
Title: Layer V cortical neurons require microglial support for survival during postnatal development.
Volume: 16
Issue: 5
Pages: 543-51
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Pytela R
Year: 1988
Journal: EMBO J
Title: Amino acid sequence of the murine Mac-1 alpha chain reveals homology with the integrin family and an additional domain related to von Willebrand factor.
Volume: 7
Issue: 5
Pages: 1371-8
Publication
First Author: Sastre L
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: A partial genomic DNA clone for the alpha subunit of the mouse complement receptor type 3 and cellular adhesion molecule Mac-1.
Volume: 83
Issue: 15
Pages: 5644-8
Publication
First Author: Hinkle JJ
Year: 2019
Journal: Sci Rep
Title: Cranial irradiation mediated spine loss is sex-specific and complement receptor-3 dependent in male mice.
Volume: 9
Issue: 1
Pages: 18899
Publication
First Author: Czirr E
Year: 2017
Journal: J Exp Med
Title: Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.
Volume: 214
Issue: 4
Pages: 1081-1092
Publication
First Author: Ip CW
Year: 2008
Journal: Mol Cell Neurosci
Title: Origin of CD11b+ macrophage-like cells in the CNS of PLP-overexpressing mice: low influx of haematogenous macrophages and unchanged blood-brain-barrier in the optic nerve.
Volume: 38
Issue: 4
Pages: 489-94
Publication      
First Author: Zhong X
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for invisible
Publication
First Author: Hawley KL
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi.
Volume: 109
Issue: 4
Pages: 1228-32
Publication
First Author: Bullard DC
Year: 2005
Journal: J Immunol
Title: Critical requirement of CD11b (Mac-1) on T cells and accessory cells for development of experimental autoimmune encephalomyelitis.
Volume: 175
Issue: 10
Pages: 6327-33
Publication
First Author: Hu X
Year: 2008
Journal: J Immunol
Title: Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.
Volume: 181
Issue: 10
Pages: 7194-204
Publication
First Author: Hajishengallis G
Year: 2007
Journal: J Immunol
Title: Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivo.
Volume: 179
Issue: 4
Pages: 2359-67
Publication
First Author: Gu C
Year: 2012
Journal: J Immunol
Title: Activation of the classical complement pathway by Bacillus anthracis is the primary mechanism for spore phagocytosis and involves the spore surface protein BclA.
Volume: 188
Issue: 9
Pages: 4421-31
Publication
First Author: Cramer DE
Year: 2006
Journal: Blood
Title: Beta-glucan enhances complement-mediated hematopoietic recovery after bone marrow injury.
Volume: 107
Issue: 2
Pages: 835-40
Publication
First Author: Bai Y
Year: 2012
Journal: J Immunol
Title: Integrin CD11b negatively regulates TLR9-triggered dendritic cell cross-priming by upregulating microRNA-146a.
Volume: 188
Issue: 11
Pages: 5293-302
Publication
First Author: Sisco M
Year: 2007
Journal: Wound Repair Regen
Title: Delayed wound healing in Mac-1-deficient mice is associated with normal monocyte recruitment.
Volume: 15
Issue: 4
Pages: 566-71
Publication
First Author: Rooyakkers AW
Year: 2005
Journal: Microb Pathog
Title: Absence of complement receptor 3 results in reduced binding and ingestion of Mycobacterium tuberculosis but has no significant effect on the induction of reactive oxygen and nitrogen intermediates or on the survival of the bacteria in resident and interferon-gamma activated macrophages.
Volume: 39
Issue: 3
Pages: 57-67