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Search results 1 to 100 out of 489 for Itpr1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Tsuboi D
Year: 2015
Journal: Nat Neurosci
Title: Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity.
Volume: 18
Issue: 5
Pages: 698-707
Publication
First Author: van de Leemput J
Year: 2007
Journal: PLoS Genet
Title: Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans.
Volume: 3
Issue: 6
Pages: e108
Publication  
First Author: Kinoshita A
Year: 2021
Journal: Development
Title: Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells.
Volume: 148
Issue: 16
Publication
First Author: Sun B
Year: 2022
Journal: J Cell Physiol
Title: A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice.
Volume: 237
Issue: 8
Pages: 3305-3316
Publication  
First Author: Yao J
Year: 2023
Journal: Neuroscience
Title: A Gain-of-function Mutation in the Gating Domain of ITPR1 Impairs Motor Movement and Increases Thermal and Mechanical Sensitivity.
Volume: 522
Pages: 11-22
Publication
First Author: McEntagart M
Year: 2016
Journal: Am J Hum Genet
Title: A Restricted Repertoire of De Novo Mutations in ITPR1 Cause Gillespie Syndrome with Evidence for Dominant-Negative Effect.
Volume: 98
Issue: 5
Pages: 981-992
Publication
First Author: Kim J
Year: 2020
Journal: Nucleic Acids Res
Title: Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation.
Volume: 48
Issue: 7
Pages: 3678-3691
GXD Expression    
Probe: MGI:6175691
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190645
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Itpr1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6175691
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190645
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Itpr1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6175691
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190645
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Itpr1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6175691
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190645
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Itpr1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6175691
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190645
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Itpr1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6175691
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190645
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Itpr1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6175691
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190645
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Itpr1
Detected: true
Specimen Num: 6
Protein
Organism: Mus musculus/domesticus
Length: 564  
Fragment?: true
Publication  
First Author: Lane PW
Year: 1972
Journal: Mouse News Lett
Title: Opisthotonus (opt); crooked (Cd).
Volume: 47
Pages: 36-7
Publication
First Author: Przyklenk K
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: First molecular evidence that inositol trisphosphate signaling contributes to infarct size reduction with preconditioning.
Volume: 291
Issue: 4
Pages: H2008-12
Publication
First Author: Aoki T
Year: 2003
Journal: Neurosci Lett
Title: Disruption of the type 1 inositol 1,4,5-trisphosphate receptor gene suppresses the morphine-induced antinociception in the mouse.
Volume: 350
Issue: 2
Pages: 69-72
Publication  
First Author: Street VA
Year: 1996
Journal: Epilepsy Res Suppl
Title: Genomic structure, sequence, and physiological expression of mKv 1.5, a mouse potassium channel gene.
Volume: 12
Pages: 165-75
Publication
First Author: Street VA
Year: 1997
Journal: J Neurosci
Title: The type 1 inositol 1,4,5-trisphosphate receptor gene is altered in the opisthotonos mouse.
Volume: 17
Issue: 2
Pages: 635-45
Publication
First Author: Street VA
Year: 1995
Journal: Genomics
Title: Molecular genetic analysis of distal mouse chromosome 6 defines gene order and positions of the deafwaddler and opisthotonos mutations.
Volume: 29
Issue: 1
Pages: 123-30
Publication
First Author: Zhuang GZ
Year: 2015
Journal: PLoS One
Title: Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.
Volume: 10
Issue: 3
Pages: e0118273
Publication
First Author: Wang H
Year: 2019
Journal: J Gastroenterol
Title: Deletion of IP3R1 by Pdgfrb-Cre in mice results in intestinal pseudo-obstruction and lethality.
Volume: 54
Issue: 5
Pages: 407-418
Publication
First Author: McKee-Johnson JW
Year: 1998
Journal: Genomics
Title: Physical and genetic maps of the deafwaddler region on distal mouse Chr 6.
Volume: 49
Issue: 3
Pages: 371-7
Publication
First Author: Shilling D
Year: 2014
Journal: J Neurosci
Title: Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.
Volume: 34
Issue: 20
Pages: 6910-23
Publication
First Author: Lorenzo DN
Year: 2015
Journal: J Clin Invest
Title: Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic β cell insufficiency.
Volume: 125
Issue: 8
Pages: 3087-102
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Furuichi T
Year: 1989
Journal: Nature
Title: Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400.
Volume: 342
Issue: 6245
Pages: 32-8
Publication
First Author: Furuichi T
Year: 1989
Journal: Nucleic Acids Res
Title: Nucleotide sequence of cDNA encoding P400 protein in the mouse cerebellum.
Volume: 17
Issue: 13
Pages: 5385-6
Publication
First Author: Nakagawa T
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner.
Volume: 88
Issue: 14
Pages: 6244-8
Publication
First Author: Ando H
Year: 2006
Journal: Mol Cell
Title: IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on the IP3 receptor.
Volume: 22
Issue: 6
Pages: 795-806
Publication
First Author: Sugawara T
Year: 2013
Journal: J Neurosci
Title: Type 1 inositol trisphosphate receptor regulates cerebellar circuits by maintaining the spine morphology of purkinje cells in adult mice.
Volume: 33
Issue: 30
Pages: 12186-96
Publication
First Author: Matsumoto M
Year: 1996
Journal: Nature
Title: Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor.
Volume: 379
Issue: 6561
Pages: 168-71
Publication
First Author: Itoh S
Year: 2001
Journal: Brain Res
Title: Neuronal plasticity in hippocampal mossy fiber-CA3 synapses of mice lacking the inositol-1,4,5-trisphosphate type 1 receptor.
Volume: 901
Issue: 1-2
Pages: 237-46
Publication
First Author: Hisatsune C
Year: 2006
Journal: J Neurosci
Title: Inositol 1,4,5-trisphosphate receptor type 1 in granule cells, not in Purkinje cells, regulates the dendritic morphology of Purkinje cells through brain-derived neurotrophic factor production.
Volume: 26
Issue: 42
Pages: 10916-24
Publication
First Author: Ogura H
Year: 2001
Journal: Behav Brain Res
Title: Motor discoordination in mutant mice heterozygous for the type 1 inositol 1,4,5-trisphosphate receptor.
Volume: 122
Issue: 2
Pages: 215-9
Publication
First Author: Bannai H
Year: 2015
Journal: Cell Rep
Title: Bidirectional Control of Synaptic GABAAR Clustering by Glutamate and Calcium.
Volume: 13
Issue: 12
Pages: 2768-80
Publication
First Author: Inoue T
Year: 1998
Journal: J Neurosci
Title: Type 1 inositol 1,4,5-trisphosphate receptor is required for induction of long-term depression in cerebellar Purkinje neurons.
Volume: 18
Issue: 14
Pages: 5366-73
Publication
First Author: Nishiyama M
Year: 2000
Journal: Nature
Title: Calcium stores regulate the polarity and input specificity of synaptic modification.
Volume: 408
Issue: 6812
Pages: 584-8
Publication
First Author: Takano H
Year: 2001
Journal: Auton Neurosci
Title: Mechanical responses evoked by nerve stimulation in gastric muscles of mouse lacking inositol trisphosphate receptor.
Volume: 87
Issue: 2-3
Pages: 249-57
Publication  
First Author: Suzuki H
Year: 2000
Journal: J Physiol
Title: Properties of gastric smooth muscles obtained from mice which lack inositol trisphosphate receptor.
Volume: 525 Pt 1
Pages: 105-11
Publication
First Author: Matsumoto M
Year: 1999
Journal: J Mol Med (Berl)
Title: Type 1 inositol 1,4,5-trisphosphate receptor knock-out mice: their phenotypes and their meaning in neuroscience and clinical practice.
Volume: 77
Issue: 5
Pages: 406-11
Publication
First Author: Fujii S
Year: 2000
Journal: Learn Mem
Title: Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors.
Volume: 7
Issue: 5
Pages: 312-20
Publication
First Author: Yoshioka M
Year: 2010
Journal: Neurosci Res
Title: Intracellular calcium ion dynamics involved in long-term potentiation in hippocampal CA1 neurons in mice lacking the IP3 type 1 receptor.
Volume: 67
Issue: 2
Pages: 149-55
Publication
First Author: Hayashi M
Year: 1999
Journal: J Am Soc Nephrol
Title: Intracellular calcium concentration in the inositol trisphosphate receptor type 1 knockout mouse.
Volume: 10
Issue: 10
Pages: 2094-101
Publication
First Author: Chen B
Year: 2020
Journal: Exp Anim
Title: A C1976Y missense mutation in the mouse Ip3r1 gene leads to short-term mydriasis and unfolded protein response in the iris constrictor muscles.
Volume: 69
Issue: 1
Pages: 45-53
Publication
First Author: Fujimoto T
Year: 2011
Journal: Biochem Biophys Res Commun
Title: KRAS-induced actin-interacting protein regulates inositol 1,4,5-trisphosphate-receptor-mediated calcium release.
Volume: 408
Issue: 2
Pages: 214-7
Publication
First Author: Zhu H
Year: 2011
Journal: J Neurosci
Title: Skeletal muscle IP3R1 receptors amplify physiological and pathological synaptic calcium signals.
Volume: 31
Issue: 43
Pages: 15269-83
Publication
First Author: Kasumu AW
Year: 2012
Journal: J Neurosci
Title: Chronic suppression of inositol 1,4,5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar ataxia 2 mice.
Volume: 32
Issue: 37
Pages: 12786-96
Publication
First Author: Rong YP
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor.
Volume: 106
Issue: 34
Pages: 14397-402
Publication
First Author: Maeda N
Year: 1988
Journal: J Neurochem
Title: Purification and characterization of P400 protein, a glycoprotein characteristic of Purkinje cell, from mouse cerebellum.
Volume: 51
Issue: 6
Pages: 1724-30
Publication  
First Author: Mikoshiba K
Year: 1991
Journal: Adv Exp Med Biol
Title: Primary structure and functional expression of the inositol 1,4,5-trisphosphate receptor, P400.
Volume: 287
Pages: 83-95
Publication  
First Author: Yamada N
Year: 1994
Journal: Biochem J
Title: Human inositol 1,4,5-trisphosphate type-1 receptor, InsP3R1: structure, function, regulation of expression and chromosomal localization.
Volume: 302 ( Pt 3)
Pages: 781-90
Publication  
First Author: Yamada M
Year: 1995
Journal: Biochem J
Title: The calmodulin-binding domain in the mouse type 1 inositol 1,4,5-trisphosphate receptor.
Volume: 308 ( Pt 1)
Pages: 83-8
Publication
First Author: Furutama D
Year: 1996
Journal: J Neurochem
Title: Functional expression of the type 1 inositol 1,4,5-trisphosphate receptor promoter-lacZ fusion genes in transgenic mice.
Volume: 66
Issue: 5
Pages: 1793-801
Publication
First Author: Sienaert I
Year: 1996
Journal: J Biol Chem
Title: Characterization of a cytosolic and a luminal Ca2+ binding site in the type I inositol 1,4,5-trisphosphate receptor.
Volume: 271
Issue: 43
Pages: 27005-12
Publication
First Author: Simonyi A
Year: 1996
Journal: Neuroreport
Title: Chronic ethanol on mRNA levels of IP3R1, IP3 3-kinase and mGluR1 in mouse Purkinje neurons.
Volume: 7
Issue: 13
Pages: 2115-8
Publication
First Author: Konishi Y
Year: 1997
Journal: J Neurochem
Title: Demonstration of an E-box and its CNS-related binding factors for transcriptional regulation of the mouse type 1 inositol 1,4,5-trisphosphate receptor gene.
Volume: 69
Issue: 2
Pages: 476-84
Publication
First Author: Yoshikawa F
Year: 1999
Journal: J Biol Chem
Title: Trypsinized cerebellar inositol 1,4,5-trisphosphate receptor. Structural and functional coupling of cleaved ligand binding and channel domains.
Volume: 274
Issue: 1
Pages: 316-27
Publication
First Author: Yoshikawa F
Year: 1999
Journal: J Biol Chem
Title: Cooperative formation of the ligand-binding site of the inositol 1,4, 5-trisphosphate receptor by two separable domains.
Volume: 274
Issue: 1
Pages: 328-34
Publication
First Author: Ohkawa N
Year: 1999
Journal: Gene
Title: Activation of the mouse inositol 1,4,5-trisphosphate receptor type 1 promoter by AP-2.
Volume: 229
Issue: 1-2
Pages: 11-9
Publication
First Author: Michikawa T
Year: 1999
Journal: Neuron
Title: Calmodulin mediates calcium-dependent inactivation of the cerebellar type 1 inositol 1,4,5-trisphosphate receptor.
Volume: 23
Issue: 4
Pages: 799-808
Publication
First Author: Powell JA
Year: 2003
Journal: J Neurosci
Title: IP3 receptors and associated Ca2+ signals localize to satellite cells and to components of the neuromuscular junction in skeletal muscle.
Volume: 23
Issue: 23
Pages: 8185-92
Publication
First Author: Bosanac I
Year: 2004
Journal: Biochim Biophys Acta
Title: Structural insights into the regulatory mechanism of IP3 receptor.
Volume: 1742
Issue: 1-3
Pages: 89-102
Publication
First Author: Bai GR
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Inositol 1,4,5-trisphosphate receptor type 1 phosphorylation and regulation by extracellular signal-regulated kinase.
Volume: 348
Issue: 4
Pages: 1319-27
Publication
First Author: Harnick DJ
Year: 1995
Journal: J Biol Chem
Title: The human type 1 inositol 1,4,5-trisphosphate receptor from T lymphocytes. Structure, localization, and tyrosine phosphorylation.
Volume: 270
Issue: 6
Pages: 2833-40
Publication
First Author: Betzenhauser MJ
Year: 2008
Journal: J Biol Chem
Title: ATP modulation of Ca2+ release by type-2 and type-3 inositol (1, 4, 5)-triphosphate receptors. Differing ATP sensitivities and molecular determinants of action.
Volume: 283
Issue: 31
Pages: 21579-87
Publication
First Author: Isakson BE
Year: 2008
Journal: J Cell Sci
Title: Localized expression of an Ins(1,4,5)P3 receptor at the myoendothelial junction selectively regulates heterocellular Ca2+ communication.
Volume: 121
Issue: Pt 21
Pages: 3664-73
Publication
First Author: Hours MC
Year: 2010
Journal: J Cell Sci
Title: The N-terminal domain of the type 1 Ins(1,4,5)P3 receptor stably expressed in MDCK cells interacts with myosin IIA and alters epithelial cell morphology.
Volume: 123
Issue: Pt 9
Pages: 1449-59
Publication
First Author: Chan J
Year: 2007
Journal: J Mol Biol
Title: Ligand-induced conformational changes via flexible linkers in the amino-terminal region of the inositol 1,4,5-trisphosphate receptor.
Volume: 373
Issue: 5
Pages: 1269-80
Publication
First Author: Bauer PO
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Genetic ablation and chemical inhibition of IP3R1 reduce mutant huntingtin aggregation.
Volume: 416
Issue: 1-2
Pages: 13-7
Publication
First Author: Yuan Q
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS.
Volume: 113
Issue: 30
Pages: 8532-7