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Search results 1 to 100 out of 241 for Itpr2

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
3709 | ITPR2
Type: gene
Organism: human
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Gene
100124748 | itpr2
Type: gene
Organism: frog, western clawed
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Gene
81678 | Itpr2
Type: gene
Organism: rat
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Gene
473389 | ITPR2
Type: gene
Organism: chimpanzee
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Gene
486628 | ITPR2
Type: gene
Organism: dog, domestic
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Gene
281878 | ITPR2
Type: gene
Organism: cattle
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Gene
418212 | ITPR2
Type: gene
Organism: chicken
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Gene
562585 | itpr2
Type: gene
Organism: zebrafish
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Gene
708714 | ITPR2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:99418 | Itpr2
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
139355255 | ITPR2-AS2
Type: gene
Organism: human
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Publication
33526781 | J:302418
First Author: Ziegler DV
Year: 2021
Journal: Nat Commun
Title: Calcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and aging.
Volume: 12
Issue: 1
Pages: 720
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GXD Expression
GXD Expression
   
Probe: MGI:4425486
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4825666
Age: embryonic day 14.5
Specimen Label: Table S5 - Itpr2
Detected: true
Specimen Num: 1
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Publication
38476116 | J:347111
   
First Author: Zhang M
Year: 2024
Journal: Adv Sci (Weinh)
Title: ITPR2 Mediated Calcium Homeostasis in Oligodendrocytes is Essential for Myelination and Involved in Depressive-Like Behavior in Adolescent Mice.
Pages: e2306498
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Protein
Q497U9
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: true
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Publication
27378687 | J:237868
First Author: Staats KA
Year: 2016
Journal: Hum Mol Genet
Title: Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice.
Volume: 25
Issue: 16
Pages: 3491-3499
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Publication
32952549 | J:327538
 
First Author: Zeng S
Year: 2020
Journal: Neural Plast
Title: In Vivo Structural and Functional Abnormalities of the Striatums Is Related to Decreased Astrocytic BDNF in Itpr2-/- Mice Exhibiting Depressive-Like Behavior.
Volume: 2020
Pages: 8830670
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Publication
34630045 | J:312490
 
First Author: Mei R
Year: 2021
Journal: Front Cell Neurosci
Title: Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers.
Volume: 15
Pages: 751439
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Protein Coding Gene
MGP_CAROLIEiJ_G0029053 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031485 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031460 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031388 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031468 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031189 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_99418 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030557 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031305 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031257 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031390 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031297 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031962 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030284 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030650 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022815 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030108 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
20189985 | J:164619
First Author: Tovey SC
Year: 2010
Journal: J Biol Chem
Title: Regulation of inositol 1,4,5-trisphosphate receptors by cAMP independent of cAMP-dependent protein kinase.
Volume: 285
Issue: 17
Pages: 12979-89
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Publication
19608738 | J:154879
First Author: Betzenhauser MJ
Year: 2009
Journal: J Biol Chem
Title: Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937.
Volume: 284
Issue: 37
Pages: 25116-25
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Publication
25329695 | J:217699
First Author: Klar J
Year: 2014
Journal: J Clin Invest
Title: Abolished InsP3R2 function inhibits sweat secretion in both humans and mice.
Volume: 124
Issue: 11
Pages: 4773-80
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Publication
15933266 | J:110271
First Author: Li X
Year: 2005
Journal: Circ Res
Title: Endothelin-1-induced arrhythmogenic Ca2+ signaling is abolished in atrial myocytes of inositol-1,4,5-trisphosphate(IP3)-receptor type 2-deficient mice.
Volume: 96
Issue: 12
Pages: 1274-81
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Publication
28132831 | J:254093
First Author: Agarwal A
Year: 2017
Journal: Neuron
Title: Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes.
Volume: 93
Issue: 3
Pages: 587-605.e7
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Publication
31444225 | J:288495
 
First Author: Mishima T
Year: 2019
Journal: eNeuro
Title: Transcranial Direct Current Stimulation (tDCS) Induces Adrenergic Receptor-Dependent Microglial Morphological Changes in Mice.
Volume: 6
Issue: 5
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Publication
27064281 | J:234941
First Author: Kim SK
Year: 2016
Journal: J Clin Invest
Title: Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain.
Volume: 126
Issue: 5
Pages: 1983-97
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Publication
27000523 | J:236747
 
First Author: Monai H
Year: 2016
Journal: Nat Commun
Title: Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain.
Volume: 7
Pages: 11100
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Publication
22159127 | J:317113
First Author: Takata N
Year: 2011
Journal: J Neurosci
Title: Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo.
Volume: 31
Issue: 49
Pages: 18155-65
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Publication
23258573 | J:252072
First Author: Cooley N
Year: 2013
Journal: Circ Heart Fail
Title: No contribution of IP3-R(2) to disease phenotype in models of dilated cardiomyopathy or pressure overload hypertrophy.
Volume: 6
Issue: 2
Pages: 318-25
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Publication
23112168 | J:191737
First Author: Thrane AS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex.
Volume: 109
Issue: 46
Pages: 18974-9
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Publication
37445783 | J:354239
 
First Author: Cunha-Garcia D
Year: 2023
Journal: Int J Mol Sci
Title: Genetic Ablation of Inositol 1,4,5-Trisphosphate Receptor Type 2 (IP(3)R2) Fails to Modify Disease Progression in a Mouse Model of Spinocerebellar Ataxia Type 3.
Volume: 24
Issue: 13
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Publication
24742463 | J:209943
First Author: Haustein MD
Year: 2014
Journal: Neuron
Title: Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway.
Volume: 82
Issue: 2
Pages: 413-29
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Publication
34139149 | J:325336
First Author: Nagai J
Year: 2021
Journal: Neuron
Title: Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK.
Volume: 109
Issue: 14
Pages: 2256-2274.e9
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Publication
26433454 | J:313141
First Author: Li H
Year: 2015
Journal: Cell Calcium
Title: Disruption of IP₃R2-mediated Ca²⁺ signaling pathway in astrocytes ameliorates neuronal death and brain damage while reducing behavioral deficits after focal ischemic stroke.
Volume: 58
Issue: 6
Pages: 565-76
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Publication
32609904 | J:331516
First Author: Guillot de Suduiraut I
Year: 2021
Journal: Eur J Neurosci
Title: Astrocytic release of ATP through type 2 inositol 1,4,5-trisphosphate receptor calcium signaling and social dominance behavior in mice.
Volume: 53
Issue: 9
Pages: 2973-2985
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Publication
30455631 | J:276239
 
First Author: Guerra-Gomes S
Year: 2018
Journal: Front Cell Neurosci
Title: The Role of Astrocytic Calcium Signaling in the Aged Prefrontal Cortex.
Volume: 12
Pages: 379
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Publication
28981616 | J:279492
First Author: Wu DC
Year: 2018
Journal: Cereb Cortex
Title: Spreading Depression Promotes Astrocytic Calcium Oscillations and Enhances Gliotransmission to Hippocampal Neurons.
Volume: 28
Issue: 9
Pages: 3204-3216
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Publication
30169757 | J:281686
First Author: Heuser K
Year: 2018
Journal: Cereb Cortex
Title: Ca2+ Signals in Astrocytes Facilitate Spread of Epileptiform Activity.
Volume: 28
Issue: 11
Pages: 4036-4048
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Publication
18463250 | J:149336
First Author: Petravicz J
Year: 2008
Journal: J Neurosci
Title: Loss of IP3 receptor-dependent Ca2+ increases in hippocampal astrocytes does not affect baseline CA1 pyramidal neuron synaptic activity.
Volume: 28
Issue: 19
Pages: 4967-73
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Publication
29488635 | J:284710
First Author: Xiong Y
Year: 2018
Journal: J Physiol
Title: Stretch-induced Ca2+ independent ATP release in hippocampal astrocytes.
Volume: 596
Issue: 10
Pages: 1931-1947
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Publication
23185258 | J:195582
First Author: Orabi AI
Year: 2012
Journal: PLoS One
Title: IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules.
Volume: 7
Issue: 11
Pages: e48465
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Publication
32632168 | J:292329
First Author: Bojarskaite L
Year: 2020
Journal: Nat Commun
Title: Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep.
Volume: 11
Issue: 1
Pages: 3240
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Publication
22347811 | J:184568
First Author: Navarrete M
Year: 2012
Journal: PLoS Biol
Title: Astrocytes mediate in vivo cholinergic-induced synaptic plasticity.
Volume: 10
Issue: 2
Pages: e1001259
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Publication
30801845 | J:274727
First Author: Durkee CA
Year: 2019
Journal: Glia
Title: Gi/o protein-coupled receptors inhibit neurons but activate astrocytes and stimulate gliotransmission.
Volume: 67
Issue: 6
Pages: 1076-1093
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Publication
31348567 | J:279729
First Author: Pinto-Duarte A
Year: 2019
Journal: Glia
Title: Impairments in remote memory caused by the lack of Type 2 IP3 receptors.
Volume: 67
Issue: 10
Pages: 1976-1989
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Publication
27605617 | J:235204
First Author: Biesecker KR
Year: 2016
Journal: J Neurosci
Title: Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina.
Volume: 36
Issue: 36
Pages: 9435-45
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Publication
33830504 | J:317470
First Author: Rosa JM
Year: 2021
Journal: Br J Pharmacol
Title: TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury.
Volume: 178
Issue: 17
Pages: 3395-3413
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Publication
30306640 | J:269379
First Author: Okubo Y
Year: 2019
Journal: Glia
Title: Inositol 1,4,5-trisphosphate receptor type 2-independent Ca2+ release from the endoplasmic reticulum in astrocytes.
Volume: 67
Issue: 1
Pages: 113-124
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Publication
24042499 | J:215844
First Author: Agulhon C
Year: 2013
Journal: J Physiol
Title: Modulation of the autonomic nervous system and behaviour by acute glial cell Gq protein-coupled receptor activation in vivo.
Volume: 591
Issue: 22
Pages: 5599-609
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Publication
37773446 | J:349107
First Author: González-Arias C
Year: 2023
Journal: Mol Psychiatry
Title: Dysfunctional serotonergic neuron-astrocyte signaling in depressive-like states.
Volume: 28
Issue: 9
Pages: 3856-3873
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Publication
34767261 | J:327728
First Author: Del Franco AP
Year: 2022
Journal: Glia
Title: Dilation of cortical capillaries is not related to astrocyte calcium signaling.
Volume: 70
Issue: 3
Pages: 508-521
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Publication
28742117 | J:248043
First Author: Ye L
Year: 2017
Journal: PLoS One
Title: Comparison of GCaMP3 and GCaMP6f for studying astrocyte Ca2+ dynamics in the awake mouse brain.
Volume: 12
Issue: 7
Pages: e0181113
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Publication
25232111 | J:216500
First Author: Perez-Alvarez A
Year: 2014
Journal: J Neurosci
Title: Structural and functional plasticity of astrocyte processes and dendritic spine interactions.
Volume: 34
Issue: 38
Pages: 12738-44
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Publication
25253859 | J:277967
First Author: Bonder DE
Year: 2014
Journal: J Neurosci
Title: Astrocytic Gq-GPCR-linked IP3R-dependent Ca2+ signaling does not mediate neurovascular coupling in mouse visual cortex in vivo.
Volume: 34
Issue: 39
Pages: 13139-50
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Publication
32541069 | J:295360
First Author: Cavaccini A
Year: 2020
Journal: J Neurosci
Title: Astrocyte Signaling Gates Long-Term Depression at Corticostriatal Synapses of the Direct Pathway.
Volume: 40
Issue: 30
Pages: 5757-5768
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Publication
23658179 | J:198433
First Author: Nizar K
Year: 2013
Journal: J Neurosci
Title: In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase.
Volume: 33
Issue: 19
Pages: 8411-22
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Publication
18658132 | J:141983
First Author: Park HS
Year: 2008
Journal: J Biol Chem
Title: The type 2 inositol (1,4,5)-trisphosphate (InsP3) receptor determines the sensitivity of InsP3-induced Ca2+ release to ATP in pancreatic acinar cells.
Volume: 283
Issue: 38
Pages: 26081-8
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Publication
25894291 | J:222858
First Author: Srinivasan R
Year: 2015
Journal: Nat Neurosci
Title: Ca(2+) signaling in astrocytes from Ip3r2(-/-) mice in brain slices and during startle responses in vivo.
Volume: 18
Issue: 5
Pages: 708-17
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Publication
25315698 | J:218406
First Author: Feriod CN
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Inositol 1,4,5-trisphosphate receptor type II (InsP3R-II) is reduced in obese mice, but metabolic homeostasis is preserved in mice lacking InsP3R-II.
Volume: 307
Issue: 11
Pages: E1057-64
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Publication
36383661 | J:331964
First Author: Liu J
Year: 2022
Journal: Sci Adv
Title: Astrocyte dysfunction drives abnormal resting-state functional connectivity in depression.
Volume: 8
Issue: 46
Pages: eabo2098
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Publication
19429168 | J:150441
First Author: Lipp S
Year: 2009
Journal: Neurosci Lett
Title: Calcium responses mediated by type 2 IP3-receptors are required for osmotic volume regulation of retinal glial cells in mice.
Volume: 457
Issue: 2
Pages: 85-8
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Publication
21960523 | J:183337
First Author: Park HS
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Regulation of Ca²⁺ release through inositol 1,4,5-trisphosphate receptors by adenine nucleotides in parotid acinar cells.
Volume: 302
Issue: 1
Pages: G97-G104
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Publication
26274565 | J:226718
   
First Author: Rosa JM
Year: 2015
Journal: Elife
Title: Neuron-glia signaling in developing retina mediated by neurotransmitter spillover.
Volume: 4
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Publication
21852551 | J:188828
First Author: Ju YK
Year: 2011
Journal: Circ Res
Title: Distribution and functional role of inositol 1,4,5-trisphosphate receptors in mouse sinoatrial node.
Volume: 109
Issue: 8
Pages: 848-57
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Publication
25429263 | J:242261
 
First Author: Petravicz J
Year: 2014
Journal: Front Behav Neurosci
Title: Astrocyte IP3R2-dependent Ca(2+) signaling is not a major modulator of neuronal pathways governing behavior.
Volume: 8
Pages: 384
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Publication
22547829 | J:184791
First Author: Wang F
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Bergmann glia modulate cerebellar Purkinje cell bistability via Ca2+-dependent K+ uptake.
Volume: 109
Issue: 20
Pages: 7911-6
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Publication
37543946 | J:339948
First Author: Miguel-Quesada C
Year: 2023
Journal: Cell Rep
Title: Astrocytes adjust the dynamic range of cortical network activity to control modality-specific sensory information processing.
Volume: 42
Issue: 8
Pages: 112950
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Publication
29706581 | J:267943
First Author: Stobart JL
Year: 2018
Journal: Neuron
Title: Cortical Circuit Activity Evokes Rapid Astrocyte Calcium Signals on a Similar Timescale to Neurons.
Volume: 98
Issue: 4
Pages: 726-735.e4
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Publication
23012414 | J:190328
First Author: Chen N
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Nucleus basalis-enabled stimulus-specific plasticity in the visual cortex is mediated by astrocytes.
Volume: 109
Issue: 41
Pages: E2832-41
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Publication
20616315 | J:169368
First Author: Nakayama H
Year: 2010
Journal: Circ Res
Title: The IP3 receptor regulates cardiac hypertrophy in response to select stimuli.
Volume: 107
Issue: 5
Pages: 659-66
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Publication
11722588 | J:72774
First Author: Magnino F
Year: 2001
Journal: Eur J Biochem
Title: Rat inositol 1,4,5-trisphosphate receptor isoform 2 interacts with itself in its C-terminal portion and upstream of the first transmembrane domain.
Volume: 268
Issue: 22
Pages: 5981-8
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Publication
11694504 | J:73697
First Author: Bruce JI
Year: 2002
Journal: J Biol Chem
Title: Phosphorylation of inositol 1,4,5-trisphosphate receptors in parotid acinar cells. A mechanism for the synergistic effects of cAMP on Ca2+ signaling.
Volume: 277
Issue: 2
Pages: 1340-8
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Publication
23166348 | J:195248
First Author: Drawnel FM
Year: 2012
Journal: J Cell Biol
Title: Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy.
Volume: 199
Issue: 5
Pages: 783-98
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Publication
23702310 | J:201548
 
First Author: Dong QP
Year: 2013
Journal: Neurobiol Dis
Title: Astrocytic Ca(2+) waves mediate activation of extrasynaptic NMDA receptors in hippocampal neurons to aggravate brain damage during ischemia.
Volume: 58
Pages: 68-75
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Publication
25499268 | J:251606
First Author: Vervloessem T
Year: 2015
Journal: Biochim Biophys Acta
Title: The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca²⁺-release channel.
Volume: 1853
Issue: 9
Pages: 1992-2005
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GXD Expression
GXD Expression
     
Probe: MGI:6431020
Assay Type: RT-PCR
Annotation Date: 2020-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6431056
Age: postnatal adult
Specimen Label: Sp
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6431020
Assay Type: RT-PCR
Annotation Date: 2020-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6431056
Age: postnatal adult
Specimen Label: Li
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6431020
Assay Type: RT-PCR
Annotation Date: 2020-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6431056
Age: postnatal adult
Specimen Label: SM
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6431020
Assay Type: RT-PCR
Annotation Date: 2020-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6431056
Age: postnatal adult
Specimen Label: H
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6431020
Assay Type: RT-PCR
Annotation Date: 2020-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6431056
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6431020
Assay Type: RT-PCR
Annotation Date: 2020-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6431056
Age: postnatal adult
Specimen Label: Ad
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6431020
Assay Type: RT-PCR
Annotation Date: 2020-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6431056
Age: embryonic day 11.5
Specimen Label: E11
Detected: true
Specimen Num: 5
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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