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Search results 1 to 100 out of 368 for Izumo1

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0.031s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Izumo sperm-egg fusion protein 1 (IZUMO1) is an essential sperm cell-surface protein required for fertilisation by acting as a ligandfor IZUMO1R/JUNO receptor on eggs []. It is a member of an immunoglobulin superfamily and possesses a well-conserved putative N-glycosylation site. However, glycosylation is not essential for the function of IZUMO, but has a role in protecting it from fragmentation in cauda epididymis [].
Publication
First Author: Inoue N
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Putative sperm fusion protein IZUMO and the role of N-glycosylation.
Volume: 377
Issue: 3
Pages: 910-4
Publication
First Author: Inoue N
Year: 2005
Journal: Nature
Title: The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs.
Volume: 434
Issue: 7030
Pages: 234-8
Publication  
First Author: Kato K
Year: 2016
Journal: Nat Commun
Title: Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.
Volume: 7
Pages: 12198
Gene
Type: gene
Organism: Homo sapiens
Publication  
First Author: Inoue N
Year: 2015
Journal: Nat Commun
Title: Oocyte-triggered dimerization of sperm IZUMO1 promotes sperm-egg fusion in mice.
Volume: 6
Pages: 8858
Publication
First Author: Saito T
Year: 2019
Journal: Sci Rep
Title: Alternative splicing of the Izumo1 gene ensures triggering gamete fusion in mice.
Volume: 9
Issue: 1
Pages: 3151
Publication
First Author: Young SA
Year: 2016
Journal: Reproduction
Title: CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility.
Volume: 152
Issue: 6
Pages: 665-672
Publication
First Author: Inoue N
Year: 2018
Journal: Cell Cycle
Title: Monitoring dimeric status of IZUMO1 during the acrosome reaction in living spermatozoon.
Volume: 17
Issue: 11
Pages: 1279-1285
Publication
First Author: Bianchi E
Year: 2014
Journal: Nature
Title: Juno is the egg Izumo receptor and is essential for mammalian fertilization.
Volume: 508
Issue: 7497
Pages: 483-7
Publication  
First Author: Inoue N
Year: 2020
Journal: Development
Title: Unveiling a novel function of CD9 in surface compartmentalization of oocytes.
Volume: 147
Issue: 15
Publication
First Author: Nishimura H
Year: 2011
Journal: Reproduction
Title: Characterization of mouse sperm TMEM190, a small transmembrane protein with the trefoil domain: evidence for co-localization with IZUMO1 and complex formation with other sperm proteins.
Volume: 141
Issue: 4
Pages: 437-51
Protein
Organism: Mus musculus
Length: 397  
Fragment?: false
Protein
Organism: Mus musculus
Length: 428  
Fragment?: false
Publication
First Author: Satouh Y
Year: 2012
Journal: J Cell Sci
Title: Visualization of the moment of mouse sperm-egg fusion and dynamic localization of IZUMO1.
Volume: 125
Issue: Pt 21
Pages: 4985-90
Publication  
First Author: Saito T
Year: 2019
Journal: Int J Mol Sci
Title: Sperm IZUMO1-Dependent Gamete Fusion Influences Male Fertility in Mice.
Volume: 20
Issue: 19
Publication
First Author: Ohto U
Year: 2016
Journal: Nature
Title: Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization.
Volume: 534
Issue: 7608
Pages: 566-9
Gene
Type: gene
Organism: Rattus norvegicus
Publication
First Author: Gaikwad AS
Year: 2019
Journal: BMC Biol
Title: GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse.
Volume: 17
Issue: 1
Pages: 86
Publication    
First Author: Inoue N
Year: 2021
Journal: Elife
Title: Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion.
Volume: 10
Publication
First Author: Inoue N
Year: 2010
Journal: PLoS One
Title: Identification and disruption of sperm-specific angiotensin converting enzyme-3 (ACE3) in mouse.
Volume: 5
Issue: 4
Pages: e10301
Publication
First Author: Inoue N
Year: 2013
Journal: Development
Title: Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion.
Volume: 140
Issue: 15
Pages: 3221-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Umemura M
Year: 2017
Journal: Front Behav Neurosci
Title: Comprehensive Behavioral Analysis of Activating Transcription Factor 5-Deficient Mice.
Volume: 11
Pages: 125
Publication
First Author: Ellerman DA
Year: 2009
Journal: Mol Reprod Dev
Title: Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm.
Volume: 76
Issue: 12
Pages: 1188-99
Publication
First Author: Fujihara Y
Year: 2010
Journal: J Cell Sci
Title: Sperm equatorial segment protein 1, SPESP1, is required for fully fertile sperm in mouse.
Volume: 123
Issue: Pt 9
Pages: 1531-6
Publication
First Author: Inoue N
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs.
Volume: 108
Issue: 50
Pages: 20008-11
Publication
First Author: Larasati T
Year: 2020
Journal: Biol Reprod
Title: Tmprss12 is required for sperm motility and uterotubal junction migration in miceā€ .
Volume: 103
Issue: 2
Pages: 254-263
Publication
First Author: Umemura M
Year: 2015
Journal: Biosci Biotechnol Biochem
Title: Activating transcription factor 5 is required for mouse olfactory bulb development via interneuron.
Volume: 79
Issue: 7
Pages: 1082-9
Publication
First Author: Miranda PV
Year: 2009
Journal: Biol Reprod
Title: Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm.
Volume: 80
Issue: 5
Pages: 897-904
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Vicens A
Year: 2014
Journal: Biol Reprod
Title: Coevolution of positively selected IZUMO1 and CD9 in rodents: evidence of interaction between gamete fusion proteins?
Volume: 90
Issue: 5
Pages: 113
Publication
First Author: Salbaum JM
Year: 2013
Journal: Biochim Biophys Acta
Title: Mutation at the folate receptor 4 locus modulates gene expression profiles in the mouse uterus in response to periconceptional folate supplementation.
Volume: 1832
Issue: 10
Pages: 1653-61
Allele      
Name: IZUMO1 receptor, JUNO; wild type
ProxyCollection
Allele
Name: IZUMO1 receptor, JUNO; targeted mutation 1, J Michael Salbaum
Allele Type: Targeted
Attribute String: Conditional ready
Publication categories: ProxyCollection
Allele
Name: IZUMO1 receptor, JUNO; targeted mutation 1.1, J Michael Salbaum
Allele Type: Targeted
Attribute String: Null/knockout
Publication categories: ProxyCollection
Allele
Name: IZUMO1 receptor, JUNO; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication categories: ProxyCollection
Allele
Name: IZUMO1 receptor, JUNO; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication categories: ProxyCollection
Allele
Name: IZUMO1 receptor, JUNO; targeted mutation 2c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready
Publication categories: ProxyCollection
Allele
Name: IZUMO1 receptor, JUNO; targeted mutation 2a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Publication categories: ProxyCollection
Allele
Name: IZUMO1 receptor, JUNO; targeted mutation 2e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication categories: ProxyCollection
Allele
Name: IZUMO1 receptor, JUNO; endonuclease-mediated mutation 1, Naokazu Inoue
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s), Null/knockout
Publication categories: ProxyCollection
Allele
Name: IZUMO1 receptor, JUNO; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Publication categories: ProxyCollection
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus