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Search results 1 to 100 out of 388 for Izumo1

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Type Details Score
Gene
284359 | IZUMO1
Type: gene
Organism: human
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Gene
612013 | IZUMO1
Type: gene
Organism: dog, domestic
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Gene
618057 | IZUMO1
Type: gene
Organism: cattle
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Gene
100329365 | izumo1
Type: gene
Organism: zebrafish
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Gene
718234 | IZUMO1
Type: gene
Organism: macaque, rhesus
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Gene
107969781 | IZUMO1
Type: gene
Organism: chimpanzee
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Gene
499152 | Izumo1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1920706 | Izumo1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR032700 | IZUMO1
Type: Family
Description: Izumo sperm-egg fusion protein 1 (IZUMO1) is an essential sperm cell-surface protein required for fertilisation by acting as a ligand for IZUMO1R/JUNO receptor on eggs []. It is a member of an immunoglobulin superfamily and possesses a well-conserved putative N-glycosylation site. However, glycosylation is not essential for the function of IZUMO, but has a role in protecting it from fragmentation in cauda epididymis [].
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Publication
18952059 | J:144869
First Author: Inoue N
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Putative sperm fusion protein IZUMO and the role of N-glycosylation.
Volume: 377
Issue: 3
Pages: 910-4
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Publication
15759005 | J:97563
First Author: Inoue N
Year: 2005
Journal: Nature
Title: The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs.
Volume: 434
Issue: 7030
Pages: 234-8
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Publication
27416963 | J:240828
 
First Author: Kato K
Year: 2016
Journal: Nat Commun
Title: Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.
Volume: 7
Pages: 12198
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Publication
26568141 | J:228028
 
First Author: Inoue N
Year: 2015
Journal: Nat Commun
Title: Oocyte-triggered dimerization of sperm IZUMO1 promotes sperm-egg fusion in mice.
Volume: 6
Pages: 8858
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Gene
390243 | IZUMO1R
Type: gene
Organism: human
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Publication
30816314 | J:275429
First Author: Saito T
Year: 2019
Journal: Sci Rep
Title: Alternative splicing of the Izumo1 gene ensures triggering gamete fusion in mice.
Volume: 9
Issue: 1
Pages: 3151
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Publication
36394541 | J:333062
 
First Author: Brukman NG
Year: 2023
Journal: J Cell Biol
Title: A novel function for the sperm adhesion protein IZUMO1 in cell-cell fusion.
Volume: 222
Issue: 2
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Publication
29954238 | J:278260
First Author: Inoue N
Year: 2018
Journal: Cell Cycle
Title: Monitoring dimeric status of IZUMO1 during the acrosome reaction in living spermatozoon.
Volume: 17
Issue: 11
Pages: 1279-1285
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Publication
27624483 | J:258196
First Author: Young SA
Year: 2016
Journal: Reproduction
Title: CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility.
Volume: 152
Issue: 6
Pages: 665-672
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Publication
35960805 | J:328498
First Author: Contreras W
Year: 2022
Journal: Sci Adv
Title: C11orf94/Frey is a key regulator for male fertility by controlling Izumo1 complex assembly.
Volume: 8
Issue: 32
Pages: eabo6049
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Publication
35096839 | J:337404
 
First Author: Matsumura T
Year: 2021
Journal: Front Cell Dev Biol
Title: Sperm IZUMO1 Is Required for Binding Preceding Fusion With Oolemma in Mice and Rats.
Volume: 9
Pages: 810118
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Publication
24739963 | J:209568
First Author: Bianchi E
Year: 2014
Journal: Nature
Title: Juno is the egg Izumo receptor and is essential for mammalian fertilization.
Volume: 508
Issue: 7497
Pages: 483-7
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Publication
32665248 | J:297089
 
First Author: Inoue N
Year: 2020
Journal: Development
Title: Unveiling a novel function of CD9 in surface compartmentalization of oocytes.
Volume: 147
Issue: 15
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Publication
21273369 | J:180946
First Author: Nishimura H
Year: 2011
Journal: Reproduction
Title: Characterization of mouse sperm TMEM190, a small transmembrane protein with the trefoil domain: evidence for co-localization with IZUMO1 and complex formation with other sperm proteins.
Volume: 141
Issue: 4
Pages: 437-51
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Protein
Q9D9J7
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: false
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Protein
A0A455R725
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
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Publication
22946049 | J:200283
First Author: Satouh Y
Year: 2012
Journal: J Cell Sci
Title: Visualization of the moment of mouse sperm-egg fusion and dynamic localization of IZUMO1.
Volume: 125
Issue: Pt 21
Pages: 4985-90
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Publication
31569716 | J:307564
 
First Author: Saito T
Year: 2019
Journal: Int J Mol Sci
Title: Sperm IZUMO1-Dependent Gamete Fusion Influences Male Fertility in Mice.
Volume: 20
Issue: 19
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Publication
27309808 | J:235303
First Author: Ohto U
Year: 2016
Journal: Nature
Title: Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization.
Volume: 534
Issue: 7608
Pages: 566-9
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Publication
33871360 | J:304712
   
First Author: Inoue N
Year: 2021
Journal: Elife
Title: Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion.
Volume: 10
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Publication
31672133 | J:290694
First Author: Gaikwad AS
Year: 2019
Journal: BMC Biol
Title: GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse.
Volume: 17
Issue: 1
Pages: 86
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Publication
23824580 | J:198624
First Author: Inoue N
Year: 2013
Journal: Development
Title: Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion.
Volume: 140
Issue: 15
Pages: 3221-9
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Publication
20421979 | J:160139
First Author: Inoue N
Year: 2010
Journal: PLoS One
Title: Identification and disruption of sperm-specific angiotensin converting enzyme-3 (ACE3) in mouse.
Volume: 5
Issue: 4
Pages: e10301
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Protein Coding Gene
MGP_CAROLIEiJ_G0029731 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032213 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032225 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031940 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1920706 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031269 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031905 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032063 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032014 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032141 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030991 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031386 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012956 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030829 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
28744205 | J:274991
 
First Author: Umemura M
Year: 2017
Journal: Front Behav Neurosci
Title: Comprehensive Behavioral Analysis of Activating Transcription Factor 5-Deficient Mice.
Volume: 11
Pages: 125
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Publication
19658160 | J:155060
First Author: Ellerman DA
Year: 2009
Journal: Mol Reprod Dev
Title: Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm.
Volume: 76
Issue: 12
Pages: 1188-99
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Publication
20375058 | J:159611
First Author: Fujihara Y
Year: 2010
Journal: J Cell Sci
Title: Sperm equatorial segment protein 1, SPESP1, is required for fully fertile sperm in mouse.
Volume: 123
Issue: Pt 9
Pages: 1531-6
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Publication
22084105 | J:180392
First Author: Inoue N
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs.
Volume: 108
Issue: 50
Pages: 20008-11
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Publication
32529245 | J:293874
First Author: Larasati T
Year: 2020
Journal: Biol Reprod
Title: Tmprss12 is required for sperm motility and uterotubal junction migration in mice†.
Volume: 103
Issue: 2
Pages: 254-263
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Publication
25704077 | J:260656
First Author: Umemura M
Year: 2015
Journal: Biosci Biotechnol Biochem
Title: Activating transcription factor 5 is required for mouse olfactory bulb development via interneuron.
Volume: 79
Issue: 7
Pages: 1082-9
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Publication
19144954 | J:149637
First Author: Miranda PV
Year: 2009
Journal: Biol Reprod
Title: Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm.
Volume: 80
Issue: 5
Pages: 897-904
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Gene
690037 | Izumo1r
Type: gene
Organism: rat
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Gene
737722 | IZUMO1R
Type: gene
Organism: chimpanzee
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Gene
607523 | IZUMO1R
Type: gene
Organism: dog, domestic
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Gene
100300332 | IZUMO1R
Type: gene
Organism: cattle
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Gene
698653 | IZUMO1R
Type: gene
Organism: macaque, rhesus
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Gene
100135193 | izumo1r
Type: gene
Organism: frog, western clawed
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Gene
100381129 | izumo1r.L
Type: gene
Organism: frog, African clawed
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Protein Coding Gene
MGI:1929185 | Izumo1r
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24671880 | J:210459
First Author: Vicens A
Year: 2014
Journal: Biol Reprod
Title: Coevolution of positively selected IZUMO1 and CD9 in rodents: evidence of interaction between gamete fusion proteins?
Volume: 90
Issue: 5
Pages: 113
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Publication
23651732 | J:202519
First Author: Salbaum JM
Year: 2013
Journal: Biochim Biophys Acta
Title: Mutation at the folate receptor 4 locus modulates gene expression profiles in the mouse uterus in response to periconceptional folate supplementation.
Volume: 1832
Issue: 10
Pages: 1653-61
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Allele
Izumo1r<+> | MGI:2436878
   
Name: IZUMO1 receptor, JUNO; wild type
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Publication
36972453 | J:341200
First Author: Zarin P
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Treg cells require Izumo1R to regulate γδT cell-driven inflammation in the skin.
Volume: 120
Issue: 14
Pages: e2221255120
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Allele
Izumo1r<tm1.1Salb> | MGI:5538512
Name: IZUMO1 receptor, JUNO; targeted mutation 1.1, J Michael Salbaum
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Izumo1r<tm1Salb> | MGI:3512121
Name: IZUMO1 receptor, JUNO; targeted mutation 1, J Michael Salbaum
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Izumo1r<tm2c(KOMP)Wtsi> | MGI:5792910
Name: IZUMO1 receptor, JUNO; targeted mutation 2c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Izumo1r<tm1b(KOMP)Wtsi> | MGI:5548704
Name: IZUMO1 receptor, JUNO; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Izumo1r<em1Nino> | MGI:6511751
Name: IZUMO1 receptor, JUNO; endonuclease-mediated mutation 1, Naokazu Inoue
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s), Null/knockout
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom