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Search results 1 to 100 out of 316 for Jak3

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Thomis DC
Year: 1997
Journal: J Exp Med
Title: Peripheral expression of Jak3 is required to maintain T lymphocyte function.
Volume: 185
Issue: 2
Pages: 197-206
Publication
First Author: Gurniak CB
Year: 1996
Journal: Blood
Title: Murine JAK3 is preferentially expressed in hematopoietic tissues and lymphocyte precursor cells.
Volume: 87
Issue: 8
Pages: 3151-60
Publication
First Author: Kono DH
Year: 1996
Journal: Mamm Genome
Title: Jak3 maps to chromosome 8.
Volume: 7
Issue: 6
Pages: 476-7
Publication
First Author: Park SY
Year: 1995
Journal: Immunity
Title: Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.
Volume: 3
Issue: 6
Pages: 771-82
Publication
First Author: Kumar A
Year: 1996
Journal: Oncogene
Title: Structural organization and chromosomal mapping of JAK3 locus.
Volume: 13
Issue: 9
Pages: 2009-14
Publication
First Author: Yamaoka K
Year: 2005
Journal: Blood
Title: Jak3 negatively regulates dendritic-cell cytokine production and survival.
Volume: 106
Issue: 9
Pages: 3227-33
Publication
First Author: Thomis DC
Year: 1997
Journal: Curr Opin Immunol
Title: The role of Jak3 in lymphoid development, activation, and signaling.
Volume: 9
Issue: 4
Pages: 541-7
Publication
First Author: Rivas-Caicedo A
Year: 2009
Journal: PLoS One
Title: Jak3 is involved in dendritic cell maturation and CCR7-dependent migration.
Volume: 4
Issue: 9
Pages: e7066
Publication
First Author: Lange C
Year: 2010
Journal: J Neurochem
Title: LIF-dependent JAK3 activation is not essential for retinal degeneration.
Volume: 113
Issue: 5
Pages: 1210-20
Publication
First Author: Saijo K
Year: 1997
Journal: J Exp Med
Title: Crucial role of Jak3 in negative selection of self-reactive T cells.
Volume: 185
Issue: 2
Pages: 351-6
Publication
First Author: Bellanger D
Year: 2014
Journal: Leukemia
Title: Recurrent JAK1 and JAK3 somatic mutations in T-cell prolymphocytic leukemia.
Volume: 28
Issue: 2
Pages: 417-9
Publication
First Author: Eynon EE
Year: 1999
Journal: J Immunol
Title: Distinct effects of Jak3 signaling on alphabeta and gammadelta thymocyte development.
Volume: 162
Issue: 3
Pages: 1448-59
Publication
First Author: Wen R
Year: 2001
Journal: Mol Cell Biol
Title: Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development.
Volume: 21
Issue: 2
Pages: 678-89
Publication
First Author: Chang BY
Year: 2009
Journal: J Immunol
Title: JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice.
Volume: 183
Issue: 3
Pages: 2183-92
Publication
First Author: Mangan JK
Year: 2004
Journal: Blood
Title: Mechanisms associated with IL-6-induced up-regulation of Jak3 and its role in monocytic differentiation.
Volume: 103
Issue: 11
Pages: 4093-101
Publication
First Author: Broux M
Year: 2019
Journal: Blood
Title: Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia.
Volume: 134
Issue: 16
Pages: 1323-1336
Publication
First Author: Ambriz-Peña X
Year: 2014
Journal: PLoS One
Title: Jak3 enables chemokine-dependent actin cytoskeleton reorganization by regulating cofilin and Rac/Rhoa GTPases activation.
Volume: 9
Issue: 2
Pages: e88014
Publication
First Author: Sohn SJ
Year: 1998
Journal: J Immunol
Title: Requirement for Jak3 in mature T cells: its role in regulation of T cell homeostasis.
Volume: 160
Issue: 5
Pages: 2130-8
Publication
First Author: Tortolani PJ
Year: 1995
Journal: J Immunol
Title: Regulation of JAK3 expression and activation in human B cells and B cell malignancies.
Volume: 155
Issue: 11
Pages: 5220-6
Publication
First Author: Nosaka T
Year: 1995
Journal: Science
Title: Defective lymphoid development in mice lacking Jak3.
Volume: 270
Issue: 5237
Pages: 800-2
Publication
First Author: Thomis DC
Year: 1995
Journal: Science
Title: Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3.
Volume: 270
Issue: 5237
Pages: 794-7
Publication
First Author: Rane SG
Year: 1994
Journal: Oncogene
Title: JAK3: a novel JAK kinase associated with terminal differentiation of hematopoietic cells.
Volume: 9
Issue: 8
Pages: 2415-23
Publication
First Author: Koskimies P
Year: 1997
Journal: FEBS Lett
Title: The mouse relaxin-like factor gene and its promoter are located within the 3' region of the JAK3 genomic sequence.
Volume: 419
Issue: 2-3
Pages: 186-90
Publication
First Author: Bongfen SE
Year: 2012
Journal: PLoS One
Title: An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria.
Volume: 7
Issue: 2
Pages: e31012
Publication
First Author: Baird AM
Year: 1998
Journal: J Leukoc Biol
Title: T cell development and activation in Jak3-deficient mice.
Volume: 63
Issue: 6
Pages: 669-77
Publication
First Author: Witthuhn BA
Year: 1994
Journal: Nature
Title: Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells.
Volume: 370
Issue: 6485
Pages: 153-7
Publication
First Author: Suzuki K
Year: 2000
Journal: Int Immunol
Title: Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice.
Volume: 12
Issue: 2
Pages: 123-32
Publication
First Author: Zhu MH
Year: 1998
Journal: J Biol Chem
Title: Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta.
Volume: 273
Issue: 17
Pages: 10719-25
Publication
First Author: Lv N
Year: 2009
Journal: Exp Cell Res
Title: JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-kappaB activation and the JAK/STAT pathway.
Volume: 315
Issue: 12
Pages: 2064-71
Publication
First Author: Eynon EE
Year: 1996
Journal: J Interferon Cytokine Res
Title: Disruption of cytokine signaling in lymphoid development: unique contributions of the common cytokine gamma chain and the Jak3 kinase.
Volume: 16
Issue: 9
Pages: 677-84
Publication
First Author: Remenyi J
Year: 2021
Journal: Sci Rep
Title: Generation of a chemical genetic model for JAK3.
Volume: 11
Issue: 1
Pages: 10093
Publication
First Author: Grossman WJ
Year: 1999
Journal: Blood
Title: Dysregulated myelopoiesis in mice lacking Jak3.
Volume: 94
Issue: 3
Pages: 932-9
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Implevit.
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Deposuit.
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for potentes.
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for distortion.
Publication
First Author: Uckun FM
Year: 2007
Journal: Anticancer Agents Med Chem
Title: Targeting JAK3 tyrosine kinase-linked signal transduction pathways with rationally-designed inhibitors.
Volume: 7
Issue: 6
Pages: 612-23
Publication      
First Author: Choi JH
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for thistle2.
Publication
First Author: Mayack SR
Year: 2006
Journal: J Immunol
Title: Cutting edge: an alternative pathway of CD4+ T cell differentiation is induced following activation in the absence of gamma-chain-dependent cytokine signals.
Volume: 176
Issue: 4
Pages: 2059-63
Publication
First Author: Trieu VN
Year: 2000
Journal: Biochem Biophys Res Commun
Title: A specific inhibitor of janus kinase-3 increases survival in a transgenic mouse model of amyotrophic lateral sclerosis.
Volume: 267
Issue: 1
Pages: 22-5
Publication
First Author: Tibbles HE
Year: 2001
Journal: J Biol Chem
Title: Role of a JAK3-dependent biochemical signaling pathway in platelet activation and aggregation.
Volume: 276
Issue: 21
Pages: 17815-22
Publication
First Author: Bunting KD
Year: 1998
Journal: Nat Med
Title: Restoration of lymphocyte function in Janus kinase 3-deficient mice by retroviral-mediated gene transfer.
Volume: 4
Issue: 1
Pages: 58-64
Publication
First Author: Malaviya R
Year: 2001
Journal: Immunity
Title: Role of Janus kinase 3 in mast cell-mediated innate immunity against gram-negative bacteria.
Volume: 15
Issue: 2
Pages: 313-21
Publication
First Author: Shi M
Year: 2009
Journal: J Immunol
Title: Cell cycle progression following naive T cell activation is independent of Jak3/common gamma-chain cytokine signals.
Volume: 183
Issue: 7
Pages: 4493-501
Publication
First Author: Xu W
Year: 2012
Journal: PLoS One
Title: Hemagglutinin from the H5N1 virus activates Janus kinase 3 to dysregulate innate immunity.
Volume: 7
Issue: 2
Pages: e31721
Publication
First Author: Mishra J
Year: 2013
Journal: J Biol Chem
Title: Role of Janus kinase 3 in mucosal differentiation and predisposition to colitis.
Volume: 288
Issue: 44
Pages: 31795-806
Publication
First Author: Wang H
Year: 2013
Journal: J Immunol
Title: The role of JAK-3 in regulating TLR-mediated inflammatory cytokine production in innate immune cells.
Volume: 191
Issue: 3
Pages: 1164-74
Publication
First Author: Verbsky JW
Year: 2002
Journal: J Immunol
Title: Nonhematopoietic expression of Janus kinase 3 is required for efficient recruitment of Th2 lymphocytes and eosinophils in OVA-induced airway inflammation.
Volume: 168
Issue: 5
Pages: 2475-82
Publication
First Author: Mishra J
Year: 2015
Journal: J Biol Chem
Title: Role of Janus Kinase 3 in Predisposition to Obesity-associated Metabolic Syndrome.
Volume: 290
Issue: 49
Pages: 29301-12
Publication
First Author: Li L
Year: 1999
Journal: J Immunol
Title: Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells.
Volume: 162
Issue: 5
Pages: 2477-87
Publication
First Author: Carpino N
Year: 2004
Journal: Mol Cell Biol
Title: Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development.
Volume: 24
Issue: 6
Pages: 2584-92
Publication
First Author: Brown MP
Year: 1999
Journal: Blood
Title: Reconstitution of early lymphoid proliferation and immune function in Jak3-deficient mice by interleukin-3.
Volume: 94
Issue: 6
Pages: 1906-14
Publication
First Author: Rivera-Munoz P
Year: 2018
Journal: Blood Adv
Title: Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models.
Volume: 2
Issue: 13
Pages: 1616-1627
Publication
First Author: Thomis DC
Year: 1997
Journal: J Immunol
Title: T cells from Jak3-deficient mice have intact TCR signaling, but increased apoptosis.
Volume: 159
Issue: 10
Pages: 4708-19
Publication
First Author: García-Zepeda EA
Year: 2007
Journal: Immunology
Title: Janus kinase 3-deficient T lymphocytes have an intrinsic defect in CCR7-mediated homing to peripheral lymphoid organs.
Volume: 122
Issue: 2
Pages: 247-60
Publication
First Author: Gurniak CB
Year: 1997
Journal: DNA Cell Biol
Title: Genomic structure and promoter region of the murine Janus-family tyrosine kinase, Jak3.
Volume: 16
Issue: 1
Pages: 85-94
Publication
First Author: Hechinger AK
Year: 2015
Journal: Blood
Title: Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD.
Volume: 125
Issue: 3
Pages: 570-80
Publication
First Author: Murata Y
Year: 2002
Journal: Int Immunol
Title: The conversion of redox status of peritoneal macrophages during pathological progression of spontaneous inflammatory bowel disease in Janus family tyrosine kinase 3(-/-) and IL-2 receptor gamma(-/-) mice.
Volume: 14
Issue: 6
Pages: 627-36
Publication
First Author: Nakayama J
Year: 2009
Journal: Blood
Title: BLNK suppresses pre-B-cell leukemogenesis through inhibition of JAK3.
Volume: 113
Issue: 7
Pages: 1483-92
Publication
First Author: Prinz I
Year: 2006
Journal: Nat Immunol
Title: Visualization of the earliest steps of gammadelta T cell development in the adult thymus.
Volume: 7
Issue: 9
Pages: 995-1003
Publication
First Author: Shi M
Year: 2008
Journal: Immunity
Title: Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation.
Volume: 28
Issue: 6
Pages: 763-73
Publication
First Author: Aringer M
Year: 1999
Journal: Life Sci
Title: Janus kinases and their role in growth and disease.
Volume: 64
Issue: 24
Pages: 2173-86
Publication
First Author: Ghoreschi K
Year: 2011
Journal: J Immunol
Title: Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).
Volume: 186
Issue: 7
Pages: 4234-43
Publication
First Author: Mishra J
Year: 2017
Journal: J Biol Chem
Title: Janus kinase 3 regulates adherens junctions and epithelial mesenchymal transition through β-catenin.
Volume: 292
Issue: 40
Pages: 16406-16419
Publication
First Author: Jahn T
Year: 2007
Journal: Blood
Title: Direct interaction between Kit and the interleukin-7 receptor.
Volume: 110
Issue: 6
Pages: 1840-7
Publication
First Author: Wei C
Year: 2000
Journal: J Immunol
Title: Murine pro-B cells require IL-7 and its receptor complex to up-regulate IL-7R alpha, terminal deoxynucleotidyltransferase, and c mu expression.
Volume: 164
Issue: 4
Pages: 1961-70
Publication
First Author: Yin T
Year: 1995
Journal: J Biol Chem
Title: Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases.
Volume: 270
Issue: 35
Pages: 20497-502
Publication
First Author: Babon JJ
Year: 2014
Journal: Biochem J
Title: The molecular regulation of Janus kinase (JAK) activation.
Volume: 462
Issue: 1
Pages: 1-13
Publication
First Author: Duré M
Year: 2009
Journal: Mol Immunol
Title: IL-2 signaling prevents T cell anergy by inhibiting the expression of anergy-inducing genes.
Volume: 46
Issue: 5
Pages: 999-1006
Publication
First Author: Rochman Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7-induced signaling.
Volume: 107
Issue: 45
Pages: 19455-60
Publication  
First Author: Huang K
Year: 2018
Journal: Biol Open
Title: JAK signaling regulates germline cyst breakdown and primordial follicle formation in mice.
Volume: 7
Issue: 1
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Zeng M
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for mount_tai
Publication      
First Author: Wang KW
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for thistle
Publication      
First Author: Zeng M
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for citron
Publication
First Author: Soldevila G
Year: 2004
Journal: Immunology
Title: Impaired chemokine-induced migration during T-cell development in the absence of Jak 3.
Volume: 112
Issue: 2
Pages: 191-200
Publication
First Author: Dillon SR
Year: 2002
Journal: Int Immunol
Title: Partial restoration of B cell development in Jak-3(-/-) mice achieved by co-expression of IgH and E(mu)-myc transgenes.
Volume: 14
Issue: 8
Pages: 893-904
Publication
First Author: Nithichanon A
Year: 2017
Journal: Immunology
Title: Boosting of post-exposure human T-cell and B-cell recall responses in vivo by Burkholderia pseudomallei-related proteins.
Volume: 151
Issue: 1
Pages: 98-109