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Search results 1 to 63 out of 63 for Jaml

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Junctional adhesion molecule-like (JAML) contains 2 extracellular immunoglobulin-like domains, a transmembrane segment, and a cytoplasmic tail. JAML mRNA is expressed in hematopoietic tissues and is localised at the cell plasma membrane in the areas of cell-cell contacts []. It is a receptor that controls the migration and activation of the epithelial gamma-delta T cells through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells []. During acute inflammation, neutrophils infiltrate the intestinal mucosa. JAML can be cleaved from the neutrophil surface by zinc metalloproteases during theneutrophil transepithelial migration (TEM) []. These neutrophil-derived soluble JAML can bind to the epithelial tight junction protein coxsackie-adenovirus receptor (CAR) and decrease epithelial proliferation, inhibiting wound repair and promoting the recruitment of leukocytes [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Witherden DA
Year: 2010
Journal: Science
Title: The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation.
Volume: 329
Issue: 5996
Pages: 1205-10
Publication
First Author: Fu Y
Year: 2020
Journal: Cell Metab
Title: Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism.
Volume: 32
Issue: 6
Pages: 1052-1062.e8
Publication
First Author: Weber DA
Year: 2014
Journal: Mucosal Immunol
Title: Neutrophil-derived JAML inhibits repair of intestinal epithelial injury during acute inflammation.
Volume: 7
Issue: 5
Pages: 1221-32
Publication
First Author: Verdino P
Year: 2010
Journal: Science
Title: The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K.
Volume: 329
Issue: 5996
Pages: 1210-4
Protein
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
Publication
First Author: Moog-Lutz C
Year: 2003
Journal: Blood
Title: JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells.
Volume: 102
Issue: 9
Pages: 3371-8
Protein
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
Publication
First Author: Mirza M
Year: 2007
Journal: Endocrinology
Title: Coxsackievirus and adenovirus receptor is up-regulated in migratory germ cells during passage of the blood-testis barrier.
Volume: 148
Issue: 11
Pages: 5459-69
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:6457455
Assay Type: RNA in situ
Annotation Date: 2020-12-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757723
Stage: TS23
Assay Id: MGI:6488589
Age: embryonic day 15.5
Specimen Label: S1 Table B71
Detected: false
Specimen Num: 1
Publication
First Author: Inoue SI
Year: 2017
Journal: Hum Mol Genet
Title: Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.
Volume: 26
Issue: 23
Pages: 4715-4727
Publication
First Author: Gu Z
Year: 2015
Journal: PLoS One
Title: Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Volume: 10
Issue: 3
Pages: e0121550
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
Publication
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
Publication      
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Allele
Name: junction adhesion molecule like; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout