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Search results 1 to 66 out of 66 for Jaml

0.013s

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
120425 | JAML
Type: gene
Organism: human
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Gene
315610 | Jaml
Type: gene
Organism: rat
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Gene
610790 | JAML
Type: gene
Organism: dog, domestic
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Gene
451582 | JAML
Type: gene
Organism: chimpanzee
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Gene
509575 | JAML
Type: gene
Organism: cattle
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Gene
419777 | JAML
Type: gene
Organism: chicken
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Gene
704919 | JAML
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR029871 | JAML
Type: Family
Description: Junctional adhesion molecule-like (JAML) contains 2 extracellular immunoglobulin-like domains, a transmembrane segment, and a cytoplasmic tail. JAML mRNA is expressed in hematopoietic tissues and is localised at the cell plasma membrane in the areas of cell-cell contacts []. It is a receptor that controls the migration and activation of the epithelial gamma-delta T cells through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells []. During acute inflammation, neutrophils infiltrate the intestinal mucosa. JAML can be cleaved from the neutrophil surface by zinc metalloproteases during theneutrophil transepithelial migration (TEM) []. These neutrophil-derived soluble JAML can bind to the epithelial tight junction protein coxsackie-adenovirus receptor (CAR) and decrease epithelial proliferation, inhibiting wound repair and promoting the recruitment of leukocytes [].
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Protein Coding Gene
MGI:2685484 | Jaml
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20813954 | J:163519
First Author: Witherden DA
Year: 2010
Journal: Science
Title: The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation.
Volume: 329
Issue: 5996
Pages: 1205-10
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Publication
35708906 | J:360473
 
First Author: Huang W
Year: 2022
Journal: JCI Insight
Title: JAML promotes acute kidney injury mainly through a macrophage-dependent mechanism.
Volume: 7
Issue: 14
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Publication
24621992 | -
First Author: Weber DA
Year: 2014
Journal: Mucosal Immunol
Title: Neutrophil-derived JAML inhibits repair of intestinal epithelial injury during acute inflammation.
Volume: 7
Issue: 5
Pages: 1221-32
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Publication
33186558 | J:300243
First Author: Fu Y
Year: 2020
Journal: Cell Metab
Title: Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism.
Volume: 32
Issue: 6
Pages: 1052-1062.e8
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Publication
20813955 | J:163518
First Author: Verdino P
Year: 2010
Journal: Science
Title: The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K.
Volume: 329
Issue: 5996
Pages: 1210-4
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Protein
A0A1L1SSJ0
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
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Publication
12869515 | -
First Author: Moog-Lutz C
Year: 2003
Journal: Blood
Title: JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells.
Volume: 102
Issue: 9
Pages: 3371-8
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Protein
A0A1L1STQ5
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: true
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Protein
Q80UL9
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
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Publication
17690169 | J:177153
First Author: Mirza M
Year: 2007
Journal: Endocrinology
Title: Coxsackievirus and adenovirus receptor is up-regulated in migratory germ cells during passage of the blood-testis barrier.
Volume: 148
Issue: 11
Pages: 5459-69
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Protein Coding Gene
MGP_CAROLIEiJ_G0032137 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034729 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034710 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034637 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034412 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2685484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035222 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033734 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034384 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034543 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034528 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035243 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033439 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033847 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015006 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033275 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:6457455
Assay Type: RNA in situ
Annotation Date: 2020-12-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757723
Stage: TS23
Assay Id: MGI:6488589
Age: embryonic day 15.5
Specimen Label: S1 Table B71
Detected: false
Specimen Num: 1
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Publication
28973166 | J:253459
First Author: Inoue SI
Year: 2017
Journal: Hum Mol Genet
Title: Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.
Volume: 26
Issue: 23
Pages: 4715-4727
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Publication
25826454 | J:229257
First Author: Gu Z
Year: 2015
Journal: PLoS One
Title: Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Volume: 10
Issue: 3
Pages: e0121550
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Publication
20562862 | J:161922
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
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Publication
12477932 | J:82808
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
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Publication
- | J:171883
     
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Allele
Jaml<em1Smoc> | MGI:7290631
Name: junction adhesion molecule like; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6429026 | C57BL/6JSmoc-Jaml<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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