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Search results 1 to 100 out of 478 for Junb

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Hits by Category

Hits by Strain

Type Details Score
Gene
3726 | JUNB
Type: gene
Organism: human
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Gene
733713 | junb
Type: gene
Organism: frog, western clawed
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Gene
24517 | Junb
Type: gene
Organism: rat
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Gene
468739 | JUNB
Type: gene
Organism: chimpanzee
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Gene
514246 | JUNB
Type: gene
Organism: cattle
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Gene
100856456 | JUNB
Type: gene
Organism: dog, domestic
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Gene
717837 | JUNB
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR029822 | JunB
Type: Family
Description: Transcription factor JunB is a member of the transcription factor activator protein (AP)-1 family, comprising Jun (c-Jun, JunB, and JunD), Fos (c-Fos, FosB, Fra1, and Fra2), ATF (ATFa, ATF-2 and ATF-3) and JDP (JDP-1 and JDP-2) family members []. They are basic leucine zipper transcription factors that play a central role in regulating gene transcription in various biological processes []. JunB may serve as a biomarkers for prognosis of breast cancer [].AP-1 proteins have a α-helical bZIP domain, which contains a basic DNA-binding region and regularly spaced leucine residues known as the leucine zipper motif []. They have similar protein structure and can either form homodimers or form heterodimers with other AP-1 proteins (predominantly with Jun proteins), which can then bind to TRE-like sequences (consensus sequence 5'-TGAG/CTCA-3') []. Each of these proteins are expressed in different tissues and can be regulated in different ways, which means that every cell type has a complex mixture of AP-1 dimers with subtly different functions [].
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Protein Coding Gene
MGI:96647 | Junb
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q569U6
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q3TXR4
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q3U2Y0
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
P09450
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Publication
8530030 | J:28017
First Author: Phinney DG
Year: 1995
Journal: Genomics
Title: Complex genetic organization of junB: multiple blocks of flanking evolutionarily conserved sequence at the murine and human junB loci.
Volume: 28
Issue: 2
Pages: 228-34
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Protein
Q3U0S8
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Publication
24073962 | -
 
First Author: Kharman-Biz A
Year: 2013
Journal: BMC Cancer
Title: Expression of activator protein-1 (AP-1) family members in breast cancer.
Volume: 13
Pages: 441
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Gene
117038792 | LOC117038792
Type: gene
Organism: human
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Publication
15564374 | -
First Author: Hess J
Year: 2004
Journal: J Cell Sci
Title: AP-1 subunits: quarrel and harmony among siblings.
Volume: 117
Issue: Pt 25
Pages: 5965-73
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Publication
23787991 | -
First Author: Murphy TL
Year: 2013
Journal: Nat Rev Immunol
Title: Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks.
Volume: 13
Issue: 7
Pages: 499-509
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Publication
12424143 | -
First Author: Reddy SP
Year: 2002
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Role and regulation of activator protein-1 in toxicant-induced responses of the lung.
Volume: 283
Issue: 6
Pages: L1161-78
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Publication
11726656 | J:74641
First Author: Jacobs-Helber SM
Year: 2002
Journal: J Biol Chem
Title: Role of JunB in erythroid differentiation.
Volume: 277
Issue: 7
Pages: 4859-66
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Publication
1630451 | J:1470
First Author: Apel I
Year: 1992
Journal: Mol Cell Biol
Title: Regulation of the junB gene by v-src.
Volume: 12
Issue: 8
Pages: 3356-64
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Publication
29234109 | J:287427
First Author: Yamazaki S
Year: 2017
Journal: Sci Rep
Title: The AP-1 transcription factor JunB is required for Th17 cell differentiation.
Volume: 7
Issue: 1
Pages: 17402
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Publication
17297445 | J:125545
First Author: Ott RG
Year: 2007
Journal: Oncogene
Title: JunB is a gatekeeper for B-lymphoid leukemia.
Volume: 26
Issue: 33
Pages: 4863-71
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Publication
10022836 | J:53304
First Author: Schorpp-Kistner M
Year: 1999
Journal: EMBO J
Title: JunB is essential for mammalian placentation.
Volume: 18
Issue: 4
Pages: 934-48
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Publication
11163237 | J:67298
First Author: Passegué E
Year: 2001
Journal: Cell
Title: Chronic myeloid leukemia with increased granulocyte progenitors in mice lacking junB expression in the myeloid lineage.
Volume: 104
Issue: 1
Pages: 21-32
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Publication
35837408 | J:361190
 
First Author: Hsieh T
Year: 2022
Journal: Front Immunol
Title: JunB Is Critical for Survival of T Helper Cells.
Volume: 13
Pages: 901030
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Publication
11818961 | J:75359
First Author: Passegué E
Year: 2002
Journal: Nat Genet
Title: JunB can substitute for Jun in mouse development and cell proliferation.
Volume: 30
Issue: 2
Pages: 158-66
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Publication
30224386 | J:267906
First Author: Chen S
Year: 2018
Journal: J Exp Med
Title: USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein.
Volume: 215
Issue: 11
Pages: 2850-2867
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Publication
28555647 | J:244764
 
First Author: Hasan Z
Year: 2017
Journal: Nat Commun
Title: JunB is essential for IL-23-dependent pathogenicity of Th17 cells.
Volume: 8
Pages: 15628
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Publication
25472994 | J:230687
First Author: Fontana MF
Year: 2015
Journal: J Immunol
Title: JUNB is a key transcriptional modulator of macrophage activation.
Volume: 194
Issue: 1
Pages: 177-86
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Publication
8108135 | J:17030
First Author: Coffer P
Year: 1994
Journal: Oncogene
Title: junB promoter regulation: Ras mediated transactivation by c-Ets-1 and c-Ets-2.
Volume: 9
Issue: 3
Pages: 911-21
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Publication
31285535 | J:290370
First Author: Katagiri T
Year: 2019
Journal: Mucosal Immunol
Title: JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling.
Volume: 12
Issue: 5
Pages: 1104-1117
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Publication
3422745 | J:9056
First Author: Ryder K
Year: 1988
Journal: Proc Natl Acad Sci U S A
Title: A gene activated by growth factors is related to the oncogene v-jun.
Volume: 85
Issue: 5
Pages: 1487-91
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Publication
38191667 | J:360055
First Author: Zhang X
Year: 2024
Journal: Nat Metab
Title: Depletion of JunB increases adipocyte thermogenic capacity and ameliorates diet-induced insulin resistance.
Volume: 6
Issue: 1
Pages: 78-93
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Publication
19561194 | J:173026
First Author: Ponticos M
Year: 2009
Journal: Nucleic Acids Res
Title: JunB mediates enhancer/promoter activity of COL1A2 following TGF-beta induction.
Volume: 37
Issue: 16
Pages: 5378-89
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Publication
39425978 | J:361014
     
First Author: Sarkar S
Year: 2024
Journal: Int Immunol
Title: JunB is required for CD8+ T cell responses to acute infections.
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Publication
17982078 | J:153861
First Author: Textor B
Year: 2007
Journal: J Immunol
Title: JunB is required for IgE-mediated degranulation and cytokine release of mast cells.
Volume: 179
Issue: 10
Pages: 6873-80
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Publication
24027048 | J:231996
First Author: Braun J
Year: 2014
Journal: Int J Cancer
Title: Loss of stromal JUNB does not affect tumor growth and angiogenesis.
Volume: 134
Issue: 6
Pages: 1511-6
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Publication
15507213 | J:94778
First Author: Passegué E
Year: 2004
Journal: Cell
Title: JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells.
Volume: 119
Issue: 3
Pages: 431-43
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Publication
31017652 | J:289190
First Author: Wu J
Year: 2019
Journal: FEBS Lett
Title: Regulatory T cells sense effector T-cell activation through synchronized JunB expression.
Volume: 593
Issue: 10
Pages: 1020-1029
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Publication
18641637 | J:145478
First Author: Meixner A
Year: 2008
Journal: Nat Cell Biol
Title: Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation.
Volume: 10
Issue: 8
Pages: 1003-11
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Publication
30559442 | J:268329
First Author: Koizumi SI
Year: 2018
Journal: Nat Commun
Title: JunB regulates homeostasis and suppressive functions of effector regulatory T cells.
Volume: 9
Issue: 1
Pages: 5344
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Publication
17255940 | J:119917
First Author: Schmidt D
Year: 2007
Journal: EMBO J
Title: Critical role for NF-kappaB-induced JunB in VEGF regulation and tumor angiogenesis.
Volume: 26
Issue: 3
Pages: 710-9
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Publication
30143626 | J:266405
First Author: Singh K
Year: 2018
Journal: Nat Commun
Title: JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin.
Volume: 9
Issue: 1
Pages: 3425
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Publication
1708123 | J:20564
First Author: de Groot RP
Year: 1991
Journal: Nucleic Acids Res
Title: Activation of junB by PKC and PKA signal transduction through a novel cis-acting element.
Volume: 19
Issue: 4
Pages: 775-81
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Publication
23921639 | J:210726
First Author: Salem T
Year: 2013
Journal: Nucleic Acids Res
Title: Chromatin loop organization of the junb locus in mouse dendritic cells.
Volume: 41
Issue: 19
Pages: 8908-25
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Publication
20551518 | J:163787
First Author: Licht AH
Year: 2010
Journal: J Clin Invest
Title: Junb regulates arterial contraction capacity, cellular contractility, and motility via its target Myl9 in mice.
Volume: 120
Issue: 7
Pages: 2307-18
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Publication
16439969 | J:106790
First Author: Florin L
Year: 2006
Journal: J Invest Dermatol
Title: Delayed wound healing and epidermal hyperproliferation in mice lacking JunB in the skin.
Volume: 126
Issue: 4
Pages: 902-11
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Publication
28096474 | J:247207
First Author: Yoshitomi Y
Year: 2017
Journal: J Cell Sci
Title: JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin.
Volume: 130
Issue: 5
Pages: 916-926
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Publication
17158955 | J:119115
First Author: Licht AH
Year: 2006
Journal: J Cell Biol
Title: JunB is required for endothelial cell morphogenesis by regulating core-binding factor beta.
Volume: 175
Issue: 6
Pages: 981-91
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Publication
1459456 | J:3411
First Author: Bossy-Wetzel E
Year: 1992
Journal: Genes Dev
Title: Transcription factors junB and c-jun are selectively up-regulated and functionally implicated in fibrosarcoma development.
Volume: 6
Issue: 12A
Pages: 2340-51
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Publication
8197114 | J:18618
First Author: Wang H
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Adipocyte differentiation selectively represses the serum inducibility of c-jun and junB by reversible transcription-dependent mechanisms.
Volume: 91
Issue: 11
Pages: 4649-53
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Publication
19345332 | J:147433
First Author: Santaguida M
Year: 2009
Journal: Cancer Cell
Title: JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.
Volume: 15
Issue: 4
Pages: 341-52
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Publication
22391036 | J:185061
First Author: Gervasi M
Year: 2012
Journal: J Cell Biol
Title: JunB contributes to Id2 repression and the epithelial-mesenchymal transition in response to transforming growth factor-β.
Volume: 196
Issue: 5
Pages: 589-603
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Publication
14769860 | J:88126
First Author: Kenner L
Year: 2004
Journal: J Cell Biol
Title: Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects.
Volume: 164
Issue: 4
Pages: 613-23
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Publication
21371435 | J:171943
First Author: Son JS
Year: 2011
Journal: Biochem Biophys Res Commun
Title: JunB and c-Rel cooperatively enhance Foxp3 expression during induced regulatory T cell differentiation.
Volume: 407
Issue: 1
Pages: 141-7
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Publication
19918056 | J:155575
First Author: Pflegerl P
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.
Volume: 106
Issue: 48
Pages: 20423-8
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Publication
34469740 | J:314211
First Author: Maity P
Year: 2021
Journal: Cell Rep
Title: Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging.
Volume: 36
Issue: 9
Pages: 109634
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Publication
28824171 | J:251659
First Author: Carr TM
Year: 2017
Journal: Nat Commun
Title: JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation.
Volume: 8
Issue: 1
Pages: 301
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Publication
20200942 | J:183368
First Author: Zhao L
Year: 2010
Journal: J Bone Miner Res
Title: Smurf1 inhibits mesenchymal stem cell proliferation and differentiation into osteoblasts through JunB degradation.
Volume: 25
Issue: 6
Pages: 1246-56
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Publication
16365389 | J:126244
First Author: Nausch N
Year: 2006
Journal: J Immunol
Title: Cutting edge: the AP-1 subunit JunB determines NK cell-mediated target cell killing by regulation of the NKG2D-ligand RAE-1epsilon.
Volume: 176
Issue: 1
Pages: 7-11
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Publication
25595785 | J:345370
First Author: Hwang JS
Year: 2015
Journal: J Immunol
Title: NFAT1 and JunB cooperatively regulate IL-31 gene expression in CD4+ T cells in health and disease.
Volume: 194
Issue: 4
Pages: 1963-74
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Publication
8036018 | J:19426
First Author: Phinney DG
Year: 1994
Journal: Oncogene
Title: Quantitative analysis of the contribution made by 5'-flanking and 3'-flanking sequences to the transcriptional regulation of junB by growth factors.
Volume: 9
Issue: 8
Pages: 2353-62
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Gene
117038790 | LOC117038790
Type: gene
Organism: human
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Gene
117038791 | LOC117038791
Type: gene
Organism: human
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Publication
19816943 | J:239201
First Author: Mallakin A
Year: 2010
Journal: Int J Cancer
Title: The Arf-inducing transcription factor Dmp1 encodes a transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1.
Volume: 126
Issue: 6
Pages: 1403-16
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Publication
1793595 | J:453
First Author: Alcivar AA
Year: 1991
Journal: Mol Reprod Dev
Title: junD mRNA expression differs from c-jun and junB mRNA expression during male germinal cell differentiation.
Volume: 30
Issue: 3
Pages: 187-93
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Publication
15187104 | J:90832
First Author: Voice J
Year: 2004
Journal: J Immunol
Title: c-Maf and JunB mediation of Th2 differentiation induced by the type 2 G protein-coupled receptor (VPAC2) for vasoactive intestinal peptide.
Volume: 172
Issue: 12
Pages: 7289-96
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Publication
8537375 | J:30563
First Author: Brown RT
Year: 1995
Journal: J Biol Chem
Title: An acute phase response factor/NF-kappa B site downstream of the junB gene that mediates responsiveness to interleukin-6 in a murine plasmacytoma.
Volume: 270
Issue: 52
Pages: 31129-35
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Publication
8757326 | J:34895
First Author: Mondino A
Year: 1996
Journal: J Immunol
Title: Defective transcription of the IL-2 gene is associated with impaired expression of c-Fos, FosB, and JunB in anergic T helper 1 cells.
Volume: 157
Issue: 5
Pages: 2048-57
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Publication
12456639 | J:80663
First Author: Hartenstein B
Year: 2002
Journal: EMBO J
Title: Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB.
Volume: 21
Issue: 23
Pages: 6321-9
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Publication
8650001 | J:33045
First Author: Schorpp M
Year: 1996
Journal: Nucleic Acids Res
Title: The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice.
Volume: 24
Issue: 9
Pages: 1787-8
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Publication
24200694 | J:207773
First Author: Thomsen MK
Year: 2013
Journal: J Clin Invest
Title: JUNB/AP-1 controls IFN-γ during inflammatory liver disease.
Volume: 123
Issue: 12
Pages: 5258-68
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Publication
14576352 | J:86717
First Author: Hess J
Year: 2003
Journal: J Cell Sci
Title: Defective endochondral ossification in mice with strongly compromised expression of JunB.
Volume: 116
Issue: Pt 22
Pages: 4587-96
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Publication
7877445 | J:21224
First Author: Kavety B
Year: 1994
Journal: Brain Res Mol Brain Res
Title: Genomic structure and mapping of precerebellin and a precerebellin-related gene.
Volume: 27
Issue: 1
Pages: 152-6
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Publication
15358865 | J:93082
First Author: Gao M
Year: 2004
Journal: Science
Title: Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch.
Volume: 306
Issue: 5694
Pages: 271-5
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Publication
1887331 | J:11405
First Author: Shapiro M
Year: 1991
Journal: Somat Cell Mol Genet
Title: Genetic mapping in the mouse of four loci related to the jun family of transcriptional activators.
Volume: 17
Issue: 4
Pages: 341-7
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Publication
21809421 | J:190204
First Author: Zhao L
Year: 2011
Journal: Stem Cells
Title: Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1.
Volume: 29
Issue: 10
Pages: 1601-10
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Publication
11013214 | J:150402
First Author: Suzu S
Year: 2000
Journal: EMBO J
Title: p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction.
Volume: 19
Issue: 19
Pages: 5114-22
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Publication
31644908 | J:280496
First Author: Uluçkan Ö
Year: 2019
Journal: Cell Rep
Title: Cutaneous Immune Cell-Microbiota Interactions Are Controlled by Epidermal JunB/AP-1.
Volume: 29
Issue: 4
Pages: 844-859.e3
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Publication
16163348 | J:116380
First Author: Zenz R
Year: 2005
Journal: Nature
Title: Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins.
Volume: 437
Issue: 7057
Pages: 369-75
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Publication
19995970 | J:155815
First Author: Schonthaler HB
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis.
Volume: 106
Issue: 50
Pages: 21264-9
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Publication
27992400 | J:240632
First Author: Beyaz S
Year: 2017
Journal: Nat Immunol
Title: The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells.
Volume: 18
Issue: 2
Pages: 184-195
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Publication
35788494 | J:354110
First Author: Mellor LF
Year: 2022
Journal: Ann Rheum Dis
Title: Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease.
Volume: 81
Issue: 10
Pages: 1400-8
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Publication
25774663 | J:229637
First Author: Schreiner B
Year: 2015
Journal: PLoS One
Title: Deletion of Jun proteins in adult oligodendrocytes does not perturb cell survival, or myelin maintenance in vivo.
Volume: 10
Issue: 3
Pages: e0120454
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Publication
21540289 | J:174899
First Author: Pinent M
Year: 2011
Journal: Endocrinology
Title: Adipose triglyceride lipase and hormone-sensitive lipase are involved in fat loss in JunB-deficient mice.
Volume: 152
Issue: 7
Pages: 2678-89
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Publication
8364887 | J:21579
First Author: Kim TA
Year: 1993
Journal: Cancer Lett
Title: Transforming growth factor beta 1-induced delay of cell cycle progression and its association with growth-related gene expression in mouse fibroblasts.
Volume: 71
Issue: 1-3
Pages: 125-32
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Publication
12220541 | J:79339
First Author: Gong P
Year: 2002
Journal: Arch Biochem Biophys
Title: Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite.
Volume: 405
Issue: 2
Pages: 265-74
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Publication
25526087 | J:235114
First Author: Thomsen MK
Year: 2015
Journal: Cell Death Differ
Title: Loss of JUNB/AP-1 promotes invasive prostate cancer.
Volume: 22
Issue: 4
Pages: 574-82
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Publication
17041602 | J:115331
First Author: Steidl U
Year: 2006
Journal: Nat Genet
Title: Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.
Volume: 38
Issue: 11
Pages: 1269-77
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Publication
11456449 | J:70738
First Author: Ma GT
Year: 2001
Journal: Dev Biol
Title: Nodal regulates trophoblast differentiation and placental development.
Volume: 236
Issue: 1
Pages: 124-35
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Publication
25013898 | J:219038
First Author: Schlederer M
Year: 2014
Journal: PLoS One
Title: Reliable quantification of protein expression and cellular localization in histological sections.
Volume: 9
Issue: 7
Pages: e100822
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Publication
16699069 | J:116440
First Author: Alfonso-Jaume MA
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac ischemia-reperfusion injury induces matrix metalloproteinase-2 expression through the AP-1 components FosB and JunB.
Volume: 291
Issue: 4
Pages: H1838-46
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Publication
30183689 | J:271169
First Author: Wang Y
Year: 2018
Journal: J Clin Invest
Title: SMAD4 promotes TGF-β-independent NK cell homeostasis and maturation and antitumor immunity.
Volume: 128
Issue: 11
Pages: 5123-5136
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Publication
19933155 | J:154733
First Author: Guinea-Viniegra J
Year: 2009
Journal: Genes Dev
Title: TNFalpha shedding and epidermal inflammation are controlled by Jun proteins.
Volume: 23
Issue: 22
Pages: 2663-74
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Publication
19289495 | J:148987
First Author: Abell AN
Year: 2009
Journal: Mol Cell Biol
Title: Trophoblast stem cell maintenance by fibroblast growth factor 4 requires MEKK4 activation of Jun N-terminal kinase.
Volume: 29
Issue: 10
Pages: 2748-61
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Publication
2104845 | J:33104
First Author: Li L
Year: 1990
Journal: J Biol Chem
Title: Different members of the jun proto-oncogene family exhibit distinct patterns of expression in response to type beta transforming growth factor.
Volume: 265
Issue: 3
Pages: 1556-62
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Protein Coding Gene
MGP_CAROLIEiJ_G0031321 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033884 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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