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Search results 1 to 100 out of 377 for Jund

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0.766s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: Transcription factor JunD is a member of the transcription factor activator protein (AP)-1 family, comprising Jun (c-Jun, JunB, and JunD), Fos (c-Fos, FosB, Fra1, and Fra2), ATF (ATFa, ATF-2 and ATF-3) and JDP (JDP-1 and JDP-2) family members []. They are basic leucine zipper transcription factors that play a central role in regulating gene transcription in various biological processes []. This entry also includes transcription factor AP-1 (Jra) from Drosophila, which recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' and has a role in dorsal closure [, , ].AP-1 proteins have a α-helical bZIP domain, which contains a basic DNA-binding region and regularly spaced leucine residues known as the leucine zipper motif []. They have similar protein structure and can either form homodimers or form heterodimers with other AP-1 proteins (predominantly with Jun proteins), which can then bind to TRE-like sequences (consensus sequence 5'-TGAG/CTCA-3') []. Each of these proteins are expressed in different tissues and can be regulated in different ways, which means that every cell type has a complex mixture of AP-1 dimers with subtly different functions [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 341  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
Publication
First Author: Zhang K
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: Drosophila homolog of the mammalian jun oncogene is expressed during embryonic development and activates transcription in mammalian cells.
Volume: 87
Issue: 16
Pages: 6281-5
Publication
First Author: Perkins KK
Year: 1990
Journal: Genes Dev
Title: The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor.
Volume: 4
Issue: 5
Pages: 822-34
Publication
First Author: Kockel L
Year: 1997
Journal: Genes Dev
Title: Jun in Drosophila development: redundant and nonredundant functions and regulation by two MAPK signal transduction pathways.
Volume: 11
Issue: 13
Pages: 1748-58
Publication
First Author: Hess J
Year: 2004
Journal: J Cell Sci
Title: AP-1 subunits: quarrel and harmony among siblings.
Volume: 117
Issue: Pt 25
Pages: 5965-73
Publication
First Author: Murphy TL
Year: 2013
Journal: Nat Rev Immunol
Title: Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks.
Volume: 13
Issue: 7
Pages: 499-509
Publication
First Author: Reddy SP
Year: 2002
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Role and regulation of activator protein-1 in toxicant-induced responses of the lung.
Volume: 283
Issue: 6
Pages: L1161-78
Publication
First Author: Hirai SI
Year: 1989
Journal: EMBO J
Title: Characterization of junD: a new member of the jun proto-oncogene family.
Volume: 8
Issue: 5
Pages: 1433-9
Publication
First Author: Weitzman JB
Year: 2000
Journal: Mol Cell
Title: JunD protects cells from p53-dependent senescence and apoptosis.
Volume: 6
Issue: 5
Pages: 1109-19
Publication
First Author: Meixner A
Year: 2004
Journal: EMBO J
Title: JunD regulates lymphocyte proliferation and T helper cell cytokine expression.
Volume: 23
Issue: 6
Pages: 1325-35
Publication
First Author: Ricci R
Year: 2005
Journal: Genes Dev
Title: Distinct functions of junD in cardiac hypertrophy and heart failure.
Volume: 19
Issue: 2
Pages: 208-13
Publication
First Author: Pillebout E
Year: 2003
Journal: J Clin Invest
Title: JunD protects against chronic kidney disease by regulating paracrine mitogens.
Volume: 112
Issue: 6
Pages: 843-52
Publication
First Author: Ryder K
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: jun-D: a third member of the jun gene family.
Volume: 86
Issue: 5
Pages: 1500-3
Publication
First Author: Li L
Year: 1990
Journal: J Biol Chem
Title: Different members of the jun proto-oncogene family exhibit distinct patterns of expression in response to type beta transforming growth factor.
Volume: 265
Issue: 3
Pages: 1556-62
Publication
First Author: Pfarr CM
Year: 1994
Journal: Cell
Title: Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras.
Volume: 76
Issue: 4
Pages: 747-60
Publication
First Author: Costantino S
Year: 2019
Journal: Eur Heart J
Title: Obesity-induced activation of JunD promotes myocardial lipid accumulation and metabolic cardiomyopathy.
Volume: 40
Issue: 12
Pages: 997-1008
Publication
First Author: Hilfiker-Kleiner D
Year: 2005
Journal: Circulation
Title: Lack of JunD promotes pressure overload-induced apoptosis, hypertrophic growth, and angiogenesis in the heart.
Volume: 112
Issue: 10
Pages: 1470-7
Publication
First Author: Kameda T
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: JunD mutants with spontaneously acquired transforming potential have enhanced transactivating activity in combination with Fra-2.
Volume: 90
Issue: 20
Pages: 9369-73
Publication
First Author: Thépot D
Year: 2000
Journal: Development
Title: Targeted disruption of the murine junD gene results in multiple defects in male reproductive function.
Volume: 127
Issue: 1
Pages: 143-53
Publication
First Author: Paneni F
Year: 2013
Journal: Circulation
Title: Deletion of the activated protein-1 transcription factor JunD induces oxidative stress and accelerates age-related endothelial dysfunction.
Volume: 127
Issue: 11
Pages: 1229-40, e1-21
Publication
First Author: Kawamata A
Year: 2008
Journal: J Cell Biochem
Title: JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion.
Volume: 103
Issue: 4
Pages: 1037-45
Publication
First Author: Cook HT
Year: 2011
Journal: Am J Pathol
Title: AP-1 transcription factor JunD confers protection from accelerated nephrotoxic nephritis and control podocyte-specific Vegfa expression.
Volume: 179
Issue: 1
Pages: 134-40
Publication
First Author: Okazaki S
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Two proteins translated by alternative usage of initiation codons in mRNA encoding a JunD transcriptional regulator.
Volume: 250
Issue: 2
Pages: 347-53
Publication
First Author: Hipkaeo W
Year: 2004
Journal: J Histochem Cytochem
Title: Expression and localization of the transcription factor JunD in the duct system of mouse submandibular gland.
Volume: 52
Issue: 4
Pages: 479-90
Publication
First Author: Akhmedov A
Year: 2020
Journal: Thromb Haemost
Title: Cardiomyocyte-Specific JunD Overexpression Increases Infarct Size following Ischemia/Reperfusion Cardiac Injury by Downregulating Sirt3.
Volume: 120
Issue: 1
Pages: 168-180
Publication
First Author: Marden JJ
Year: 2008
Journal: J Biol Chem
Title: JunD protects the liver from ischemia/reperfusion injury by dampening AP-1 transcriptional activation.
Volume: 283
Issue: 11
Pages: 6687-95
Publication
First Author: Wang H
Year: 1996
Journal: Oncogene
Title: JunD phosphorylation, and expression of AP-1 DNA binding activity modulated by serum growth factors in quiescent murine 3T3T cells.
Volume: 13
Issue: 12
Pages: 2639-47
Publication
First Author: Alcivar AA
Year: 1991
Journal: Mol Reprod Dev
Title: junD mRNA expression differs from c-jun and junB mRNA expression during male germinal cell differentiation.
Volume: 30
Issue: 3
Pages: 187-93
Publication
First Author: Kashif M
Year: 2012
Journal: J Biol Chem
Title: Nuclear factor erythroid-derived 2 (Nfe2) regulates JunD DNA-binding activity via acetylation: a novel mechanism regulating trophoblast differentiation.
Volume: 287
Issue: 8
Pages: 5400-11
Publication
First Author: Hara M
Year: 2013
Journal: Mol Immunol
Title: Transcriptional regulation of the mouse CD11c promoter by AP-1 complex with JunD and Fra2 in dendritic cells.
Volume: 53
Issue: 3
Pages: 295-301
Author
Publication
First Author: Laurent G
Year: 2008
Journal: Cell Metab
Title: Oxidative stress contributes to aging by enhancing pancreatic angiogenesis and insulin signaling.
Volume: 7
Issue: 2
Pages: 113-24
Publication
First Author: Mandelzys A
Year: 1997
Journal: J Neurosci
Title: Absence of a persistently elevated 37 kDa fos-related antigen and AP-1-like DNA-binding activity in the brains of kainic acid-treated fosB null mice.
Volume: 17
Issue: 14
Pages: 5407-15
Publication
First Author: Marti A
Year: 1994
Journal: Oncogene
Title: Protein kinase A and AP-1 (c-Fos/JunD) are induced during apoptosis of mouse mammary epithelial cells.
Volume: 9
Issue: 4
Pages: 1213-23
Protein
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
Publication
First Author: Ebrahimkhani MR
Year: 2011
Journal: Nat Med
Title: Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.
Volume: 17
Issue: 12
Pages: 1668-73
Publication
First Author: Naito J
Year: 2005
Journal: J Biol Chem
Title: Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunD.
Volume: 280
Issue: 6
Pages: 4785-91
Publication
First Author: Hasenfuss SC
Year: 2014
Journal: Cell Metab
Title: Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers.
Volume: 19
Issue: 1
Pages: 84-95
Publication
First Author: Meixner A
Year: 2010
Journal: Cell Death Differ
Title: Jun and JunD-dependent functions in cell proliferation and stress response.
Volume: 17
Issue: 9
Pages: 1409-19
Publication
First Author: Agarwal SK
Year: 1999
Journal: Cell
Title: Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription.
Volume: 96
Issue: 1
Pages: 143-52
Publication
First Author: Ambivero CT
Year: 2012
Journal: Biochim Biophys Acta
Title: ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway.
Volume: 1823
Issue: 12
Pages: 2149-56
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Hafezi F
Year: 1999
Journal: Cell Death Differ
Title: Retinal photoreceptors are apoptosis-competent in the absence of JunD/AP-1.
Volume: 6
Issue: 10
Pages: 934-6
Publication  
First Author: Breau M
Year: 2019
Journal: JCI Insight
Title: The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice.
Volume: 4
Issue: 19
Publication
First Author: Williams JM
Year: 2000
Journal: Brain Res Mol Brain Res
Title: Sequential increase in Egr-1 and AP-1 DNA binding activity in the dentate gyrus following the induction of long-term potentiation.
Volume: 77
Issue: 2
Pages: 258-66
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1742828
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:1204468
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3288928
Stage: TS28
Assay Id: MGI:1204470
Age: postnatal week 6-8
Image: st96_175
Specimen Label: None
Detected: true
Specimen Num: 25