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Search results 1 to 100 out of 767 for Kat8

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Histone acetyltransferase KAT8 () has activity directed towards histones H3, H2A and H4 []and is the active component of the MSL and NSL complexes []. KAT8 autoacetylates itself on Lys-274 which is a requirement for binding to histone H4 []. In Drosophila melanogaster this protein is known as 'males-absent on the first protein' (MOF) [].The male-specific lethal (MSL) complex is a histone acetyltransferase with specificity for histone H4 'lysine-16' in chromatin. The complex consists of MOF, MSL1, MSL2, and MSL3 []. The complex was first identified in Drosophila.
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 458  
Fragment?: false
Publication
First Author: Neal KC
Year: 2000
Journal: Biochim Biophys Acta
Title: A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF.
Volume: 1490
Issue: 1-2
Pages: 170-4
Publication
First Author: Huang J
Year: 2012
Journal: Cell Res
Title: Structural insight into the regulation of MOF in the male-specific lethal complex and the non-specific lethal complex.
Volume: 22
Issue: 6
Pages: 1078-81
Publication
First Author: Yuan H
Year: 2012
Journal: EMBO J
Title: MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Volume: 31
Issue: 1
Pages: 58-70
Publication
First Author: Huai W
Year: 2019
Journal: J Exp Med
Title: KAT8 selectively inhibits antiviral immunity by acetylating IRF3.
Volume: 216
Issue: 4
Pages: 772-785
Publication
First Author: Raja SJ
Year: 2010
Journal: Mol Cell
Title: The nonspecific lethal complex is a transcriptional regulator in Drosophila.
Volume: 38
Issue: 6
Pages: 827-41
Publication
First Author: Smith ER
Year: 2005
Journal: Mol Cell Biol
Title: A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16.
Volume: 25
Issue: 21
Pages: 9175-88
Protein
Organism: Mus musculus
Length: 176  
Fragment?: true
Publication
First Author: Yin S
Year: 2017
Journal: Development
Title: Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating reactive oxygen species levels.
Volume: 144
Issue: 12
Pages: 2165-2174
Protein
Organism: Mus musculus
Length: 458  
Fragment?: false
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Pessoa Rodrigues C
Year: 2020
Journal: Sci Adv
Title: Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate.
Volume: 6
Issue: 21
Pages: eaaz4815
Publication
First Author: Karoutas A
Year: 2019
Journal: Nat Cell Biol
Title: The NSL complex maintains nuclear architecture stability via lamin A/C acetylation.
Volume: 21
Issue: 10
Pages: 1248-1260
Publication
First Author: Sheikh BN
Year: 2020
Journal: Nat Cell Biol
Title: Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature.
Volume: 22
Issue: 7
Pages: 828-841
Publication
First Author: Dmitriev RI
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Characterization of hampin/MSL1 as a node in the nuclear interactome.
Volume: 355
Issue: 4
Pages: 1051-7
Protein
Organism: Mus musculus
Length: 700  
Fragment?: false
Protein
Organism: Mus musculus
Length: 91  
Fragment?: true
Publication
First Author: Li L
Year: 2020
Journal: J Clin Invest
Title: Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability.
Volume: 130
Issue: 3
Pages: 1431-1445
Protein
Organism: Mus musculus
Length: 1036  
Fragment?: false
Protein
Organism: Mus musculus
Length: 991  
Fragment?: false
Protein
Organism: Mus musculus
Length: 647  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1099  
Fragment?: false
Protein
Organism: Mus musculus
Length: 486  
Fragment?: false
Protein
Organism: Mus musculus
Length: 452  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Chatterjee A
Year: 2016
Journal: Cell
Title: MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.
Volume: 167
Issue: 3
Pages: 722-738.e23
Publication
First Author: Thomas T
Year: 2008
Journal: Mol Cell Biol
Title: Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture.
Volume: 28
Issue: 16
Pages: 5093-105
Publication
First Author: Sheikh BN
Year: 2016
Journal: Oncogene
Title: MOF maintains transcriptional programs regulating cellular stress response.
Volume: 35
Issue: 21
Pages: 2698-710
Publication
First Author: Yang Y
Year: 2018
Journal: Cell Physiol Biochem
Title: Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis.
Volume: 47
Issue: 5
Pages: 2159-2169
Publication
First Author: Valerio DG
Year: 2017
Journal: Cancer Res
Title: Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.
Volume: 77
Issue: 7
Pages: 1753-1762
Publication
First Author: Kumar R
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice.
Volume: 108
Issue: 9
Pages: 3636-41
Publication
First Author: Gupta A
Year: 2013
Journal: Mutagenesis
Title: T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice.
Volume: 28
Issue: 3
Pages: 263-70
Publication
First Author: Qiao W
Year: 2014
Journal: Biochem Biophys Res Commun
Title: The histone acetyltransferase MOF overexpression blunts cardiac hypertrophy by targeting ROS in mice.
Volume: 448
Issue: 4
Pages: 379-84
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3713376
Age: embryonic day 12.5
Image: 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3713389
Age: embryonic day 12.5
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6115826
Age: embryonic day 14.5
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6115826
Age: embryonic day 14.5
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6115828
Age: embryonic day 10.5
Image: S1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6115828
Age: embryonic day 10.5
Image: S1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6115843
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6115843
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6115823
Age: embryonic day 14.5
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6115823
Age: embryonic day 14.5
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6115829
Age: embryonic day 10.5
Image: S1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6115829
Age: embryonic day 10.5
Image: S1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6115842
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6115785
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6115842
Age: embryonic day 18.5
Image: S1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624728
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:3713389
Age: postnatal day 0
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3713389
Age: postnatal day 7
Image: 5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3713389
Age: postnatal day 14
Image: 5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3713389
Age: postnatal day 21
Image: 5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3713389
Age: postnatal day 28
Image: 5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3713389
Age: postnatal day 35
Image: 5
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3713389
Age: postnatal day 42
Image: 5
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:3713368
Assay Type: Northern blot
Annotation Date: 2007-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3713376
Age: postnatal adult
Image: 1
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6511273
Assay Type: RT-PCR
Annotation Date: 2021-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6511276
Age: embryonic day 14.5
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:6511273
Assay Type: RT-PCR
Annotation Date: 2021-03-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6511276
Age: embryonic day 14.5
Specimen Num: 2
GXD Expression      
Probe: MGI:6511266
Assay Type: Western blot
Annotation Date: 2021-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6511279
Age: embryonic day 14.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6511266
Assay Type: Western blot
Annotation Date: 2021-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6511279
Age: embryonic day 14.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6511266
Assay Type: Western blot
Annotation Date: 2021-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6511279
Age: embryonic day 14.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6511266
Assay Type: Western blot
Annotation Date: 2021-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6511279
Age: embryonic day 14.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6511266
Assay Type: Western blot
Annotation Date: 2021-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6511279
Age: embryonic day 14.5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6511266
Assay Type: Western blot
Annotation Date: 2021-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6511279
Age: embryonic day 14.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6511266
Assay Type: Western blot
Annotation Date: 2021-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6511285
Age: embryonic day 14.5
Detected: true
Specimen Num: 1