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Search results 1 to 100 out of 472 for Kcne1

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Type Details Score
Gene
3753 | KCNE1
Type: gene
Organism: human
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Gene
474097 | KCNE1
Type: gene
Organism: chimpanzee
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Gene
528014 | KCNE1
Type: gene
Organism: cattle
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Gene
697229 | KCNE1
Type: gene
Organism: macaque, rhesus
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Gene
101748386 | KCNE1
Type: gene
Organism: chicken
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Gene
100486396 | kcne1
Type: gene
Organism: frog, western clawed
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Gene
25471 | Kcne1
Type: gene
Organism: rat
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Gene
487743 | KCNE1
Type: gene
Organism: dog, domestic
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Protein Domain
IPR005424 | KCNE1
Type: Family
Description: KCNE1 (Potassium voltage-gated channel subfamily E member 1, also known as Mink) subunits associate with KCNQ1 alpha subunits to form channels that are responsible for the IkS currents that determine the duration of the action potential in cardiac muscle []. Mutations in both of the genes encoding these subunits cause an inherited disorder that increases the risk of death from cardiac arrhythmia (long QT syndrome type 1) and Jervell and Lange-Nielsen syndrome, associated with congenital deafness [].Two types of beta subunit (KCNE and KCNAB) are presently known to associate with voltage-gated alpha subunits (Kv, KCNQ and eag-like). However, not all combinations of alpha and beta subunits are possible. The KCNE family of K+ channel subunits are membrane glycoproteins that possess a single transmembrane (TM) domain. They share no structural relationship with the alpha subunit proteins, which possess pore forming domains. The subunits appear to have a regulatory function, modulating the kinetics and voltage dependence of the alpha subunits of voltage-dependent K+ channels. KCNE subunits are formed from short polypeptides of ~130 amino acids, and are divided into five subfamilies: KCNE1 (MinK/IsK), KCNE2 (MiRP1), KCNE3 (MiRP2), KCNE4 (MiRP3) and KCNE1L (AMMECR2). Potassium channels are the most diverse group of the ion channel family [, ]. They are important in shaping the action potential, and in neuronal excitability and plasticity []. The potassium channel family is composed of several functionally distinct isoforms, which can be broadly separated into 2 groups []: the practically non-inactivating 'delayed' group and the rapidly inactivating 'transient' group.These are all highly similar proteins, with only small amino acid changes causing the diversity of the voltage-dependent gating mechanism, channel conductance and toxin binding properties. Each type of K+channel is activated by different signals and conditions depending on their type of regulation: some open in response to depolarisation of the plasma membrane; others in response to hyperpolarisation or an increase in intracellular calcium concentration; some can be regulated by binding of a transmitter, together with intracellular kinases; while others are regulated by GTP-binding proteins or other second messengers []. In eukaryotic cells, K+channels are involved in neural signalling and generation of the cardiac rhythm, act as effectors in signal transduction pathways involving G protein-coupled receptors (GPCRs) and may have a role in target cell lysis by cytotoxic T-lymphocytes []. In prokaryotic cells, they play a role in the maintenance of ionic homeostasis [].All K+channels discovered so far possess a core of alpha subunits, each comprising either one or two copies of a highly conserved pore loop domain (P-domain). The P-domain contains the sequence (T/SxxTxGxG), which has been termed the K+selectivity sequence. In families that contain one P-domain, four subunits assemble to form a selective pathway for K+across the membrane. However, it remains unclear how the 2 P-domain subunits assemble to form a selective pore. The functional diversity of these families can arise through homo- or hetero-associations of alpha subunits or association with auxiliary cytoplasmic beta subunits. K+channel subunits containing one pore domain can be assigned into one of two superfamilies: those that possess six transmembrane (TM) domains and those that possess only two TM domains. The six TM domain superfamily can be further subdivided into conserved gene families: the voltage-gated (Kv) channels; the KCNQ channels (originally known as KvLQT channels); the EAG-like K+channels; and three types of calcium (Ca)-activated K+channels (BK, IK and SK) []. The 2TM domain family comprises inward-rectifying K+channels. In addition, there are K+channel alpha-subunits that possess two P-domains. These are usually highly regulated K+selective leak channels.
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Protein Coding Gene
MGI:96673 | Kcne1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1624717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666277
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:648477
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:2666278
Age: embryonic day 10.5
Image: Kcne1 10.5dpc
Specimen Label: Kcne1 10.5dpc
Detected: true
Specimen Num: 1
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Publication
11003695 | J:64772
First Author: Letts VA
Year: 2000
Journal: Mamm Genome
Title: A new spontaneous mouse mutation in the Kcne1 gene.
Volume: 11
Issue: 10
Pages: 831-5
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Publication
11714488 | J:96707
First Author: Puchalski RB
Year: 2001
Journal: Physiol Behav
Title: NaCl consumption is attenuated in female KCNE1 null mutant mice.
Volume: 74
Issue: 3
Pages: 267-76
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GXD Expression
GXD Expression
     
Probe: MGI:1001000
Assay Type: RNA in situ
Annotation Date: 2003-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:2674659
Age: embryonic day 9.5
Specimen Label: Kcne1 9.5dpc
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2673406
Assay Type: RNA in situ
Annotation Date: 2003-09-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:2674723
Age: embryonic day 9.5
Specimen Label: Kcne1 9.5dpc
Detected: false
Specimen Num: 1
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Publication
33373586 | J:301484
First Author: Ávalos Prado P
Year: 2021
Journal: Cell
Title: KCNE1 is an auxiliary subunit of two distinct ion channel superfamilies.
Volume: 184
Issue: 2
Pages: 534-544.e11
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Publication
15123546 | J:105333
First Author: Millar ID
Year: 2004
Journal: Exp Physiol
Title: Volume regulation is defective in renal proximal tubule cells isolated from KCNE1 knockout mice.
Volume: 89
Issue: 2
Pages: 173-80
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Publication
11889581 | J:106204
First Author: Warth R
Year: 2002
Journal: Pflugers Arch
Title: The role of KCNQ1/KCNE1 K(+) channels in intestine and pancreas: lessons from the KCNE1 knockout mouse.
Volume: 443
Issue: 5-6
Pages: 822-8
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Publication
17095567 | J:140608
First Author: Thomas G
Year: 2007
Journal: J Physiol
Title: Mechanisms of ventricular arrhythmogenesis in mice following targeted disruption of KCNE1 modelling long QT syndrome 5.
Volume: 578
Issue: Pt 1
Pages: 99-114
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Publication
23504710 | J:199954
First Author: Sachse CC
Year: 2013
Journal: FASEB J
Title: BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels.
Volume: 27
Issue: 6
Pages: 2458-67
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Publication
10493825 | J:57928
First Author: Piccini M
Year: 1999
Journal: Genomics
Title: KCNE1-like gene is deleted in AMME contiguous gene syndrome: identification and characterization of the human and mouse homologs.
Volume: 60
Issue: 3
Pages: 251-7
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Publication
19219384 | -
First Author: McCrossan ZA
Year: 2009
Journal: J Membr Biol
Title: Regulation of the Kv2.1 potassium channel by MinK and MiRP1.
Volume: 228
Issue: 1
Pages: 1-14
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Protein
P23299
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: false
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Protein
Q545H6
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: false
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Publication
21576273 | J:189403
First Author: Neal AM
Year: 2011
Journal: J Physiol
Title: Renal defects in KCNE1 knockout mice are mimicked by chromanol 293B in vivo: identification of a KCNE1-regulated K+ conductance in the proximal tubule.
Volume: 589
Issue: Pt 14
Pages: 3595-609
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Publication
2451788 | J:9129
First Author: Tempel BL
Year: 1988
Journal: Nature
Title: Cloning of a probable potassium channel gene from mouse brain.
Volume: 332
Issue: 6167
Pages: 837-9
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Publication
1772658 | -
First Author: Perney TM
Year: 1991
Journal: Curr Opin Cell Biol
Title: The molecular biology of K+ channels.
Volume: 3
Issue: 4
Pages: 663-70
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Publication
1879548 | -
First Author: Luneau C
Year: 1991
Journal: FEBS Lett
Title: Shaw-like rat brain potassium channel cDNA's with divergent 3' ends.
Volume: 288
Issue: 1-2
Pages: 163-7
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Publication
1373731 | J:931
First Author: Attali B
Year: 1992
Journal: J Biol Chem
Title: Cloning, functional expression, and regulation of two K+ channels in human T lymphocytes.
Volume: 267
Issue: 12
Pages: 8650-7
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Publication
2448635 | -
First Author: Schwarz TL
Year: 1988
Journal: Nature
Title: Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila.
Volume: 331
Issue: 6152
Pages: 137-42
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Publication
2555158 | -
First Author: Stühmer W
Year: 1989
Journal: EMBO J
Title: Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain.
Volume: 8
Issue: 11
Pages: 3235-44
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Publication
11178249 | -
First Author: Miller C
Year: 2000
Journal: Genome Biol
Title: An overview of the potassium channel family.
Volume: 1
Issue: 4
Pages: REVIEWS0004
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Publication
11414731 | J:70160
First Author: Chabannes D
Year: 2001
Journal: Cell Immunol
Title: Mice disrupted for the KvLQT1 potassium channel regulator IsK gene accumulate mature T cells.
Volume: 209
Issue: 1
Pages: 1-9
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Publication
9790991 | J:50586
First Author: Charpentier F
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Adult KCNE1-knockout mice exhibit a mild cardiac cellular phenotype.
Volume: 251
Issue: 3
Pages: 806-10
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Publication
15947250 | J:110250
First Author: Temple J
Year: 2005
Journal: Circ Res
Title: Atrial fibrillation in KCNE1-null mice.
Volume: 97
Issue: 1
Pages: 62-9
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Publication
11438691 | J:77288
First Author: Arrighi I
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Altered potassium balance and aldosterone secretion in a mouse model of human congenital long QT syndrome.
Volume: 98
Issue: 15
Pages: 8792-7
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Publication
17627998 | J:140827
First Author: Eugène D
Year: 2007
Journal: J Physiol
Title: Developmental regulation of the membrane properties of central vestibular neurons by sensory vestibular information in the mouse.
Volume: 583
Issue: Pt 3
Pages: 923-43
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Publication
33514733 | J:302138
First Author: Wu X
Year: 2021
Journal: Nat Commun
Title: Gene therapy via canalostomy approach preserves auditory and vestibular functions in a mouse model of Jervell and Lange-Nielsen syndrome type 2.
Volume: 12
Issue: 1
Pages: 697
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Publication
11562398 | J:103378
First Author: Vallon V
Year: 2001
Journal: J Am Soc Nephrol
Title: Role of KCNE1-dependent K+ fluxes in mouse proximal tubule.
Volume: 12
Issue: 10
Pages: 2003-11
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Publication
21669976 | J:189400
First Author: Chandrasekhar KD
Year: 2011
Journal: J Physiol
Title: O-glycosylation of the cardiac I(Ks) complex.
Volume: 589
Issue: Pt 15
Pages: 3721-30
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Publication
14561835 | J:105415
First Author: Balasubramaniam R
Year: 2003
Journal: J Physiol
Title: Electrogram prolongation and nifedipine-suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1.
Volume: 552
Issue: Pt 2
Pages: 535-46
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Publication
11223304 | J:108905
First Author: Nicolas M
Year: 2001
Journal: Hear Res
Title: KCNQ1/KCNE1 potassium channels in mammalian vestibular dark cells.
Volume: 153
Issue: 1-2
Pages: 132-45
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Publication
11527966 | J:119156
First Author: Grahammer F
Year: 2001
Journal: J Biol Chem
Title: The small conductance K+ channel, KCNQ1: expression, function, and subunit composition in murine trachea.
Volume: 276
Issue: 45
Pages: 42268-75
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Publication
16901941 | J:121998
First Author: Knipper M
Year: 2006
Journal: J Physiol
Title: Deafness in LIMP2-deficient mice due to early loss of the potassium channel KCNQ1/KCNE1 in marginal cells of the stria vascularis.
Volume: 576
Issue: Pt 1
Pages: 73-86
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Publication
11557234 | J:74171
First Author: Franco D
Year: 2001
Journal: Cardiovasc Res
Title: Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development.
Volume: 52
Issue: 1
Pages: 65-75
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Publication
26454161 | J:251329
First Author: Agsten M
Year: 2015
Journal: J Mol Cell Cardiol
Title: BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs).
Volume: 89
Issue: Pt B
Pages: 335-48
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Protein Coding Gene
MGP_CAROLIEiJ_G0020975 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023056 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0023024 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0022994 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0023026 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0022787 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_96673 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0023473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0022306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0022756 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0022890 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0022864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0022960 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0022885 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0023491 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0022051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0022358 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0016680 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0021881 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
1655403 | J:11462
First Author: Honoré E
Year: 1991
Journal: EMBO J
Title: Cloning, expression, pharmacology and regulation of a delayed rectifier K+ channel in mouse heart.
Volume: 10
Issue: 10
Pages: 2805-11
•
•
•
•
•
Publication
1568475 | J:936
First Author: Lesage F
Year: 1992
Journal: FEBS Lett
Title: ISK, a slowly activating voltage-sensitive K+ channel. Characterization of multiple cDNAs and gene organization in the mouse.
Volume: 301
Issue: 2
Pages: 168-72
•
•
•
•
•
Publication
9933245 | J:53735
First Author: Kupershmidt S
Year: 1999
Journal: Circ Res
Title: Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system.
Volume: 84
Issue: 2
Pages: 146-52
•
•
•
•
•
Publication
12741710 | J:84141
First Author: Kondo RP
Year: 2003
Journal: J Cardiovasc Electrophysiol
Title: Development of the cardiac conduction system as delineated by minK-lacZ.
Volume: 14
Issue: 4
Pages: 383-91
•
•
•
•
•
Publication
16276415 | J:102500
First Author: Zhai P
Year: 2005
Journal: J Clin Invest
Title: Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.
Volume: 115
Issue: 11
Pages: 3045-56
•
•
•
•
•
Publication
8982171 | J:37461
First Author: Vetter DE
Year: 1996
Journal: Neuron
Title: Inner ear defects induced by null mutation of the isk gene.
Volume: 17
Issue: 6
Pages: 1251-64
•
•
•
•
•
Publication
9670922 | J:114194
First Author: Drici MD
Year: 1998
Journal: Circ Res
Title: Involvement of IsK-associated K+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome.
Volume: 83
Issue: 1
Pages: 95-102
•
•
•
•
•
Publication
15243133 | J:105528
First Author: Vidal PP
Year: 2004
Journal: J Physiol
Title: Postural and locomotor control in normal and vestibularly deficient mice.
Volume: 559
Issue: Pt 2
Pages: 625-38
•
•
•
•
•
Publication
10995738 | J:115346
First Author: Lock H
Year: 2000
Journal: J Biol Chem
Title: Contribution of the IsK (MinK) potassium channel subunit to regulatory volume decrease in murine tracheal epithelial cells.
Volume: 275
Issue: 45
Pages: 34849-52
•
•
•
•
•
Publication
7943198 | J:20434
First Author: Felipe A
Year: 1994
Journal: Am J Physiol
Title: Differential expression of Isk mRNAs in mouse tissue during development and pregnancy.
Volume: 267
Issue: 3 Pt 1
Pages: C700-5
•
•
•
•
•
Publication
9312006 | J:42968
First Author: Chouabe C
Year: 1997
Journal: EMBO J
Title: Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias.
Volume: 16
Issue: 17
Pages: 5472-9
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•
•
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GXD Expression
GXD Expression
     
Probe: MGI:2652570
Assay Type: Northern blot
Annotation Date: 2003-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2652577
Age: postnatal adult
Specimen Label: B
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2652570
Assay Type: Northern blot
Annotation Date: 2003-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2652577
Age: postnatal adult
Specimen Label: H
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2652570
Assay Type: Northern blot
Annotation Date: 2003-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2652577
Age: postnatal adult
Specimen Label: K
Detected: true
Specimen Num: 5
•
•
•
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•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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