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Search results 1 to 100 out of 322 for Kcnj11

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0.1s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:2346703
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825699
Age: embryonic day 14.5
Image: Additional file 4 Kcnj11
Specimen Label: Additional file 4 Kcnj11
Detected: true
Specimen Num: 1
Publication
First Author: Kane GC
Year: 2006
Journal: Hum Mol Genet
Title: KCNJ11 gene knockout of the Kir6.2 KATP channel causes maladaptive remodeling and heart failure in hypertension.
Volume: 15
Issue: 15
Pages: 2285-97
Publication
First Author: Hugill A
Year: 2010
Journal: Diabetologia
Title: A mutation in KCNJ11 causing human hyperinsulinism (Y12X) results in a glucose-intolerant phenotype in the mouse.
Volume: 53
Issue: 11
Pages: 2352-6
Publication
First Author: Yamada S
Year: 2006
Journal: J Physiol
Title: Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant.
Volume: 577
Issue: Pt 3
Pages: 1053-65
Publication
First Author: Girard CA
Year: 2009
Journal: J Clin Invest
Title: Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.
Volume: 119
Issue: 1
Pages: 80-90
Publication    
First Author: Karagiannis A
Year: 2021
Journal: Elife
Title: Lactate is an energy substrate for rodent cortical neurons and enhances their firing activity.
Volume: 10
Publication
First Author: Benninger RK
Year: 2011
Journal: Diabetologia
Title: Defects in beta cell Ca²+ signalling, glucose metabolism and insulin secretion in a murine model of K(ATP) channel-induced neonatal diabetes mellitus.
Volume: 54
Issue: 5
Pages: 1087-97
Publication
First Author: Emfinger CH
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Contribution of systemic inflammation to permanence of KATP-induced neonatal diabetes in mice.
Volume: 315
Issue: 6
Pages: E1121-E1132
Publication
First Author: Clark R
Year: 2012
Journal: Diabetologia
Title: Mice expressing a human K(ATP) channel mutation have altered channel ATP sensitivity but no cardiac abnormalities.
Volume: 55
Issue: 4
Pages: 1195-204
Publication    
First Author: Ramu Y
Year: 2022
Journal: Elife
Title: Blocking Kir6.2 channels with SpTx1 potentiates glucose-stimulated insulin secretion from murine pancreatic β cells and lowers blood glucose in diabetic mice.
Volume: 11
Publication
First Author: Shyr ZA
Year: 2019
Journal: Sci Rep
Title: The role of membrane excitability in pancreatic β-cell glucotoxicity.
Volume: 9
Issue: 1
Pages: 6952
Publication
First Author: Tong X
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits.
Volume: 291
Issue: 2
Pages: H543-51
Publication
First Author: Tovar S
Year: 2013
Journal: Cell Metab
Title: K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis.
Volume: 18
Issue: 3
Pages: 445-55
Publication
First Author: Kong D
Year: 2010
Journal: Cell Metab
Title: Glucose stimulation of hypothalamic MCH neurons involves K(ATP) channels, is modulated by UCP2, and regulates peripheral glucose homeostasis.
Volume: 12
Issue: 5
Pages: 545-52
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Sakura H
Year: 1995
Journal: FEBS Lett
Title: Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle.
Volume: 377
Issue: 3
Pages: 338-44
Publication
First Author: Remedi MS
Year: 2004
Journal: Diabetes
Title: Diet-induced glucose intolerance in mice with decreased beta-cell ATP-sensitive K+ channels.
Volume: 53
Issue: 12
Pages: 3159-67
Publication
First Author: Sachse G
Year: 2021
Journal: Diabetes
Title: The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion.
Volume: 70
Issue: 5
Pages: 1145-1156
Publication
First Author: MacDonald PE
Year: 2007
Journal: PLoS Biol
Title: A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.
Volume: 5
Issue: 6
Pages: e143
Publication
First Author: Miki T
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.
Volume: 95
Issue: 18
Pages: 10402-6
Publication
First Author: Scott K
Year: 2016
Journal: Am J Physiol Cell Physiol
Title: KATP channel deficiency in mouse FDB causes an impairment of energy metabolism during fatigue.
Volume: 311
Issue: 4
Pages: C559-C571
Publication
First Author: Shi XR
Year: 2008
Journal: Neurosci Lett
Title: Kir6.2 knockout alters neurotransmitter release in mouse striatum: an in vivo microdialysis study.
Volume: 439
Issue: 3
Pages: 230-4
Publication
First Author: Gao Z
Year: 2016
Journal: PLoS One
Title: Loss of ATP-Sensitive Potassium Channel Surface Expression in Heart Failure Underlies Dysregulation of Action Potential Duration and Myocardial Vulnerability to Injury.
Volume: 11
Issue: 3
Pages: e0151337
Publication
First Author: Winarto A
Year: 2001
Journal: Arch Histol Cytol
Title: Morphological changes in pancreatic islets of KATP channel-deficient mice: the involvement of KATP channels in the survival of insulin cells and the maintenance of islet architecture.
Volume: 64
Issue: 1
Pages: 59-67
Publication
First Author: Suzuki M
Year: 2001
Journal: Circ Res
Title: Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice.
Volume: 88
Issue: 6
Pages: 570-7
Publication
First Author: Yamada K
Year: 2001
Journal: Science
Title: Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure.
Volume: 292
Issue: 5521
Pages: 1543-6
Publication
First Author: Chatterjee S
Year: 2006
Journal: Microcirculation
Title: KATP channels are an important component of the shear-sensing mechanism in the pulmonary microvasculature.
Volume: 13
Issue: 8
Pages: 633-44
Publication
First Author: Arrell DK
Year: 2009
Journal: J Proteome Res
Title: ATP-sensitive K+ channel knockout induces cardiac proteome remodeling predictive of heart disease susceptibility.
Volume: 8
Issue: 10
Pages: 4823-34
Publication
First Author: Zhou Y
Year: 2012
Journal: Neurosci Res
Title: Enhanced MK-801-induced locomotion in Kir6.2 knockout mice.
Volume: 74
Issue: 3-4
Pages: 195-9
Publication
First Author: Suzuki M
Year: 2002
Journal: J Clin Invest
Title: Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice.
Volume: 109
Issue: 4
Pages: 509-16
Publication
First Author: Miki T
Year: 2005
Journal: Diabetes
Title: Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility.
Volume: 54
Issue: 4
Pages: 1056-63
Publication
First Author: Youssef N
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: Hearts lacking plasma membrane KATP channels display changes in basal aerobic metabolic substrate preference and AMPK activity.
Volume: 313
Issue: 3
Pages: H469-H478
Publication
First Author: Betourne A
Year: 2009
Journal: Neuropharmacology
Title: Involvement of hippocampal CA3 K(ATP) channels in contextual memory.
Volume: 56
Issue: 3
Pages: 615-25
Publication
First Author: Ravier MA
Year: 2009
Journal: Endocrinology
Title: Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.
Volume: 150
Issue: 1
Pages: 33-45
Publication
First Author: Gumina RJ
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart.
Volume: 292
Issue: 4
Pages: H1706-13
Publication
First Author: Seino S
Year: 2000
Journal: Diabetes
Title: Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice.
Volume: 49
Issue: 3
Pages: 311-8
Publication
First Author: Kanezaki Y
Year: 2004
Journal: Endocr J
Title: K(ATP) channel knockout mice crossbred with transgenic mice expressing a dominant-negative form of human insulin receptor have glucose intolerance but not diabetes.
Volume: 51
Issue: 2
Pages: 133-44
Publication
First Author: Jilkina O
Year: 2006
Journal: J Mol Cell Cardiol
Title: K+ transport and energetics in Kir6.2(-/-) mouse hearts assessed by 87Rb and 31P magnetic resonance and optical spectroscopy.
Volume: 41
Issue: 5
Pages: 893-901
Publication
First Author: Schiemann J
Year: 2012
Journal: Nat Neurosci
Title: K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration.
Volume: 15
Issue: 9
Pages: 1272-80
Publication  
First Author: Kane GC
Year: 2004
Journal: Diabetes
Title: ATP-sensitive K+ channel knockout compromises the metabolic benefit of exercise training, resulting in cardiac deficits.
Volume: 53 Suppl 3
Pages: S169-75
Publication
First Author: Gumina RJ
Year: 2003
Journal: Am J Physiol Heart Circ Physiol
Title: Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics.
Volume: 284
Issue: 6
Pages: H2106-13
Publication
First Author: Saito T
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Role of ATP-sensitive K+ channels in electrophysiological alterations during myocardial ischemia: a study using Kir6.2-null mice.
Volume: 288
Issue: 1
Pages: H352-7
Publication
First Author: Cifelli C
Year: 2007
Journal: J Physiol
Title: KATP channel deficiency in mouse flexor digitorum brevis causes fibre damage and impairs Ca2+ release and force development during fatigue in vitro.
Volume: 582
Issue: Pt 2
Pages: 843-57
Publication  
First Author: Zhang Q
Year: 2018
Journal: Mol Cell Neurosci
Title: Deletion of Kir6.2/SUR1 potassium channels rescues diminishing of DA neurons via decreasing iron accumulation in PD.
Volume: 92
Pages: 164-176
Publication
First Author: Deacon RM
Year: 2006
Journal: Physiol Behav
Title: Behavioral phenotyping of mice lacking the K ATP channel subunit Kir6.2.
Volume: 87
Issue: 4
Pages: 723-33
Publication
First Author: Sun HS
Year: 2006
Journal: J Neurophysiol
Title: Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K+ channels.
Volume: 95
Issue: 4
Pages: 2590-601
Publication
First Author: Alekseev AE
Year: 2010
Journal: Cell Metab
Title: Sarcolemmal ATP-sensitive K(+) channels control energy expenditure determining body weight.
Volume: 11
Issue: 1
Pages: 58-69
Publication
First Author: Saegusa N
Year: 2005
Journal: Cardiovasc Res
Title: Kir6.2-deficient mice are susceptible to stimulated ANP secretion: K(ATP) channel acts as a negative feedback mechanism?
Volume: 67
Issue: 1
Pages: 60-8
Publication
First Author: Miki T
Year: 2001
Journal: Nat Neurosci
Title: ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.
Volume: 4
Issue: 5
Pages: 507-12
Publication  
First Author: Miki T
Year: 2001
Journal: Diabetes
Title: Roles of ATP-sensitive K+ channels in cell survival and differentiation in the endocrine pancreas.
Volume: 50 Suppl 1
Pages: S48-51
Publication
First Author: Chowdhury UR
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure in vivo.
Volume: 54
Issue: 7
Pages: 4892-9
Publication
First Author: Fukuzaki K
Year: 2008
Journal: J Physiol
Title: Role of sarcolemmal ATP-sensitive K+ channels in the regulation of sinoatrial node automaticity: an evaluation using Kir6.2-deficient mice.
Volume: 586
Issue: 11
Pages: 2767-78
Publication
First Author: Reyes S
Year: 2007
Journal: Mol Psychiatry
Title: KATP channels confer survival advantage in cocaine overdose.
Volume: 12
Issue: 12
Pages: 1060-1
Publication
First Author: Wojtovich AP
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: Kir6.2 is not the mitochondrial KATP channel but is required for cardioprotection by ischemic preconditioning.
Volume: 304
Issue: 11
Pages: H1439-45
Publication
First Author: Fujimoto W
Year: 2009
Journal: Diabetologia
Title: Niflumic acid-sensitive ion channels play an important role in the induction of glucose-stimulated insulin secretion by cyclic AMP in mice.
Volume: 52
Issue: 5
Pages: 863-72
Publication
First Author: Seino Y
Year: 2013
Journal: J Endocrinol
Title: Cephalic phase insulin secretion is KATP channel independent.
Volume: 218
Issue: 1
Pages: 25-33
Publication
First Author: Zingman LV
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Kir6.2 is required for adaptation to stress.
Volume: 99
Issue: 20
Pages: 13278-83
Publication  
First Author: Liu XK
Year: 2004
Journal: Diabetes
Title: Genetic disruption of Kir6.2, the pore-forming subunit of ATP-sensitive K+ channel, predisposes to catecholamine-induced ventricular dysrhythmia.
Volume: 53 Suppl 3
Pages: S165-8
Publication
First Author: Miki T
Year: 2002
Journal: Am J Physiol Endocrinol Metab
Title: ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue.
Volume: 283
Issue: 6
Pages: E1178-84
Publication
First Author: Arrell DK
Year: 2022
Journal: Sci Rep
Title: KATP channel dependent heart multiome atlas.
Volume: 12
Issue: 1
Pages: 7314
Publication
First Author: Sun HS
Year: 2007
Journal: Neuroscience
Title: Kir6.2-containing ATP-sensitive potassium channels protect cortical neurons from ischemic/anoxic injury in vitro and in vivo.
Volume: 144
Issue: 4
Pages: 1509-15
Publication  
First Author: Saito A
Year: 2018
Journal: Physiol Behav
Title: Possible involvement of monoamine neurons in the emotional abnormality in Kir6.2-deficient mice.
Volume: 188
Pages: 251-261
Publication
First Author: Mankouri J
Year: 2006
Journal: EMBO J
Title: Kir6.2 mutations causing neonatal diabetes prevent endocytosis of ATP-sensitive potassium channels.
Volume: 25
Issue: 17
Pages: 4142-51
Publication
First Author: Lorenz E
Year: 1998
Journal: Mol Cell Biol
Title: Evidence for direct physical association between a K+ channel (Kir6.2) and an ATP-binding cassette protein (SUR1) which affects cellular distribution and kinetic behavior of an ATP-sensitive K+ channel.
Volume: 18
Issue: 3
Pages: 1652-9
Publication
First Author: Inagaki N
Year: 1996
Journal: Neuron
Title: A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels.
Volume: 16
Issue: 5
Pages: 1011-7
Publication
First Author: John SA
Year: 2003
Journal: J Physiol
Title: Molecular mechanism for ATP-dependent closure of the K+ channel Kir6.2.
Volume: 552
Issue: Pt 1
Pages: 23-34
Publication
First Author: Xu H
Year: 2001
Journal: J Biol Chem
Title: Direct activation of cloned K(atp) channels by intracellular acidosis.
Volume: 276
Issue: 16
Pages: 12898-902
Publication
First Author: Suzuki M
Year: 1997
Journal: Diabetes
Title: Localization of the ATP-sensitive K+ channel subunit Kir6.2 in mouse pancreas.
Volume: 46
Issue: 9
Pages: 1440-4
Publication  
First Author: Seino S
Year: 1999
Journal: Annu Rev Physiol
Title: ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies.
Volume: 61
Pages: 337-62
Publication
First Author: Miki T
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Abnormalities of pancreatic islets by targeted expression of a dominant-negative KATP channel.
Volume: 94
Issue: 22
Pages: 11969-73
Publication
First Author: Lin YW
Year: 2003
Journal: J Gen Physiol
Title: Stabilization of the activity of ATP-sensitive potassium channels by ion pairs formed between adjacent Kir6.2 subunits.
Volume: 122
Issue: 2
Pages: 225-37