|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 92 out of 92 for Kcnk4

0.027s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
617184 | KCNK4
Type: gene
Organism: cattle
•
•
•
•
•
Gene
423536 | KCNK4
Type: gene
Organism: chicken
•
•
•
•
•
Gene
100488063 | kcnk4
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
50801 | KCNK4
Type: gene
Organism: human
•
•
•
•
•
Gene
116489 | Kcnk4
Type: gene
Organism: rat
•
•
•
•
•
Gene
612120 | KCNK4
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
743334 | KCNK4
Type: gene
Organism: chimpanzee
•
•
•
•
•
Protein Coding Gene
MGI:1298234 | Kcnk4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0022618 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0024772 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0024738 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0024711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0024738 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0024506 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_1298234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0025184 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0023977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0024478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0024605 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0024571 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0024691 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0024600 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0025232 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0023723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0024040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0014112 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0023529 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
9628867 | J:48292
First Author: Fink M
Year: 1998
Journal: EMBO J
Title: A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids.
Volume: 17
Issue: 12
Pages: 3297-308
•
•
•
•
•
Publication
31674909 | J:283386
   
First Author: Brohawn SG
Year: 2019
Journal: Elife
Title: The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier.
Volume: 8
•
•
•
•
•
Publication
23285272 | J:195740
First Author: Laigle C
Year: 2012
Journal: PLoS One
Title: Deletion of TRAAK potassium channel affects brain metabolism and protects against ischemia.
Volume: 7
Issue: 12
Pages: e53266
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3707786
Assay Type: RT-PCR
Annotation Date: 2007-05-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:3709074
Age: embryonic day 17.5
Specimen Label: Fetus
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3707786
Assay Type: RT-PCR
Annotation Date: 2007-05-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3709074
Age: postnatal day 1
Specimen Label: Neonate
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3707786
Assay Type: RT-PCR
Annotation Date: 2007-05-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3709074
Age: postnatal adult
Specimen Label: Adult
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433544
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5433717
Age: embryonic day 1.0
Specimen Label: 2-Cell
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433544
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:5433717
Age: embryonic day 2.5
Specimen Label: 8-Cell
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433544
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5433717
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433544
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5433717
Age: embryonic day 3.5
Specimen Label: Blastocyst
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433545
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5433722
Age: embryonic day 1.0
Specimen Label: 2-Cell
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433545
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:5433722
Age: embryonic day 2.5
Specimen Label: 8-Cell
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433545
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5433722
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433545
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5433722
Age: embryonic day 3.5
Specimen Label: Blastocyst
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433544
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5433717
Age: postnatal adult
Specimen Label: OocyteMII
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5433545
Assay Type: RT-PCR
Annotation Date: 2012-09-13
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5433722
Age: postnatal adult
Specimen Label: OocyteMII
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6457043
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:6457077
Age: embryonic day 15.5
Specimen Label: Ovary Fetal
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6457043
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:6457077
Age: postnatal adult
Specimen Label: Ovary Adult
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6457043
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:6457077
Age: embryonic day 15.5
Specimen Label: Testis Fetal
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6457043
Assay Type: RT-PCR
Annotation Date: 2020-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6457077
Age: postnatal adult
Specimen Label: Testis Adult
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6457054
Assay Type: RNA in situ
Annotation Date: 2020-09-24
Strength: Present
Sex: Male
Emaps: EMAPS:3148628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6457090
Age: postnatal adult
Note: Expression in spermatids, suggesting a late spermiogenesis function.
Specimen Label: 3 MLZ-622
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5433702
Assay Type: Immunohistochemistry
Annotation Date: 2012-09-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:5433734
Age: embryonic day 3.5
Note: Expressed in the plasma membrane.
Specimen Label: 2C Blastocyst
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5433702
Assay Type: Immunohistochemistry
Annotation Date: 2012-09-13
Strength: Strong
Sex: Female
Emaps: EMAPS:3575528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5433734
Age: postnatal adult
Note: Expressed in the plasma membrane.
Specimen Label: 2C OocyteMII
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5433702
Assay Type: Immunohistochemistry
Annotation Date: 2012-09-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:5433734
Age: embryonic day 1.0
Note: Expressed in the plasma membrane.
Specimen Label: 2C 2-Cell
Detected: true
Specimen Num: 2
•
•
•
•
•
Publication
19279663 | J:148714
First Author: Noël J
Year: 2009
Journal: EMBO J
Title: The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception.
Volume: 28
Issue: 9
Pages: 1308-18
•
•
•
•
•
Publication
15175651 | J:91531
First Author: Heurteaux C
Year: 2004
Journal: EMBO J
Title: TREK-1, a K+ channel involved in neuroprotection and general anesthesia.
Volume: 23
Issue: 13
Pages: 2684-95
•
•
•
•
•
Publication
25239074 | J:267798
First Author: Pereira V
Year: 2014
Journal: Pain
Title: Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception.
Volume: 155
Issue: 12
Pages: 2534-44
•
•
•
•
•
Publication
22973213 | J:241835
 
First Author: Mirkovic K
Year: 2012
Journal: Front Behav Neurosci
Title: Behavioral characterization of mice lacking Trek channels.
Volume: 6
Pages: 60
•
•
•
•
•
Publication
11167025 | J:67344
First Author: Bockenhauer D
Year: 2000
Journal: Gene
Title: Genomic organization and chromosomal localization of the murine 2 P domain potassium channel gene Kcnk8: conservation of gene structure in 2 P domain potassium channels.
Volume: 261
Issue: 2
Pages: 365-72
•
•
•
•
•
Publication
27035965 | J:232118
First Author: Blin S
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties.
Volume: 113
Issue: 15
Pages: 4200-5
•
•
•
•
•
Publication
31236347 | J:283633
First Author: Zhang XT
Year: 2019
Journal: Int J Ophthalmol
Title: Elevated expression of TREK-TRAAK K2P channels in the retina of adult rd1 mice.
Volume: 12
Issue: 6
Pages: 924-929
•
•
•
•
•
Publication
30144319 | J:266992
First Author: Gómez-Gonzalo M
Year: 2018
Journal: Glia
Title: Insights into the release mechanism of astrocytic glutamate evoking in neurons NMDA receptor-mediated slow depolarizing inward currents.
Volume: 66
Issue: 10
Pages: 2188-2199
•
•
•
•
•
Publication
19244527 | J:145944
First Author: Guyon A
Year: 2009
Journal: J Neurosci
Title: Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels.
Volume: 29
Issue: 8
Pages: 2528-33
•
•
•
•
•
Publication
34852225 | J:324668
First Author: Glogowska E
Year: 2021
Journal: Cell Rep
Title: Piezo1 and Piezo2 foster mechanical gating of K2P channels.
Volume: 37
Issue: 9
Pages: 110070
•
•
•
•
•
Publication
22419831 | J:185214
First Author: Hur CG
Year: 2012
Journal: Reproduction
Title: K(+) efflux through two-pore domain K(+) channels is required for mouse embryonic development.
Volume: 143
Issue: 5
Pages: 625-36
•
•
•
•
•
Publication
23473320 | J:197938
First Author: Hao J
Year: 2013
Journal: Neuron
Title: Kv1.1 channels act as mechanical brake in the senses of touch and pain.
Volume: 77
Issue: 5
Pages: 899-914
•
•
•
•
•
Publication
22832196 | J:323538
First Author: Peyronnet R
Year: 2012
Journal: Cell Rep
Title: Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels.
Volume: 1
Issue: 3
Pages: 241-50
•
•
•
•
•
Publication
28839101 | J:251470
First Author: Schwingshackl A
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Hyperoxia treatment of TREK-1/TREK-2/TRAAK-deficient mice is associated with a reduction in surfactant proteins.
Volume: 313
Issue: 6
Pages: L1030-L1046
•
•
•
•
•
Publication
20339383 | J:187568
First Author: Kogo H
Year: 2010
Journal: J Hum Genet
Title: Screening of genes involved in chromosome segregation during meiosis I: toward the identification of genes responsible for infertility in humans.
Volume: 55
Issue: 5
Pages: 293-9
•
•
•
•
•
Publication
10843805 | J:62530
First Author: Tarantino LM
Year: 2000
Journal: Genomics
Title: A high-resolution radiation hybrid map of the proximal portion of mouse chromosome 5.
Volume: 66
Issue: 1
Pages: 55-64
•
•
•
•
•
Publication
16985003 | J:119550
First Author: Harrell MD
Year: 2007
Journal: Physiol Genomics
Title: Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.
Volume: 28
Issue: 3
Pages: 273-83
•
•
•
•
•
Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
28356343 | J:247843
First Author: King EC
Year: 2017
Journal: FASEB J
Title: Targeted deletion of Kcne3 impairs skeletal muscle function in mice.
Volume: 31
Issue: 7
Pages: 2937-2947
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom