Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
guinea pig |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
TASK is a member of the TWIK-related (two P-domain) K+channel familyidentified in human tissues []. It is widely distributed, being particularly abundant in the pancreas and placenta, but it is also found inthe brain, heart, lung and kidney. Its amino acid identity to TWIK-1 and TREK-1 is rather low, being about 25-28%. However, it is thought to share the same topology of four TM segments, with two P-domains. TASK is very sensitive to variations in extracellular pH in the physiological range, changing from fully-open to closed in approximately 0.5 pH units around pH 7.4. Thus, it may well be a biological sensor of external pH variations.Potassium channel subfamily K member 9 (KCNK9, also known as TASK3) is a pH-dependent, voltage-insensitive, background potassium channel protein [, ]. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
402
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Duprat F |
Year: |
1997 |
Journal: |
EMBO J |
Title: |
TASK, a human background K+ channel to sense external pH variations near physiological pH. |
Volume: |
16 |
Issue: |
17 |
Pages: |
5464-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chapman CG |
Year: |
2000 |
Journal: |
Brain Res Mol Brain Res |
Title: |
Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel. |
Volume: |
82 |
Issue: |
1-2 |
Pages: |
74-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vega-Saenz de Miera E |
Year: |
2001 |
Journal: |
J Neurophysiol |
Title: |
KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1. |
Volume: |
86 |
Issue: |
1 |
Pages: |
130-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cooper A |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
Inhibition of histone deacetylation rescues phenotype in a mouse model of Birk-Barel intellectual disability syndrome. |
Volume: |
11 |
Issue: |
1 |
Pages: |
480 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bando Y |
Year: |
2014 |
Journal: |
Cereb Cortex |
Title: |
Dysfunction of KCNK potassium channels impairs neuronal migration in the developing mouse cerebral cortex. |
Volume: |
24 |
Issue: |
4 |
Pages: |
1017-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hur CG |
Year: |
2012 |
Journal: |
Reproduction |
Title: |
K(+) efflux through two-pore domain K(+) channels is required for mouse embryonic development. |
Volume: |
143 |
Issue: |
5 |
Pages: |
625-36 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Penton D |
Year: |
2012 |
Journal: |
Endocrinology |
Title: |
Task3 potassium channel gene invalidation causes low renin and salt-sensitive arterial hypertension. |
Volume: |
153 |
Issue: |
10 |
Pages: |
4740-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gotter AL |
Year: |
2011 |
Journal: |
Brain Res |
Title: |
TASK-3 as a potential antidepressant target. |
Volume: |
1416 |
|
Pages: |
69-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brickley SG |
Year: |
2007 |
Journal: |
J Neurosci |
Title: |
TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons. |
Volume: |
27 |
Issue: |
35 |
Pages: |
9329-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Linden AM |
Year: |
2007 |
Journal: |
J Pharmacol Exp Ther |
Title: |
TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics. |
Volume: |
323 |
Issue: |
3 |
Pages: |
924-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guagliardo NA |
Year: |
2012 |
Journal: |
Hypertension |
Title: |
TASK-3 channel deletion in mice recapitulates low-renin essential hypertension. |
Volume: |
59 |
Issue: |
5 |
Pages: |
999-1005 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liao P |
Year: |
2019 |
Journal: |
Sci Transl Med |
Title: |
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models. |
Volume: |
11 |
Issue: |
519 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wen X |
Year: |
2022 |
Journal: |
Sci Adv |
Title: |
Tandem pore domain acid-sensitive K channel 3 (TASK-3) regulates visual sensitivity in healthy and aging retina. |
Volume: |
8 |
Issue: |
36 |
Pages: |
eabn8785 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clarke CE |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function. |
Volume: |
283 |
Issue: |
25 |
Pages: |
16985-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshida K |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Leak potassium channels regulate sleep duration. |
Volume: |
115 |
Issue: |
40 |
Pages: |
E9459-E9468 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maltby CJ |
Year: |
2020 |
Journal: |
Nucleic Acids Res |
Title: |
A 5' UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation. |
Volume: |
48 |
Issue: |
17 |
Pages: |
9822-9839 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433551 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360422 |
|
Stage: |
TS02 |
Assay Id: |
MGI:5433719 |
Age: |
embryonic day 1.0 |
|
|
Specimen Label: |
2-Cell |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433551 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360443 |
|
Stage: |
TS03 |
Assay Id: |
MGI:5433719 |
Age: |
embryonic day 2.5 |
|
|
Specimen Label: |
8-Cell |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433551 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360453 |
|
Stage: |
TS03 |
Assay Id: |
MGI:5433719 |
Age: |
embryonic day 3.0 |
|
|
Specimen Label: |
Morula |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433551 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360464 |
|
Stage: |
TS04 |
Assay Id: |
MGI:5433719 |
Age: |
embryonic day 3.5 |
|
|
Specimen Label: |
Blastocyst |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433553 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360422 |
|
Stage: |
TS02 |
Assay Id: |
MGI:5433724 |
Age: |
embryonic day 1.0 |
|
|
Specimen Label: |
2-Cell |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433553 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360443 |
|
Stage: |
TS03 |
Assay Id: |
MGI:5433724 |
Age: |
embryonic day 2.5 |
|
|
Specimen Label: |
8-Cell |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433553 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360453 |
|
Stage: |
TS03 |
Assay Id: |
MGI:5433724 |
Age: |
embryonic day 3.0 |
|
|
Specimen Label: |
Morula |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433553 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360464 |
|
Stage: |
TS04 |
Assay Id: |
MGI:5433724 |
Age: |
embryonic day 3.5 |
|
|
Specimen Label: |
Blastocyst |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433551 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3575528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5433719 |
Age: |
postnatal adult |
|
|
Specimen Label: |
OocyteMII |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433553 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3575528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5433724 |
Age: |
postnatal adult |
|
|
Specimen Label: |
OocyteMII |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270423 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
1B E15 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270425 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
1B E17 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3526027 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
1B P0 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3526027 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 3 |
|
|
Specimen Label: |
1B P3 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525727 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
1B P0 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525727 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 3 |
|
|
Specimen Label: |
1B P3 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271123 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
1B E15 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271127 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 3 |
|
Note: |
Increased expression after birth. |
Specimen Label: |
1B P3 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271127 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 0 |
|
Note: |
Increased expression after birth. |
Specimen Label: |
1B P0 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271125 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
1B E17 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271223 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
1B E15 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271225 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
1B E17 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525827 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
1B P0 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525827 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 3 |
|
|
Specimen Label: |
1B P3 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271325 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
1B E17 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525927 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
1B P0 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525927 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 3 |
|
|
Specimen Label: |
1B P3 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433560 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:360354 |
Pattern: |
Not Specified |
Stage: |
TS04 |
Assay Id: |
MGI:5433736 |
Age: |
embryonic day 3.5 |
|
Note: |
Expressed in the plasma membrane. |
Specimen Label: |
2C Blastocyst |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754623 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
1B E15 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
1B E15 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754725 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:6196589 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
1B E17 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525527 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
1B P0 |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525527 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 3 |
|
|
Specimen Label: |
1B P3 |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433560 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-09-13 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3575528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5433736 |
Age: |
postnatal adult |
|
Note: |
Expressed in the plasma membrane. |
Specimen Label: |
2C OocyteMII |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525627 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
1B P0 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6196576 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-09-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525627 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:6196589 |
Age: |
postnatal day 3 |
|
|
Specimen Label: |
1B P3 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5433560 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-09-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:160362 |
Pattern: |
Not Specified |
Stage: |
TS02 |
Assay Id: |
MGI:5433736 |
Age: |
embryonic day 1.0 |
|
Note: |
Expressed in the plasma membrane. |
Specimen Label: |
2C 2-Cell |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dadi PK |
Year: |
2014 |
Journal: |
Endocrinology |
Title: |
Pancreatic β-cell-specific ablation of TASK-1 channels augments glucose-stimulated calcium entry and insulin secretion, improving glucose tolerance. |
Volume: |
155 |
Issue: |
10 |
Pages: |
3757-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mulkey DK |
Year: |
2007 |
Journal: |
J Neurosci |
Title: |
TASK channels determine pH sensitivity in select respiratory neurons but do not contribute to central respiratory chemosensitivity. |
Volume: |
27 |
Issue: |
51 |
Pages: |
14049-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trapp S |
Year: |
2008 |
Journal: |
J Neurosci |
Title: |
A role for TASK-1 (KCNK3) channels in the chemosensory control of breathing. |
Volume: |
28 |
Issue: |
35 |
Pages: |
8844-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Turner PJ |
Year: |
2013 |
Journal: |
J Physiol |
Title: |
Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 channels in mouse carotid body type-1 cells. |
Volume: |
591 |
Issue: |
23 |
Pages: |
5977-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pang DS |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
An unexpected role for TASK-3 potassium channels in network oscillations with implications for sleep mechanisms and anesthetic action. |
Volume: |
106 |
Issue: |
41 |
Pages: |
17546-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Buehler PK |
Year: |
2017 |
Journal: |
Respir Physiol Neurobiol |
Title: |
Abnormal respiration under hyperoxia in TASK-1/3 potassium channel double knockout mice. |
Volume: |
244 |
|
Pages: |
17-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muhammad S |
Year: |
2010 |
Journal: |
Neuroscience |
Title: |
Expression of the kcnk3 potassium channel gene lessens the injury from cerebral ischemia, most likely by a general influence on blood pressure. |
Volume: |
167 |
Issue: |
3 |
Pages: |
758-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Inoue M |
Year: |
2019 |
Journal: |
FASEB J |
Title: |
Lack of p11 expression facilitates acidity-sensing function of TASK1 channels in mouse adrenal medullary cells. |
Volume: |
33 |
Issue: |
1 |
Pages: |
455-468 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guagliardo NA |
Year: |
2011 |
Journal: |
Mol Cell Endocrinol |
Title: |
TASK channels are not required to mount an aldosterone secretory response to metabolic acidosis in mice. |
Volume: |
336 |
Issue: |
1-2 |
Pages: |
47-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Manoury B |
Year: |
2011 |
Journal: |
J Physiol |
Title: |
Contractile and electrophysiological properties of pulmonary artery smooth muscle are not altered in TASK-1 knockout mice. |
Volume: |
589 |
Issue: |
Pt 13 |
Pages: |
3231-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duan W |
Year: |
2020 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
TASK-1 and TASK-3 channels modulate pressure overload-induced cardiac remodeling and dysfunction. |
Volume: |
318 |
Issue: |
3 |
Pages: |
H566-H580 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goldberg EM |
Year: |
2011 |
Journal: |
Cereb Cortex |
Title: |
Rapid developmental maturation of neocortical FS cell intrinsic excitability. |
Volume: |
21 |
Issue: |
3 |
Pages: |
666-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bista P |
Year: |
2015 |
Journal: |
J Physiol |
Title: |
Differential phospholipase C-dependent modulation of TASK and TREK two-pore domain K+ channels in rat thalamocortical relay neurons. |
Volume: |
593 |
Issue: |
1 |
Pages: |
127-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
González JA |
Year: |
2009 |
Journal: |
Eur J Neurosci |
Title: |
Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons. |
Volume: |
30 |
Issue: |
1 |
Pages: |
57-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yao C |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
TASK channels contribute to neuroprotective action of inhalational anesthetics. |
Volume: |
7 |
|
Pages: |
44203 |
|
•
•
•
•
•
|