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Search results 1 to 100 out of 276 for Kcnq2

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0.041s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Devaux JJ
Year: 2004
Journal: J Neurosci
Title: KCNQ2 is a nodal K+ channel.
Volume: 24
Issue: 5
Pages: 1236-44
Publication
First Author: Watanabe H
Year: 2000
Journal: J Neurochem
Title: Disruption of the epilepsy KCNQ2 gene results in neural hyperexcitability.
Volume: 75
Issue: 1
Pages: 28-33
Publication
First Author: Robbins J
Year: 2013
Journal: PLoS One
Title: Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents.
Volume: 8
Issue: 8
Pages: e71809
Publication  
First Author: Jing J
Year: 2022
Journal: Exp Neurol
Title: Removal of KCNQ2 from parvalbumin-expressing interneurons improves anti-seizure efficacy of retigabine.
Volume: 355
Pages: 114141
Publication  
First Author: Hou B
Year: 2023
Journal: Front Neurol
Title: KCNQ2 channels regulate the population activity of neonatal GABAergic neurons ex vivo.
Volume: 14
Pages: 1207539
Publication
First Author: Niday Z
Year: 2017
Journal: J Neurosci
Title: Epilepsy-Associated KCNQ2 Channels Regulate Multiple Intrinsic Properties of Layer 2/3 Pyramidal Neurons.
Volume: 37
Issue: 3
Pages: 576-586
Publication
First Author: Kim EC
Year: 2020
Journal: Genes Brain Behav
Title: Heterozygous loss of epilepsy gene KCNQ2 alters social, repetitive and exploratory behaviors.
Volume: 19
Issue: 1
Pages: e12599
Publication  
First Author: Tian F
Year: 2022
Journal: Neurobiol Dis
Title: Epilepsy phenotype and response to KCNQ openers in mice harboring the Kcnq2 R207W voltage-sensor mutation.
Volume: 174
Pages: 105860
Publication
First Author: Ihara Y
Year: 2016
Journal: PLoS One
Title: Retigabine, a Kv7.2/Kv7.3-Channel Opener, Attenuates Drug-Induced Seizures in Knock-In Mice Harboring Kcnq2 Mutations.
Volume: 11
Issue: 2
Pages: e0150095
Publication
First Author: Tzingounis AV
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Contribution of KCNQ2 and KCNQ3 to the medium and slow afterhyperpolarization currents.
Volume: 105
Issue: 50
Pages: 19974-9
Publication  
First Author: Hou B
Year: 2021
Journal: eNeuro
Title: Loss of KCNQ2 or KCNQ3 Leads to Multifocal Time-Varying Activity in the Neonatal Forebrain Ex Vivo.
Volume: 8
Issue: 3
Publication
First Author: Devaux JJ
Year: 2010
Journal: J Physiol
Title: The C-terminal domain of ßIV-spectrin is crucial for KCNQ2 aggregation and excitability at nodes of Ranvier.
Volume: 588
Issue: Pt 23
Pages: 4719-30
Publication
First Author: Faruk MO
Year: 2022
Journal: J Neurochem
Title: Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning.
Volume: 160
Issue: 3
Pages: 325-341
Publication
First Author: Otto JF
Year: 2006
Journal: J Neurosci
Title: A spontaneous mutation involving Kcnq2 (Kv7.2) reduces M-current density and spike frequency adaptation in mouse CA1 neurons.
Volume: 26
Issue: 7
Pages: 2053-9
Publication
First Author: McCormack T
Year: 1999
Journal: Genomics
Title: Chromosomal mapping of the potassium channel genes Kcnq2 and Kcnq3 in mouse.
Volume: 56
Issue: 3
Pages: 360-1
Publication
First Author: Soh H
Year: 2014
Journal: J Neurosci
Title: Conditional deletions of epilepsy-associated KCNQ2 and KCNQ3 channels from cerebral cortex cause differential effects on neuronal excitability.
Volume: 34
Issue: 15
Pages: 5311-21
Publication
First Author: Singh NA
Year: 2008
Journal: J Physiol
Title: Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization.
Volume: 586
Issue: 14
Pages: 3405-23
Publication
First Author: Otto JF
Year: 2009
Journal: Epilepsia
Title: Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions.
Volume: 50
Issue: 7
Pages: 1752-9
Publication
First Author: Greene DL
Year: 2018
Journal: Epilepsia
Title: Attenuating M-current suppression in vivo by a mutant Kcnq2 gene knock-in reduces seizure burden and prevents status epilepticus-induced neuronal death and epileptogenesis.
Volume: 59
Issue: 10
Pages: 1908-1918
Publication  
First Author: Tracy GC
Year: 2022
Journal: Front Behav Neurosci
Title: Heterozygous Deletion of Epilepsy Gene KCNQ2 Has Negligible Effects on Learning and Memory.
Volume: 16
Pages: 930216
Publication
First Author: Pan Z
Year: 2006
Journal: J Neurosci
Title: A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon.
Volume: 26
Issue: 10
Pages: 2599-613
Publication
First Author: Tsuboi D
Year: 2022
Journal: Cell Rep
Title: Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior.
Volume: 40
Issue: 10
Pages: 111309
Publication    
First Author: Soh H
Year: 2018
Journal: Elife
Title: Deletion of KCNQ2/3 potassium channels from PV+ interneurons leads to homeostatic potentiation of excitatory transmission.
Volume: 7
Publication
First Author: Schütze S
Year: 2016
Journal: J Biol Chem
Title: KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors.
Volume: 291
Issue: 11
Pages: 5566-75
Publication
First Author: Peters HC
Year: 2005
Journal: Nat Neurosci
Title: Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior.
Volume: 8
Issue: 1
Pages: 51-60
Publication  
First Author: Han S
Year: 2023
Journal: Neurosci Lett
Title: Inhibition of neuronal Kv7 channels ameliorates MK-801-induced cognitive dysfunction in mice via up-regulating NAMPT expression.
Volume: 814
Pages: 137471
Publication  
First Author: Wu Z
Year: 2022
Journal: Cells
Title: Paclitaxel Inhibits KCNQ Channels in Primary Sensory Neurons to Initiate the Development of Painful Peripheral Neuropathy.
Volume: 11
Issue: 24
Publication
First Author: Zhou X
Year: 2011
Journal: Cell Death Differ
Title: Novel role of KCNQ2/3 channels in regulating neuronal cell viability.
Volume: 18
Issue: 3
Pages: 493-505
Publication  
First Author: Liu W
Year: 2014
Journal: Mol Cell Neurosci
Title: Calmodulin orchestrates the heteromeric assembly and the trafficking of KCNQ2/3 (Kv7.2/3) channels in neurons.
Volume: 58
Pages: 40-52
Publication
First Author: Zhou X
Year: 2011
Journal: Exp Neurol
Title: Potential role of KCNQ/M-channels in regulating neuronal differentiation in mouse hippocampal and embryonic stem cell-derived neuronal cultures.
Volume: 229
Issue: 2
Pages: 471-83
Publication
First Author: Yang Y
Year: 2003
Journal: Hum Mol Genet
Title: Spontaneous deletion of epilepsy gene orthologs in a mutant mouse with a low electroconvulsive threshold.
Volume: 12
Issue: 9
Pages: 975-84
Publication
First Author: Kearney JA
Year: 2006
Journal: Hum Mol Genet
Title: Severe epilepsy resulting from genetic interaction between Scn2a and Kcnq2.
Volume: 15
Issue: 6
Pages: 1043-8
Publication
First Author: Kapfhamer D
Year: 2010
Journal: J Neurosci
Title: Protein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activity.
Volume: 30
Issue: 26
Pages: 8830-40
Publication
First Author: Wen H
Year: 2002
Journal: J Neurosci
Title: Calmodulin is an auxiliary subunit of KCNQ2/3 potassium channels.
Volume: 22
Issue: 18
Pages: 7991-8001
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Nakamura M
Year: 1998
Journal: Receptors Channels
Title: KQT2, a new putative potassium channel family produced by alternative splicing. Isolation, genomic structure, and alternative splicing of the putative potassium channels.
Volume: 5
Issue: 5
Pages: 255-71
Publication
First Author: Tomonoh Y
Year: 2014
Journal: PLoS One
Title: The kick-in system: a novel rapid knock-in strategy.
Volume: 9
Issue: 2
Pages: e88549
Publication
First Author: Kosenko A
Year: 2020
Journal: J Neurosci
Title: In Vivo Attenuation of M-Current Suppression Impairs Consolidation of Object Recognition Memory.
Volume: 40
Issue: 30
Pages: 5847-5856
Publication
First Author: Milh M
Year: 2020
Journal: Epilepsia
Title: A knock-in mouse model for KCNQ2-related epileptic encephalopathy displays spontaneous generalized seizures and cognitive impairment.
Volume: 61
Issue: 5
Pages: 868-878
Publication
First Author: Verneuil J
Year: 2020
Journal: PLoS Biol
Title: The M-current works in tandem with the persistent sodium current to set the speed of locomotion.
Volume: 18
Issue: 11
Pages: e3000738
Publication  
First Author: Bi Y
Year: 2011
Journal: Mol Pain
Title: Visceral hyperalgesia induced by forebrain-specific suppression of native Kv7/KCNQ/M-current in mice.
Volume: 7
Pages: 84
GXD Expression      
Probe: MGI:2660902
Assay Type: Northern blot
Annotation Date: 2003-05-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2660904
Age: embryonic day 18.5
Specimen Label: Szt1/Szt1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2660902
Assay Type: Northern blot
Annotation Date: 2003-05-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2660904
Age: embryonic day 18.5
Specimen Label: Szt1/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2660902
Assay Type: Northern blot
Annotation Date: 2003-05-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2660904
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2672842
Assay Type: RT-PCR
Annotation Date: 2003-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2672845
Age: embryonic day 11.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2672842
Assay Type: RT-PCR
Annotation Date: 2003-09-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2672845
Age: embryonic day 11.5
Specimen Label: -/-
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2672842
Assay Type: RT-PCR
Annotation Date: 2003-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2672845
Age: embryonic day 11.5
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2672842
Assay Type: RT-PCR
Annotation Date: 2003-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2672845
Age: embryonic day 11.5
Specimen Label: +/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2672842
Assay Type: RT-PCR
Annotation Date: 2003-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2672846
Age: postnatal adult
Specimen Label: +/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2672842
Assay Type: RT-PCR
Annotation Date: 2003-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2672846
Age: postnatal adult
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: brain - total
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: cortex
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755028
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: brain medulla
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: cerebellum
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: brainstem
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: olfactory bulb
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: spinal cord
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: eye
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1915328
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: harderian gland
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: heart
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: lung
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: liver
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: pancreas
Detected: false
Specimen Num: 13
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: kidney
Detected: false
Specimen Num: 14
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: spleen
Detected: false
Specimen Num: 15
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: thymus
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: lymph nodes
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: bone marrow
Detected: false
Specimen Num: 18
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: skin
Detected: false
Specimen Num: 19
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: gallbladder
Detected: true
Specimen Num: 20
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: urinary bladder
Detected: false
Specimen Num: 21
GXD Expression      
Probe: MGI:3625105
Assay Type: RT-PCR
Annotation Date: 2006-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:3625106
Age: postnatal
Specimen Label: pituitary gland
Detected: true
Specimen Num: 22