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Search results 1 to 100 out of 1053 for Kdm1a

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0.035s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Astro V
Year: 2022
Journal: iScience
Title: Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism.
Volume: 25
Issue: 7
Pages: 104665
Publication
First Author: Del Blanco B
Year: 2024
Journal: Nat Commun
Title: Kdm1a safeguards the topological boundaries of PRC2-repressed genes and prevents aging-related euchromatinization in neurons.
Volume: 15
Issue: 1
Pages: 1781
Publication
First Author: Harris WJ
Year: 2012
Journal: Cancer Cell
Title: The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells.
Volume: 21
Issue: 4
Pages: 473-87
Publication
First Author: Lambrot R
Year: 2015
Journal: FASEB J
Title: The histone demethylase KDM1A is essential for the maintenance and differentiation of spermatogonial stem cells and progenitors.
Volume: 29
Issue: 11
Pages: 4402-16
HT Experiment
Series Id: GSE66547
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Siklenka K
Year: 2015
Journal: Science
Title: Disruption of histone methylation in developing sperm impairs offspring health transgenerationally.
Volume: 350
Issue: 6261
Pages: aab2006
Publication
First Author: Myrick DA
Year: 2017
Journal: PLoS One
Title: KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice.
Volume: 12
Issue: 5
Pages: e0177473
Publication
First Author: Nagamori I
Year: 2018
Journal: Cell Rep
Title: Relationship between PIWIL4-Mediated H3K4me2 Demethylation and piRNA-Dependent DNA Methylation.
Volume: 25
Issue: 2
Pages: 350-356
Publication
First Author: Wang J
Year: 2015
Journal: Nat Neurosci
Title: LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control.
Volume: 18
Issue: 9
Pages: 1256-64
Publication
First Author: Macfarlan TS
Year: 2011
Journal: Genes Dev
Title: Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A.
Volume: 25
Issue: 6
Pages: 594-607
Publication    
First Author: Ancelin K
Year: 2016
Journal: Elife
Title: Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation.
Volume: 5
Publication
First Author: Goossens S
Year: 2017
Journal: Blood
Title: Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia.
Volume: 129
Issue: 8
Pages: 981-990
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lee C
Year: 2019
Journal: Nat Commun
Title: Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma.
Volume: 10
Issue: 1
Pages: 332
Publication
First Author: Christopher MA
Year: 2017
Journal: Nat Commun
Title: LSD1 protects against hippocampal and cortical neurodegeneration.
Volume: 8
Issue: 1
Pages: 805
Publication  
First Author: Ferdous S
Year: 2023
Journal: Front Cell Neurosci
Title: Deletion of histone demethylase Lsd1 (Kdm1a) during retinal development leads to defects in retinal function and structure.
Volume: 17
Pages: 1104592
Publication
First Author: Yu L
Year: 2021
Journal: Blood
Title: An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.
Volume: 138
Issue: 18
Pages: 1691-1704
Publication
First Author: Wang J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock.
Volume: 115
Issue: 2
Pages: E244-E252
Publication    
First Author: Wasson JA
Year: 2016
Journal: Elife
Title: Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally.
Volume: 5
Publication  
First Author: Zhang F
Year: 2014
Journal: Nat Commun
Title: Epigenetic regulation of Atrophin1 by lysine-specific demethylase 1 is required for cortical progenitor maintenance.
Volume: 5
Pages: 5815
Publication
First Author: Duteil D
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Lsd1 prevents age-programed loss of beige adipocytes.
Volume: 114
Issue: 20
Pages: 5265-5270
Publication    
First Author: Araki H
Year: 2023
Journal: Elife
Title: LSD1 defines the fiber type-selective responsiveness to environmental stress in skeletal muscle.
Volume: 12
Publication
First Author: Williams JS
Year: 2012
Journal: Am J Hypertens
Title: Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension.
Volume: 25
Issue: 7
Pages: 812-7
Publication
First Author: Pojoga LH
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension.
Volume: 301
Issue: 5
Pages: H1862-71
Publication
First Author: Huang Y
Year: 2019
Journal: J Endocrinol
Title: Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production.
Volume: 240
Issue: 2
Pages: 111-122
Publication
First Author: Rummukainen P
Year: 2022
Journal: PLoS One
Title: Lysine-Specific Demethylase 1 (LSD1) epigenetically controls osteoblast differentiation.
Volume: 17
Issue: 3
Pages: e0265027
Publication
First Author: Kim D
Year: 2018
Journal: Mol Cell
Title: PKCα-LSD1-NF-κB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response.
Volume: 69
Issue: 3
Pages: 398-411.e6
Publication
First Author: Oh C
Year: 2020
Journal: BMB Rep
Title: Inhibition of LSD1 phosphorylation alleviates colitis symptoms induced by dextran sulfate sodium.
Volume: 53
Issue: 7
Pages: 385-390
Publication  
First Author: Wang D
Year: 2020
Journal: Metabolism
Title: LSD1 mediates microbial metabolite butyrate-induced thermogenesis in brown and white adipose tissue.
Volume: 102
Pages: 154011
Publication
First Author: Chen Y
Year: 2016
Journal: Cell Chem Biol
Title: Histone Demethylase LSD1 Promotes Adipocyte Differentiation through Repressing Wnt Signaling.
Volume: 23
Issue: 10
Pages: 1228-1240
Publication
First Author: Alhousami T
Year: 2022
Journal: Mol Cancer Res
Title: Inhibition of LSD1 Attenuates Oral Cancer Development and Promotes Therapeutic Efficacy of Immune Checkpoint Blockade and YAP/TAZ Inhibition.
Volume: 20
Issue: 5
Pages: 712-721
Publication
First Author: Nair VD
Year: 2012
Journal: Mol Cell Biol
Title: Involvement of histone demethylase LSD1 in short-time-scale gene expression changes during cell cycle progression in embryonic stem cells.
Volume: 32
Issue: 23
Pages: 4861-76
Publication
First Author: Rusconi F
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: LSD1 modulates stress-evoked transcription of immediate early genes and emotional behavior.
Volume: 113
Issue: 13
Pages: 3651-6
Publication
First Author: He M
Year: 2020
Journal: Aging Cell
Title: LSD1 contributes to programmed oocyte death by regulating the transcription of autophagy adaptor SQSTM1/p62.
Volume: 19
Issue: 3
Pages: e13102
Publication
First Author: Longaretti A
Year: 2020
Journal: J Neurochem
Title: Termination of acute stress response by the endocannabinoid system is regulated through lysine-specific demethylase 1-mediated transcriptional repression of 2-AG hydrolases ABHD6 and MAGL.
Volume: 155
Issue: 1
Pages: 98-110
Publication
First Author: Engstrom AK
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration.
Volume: 117
Issue: 46
Pages: 29133-29143
Publication
First Author: Lismer A
Year: 2021
Journal: Dev Cell
Title: Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring.
Volume: 56
Issue: 5
Pages: 671-686.e6
Publication
First Author: Parmar N
Year: 2021
Journal: PLoS Pathog
Title: Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection.
Volume: 17
Issue: 3
Pages: e1009476
Publication  
First Author: Stamos DB
Year: 2021
Journal: J Exp Med
Title: The histone demethylase Lsd1 regulates multiple repressive gene programs during T cell development.
Volume: 218
Issue: 12
GXD Expression      
Probe: MGI:5300019
Assay Type: RT-PCR
Annotation Date: 2011-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599825
Stage: TS25
Assay Id: MGI:5300044
Age: embryonic day 17.5
Specimen Label: LSD1 wt
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:5300019
Assay Type: RT-PCR
Annotation Date: 2011-12-28
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3599825
Stage: TS25
Assay Id: MGI:5300044
Age: embryonic day 17.5
Specimen Label: LSD1 KO
Specimen Num: 2
GXD Expression      
Probe: MGI:5300022
Assay Type: RT-PCR
Annotation Date: 2011-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599825
Stage: TS25
Assay Id: MGI:5300045
Age: embryonic day 17.5
Specimen Label: LSD1 wt
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:5300022
Assay Type: RT-PCR
Annotation Date: 2011-12-28
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3599825
Stage: TS25
Assay Id: MGI:5300045
Age: embryonic day 17.5
Specimen Label: LSD1 KO
Specimen Num: 2
GXD Expression    
Probe: MGI:5300068
Assay Type: Northern blot
Annotation Date: 2011-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5300069
Age: postnatal adult
Image: S2
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5300068
Assay Type: Northern blot
Annotation Date: 2011-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5300069
Age: postnatal adult
Image: S2
Specimen Label: Brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5300068
Assay Type: Northern blot
Annotation Date: 2011-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5300069
Age: postnatal adult
Image: S2
Specimen Label: Skin
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5300068
Assay Type: Northern blot
Annotation Date: 2011-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5300069
Age: postnatal adult
Image: S2
Specimen Label: Lung
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5300068
Assay Type: Northern blot
Annotation Date: 2011-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5300069
Age: postnatal adult
Image: S2
Specimen Label: Liver
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5300068
Assay Type: Northern blot
Annotation Date: 2011-12-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:5300069
Age: postnatal adult
Image: S2
Specimen Label: Muscle
Specimen Num: 6
GXD Expression    
Probe: MGI:5300068
Assay Type: Northern blot
Annotation Date: 2011-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5300069
Age: postnatal adult
Image: S2
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5300068
Assay Type: Northern blot
Annotation Date: 2011-12-29
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5300069
Age: postnatal adult
Image: S2
Specimen Label: Testis
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6285857
Assay Type: RT-PCR
Annotation Date: 2019-04-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716821
Stage: TS21
Assay Id: MGI:6287384
Age: embryonic day 13.5
Image: 6
Specimen Label: +RT
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6715119
Assay Type: Western blot
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:7407210
Age: embryonic day 9.5
Image: 1
Specimen Label: E9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6715119
Assay Type: Western blot
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7407210
Age: embryonic day 12.5
Image: 1
Specimen Label: E12.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6715119
Assay Type: Western blot
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:7407210
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6715119
Assay Type: Western blot
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:7407210
Age: embryonic day 19.5
Image: 1
Specimen Label: E19.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6715119
Assay Type: Western blot
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7407210
Age: postnatal day 1
Image: 1
Specimen Label: P1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6715119
Assay Type: Western blot
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7407210
Age: postnatal day 2
Image: 1
Specimen Label: P2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6715119
Assay Type: Western blot
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7407210
Age: postnatal day 60
Image: 1
Specimen Label: P60
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:7407220
Age: embryonic day 9.5
Image: 1
Specimen Label: E9.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:7407220
Age: embryonic day 12.5
Image: 1
Specimen Label: E12.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:7407220
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:7407220
Age: embryonic day 19.5
Image: 1
Specimen Label: E19.5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7407220
Age: postnatal day 2
Image: 1
Specimen Label: P2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7407220
Age: postnatal day 8
Image: 1
Specimen Label: P8
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7407220
Age: postnatal day 16
Image: 1
Specimen Label: P16
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7407220
Age: postnatal day 30
Image: 1
Specimen Label: P30
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7407220
Age: postnatal day 60
Image: 1
Specimen Label: P60
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:7407219
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:7407220
Age: embryonic day 10.5
Image: 1
Specimen Label: E10.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7407230
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514924
Stage: TS24
Assay Id: MGI:7407240
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7407230
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514928
Stage: TS28
Assay Id: MGI:7407240
Age: postnatal month 1
Specimen Label: 1m
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7407230
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514928
Stage: TS28
Assay Id: MGI:7407240
Age: postnatal month 2
Specimen Label: 2m
Detected: true
Specimen Num: 3