Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport [, , ]. The kinesin motor activity is directed toward the microtubule's plus end. Kinesin is an oligomeric complex composed of two heavy chains and two light chains. The maintenance of the quaternary structure does not require interchain disulphide bonds.This entry represents the kinesin-like protein KIF12. It contains a kinesin-motor domain []. It has been linked to kidney disease in mice []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Mrug M |
Year: |
2005 |
Journal: |
J Am Soc Nephrol |
Title: |
Kinesin family member 12 is a candidate polycystic kidney disease modifier in the cpk mouse. |
Volume: |
16 |
Issue: |
4 |
Pages: |
905-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Katoh M |
Year: |
2005 |
Journal: |
Oncol Rep |
Title: |
Characterization of KIF12 gene in silico. |
Volume: |
13 |
Issue: |
2 |
Pages: |
367-70 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
343
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
176
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
642
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang W |
Year: |
2014 |
Journal: |
Dev Cell |
Title: |
Antioxidant signaling involving the microtubule motor KIF12 is an intracellular target of nutrition excess in beta cells. |
Volume: |
31 |
Issue: |
2 |
Pages: |
202-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mrug M |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse. |
Volume: |
10 |
Issue: |
8 |
Pages: |
e0135678 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bloom GS |
Year: |
1995 |
Journal: |
Protein Profile |
Title: |
Motor proteins 1: kinesins. |
Volume: |
2 |
Issue: |
10 |
Pages: |
1105-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brady ST |
Year: |
1995 |
Journal: |
Trends Cell Biol |
Title: |
A kinesin medley: biochemical and functional heterogeneity. |
Volume: |
5 |
Issue: |
4 |
Pages: |
159-64 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
643
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
648
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Vallee RB |
Year: |
1990 |
Journal: |
Annu Rev Biochem |
Title: |
Motor proteins of cytoplasmic microtubules. |
Volume: |
59 |
|
Pages: |
909-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakagawa T |
Year: |
1997 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. |
Volume: |
94 |
Issue: |
18 |
Pages: |
9654-9 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5641386 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-22 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:160414 |
|
Stage: |
TS04 |
Assay Id: |
MGI:5641396 |
Age: |
embryonic day 3.0 |
Image: |
4B 16-cell stage |
|
Specimen Label: |
4B 16-cell stage |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5641386 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160415 |
Pattern: |
Not Specified |
Stage: |
TS05 |
Assay Id: |
MGI:5641396 |
Age: |
embryonic day 3.5 |
Image: |
4B E3.5 |
Note: |
Expression is in centrosomes. |
Specimen Label: |
4B E3.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5641386 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160396 |
Pattern: |
Not Specified |
Stage: |
TS06 |
Assay Id: |
MGI:5641396 |
Age: |
embryonic day 4.5 |
Image: |
4B E4.5 |
Note: |
Expression is in centrosomes. |
Specimen Label: |
4B E4.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jensen N |
Year: |
2016 |
Journal: |
Neurogenetics |
Title: |
Slc20a2 is critical for maintaining a physiologic inorganic phosphate level in cerebrospinal fluid. |
Volume: |
17 |
Issue: |
2 |
Pages: |
125-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mburu P |
Year: |
2003 |
Journal: |
Nat Genet |
Title: |
Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31. |
Volume: |
34 |
Issue: |
4 |
Pages: |
421-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Courtois A |
Year: |
2012 |
Journal: |
J Cell Biol |
Title: |
The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development. |
Volume: |
198 |
Issue: |
3 |
Pages: |
357-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Winter H |
Year: |
1994 |
Journal: |
Exp Cell Res |
Title: |
Sequence and expression of murine type I hair keratins mHa2 and mHa3. |
Volume: |
212 |
Issue: |
2 |
Pages: |
190-200 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miki H |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
All kinesin superfamily protein, KIF, genes in mouse and human. |
Volume: |
98 |
Issue: |
13 |
Pages: |
7004-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Timmermans S |
Year: |
2018 |
Journal: |
JCI Insight |
Title: |
Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. |
Volume: |
3 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Niborski LL |
Year: |
2021 |
Journal: |
Dis Model Mech |
Title: |
Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. |
Volume: |
14 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Kinesin-like protein KIF12 |
Type: |
chain |
End: |
642 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
95
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
|
•
•
•
•
•
|