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Search results 1 to 100 out of 4489 for Kl

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Wilson KL
Year: 2000
Journal: Trends Cell Biol
Title: The nuclear envelope, muscular dystrophy and gene expression.
Volume: 10
Issue: 4
Pages: 125-9
Publication
First Author: Parker KL
Year: 1998
Journal: Mol Cell Endocrinol
Title: The roles of steroidogenic factor 1 in endocrine development and function.
Volume: 145
Issue: 1-2
Pages: 15-20
Publication
First Author: Ito S
Year: 2000
Journal: Mech Dev
Title: Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein.
Volume: 98
Issue: 1-2
Pages: 115-9
Publication
First Author: Utsugi T
Year: 2000
Journal: Metabolism
Title: Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging.
Volume: 49
Issue: 9
Pages: 1118-23
Publication  
First Author: Jiang W
Year: 2019
Journal: Mol Cell Endocrinol
Title: Klotho inhibits PKCα/p66SHC-mediated podocyte injury in diabetic nephropathy.
Volume: 494
Pages: 110490
Publication
First Author: Kokkinaki M
Year: 2013
Journal: J Neurosci
Title: Klotho regulates retinal pigment epithelial functions and protects against oxidative stress.
Volume: 33
Issue: 41
Pages: 16346-59
Publication
First Author: Barnes JW
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Role of fibroblast growth factor 23 and klotho cross talk in idiopathic pulmonary fibrosis.
Volume: 317
Issue: 1
Pages: L141-L154
Publication
First Author: Yamashita T
Year: 1998
Journal: J Endocrinol
Title: Elongation of the epiphyseal trabecular bone in transgenic mice carrying a klotho gene locus mutation that leads to a syndrome resembling aging.
Volume: 159
Issue: 1
Pages: 1-8
Publication
First Author: Mohlke KL
Year: 1998
Journal: Genomics
Title: Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level.
Volume: 54
Issue: 1
Pages: 19-30
Publication
First Author: Kuro-o M
Year: 1997
Journal: Nature
Title: Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
Volume: 390
Issue: 6655
Pages: 45-51
Publication
First Author: Mori K
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Disruption of klotho gene causes an abnormal energy homeostasis in mice.
Volume: 278
Issue: 3
Pages: 665-70
Publication
First Author: Kamemori M
Year: 2002
Journal: Hear Res
Title: Expression of Klotho protein in the inner ear.
Volume: 171
Issue: 1-2
Pages: 103-110
Publication
First Author: Li SA
Year: 2004
Journal: Cell Struct Funct
Title: Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice.
Volume: 29
Issue: 4
Pages: 91-9
Publication
First Author: Sasaki M
Year: 2013
Journal: Bone
Title: Altered distribution of bone matrix proteins and defective bone mineralization in klotho-deficient mice.
Volume: 57
Issue: 1
Pages: 206-19
Publication
First Author: Nagai R
Year: 2000
Journal: Cell Mol Life Sci
Title: Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases.
Volume: 57
Issue: 5
Pages: 738-46
Publication
First Author: Kawaguchi H
Year: 2000
Journal: Cell Mol Life Sci
Title: Cellular and molecular mechanism of low-turnover osteopenia in the klotho-deficient mouse.
Volume: 57
Issue: 5
Pages: 731-7
Publication
First Author: Okada S
Year: 2000
Journal: Int Immunol
Title: Impairment of B lymphopoiesis in precocious aging (klotho) mice.
Volume: 12
Issue: 6
Pages: 861-71
Publication
First Author: Ravikumar P
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: α-Klotho protects against oxidative damage in pulmonary epithelia.
Volume: 307
Issue: 7
Pages: L566-75
Publication
First Author: Suzuki H
Year: 2005
Journal: Arch Histol Cytol
Title: Histological evidence of the altered distribution of osteocytes and bone matrix synthesis in klotho-deficient mice.
Volume: 68
Issue: 5
Pages: 371-81
Publication
First Author: Chen CD
Year: 2013
Journal: J Neurosci
Title: The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS.
Volume: 33
Issue: 5
Pages: 1927-39
Publication
First Author: Yamashita T
Year: 2000
Journal: J Endocrinol
Title: High-resolution micro-computed tomography analyses of the abnormal trabecular bone structures in klotho gene mutant mice.
Volume: 164
Issue: 2
Pages: 239-45
Publication
First Author: Alesutan I
Year: 2016
Journal: Cardiovasc Res
Title: Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine.
Volume: 110
Issue: 3
Pages: 408-18
Publication
First Author: Segawa H
Year: 2007
Journal: Am J Physiol Renal Physiol
Title: Correlation between hyperphosphatemia and type II Na-Pi cotransporter activity in klotho mice.
Volume: 292
Issue: 2
Pages: F769-79
Publication
First Author: Lin Y
Year: 2015
Journal: Diabetes
Title: Antiaging Gene Klotho Attenuates Pancreatic β-Cell Apoptosis in Type 1 Diabetes.
Volume: 64
Issue: 12
Pages: 4298-311
Publication
First Author: Flenner F
Year: 2016
Journal: Cardiovasc Res
Title: Ranolazine antagonizes catecholamine-induced dysfunction in isolated cardiomyocytes, but lacks long-term therapeutic effects in vivo in a mouse model of hypertrophic cardiomyopathy.
Volume: 109
Issue: 1
Pages: 90-102
Publication
First Author: Sahu A
Year: 2018
Journal: Nat Commun
Title: Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration.
Volume: 9
Issue: 1
Pages: 4859
Publication
First Author: Kashimada K
Year: 2002
Journal: J Endocrinol
Title: Defects in growth and bone metabolism in klotho mutant mice are resistant to GH treatment.
Volume: 174
Issue: 3
Pages: 403-10
Publication
First Author: Fukino K
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Regulation of angiogenesis by the aging suppressor gene klotho.
Volume: 293
Issue: 1
Pages: 332-7
Publication
First Author: Suzuki H
Year: 2008
Journal: J Anat
Title: Histological and elemental analyses of impaired bone mineralization in klotho-deficient mice.
Volume: 212
Issue: 3
Pages: 275-85
Publication
First Author: Yamauchi M
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Wound healing delays in α-Klotho-deficient mice that have skin appearance similar to that in aged humans - Study of delayed wound healing mechanism.
Volume: 473
Issue: 4
Pages: 845-852
Publication
First Author: Yamamoto M
Year: 2005
Journal: J Biol Chem
Title: Regulation of oxidative stress by the anti-aging hormone klotho.
Volume: 280
Issue: 45
Pages: 38029-34
Publication  
First Author: Kosakai A
Year: 2011
Journal: Brain Res
Title: Degeneration of mesencephalic dopaminergic neurons in klotho mouse related to vitamin D exposure.
Volume: 1382
Pages: 109-17
Publication
First Author: Nakamura T
Year: 2002
Journal: Jpn J Pharmacol
Title: Production of nitric oxide, but not prostacyclin, is reduced in klotho mice.
Volume: 89
Issue: 2
Pages: 149-56
Publication
First Author: Kimura T
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: The impact of preserved Klotho gene expression on antioxidative stress activity in healthy kidney.
Volume: 315
Issue: 2
Pages: F345-F352
Publication
First Author: Sugiura H
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Reduced Klotho expression level in kidney aggravates renal interstitial fibrosis.
Volume: 302
Issue: 10
Pages: F1252-64
Publication
First Author: Satoh M
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Klotho protects against mouse renal fibrosis by inhibiting Wnt signaling.
Volume: 303
Issue: 12
Pages: F1641-51
Publication
First Author: Hu MC
Year: 2010
Journal: Kidney Int
Title: Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective.
Volume: 78
Issue: 12
Pages: 1240-51
Publication
First Author: Reish NJ
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: The age-regulating protein klotho is vital to sustain retinal function.
Volume: 54
Issue: 10
Pages: 6675-85
Publication
First Author: Nakamura K
Year: 2017
Journal: PLoS One
Title: Eicosapentaenoic acid prevents arterial calcification in klotho mutant mice.
Volume: 12
Issue: 8
Pages: e0181009
Publication
First Author: Voelkl J
Year: 2013
Journal: J Clin Invest
Title: Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice.
Volume: 123
Issue: 2
Pages: 812-22
Publication
First Author: Yamashita T
Year: 2000
Journal: Endocrinology
Title: Retardation in bone resorption after bone marrow ablation in klotho mutant mice.
Volume: 141
Issue: 1
Pages: 438-45
Publication
First Author: Leibrock CB
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Bicarbonate-sensitive calcification and lifespan of klotho-deficient mice.
Volume: 310
Issue: 1
Pages: F102-8
Publication
First Author: Jorge LB
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Klotho deficiency aggravates sepsis-related multiple organ dysfunction.
Volume: 316
Issue: 3
Pages: F438-F448
Publication
First Author: Nagai T
Year: 2003
Journal: FASEB J
Title: Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress.
Volume: 17
Issue: 1
Pages: 50-2
Publication
First Author: Coelho FO
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Chronic nicotine exposure reduces klotho expression and triggers different renal and hemodynamic responses in klotho-haploinsufficient mice.
Volume: 314
Issue: 5
Pages: F992-F998
Publication
First Author: Masuda H
Year: 2005
Journal: Mech Ageing Dev
Title: Regulation of multiple ageing-like phenotypes by inducible klotho gene expression in klotho mutant mice.
Volume: 126
Issue: 12
Pages: 1274-83
Publication
First Author: Imura A
Year: 2007
Journal: Science
Title: alpha-Klotho as a regulator of calcium homeostasis.
Volume: 316
Issue: 5831
Pages: 1615-8
Publication
First Author: Carpinelli MR
Year: 2011
Journal: Hear Res
Title: Vitamin D-deficient diet rescues hearing loss in Klotho mice.
Volume: 275
Issue: 1-2
Pages: 105-9
Publication
First Author: Manabe N
Year: 2001
Journal: J Immunol
Title: Connection between B lymphocyte and osteoclast differentiation pathways.
Volume: 167
Issue: 5
Pages: 2625-31
Publication
First Author: Nakano-Kurimoto R
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition.
Volume: 297
Issue: 5
Pages: H1673-84
Publication
First Author: Yahata K
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Regulation of stanniocalcin 1 and 2 expression in the kidney by klotho gene.
Volume: 310
Issue: 1
Pages: 128-34
Publication
First Author: Lin Y
Year: 2013
Journal: Endocrinology
Title: Genetic deficiency of anti-aging gene klotho exacerbates early nephropathy in STZ-induced diabetes in male mice.
Volume: 154
Issue: 10
Pages: 3855-63
Publication
First Author: Fischer SS
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: Hyperaldosteronism in Klotho-deficient mice.
Volume: 299
Issue: 5
Pages: F1171-7
Publication  
First Author: Porter T
Year: 2019
Journal: Neurobiol Aging
Title: Klotho allele status is not associated with Aβ and APOE ε4-related cognitive decline in preclinical Alzheimer's disease.
Volume: 76
Pages: 162-165
Publication
First Author: Shiozaki M
Year: 2008
Journal: Neuroscience
Title: Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice.
Volume: 152
Issue: 4
Pages: 924-41
Publication
First Author: Gui T
Year: 2012
Journal: Lab Invest
Title: MicroRNAs that target Ca(2+) transporters are involved in vascular smooth muscle cell calcification.
Volume: 92
Issue: 9
Pages: 1250-9
Publication
First Author: Fan J
Year: 2016
Journal: Stem Cells
Title: The Antiaging Gene Klotho Regulates Proliferation and Differentiation of Adipose-Derived Stem Cells.
Volume: 34
Issue: 6
Pages: 1615-25
Publication
First Author: Kawaguchi H
Year: 1999
Journal: J Clin Invest
Title: Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia.
Volume: 104
Issue: 3
Pages: 229-37
Publication
First Author: Suga T
Year: 2000
Journal: Am J Respir Cell Mol Biol
Title: Disruption of the klotho gene causes pulmonary emphysema in mice. Defect in maintenance of pulmonary integrity during postnatal life.
Volume: 22
Issue: 1
Pages: 26-33
Publication
First Author: Min D
Year: 2007
Journal: Blood
Title: Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging.
Volume: 109
Issue: 6
Pages: 2529-37
Publication
First Author: Takahashi M
Year: 2012
Journal: PLoS One
Title: Reduction of type IV collagen by upregulated miR-29 in normal elderly mouse and klotho-deficient, senescence-model mouse.
Volume: 7
Issue: 11
Pages: e48974
Publication
First Author: Toyama R
Year: 2006
Journal: Endocrinology
Title: Impaired regulation of gonadotropins leads to the atrophy of the female reproductive system in klotho-deficient mice.
Volume: 147
Issue: 1
Pages: 120-9
Publication
First Author: Shumilina E
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: Altered regulation of cytosolic Ca²⁺ concentration in dendritic cells from klotho hypomorphic mice.
Volume: 305
Issue: 1
Pages: C70-7
Publication
First Author: Yoshida T
Year: 2002
Journal: Endocrinology
Title: Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene.
Volume: 143
Issue: 2
Pages: 683-9
Publication
First Author: Borst O
Year: 2014
Journal: FASEB J
Title: 1,25(OH)2 vitamin D3-dependent inhibition of platelet Ca2+ signaling and thrombus formation in klotho-deficient mice.
Volume: 28
Issue: 5
Pages: 2108-19
Publication
First Author: Yamashita T
Year: 2001
Journal: J Endocrinol
Title: Klotho-deficient mice are resistant to bone loss induced by unloading due to sciatic neurectomy.
Volume: 168
Issue: 2
Pages: 347-51
Publication
First Author: Hu MC
Year: 2011
Journal: J Am Soc Nephrol
Title: Klotho deficiency causes vascular calcification in chronic kidney disease.
Volume: 22
Issue: 1
Pages: 124-36
Publication
First Author: Sopjani M
Year: 2011
Journal: FEBS Lett
Title: Regulation of the Na+/K+ ATPase by Klotho.
Volume: 585
Issue: 12
Pages: 1759-64
Publication
First Author: Fernández ÁF
Year: 2018
Journal: Nature
Title: Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.
Volume: 558
Issue: 7708
Pages: 136-140
Publication
First Author: Brownstein CA
Year: 2010
Journal: Endocrinology
Title: Increased bone volume and correction of HYP mouse hypophosphatemia in the Klotho/HYP mouse.
Volume: 151
Issue: 2
Pages: 492-501
Publication
First Author: Faul C
Year: 2011
Journal: J Clin Invest
Title: FGF23 induces left ventricular hypertrophy.
Volume: 121
Issue: 11
Pages: 4393-408
Publication
First Author: Sato A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Morphological mechanism of the development of pulmonary emphysema in klotho mice.
Volume: 104
Issue: 7
Pages: 2361-5
Publication
First Author: Hikone K
Year: 2017
Journal: J Histochem Cytochem
Title: Histochemical Examination on Periodontal Tissues of Klotho-Deficient Mice Fed With Phosphate-Insufficient Diet.
Volume: 65
Issue: 4
Pages: 207-221
Publication
First Author: Gao D
Year: 2016
Journal: Hypertension
Title: Activation of SIRT1 Attenuates Klotho Deficiency-Induced Arterial Stiffness and Hypertension by Enhancing AMP-Activated Protein Kinase Activity.
Volume: 68
Issue: 5
Pages: 1191-1199
Publication  
First Author: Liu L
Year: 2018
Journal: J Mol Cell Cardiol
Title: High phosphate-induced downregulation of PPARγ contributes to CKD-associated vascular calcification.
Volume: 114
Pages: 264-275
Publication
First Author: Urakawa I
Year: 2006
Journal: Nature
Title: Klotho converts canonical FGF receptor into a specific receptor for FGF23.
Volume: 444
Issue: 7120
Pages: 770-4
Publication
First Author: Izbeki F
Year: 2010
Journal: J Physiol
Title: Loss of Kitlow progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice.
Volume: 588
Issue: Pt 16
Pages: 3101-17
Publication
First Author: Brobey RK
Year: 2015
Journal: PLoS One
Title: Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways.
Volume: 10
Issue: 10
Pages: e0139914
Publication
First Author: Kusaba T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity.
Volume: 107
Issue: 45
Pages: 19308-13
Publication
First Author: Chen J
Year: 2016
Journal: Aging Cell
Title: Deficiency in the anti-aging gene Klotho promotes aortic valve fibrosis through AMPKα-mediated activation of RUNX2.
Volume: 15
Issue: 5
Pages: 853-60
Publication
First Author: Wehling-Henricks M
Year: 2016
Journal: Hum Mol Genet
Title: Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy.
Volume: 25
Issue: 12
Pages: 2465-2482
Publication
First Author: Asai O
Year: 2012
Journal: Kidney Int
Title: Decreased renal α-Klotho expression in early diabetic nephropathy in humans and mice and its possible role in urinary calcium excretion.
Volume: 81
Issue: 6
Pages: 539-47
Publication
First Author: Asada N
Year: 2013
Journal: Cell Stem Cell
Title: Matrix-embedded osteocytes regulate mobilization of hematopoietic stem/progenitor cells.
Volume: 12
Issue: 6
Pages: 737-47
Publication
First Author: Shiraki-Iida T
Year: 1998
Journal: FEBS Lett
Title: Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein.
Volume: 424
Issue: 1-2
Pages: 6-10
Publication
First Author: Kurosu H
Year: 2005
Journal: Science
Title: Suppression of aging in mice by the hormone Klotho.
Volume: 309
Issue: 5742
Pages: 1829-33
Publication
First Author: Ohnishi M
Year: 2011
Journal: FASEB J
Title: Dietary and genetic evidence for enhancing glucose metabolism and reducing obesity by inhibiting klotho functions.
Volume: 25
Issue: 6
Pages: 2031-9
Publication
First Author: Xing Y
Year: 2018
Journal: J Immunol
Title: Thymic Epithelial Cell Support of Thymopoiesis Does Not Require Klotho.
Volume: 201
Issue: 11
Pages: 3320-3328
Publication
First Author: Tucker Zhou TB
Year: 2013
Journal: J Biol Chem
Title: Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk.
Volume: 288
Issue: 51
Pages: 36302-11
Publication  
First Author: Laszczyk AM
Year: 2017
Journal: Neurobiol Aging
Title: Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss.
Volume: 59
Pages: 41-54
Publication
First Author: Tsujikawa H
Year: 2003
Journal: Mol Endocrinol
Title: Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system.
Volume: 17
Issue: 12
Pages: 2393-403
Publication
First Author: Vanhooren V
Year: 2011
Journal: Aging Cell
Title: Alteration in N-glycomics during mouse aging: a role for FUT8.
Volume: 10
Issue: 6
Pages: 1056-66
Publication
First Author: Hum JM
Year: 2017
Journal: J Am Soc Nephrol
Title: Chronic Hyperphosphatemia and Vascular Calcification Are Reduced by Stable Delivery of Soluble Klotho.
Volume: 28
Issue: 4
Pages: 1162-1174
Publication
First Author: Takei Y
Year: 2012
Journal: Bone
Title: Stanniocalcin 2 is associated with ectopic calcification in α-klotho mutant mice and inhibits hyperphosphatemia-induced calcification in aortic vascular smooth muscle cells.
Volume: 50
Issue: 4
Pages: 998-1005
Publication
First Author: Haruna Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Amelioration of progressive renal injury by genetic manipulation of Klotho gene.
Volume: 104
Issue: 7
Pages: 2331-6
Publication
First Author: Eren M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.
Volume: 111
Issue: 19
Pages: 7090-5
Publication
First Author: Voelkl J
Year: 2018
Journal: J Clin Invest
Title: SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling.
Volume: 128
Issue: 7
Pages: 3024-3040