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Search results 1 to 77 out of 77 for Klhl30

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Kelch-like protein 30 (KLHL30) belongs to the KLHL family []. Its function is not clear.The KLHL (Kelch-like) proteins generally have a BTB/POZ domain, a BACK domain, and five to six Kelch motifs. They constitute a subgroup at the intersection between the BTB/POZ domain and Kelch domain superfamilies. The BTB/POZ domain facilitates protein binding [], while the Kelch domain (repeats) form β-propellers. The Kelch superfamily of proteins can be subdivided into five groups: (1) N-propeller, C-dimer proteins, (2) N-propeller proteins, (3) propeller proteins, (4) N-dimer, C-propeller proteins, and (5) C-propeller proteins. KLHL family members belong to the N-dimer, C-propeller subclass of Kelch repeat proteins []. In addition to BTB/POZ and Kelch domains, the KLHL family members contain a BACK domain, first described as a 130-residue region of conservation observed amongst BTB-Kelch proteins []. Many of the Kelch-like proteins have been identified as adaptors for the recruitment of substrates to Cul3-based E3 ubiquitin ligases [, ].
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 581  
Fragment?: false
Publication
First Author: Stogios PJ
Year: 2004
Journal: Trends Biochem Sci
Title: The BACK domain in BTB-kelch proteins.
Volume: 29
Issue: 12
Pages: 634-7
Publication  
First Author: Dhanoa BS
Year: 2013
Journal: Hum Genomics
Title: Update on the Kelch-like (KLHL) gene family.
Volume: 7
Pages: 13
Publication
First Author: Adams J
Year: 2000
Journal: Trends Cell Biol
Title: The kelch repeat superfamily of proteins: propellers of cell function.
Volume: 10
Issue: 1
Pages: 17-24
Publication
First Author: Furukawa M
Year: 2003
Journal: Nat Cell Biol
Title: Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.
Volume: 5
Issue: 11
Pages: 1001-7
Publication
First Author: Oberg EA
Year: 2012
Journal: J Biol Chem
Title: Selective proteasomal degradation of the B'β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15.
Volume: 287
Issue: 52
Pages: 43378-89
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:7549384
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7549383
Age: postnatal week 10
Image: 1
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7549384
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7549383
Age: postnatal week 10
Image: 1
Specimen Label: Lung
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:7549384
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7549383
Age: postnatal week 10
Image: 1
Specimen Label: Liver
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:7549384
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7549383
Age: postnatal week 10
Image: 1
Specimen Label: Kidney
Specimen Num: 4
GXD Expression    
Probe: MGI:7549384
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7549383
Age: postnatal week 10
Image: 1
Specimen Label: Spleen
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:7549384
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:7549383
Age: postnatal week 10
Image: 1
Specimen Label: Fat
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:7549384
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7549383
Age: postnatal week 10
Image: 1
Specimen Label: Brain
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:7549384
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:7549383
Age: postnatal week 10
Image: 1
Specimen Label: Femur
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:7549384
Assay Type: RT-PCR
Annotation Date: 2023-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768128
Stage: TS28
Assay Id: MGI:7549383
Age: postnatal week 10
Image: 1
Specimen Label: Calvaria
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:3793746
Assay Type: RNA in situ
Annotation Date: 2008-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1634216
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:3793756
Age: embryonic day 9.5
Image: E9.5
Note: Expression in the inflow tract and a portion of the common atria.
Specimen Label: E9.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3793746
Assay Type: RNA in situ
Annotation Date: 2008-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610516
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:3793756
Age: embryonic day 9.5
Image: E9.5
Note: Expression in the inflow tract and a portion of the common atria.
Specimen Label: E9.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3793746
Assay Type: RNA in situ
Annotation Date: 2008-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611716
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:3793756
Age: embryonic day 9.5
Image: E9.5
Specimen Label: E9.5
Detected: true
Specimen Num: 1
Publication
First Author: Christoforou N
Year: 2008
Journal: J Clin Invest
Title: Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes.
Volume: 118
Issue: 3
Pages: 894-903
Publication  
First Author: Yorgan TA
Year: 2019
Journal: Bone
Title: Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.
Volume: 127
Pages: 155-163
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform