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Search results 1 to 100 out of 103 for Klhl6

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
89857 | KLHL6
Type: gene
Organism: human
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Gene
527363 | KLHL6
Type: gene
Organism: cattle
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Gene
424762 | KLHL6
Type: gene
Organism: chicken
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Gene
368818 | klhl6
Type: gene
Organism: zebrafish
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Gene
705455 | KLHL6
Type: gene
Organism: macaque, rhesus
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Gene
100486936 | klhl6
Type: gene
Organism: frog, western clawed
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Gene
287974 | Klhl6
Type: gene
Organism: rat
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Gene
488096 | KLHL6
Type: gene
Organism: dog, domestic
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Gene
735440 | KLHL6
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2686922 | Klhl6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029851 | KLHL6
Type: Family
Description: Kelch-like protein 6 (KLHL6) is involved in B-lymphocyte antigen receptor signalling and germinal centre formation []. Mutations in KLHL6 gene have been linked to chronic lymphocytic leukaemia (CLL) [].The KLHL (Kelch-like) proteins generally have a BTB/POZ domain, a BACK domain, and five to six Kelch motifs. They constitute a subgroup at the intersection between the BTB/POZ domain and Kelch domain superfamilies. The BTB/POZ domain facilitates protein binding [], while the Kelch domain (repeats) form β-propellers. The Kelch superfamily of proteins can be subdivided into five groups: (1) N-propeller, C-dimer proteins, (2) N-propeller proteins, (3) propeller proteins, (4) N-dimer, C-propeller proteins, and (5) C-propeller proteins. KLHL family members belong to the N-dimer, C-propeller subclass of Kelch repeat proteins []. In addition to BTB/POZ and Kelch domains, the KLHL family members contain a BACK domain, first described as a 130-residue region of conservation observed amongst BTB-Kelch proteins []. Many of the Kelch-like proteins have been identified as adaptors for the recruitment of substrates to Cul3-based E3 ubiquitin ligases [, ].
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Publication
16166635 | J:101363
First Author: Kroll J
Year: 2005
Journal: Mol Cell Biol
Title: The BTB-kelch protein KLHL6 is involved in B-lymphocyte antigen receptor signaling and germinal center formation.
Volume: 25
Issue: 19
Pages: 8531-40
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Gene
100874019 | KLHL6-AS1
Type: gene
Organism: human
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Publication
28807996 | J:250892
First Author: Bertocci B
Year: 2017
Journal: J Immunol
Title: Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation.
Volume: 199
Issue: 7
Pages: 2408-2420
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Protein
Q6V595
Organism: Mus musculus/domesticus
Length: 619  
Fragment?: false
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Publication
10603472 | -
First Author: Adams J
Year: 2000
Journal: Trends Cell Biol
Title: The kelch repeat superfamily of proteins: propellers of cell function.
Volume: 10
Issue: 1
Pages: 17-24
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Publication
14528312 | -
First Author: Furukawa M
Year: 2003
Journal: Nat Cell Biol
Title: Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.
Volume: 5
Issue: 11
Pages: 1001-7
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Publication
23135275 | -
First Author: Oberg EA
Year: 2012
Journal: J Biol Chem
Title: Selective proteasomal degradation of the B'β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15.
Volume: 287
Issue: 52
Pages: 43378-89
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Publication
15544948 | -
First Author: Stogios PJ
Year: 2004
Journal: Trends Biochem Sci
Title: The BACK domain in BTB-kelch proteins.
Volume: 29
Issue: 12
Pages: 634-7
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Publication
23676014 | -
 
First Author: Dhanoa BS
Year: 2013
Journal: Hum Genomics
Title: Update on the Kelch-like (KLHL) gene family.
Volume: 7
Pages: 13
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Publication
- | J:272396
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for heights.
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Publication
- | J:267699
     
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Parula.
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Publication
- | J:272394
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for torres_del_paine.
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Publication
- | J:265168
     
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for blossom.
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Publication
- | J:265167
     
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for cerulean.
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Publication
- | J:272395
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Ascension.
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Protein Coding Gene
MGP_CAROLIEiJ_G0020569 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022635 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022572 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022366 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2686922 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023052 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021896 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022338 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022470 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022537 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022465 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0023063 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021637 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021940 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016273 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021466 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12617994 | J:87056
First Author: Gupta-Rossi N
Year: 2003
Journal: Mol Immunol
Title: Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells.
Volume: 39
Issue: 13
Pages: 791-9
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Publication
- | J:274963
     
First Author: Choi JH
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Lazuli.
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Publication
- | J:272397
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Besmirched.
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GXD Expression
GXD Expression
 
Probe: MGI:4424672
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825806
Age: embryonic day 14.5
Image: euxassay_011427_12
Specimen Label: euxassay_011427_12
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4424672
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825806
Age: embryonic day 14.5
Image: euxassay_011427_13
Specimen Label: euxassay_011427_13
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4424672
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825806
Age: embryonic day 14.5
Image: euxassay_011427_14
Specimen Label: euxassay_011427_14
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4424672
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825806
Age: embryonic day 14.5
Image: euxassay_011427_15
Specimen Label: euxassay_011427_15
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4424672
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825806
Age: embryonic day 14.5
Image: euxassay_011427_16
Specimen Label: euxassay_011427_16
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:1771207
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274312
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:5291699
Age: embryonic day 8.0
Image: E8.0
Note: Expression is present in the vasculature.
Specimen Label: E8.0
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1771207
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274313
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5291699
Age: embryonic day 8.5
Image: E8.5
Note: Expression is present in the vasculature.
Specimen Label: E8.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1771207
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619112
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:5291699
Age: embryonic day 8.0
Image: E8.0
Note: Expression is present in the posterior notochord.
Specimen Label: E8.0
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1771207
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619113
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5291699
Age: embryonic day 8.5
Image: E8.5
Note: Expression is present in the posterior notochord.
Specimen Label: E8.5
Detected: true
Specimen Num: 2
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Publication
21822279 | J:176969
First Author: Costello I
Year: 2011
Journal: Nat Cell Biol
Title: The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation.
Volume: 13
Issue: 9
Pages: 1084-91
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Publication
- | J:104190
     
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
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Publication
23012479 | J:190322
First Author: Archambaud C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Impact of lactobacilli on orally acquired listeriosis.
Volume: 109
Issue: 41
Pages: 16684-9
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Publication
22008794 | J:143778
First Author: Tamplin OJ
Year: 2011
Journal: Dev Biol
Title: Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.
Volume: 360
Issue: 2
Pages: 415-25
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Allele
Klhl6<tm1Btoci> | MGI:5882711
Name: kelch-like 6; targeted mutation 1, Barbara Bertocci
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:5882713 | B6;129P2-Klhl6<tm1Btoci>/Orl
Attribute String: mutant stock, targeted mutation
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Protein Coding Gene
MGI:1196453 | Klhl7
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Klhl6<M5Btlr> | MGI:6284786
Name: kelch-like 6; mutation 5, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Klhl6<m6Btlr> | MGI:6284790
Name: kelch-like 6; mutation 6, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6284791 | C57BL/6J-Klhl6<m6Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Allele
Klhl6<M3Btlr> | MGI:6269425
Name: kelch-like 6; mutation 3, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6269426 | C57BL/6J-Klhl6<M3Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Allele
Klhl6<m4Btlr> | MGI:6284782
Name: kelch-like 6; mutation 4, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6284783 | C57BL/6J-Klhl6<m4Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Allele
Klhl6<m2Btlr> | MGI:6200017
Name: kelch-like 6; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6200018 | C57BL/6J-Klhl6<m2Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Allele
Klhl6<m1Btlr> | MGI:6200013
Name: kelch-like 6; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6200014 | C57BL/6J-Klhl6<m1Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Strain
MGI:6284787 | C57BL/6J-Klhl6<M5Btlr>
Attribute String: chemically induced mutation, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Klhl6/Klhl6
Background: C57BL/6J-Klhl6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Klhl6/Klhl6
Background: C57BL/6J-Klhl6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Klhl6/Klhl6
Background: C57BL/6J-Klhl6
Zygosity: hm
Has Mutant Allele: true
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