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Search results 1 to 79 out of 79 for Klk5

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
25818 | KLK5
Type: gene
Organism: human
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Gene
617418 | KLK5
Type: gene
Organism: cattle
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Gene
719467 | KLK5
Type: gene
Organism: macaque, rhesus
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Gene
102546758 | Klk5
Type: gene
Organism: rat
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Gene
484353 | KLK5
Type: gene
Organism: dog, domestic
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Gene
748162 | KLK5
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1915918 | Klk5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26390218 | J:228907
First Author: Furio L
Year: 2015
Journal: PLoS Genet
Title: KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome.
Volume: 11
Issue: 9
Pages: e1005389
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Publication
31381994 | J:280086
First Author: Pampalakis G
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Elimination of KLK5 inhibits early skin tumorigenesis by reducing epidermal proteolysis and reinforcing epidermal microstructure.
Volume: 1865
Issue: 11
Pages: 165520
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Publication
28095415 | J:238698
First Author: Kasparek P
Year: 2017
Journal: PLoS Genet
Title: KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.
Volume: 13
Issue: 1
Pages: e1006566
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Publication
32461336 | J:344772
 
First Author: Azouz NP
Year: 2020
Journal: Sci Transl Med
Title: Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis.
Volume: 12
Issue: 545
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Publication
35487308 | J:331721
First Author: Jackman JK
Year: 2022
Journal: J Allergy Clin Immunol
Title: Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma.
Volume: 150
Issue: 4
Pages: 972-978.e7
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Publication
32442469 | J:300922
First Author: Zingkou E
Year: 2020
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Cathelicidin represents a new target for manipulation of skin inflammation in Netherton syndrome.
Volume: 1866
Issue: 10
Pages: 165831
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Protein Coding Gene
MGP_CAROLIEiJ_G0029643 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032146 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032131 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032136 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031852 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915918 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031821 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031931 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032049 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012871 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030742 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
31912553 | J:302081
First Author: Zingkou E
Year: 2020
Journal: J Dermatol
Title: Exacerbated dandruff in the absence of kallikrein-related peptidase 5 protease.
Volume: 47
Issue: 3
Pages: 311-313
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: A135X/A135X
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: Klk5-/-; A135X/A135X
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: Klk7-/-; A135X/A135X
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: Klk5-/-; Klk7-/-; A135X/A135X
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: Klk5-/-; Klk7-/-
Detected: false
Specimen Num: 6
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Publication
15192120 | J:90945
First Author: Borgoño CA
Year: 2004
Journal: Mol Cancer Res
Title: Human tissue kallikreins: physiologic roles and applications in cancer.
Volume: 2
Issue: 5
Pages: 257-80
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Publication
27551807 | J:262458
First Author: Zhang L
Year: 2016
Journal: PLoS One
Title: Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.
Volume: 11
Issue: 8
Pages: e0161465
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Publication
20627083 | J:163847
First Author: Schaffer AE
Year: 2010
Journal: Dev Cell
Title: Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.
Volume: 18
Issue: 6
Pages: 1022-9
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Publication
15203212 | J:90604
First Author: Olsson AY
Year: 2004
Journal: Genomics
Title: Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.
Volume: 84
Issue: 1
Pages: 147-56
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
36516271 | J:335297
First Author: Chavarria-Smith J
Year: 2022
Journal: Sci Transl Med
Title: Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Volume: 14
Issue: 675
Pages: eabp9159
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Allele
Klk5<tm1.1Rase> | MGI:5824547
Name: kallikrein related-peptidase 5; targeted mutation 1.1, Radislav Sedlacek
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Protein Coding Gene
MGI:892020 | Klk1b5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P15945
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Publication
24534191 | J:210758
First Author: Furio L
Year: 2014
Journal: J Exp Med
Title: Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome.
Volume: 211
Issue: 3
Pages: 499-513
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Allele
Tg(IVL-KLK5)#Hov | MGI:5583016
Name: transgene insertion, Alain Hovnanian
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(IVL-KLK5)#Hov/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Publication
24352040 | J:208056
First Author: Fischer J
Year: 2014
Journal: J Invest Dermatol
Title: Characterization of Spink6 in mouse skin: the conserved inhibitor of kallikrein-related peptidases is reduced by barrier injury.
Volume: 134
Issue: 5
Pages: 1305-1312
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Publication
19414552 | J:148493
First Author: Briot A
Year: 2009
Journal: J Exp Med
Title: Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome.
Volume: 206
Issue: 5
Pages: 1135-47
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Publication
17596512 | J:128293
First Author: Deraison C
Year: 2007
Journal: Mol Biol Cell
Title: LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction.
Volume: 18
Issue: 9
Pages: 3607-19
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Publication
32169475 | J:297220
First Author: Gouin O
Year: 2020
Journal: J Invest Dermatol
Title: Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature.
Volume: 140
Issue: 6
Pages: 1184-1194
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