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Search results 1 to 83 out of 83 for Klk5

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
25818 | KLK5
Type: gene
Organism: human
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Gene
484353 | KLK5
Type: gene
Organism: dog, domestic
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Gene
748162 | KLK5
Type: gene
Organism: chimpanzee
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Gene
617418 | KLK5
Type: gene
Organism: cattle
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Gene
719467 | KLK5
Type: gene
Organism: macaque, rhesus
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Gene
102546758 | Klk5
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1915918 | Klk5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26390218 | J:228907
First Author: Furio L
Year: 2015
Journal: PLoS Genet
Title: KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome.
Volume: 11
Issue: 9
Pages: e1005389
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Publication
31381994 | J:280086
First Author: Pampalakis G
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Elimination of KLK5 inhibits early skin tumorigenesis by reducing epidermal proteolysis and reinforcing epidermal microstructure.
Volume: 1865
Issue: 11
Pages: 165520
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Publication
28095415 | J:238698
First Author: Kasparek P
Year: 2017
Journal: PLoS Genet
Title: KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.
Volume: 13
Issue: 1
Pages: e1006566
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Publication
32461336 | J:344772
 
First Author: Azouz NP
Year: 2020
Journal: Sci Transl Med
Title: Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis.
Volume: 12
Issue: 545
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Publication
35487308 | J:331721
First Author: Jackman JK
Year: 2022
Journal: J Allergy Clin Immunol
Title: Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma.
Volume: 150
Issue: 4
Pages: 972-978.e7
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Publication
32442469 | J:300922
First Author: Zingkou E
Year: 2020
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Cathelicidin represents a new target for manipulation of skin inflammation in Netherton syndrome.
Volume: 1866
Issue: 10
Pages: 165831
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Protein Coding Gene
MGP_CAROLIEiJ_G0029643 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032146 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032131 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032136 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031852 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915918 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031821 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031931 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032049 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012871 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030742 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
31912553 | J:302081
First Author: Zingkou E
Year: 2020
Journal: J Dermatol
Title: Exacerbated dandruff in the absence of kallikrein-related peptidase 5 protease.
Volume: 47
Issue: 3
Pages: 311-313
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: A135X/A135X
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: Klk5-/-; A135X/A135X
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: Klk7-/-; A135X/A135X
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: Klk5-/-; Klk7-/-; A135X/A135X
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7484224
Assay Type: RT-PCR
Annotation Date: 2023-05-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3639227
Stage: TS27
Assay Id: MGI:7484308
Age: postnatal newborn
Image: 2
Specimen Label: Klk5-/-; Klk7-/-
Detected: false
Specimen Num: 6
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Publication
15192120 | J:90945
First Author: Borgoño CA
Year: 2004
Journal: Mol Cancer Res
Title: Human tissue kallikreins: physiologic roles and applications in cancer.
Volume: 2
Issue: 5
Pages: 257-80
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Publication
27551807 | J:262458
First Author: Zhang L
Year: 2016
Journal: PLoS One
Title: Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.
Volume: 11
Issue: 8
Pages: e0161465
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Publication
20627083 | J:163847
First Author: Schaffer AE
Year: 2010
Journal: Dev Cell
Title: Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.
Volume: 18
Issue: 6
Pages: 1022-9
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Publication
15203212 | J:90604
First Author: Olsson AY
Year: 2004
Journal: Genomics
Title: Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.
Volume: 84
Issue: 1
Pages: 147-56
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
36516271 | J:335297
First Author: Chavarria-Smith J
Year: 2022
Journal: Sci Transl Med
Title: Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Volume: 14
Issue: 675
Pages: eabp9159
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Allele
Klk5<tm1.1Rase> | MGI:5824547
Name: kallikrein related-peptidase 5; targeted mutation 1.1, Radislav Sedlacek
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Protein Coding Gene
MGI:892020 | Klk1b5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P15945
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Publication
24534191 | J:210758
First Author: Furio L
Year: 2014
Journal: J Exp Med
Title: Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome.
Volume: 211
Issue: 3
Pages: 499-513
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Allele
Tg(IVL-KLK5)#Hov | MGI:5583016
Name: transgene insertion, Alain Hovnanian
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(IVL-KLK5)#Hov/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Publication
38316920 | J:357366
First Author: Petrova E
Year: 2024
Journal: Commun Biol
Title: Comparative analyses of Netherton syndrome patients and Spink5 conditional knock-out mice uncover disease-relevant pathways.
Volume: 7
Issue: 1
Pages: 152
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Publication
24352040 | J:208056
First Author: Fischer J
Year: 2014
Journal: J Invest Dermatol
Title: Characterization of Spink6 in mouse skin: the conserved inhibitor of kallikrein-related peptidases is reduced by barrier injury.
Volume: 134
Issue: 5
Pages: 1305-1312
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Publication
19414552 | J:148493
First Author: Briot A
Year: 2009
Journal: J Exp Med
Title: Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome.
Volume: 206
Issue: 5
Pages: 1135-47
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Publication
17596512 | J:128293
First Author: Deraison C
Year: 2007
Journal: Mol Biol Cell
Title: LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction.
Volume: 18
Issue: 9
Pages: 3607-19
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Publication
32169475 | J:297220
First Author: Gouin O
Year: 2020
Journal: J Invest Dermatol
Title: Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature.
Volume: 140
Issue: 6
Pages: 1184-1194
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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