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Search results 1 to 100 out of 102 for Knl1

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0.042s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Krenn V
Year: 2012
Journal: J Cell Biol
Title: Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction.
Volume: 196
Issue: 4
Pages: 451-67
Publication
First Author: Shi L
Year: 2019
Journal: Nat Commun
Title: Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion.
Volume: 10
Issue: 1
Pages: 2588
Publication
First Author: Vleugel M
Year: 2013
Journal: J Cell Biol
Title: Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation.
Volume: 203
Issue: 6
Pages: 943-55
Publication
First Author: Yue W
Year: 2022
Journal: FASEB J
Title: Kinetochore scaffold 1 regulates SAC function during mouse oocyte meiotic maturation.
Volume: 36
Issue: 3
Pages: e22210
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:7341769
Assay Type: RT-PCR
Annotation Date: 2022-10-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:7341772
Age: embryonic day 11.5
Image: S2
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_02
Specimen Label: euxassay_015807_02
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_03
Specimen Label: euxassay_015807_03
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_04
Specimen Label: euxassay_015807_04
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_05
Specimen Label: euxassay_015807_05
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_06
Specimen Label: euxassay_015807_06
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_07
Specimen Label: euxassay_015807_07
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_08
Specimen Label: euxassay_015807_08
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_09
Specimen Label: euxassay_015807_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_10
Specimen Label: euxassay_015807_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_11
Specimen Label: euxassay_015807_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_12
Specimen Label: euxassay_015807_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_13
Specimen Label: euxassay_015807_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_14
Specimen Label: euxassay_015807_14
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_15
Specimen Label: euxassay_015807_15
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_16
Specimen Label: euxassay_015807_16
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_17
Specimen Label: euxassay_015807_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_18
Specimen Label: euxassay_015807_18
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_19
Specimen Label: euxassay_015807_19
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_20
Specimen Label: euxassay_015807_20
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:4426786
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4823639
Age: embryonic day 14.5
Image: euxassay_015807_21
Specimen Label: euxassay_015807_21
Detected: true
Specimen Num: 20
Publication
First Author: Mora-Bermúdez F
Year: 2022
Journal: Sci Adv
Title: Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development.
Volume: 8
Issue: 30
Pages: eabn7702
Publication
First Author: Lampert F
Year: 2011
Journal: Nat Rev Mol Cell Biol
Title: A blueprint for kinetochores - new insights into the molecular mechanics of cell division.
Volume: 12
Issue: 7
Pages: 407-12
Publication
First Author: Varma D
Year: 2012
Journal: J Cell Sci
Title: The KMN protein network--chief conductors of the kinetochore orchestra.
Volume: 125
Issue: Pt 24
Pages: 5927-36
Publication      
First Author: Overbeek PA
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Overbeek Lentiviral Transgenic Lines
Publication      
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Tromer E
Year: 2015
Journal: Genome Biol Evol
Title: Widespread Recurrent Patterns of Rapid Repeat Evolution in the Kinetochore Scaffold KNL1.
Volume: 7
Issue: 8
Pages: 2383-93
Protein Domain
Type: Repeat
Description: The outer kinetochore protein scaffold KNL1 is crucial for a correct chromosome segregation during mitosis and meiosis. The main characteristic of KNL1 is the presence of repeats containing MELT (Met-Glu-Leu-Thr) motifs which are phosphorylated and critical for the BUB1-BUB3 dimer recruitment. BUB1-BUB3 dimer regulates chromosome biorientation and the spindle assembly checkpoint [, ]. This entry mainly represents vertebrate proteins although MELT motifs are found much more widely.
Protein
Organism: Mus musculus/domesticus
Length: 1612  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Protein
Organism: Mus musculus/domesticus
Length: 2119  
Fragment?: false
Publication
First Author: Cheeseman IM
Year: 2008
Journal: Mol Biol Cell
Title: KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates.
Volume: 19
Issue: 2
Pages: 587-94