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Search results 1 to 100 out of 2877 for Kras

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Type Details Score
Gene
key_1584448 | Kras
Type: gene
Organism: Not Specified
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Gene
3845 | KRAS
Type: gene
Organism: human
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Gene
403871 | KRAS
Type: gene
Organism: dog, domestic
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Gene
541140 | KRAS
Type: gene
Organism: cattle
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Gene
418207 | KRAS
Type: gene
Organism: chicken
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Gene
707977 | KRAS
Type: gene
Organism: macaque, rhesus
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Gene
24525 | Kras
Type: gene
Organism: rat
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Gene
473387 | KRAS
Type: gene
Organism: chimpanzee
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Gene
445289 | kras
Type: gene
Organism: zebrafish
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Gene
493396 | kras
Type: gene
Organism: frog, western clawed
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Protein Coding Gene
MGI:96680 | Kras
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
3844 | KRASP1
Type: gene
Organism: human
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Publication
- | J:140469
     
First Author: Jacks T
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of a conditional mutant Kras allele
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Publication
6474169 | J:7577
First Author: Guerrero I
Year: 1984
Journal: Science
Title: Activation of a c-K-ras oncogene by somatic mutation in mouse lymphomas induced by gamma radiation.
Volume: 225
Issue: 4667
Pages: 1159-62
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Publication
6546797 | J:12009
First Author: George DL
Year: 1984
Journal: Nucleic Acids Res
Title: Amplified DNA in Y1 mouse adrenal tumor cells: isolation of cDNAs complementary to an amplified c-Ki-ras gene and localization of homologous sequences to mouse chromosome 6.
Volume: 12
Issue: 6
Pages: 2731-43
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Publication
25339352 | J:218086
First Author: Tao S
Year: 2014
Journal: Cancer Res
Title: Oncogenic KRAS confers chemoresistance by upregulating NRF2.
Volume: 74
Issue: 24
Pages: 7430-41
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Publication
28508873 | J:267092
 
First Author: Agalioti T
Year: 2017
Journal: Nat Commun
Title: Mutant KRAS promotes malignant pleural effusion formation.
Volume: 8
Pages: 15205
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Publication
26773157 | J:284551
First Author: Chen Y
Year: 2016
Journal: J Immunol
Title: Kras Is Critical for B Cell Lymphopoiesis.
Volume: 196
Issue: 4
Pages: 1678-85
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Publication
26972179 | J:238116
First Author: Damnernsawad A
Year: 2016
Journal: Stem Cells
Title: Kras is Required for Adult Hematopoiesis.
Volume: 34
Issue: 7
Pages: 1859-71
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Publication
34898002 | J:324239
First Author: Marazioti A
Year: 2022
Journal: EMBO Mol Med
Title: KRAS signaling in malignant pleural mesothelioma.
Volume: 14
Issue: 2
Pages: e13631
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Publication
18758463 | J:142964
First Author: To MD
Year: 2008
Journal: Nat Genet
Title: Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.
Volume: 40
Issue: 10
Pages: 1240-4
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Publication
1352876 | J:68954
First Author: You M
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids.
Volume: 89
Issue: 13
Pages: 5804-8
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Publication
18560355 | J:140066
First Author: Manenti G
Year: 2008
Journal: Oncogene
Title: Cis-acting genomic elements of the Pas1 locus control Kras mutability in lung tumors.
Volume: 27
Issue: 43
Pages: 5753-8
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Publication
29336889 | J:310997
First Author: Ambrogio C
Year: 2018
Journal: Cell
Title: KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS.
Volume: 172
Issue: 4
Pages: 857-868.e15
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Publication
25371176 | J:220620
First Author: Staffas A
Year: 2015
Journal: Leukemia
Title: Wild-type KRAS inhibits oncogenic KRAS-induced T-ALL in mice.
Volume: 29
Issue: 5
Pages: 1032-40
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Publication
19296721 | J:149615
First Author: Sabnis AJ
Year: 2009
Journal: PLoS Biol
Title: Oncogenic Kras initiates leukemia in hematopoietic stem cells.
Volume: 7
Issue: 3
Pages: e59
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Publication
36238685 | J:329932
 
First Author: Minati MA
Year: 2022
Journal: Front Cell Dev Biol
Title: KRAS protein expression becomes progressively restricted during embryogenesis and in adulthood.
Volume: 10
Pages: 995013
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Publication
37931288 | J:345354
First Author: Li Z
Year: 2024
Journal: Cancer Discov
Title: Alveolar Differentiation Drives Resistance to KRAS Inhibition in Lung Adenocarcinoma.
Volume: 14
Issue: 2
Pages: 308-325
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Publication
26289340 | J:254087
 
First Author: Fu Y
Year: 2015
Journal: Sci Rep
Title: Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype.
Volume: 5
Pages: 13347
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Publication
19351816 | J:147732
First Author: Miller KA
Year: 2009
Journal: Cancer Res
Title: Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo.
Volume: 69
Issue: 8
Pages: 3689-94
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Publication
29364867 | J:257934
First Author: Mueller S
Year: 2018
Journal: Nature
Title: Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Volume: 554
Issue: 7690
Pages: 62-68
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Publication
21451123 | J:170811
First Author: Lyubynska N
Year: 2011
Journal: Sci Transl Med
Title: A MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice.
Volume: 3
Issue: 76
Pages: 76ra27
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Publication
29500885 | J:280434
First Author: Borrego A
Year: 2018
Journal: Mol Carcinog
Title: Germline control of somatic Kras mutations in mouse lung tumors.
Volume: 57
Issue: 6
Pages: 745-751
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Publication
23483557 | J:198389
First Author: Marsh V
Year: 2013
Journal: J Pathol
Title: PTEN loss and KRAS activation cooperate in murine biliary tract malignancies.
Volume: 230
Issue: 2
Pages: 165-73
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Publication
28242811 | J:243132
First Author: Mustachio LM
Year: 2017
Journal: Mol Cancer Res
Title: Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer.
Volume: 15
Issue: 7
Pages: 905-914
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Publication
27984728 | J:238055
First Author: Grabocka E
Year: 2016
Journal: Cell
Title: Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules.
Volume: 167
Issue: 7
Pages: 1803-1813.e12
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Publication
22541435 | J:186194
First Author: Ying H
Year: 2012
Journal: Cell
Title: Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Volume: 149
Issue: 3
Pages: 656-70
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Publication
33859191 | J:306085
First Author: Wang X
Year: 2021
Journal: Nat Commun
Title: SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer.
Volume: 12
Issue: 1
Pages: 2259
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Publication
21075310 | J:166831
First Author: Lee KE
Year: 2010
Journal: Cancer Cell
Title: Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells.
Volume: 18
Issue: 5
Pages: 448-58
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Publication
28108627 | J:239371
First Author: Liang C
Year: 2017
Journal: Mol Cancer Res
Title: Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Volume: 15
Issue: 2
Pages: 201-212
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Publication
36928090 | J:334559
 
First Author: Salmón M
Year: 2023
Journal: J Clin Invest
Title: Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas.
Volume: 133
Issue: 7
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Publication
26909577 | J:229666
First Author: Kerr EM
Year: 2016
Journal: Nature
Title: Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities.
Volume: 531
Issue: 7592
Pages: 110-3
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Publication
23226501 | J:195686
First Author: Collins MA
Year: 2012
Journal: PLoS One
Title: Metastatic pancreatic cancer is dependent on oncogenic Kras in mice.
Volume: 7
Issue: 12
Pages: e49707
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Publication
33110094 | J:298959
First Author: Cáceres M
Year: 2020
Journal: Sci Rep
Title: Pancreatic duct ligation reduces premalignant pancreatic lesions in a Kras model of pancreatic adenocarcinoma in mice.
Volume: 10
Issue: 1
Pages: 18344
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Publication
23183424 | J:196917
First Author: Tang P
Year: 2013
Journal: Leukemia
Title: Differential roles of Kras and Pten in murine leukemogenesis.
Volume: 27
Issue: 5
Pages: 1210-4
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Publication
33079429 | J:305175
First Author: Cobo I
Year: 2021
Journal: J Pathol
Title: Epithelial Nr5a2 heterozygosity cooperates with mutant Kras in the development of pancreatic cystic lesions.
Volume: 253
Issue: 2
Pages: 174-185
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Publication
27775074 | J:241262
First Author: Ambrogio C
Year: 2017
Journal: Oncogene
Title: In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma.
Volume: 36
Issue: 16
Pages: 2309-2318
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Publication
33602788 | J:306509
First Author: Assi M
Year: 2021
Journal: Cancer Res
Title: Dynamic Regulation of Expression of KRAS and Its Effectors Determines the Ability to Initiate Tumorigenesis in Pancreatic Acinar Cells.
Volume: 81
Issue: 10
Pages: 2679-2689
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Publication
16169155 | J:104888
First Author: Deramaudt T
Year: 2005
Journal: Biochim Biophys Acta
Title: Mutant KRAS in the initiation of pancreatic cancer.
Volume: 1756
Issue: 2
Pages: 97-101
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Publication
25394415 | J:223079
 
First Author: Huang L
Year: 2014
Journal: Nat Commun
Title: Decreased tumorigenesis in mice with a Kras point mutation at C118.
Volume: 5
Pages: 5410
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Publication
28215705 | J:239669
First Author: Burgess MR
Year: 2017
Journal: Cell
Title: KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer.
Volume: 168
Issue: 5
Pages: 817-829.e15
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Publication
37768068 | J:343569
First Author: Hsu WH
Year: 2023
Journal: Cancer Discov
Title: Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression.
Volume: 13
Issue: 12
Pages: 2652-2673
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Publication
36069770 | J:328899
   
First Author: Le Roux Ö
Year: 2022
Journal: Elife
Title: Genetically manipulating endogenous Kras levels and oncogenic mutations in vivo influences tissue patterning of murine tumorigenesis.
Volume: 11
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Publication
25280562 | J:217187
First Author: Saud SM
Year: 2014
Journal: Carcinogenesis
Title: Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression.
Volume: 35
Issue: 12
Pages: 2778-86
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Publication
36060690 | J:328333
 
First Author: Sun P
Year: 2022
Journal: Front Physiol
Title: Aberrant activation of KRAS in mouse theca-interstitial cells results in female infertility.
Volume: 13
Pages: 991719
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Publication
33674596 | J:304975
First Author: Ischenko I
Year: 2021
Journal: Nat Commun
Title: KRAS drives immune evasion in a genetic model of pancreatic cancer.
Volume: 12
Issue: 1
Pages: 1482
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Publication
37407562 | J:337993
First Author: Kostyrko K
Year: 2023
Journal: Nat Commun
Title: UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma.
Volume: 14
Issue: 1
Pages: 3966
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UniProt Feature
UniProt Feature
Begin: 1
Description: GTPase KRas
Type: chain
End: 186
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Publication
26028035 | J:315938
First Author: Cisowski J
Year: 2016
Journal: Oncogene
Title: Oncogene-induced senescence underlies the mutual exclusive nature of oncogenic KRAS and BRAF.
Volume: 35
Issue: 10
Pages: 1328-33
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Publication
24954535 | J:214523
First Author: Kapoor A
Year: 2014
Journal: Cell
Title: Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer.
Volume: 158
Issue: 1
Pages: 185-197
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Publication
31390567 | J:286167
First Author: Johnson CW
Year: 2019
Journal: Cell Rep
Title: Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D.
Volume: 28
Issue: 6
Pages: 1538-1550.e7
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Publication
30786019 | J:278178
First Author: Leung EL
Year: 2019
Journal: Int J Cancer
Title: Identification of a new inhibitor of KRAS-PDEδ interaction targeting KRAS mutant nonsmall cell lung cancer.
Volume: 145
Issue: 5
Pages: 1334-1345
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Publication
38168062 | J:344083
First Author: Najumudeen AK
Year: 2024
Journal: Nat Commun
Title: KRAS allelic imbalance drives tumour initiation yet suppresses metastasis in colorectal cancer in vivo.
Volume: 15
Issue: 1
Pages: 100
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Publication
23825691 | J:203738
First Author: Mullins CD
Year: 2013
Journal: PLoS One
Title: Germinal center B-cells resist transformation by Kras independently of tumor suppressor Arf.
Volume: 8
Issue: 6
Pages: e67941
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Publication
31413817 | J:317025
First Author: Strand MS
Year: 2019
Journal: Oncotarget
Title: Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles.
Volume: 10
Issue: 46
Pages: 4761-4775
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Publication
14681207 | J:87196
First Author: Aguirre AJ
Year: 2003
Journal: Genes Dev
Title: Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.
Volume: 17
Issue: 24
Pages: 3112-26
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Publication
29191600 | J:278491
 
First Author: Liu J
Year: 2017
Journal: Lung Cancer
Title: Mig-6 deficiency cooperates with oncogenic Kras to promote mouse lung tumorigenesis.
Volume: 112
Pages: 47-56
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Publication
32127496 | J:308849
 
First Author: Kharbanda A
Year: 2020
Journal: Sci Signal
Title: Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis.
Volume: 13
Issue: 621
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Publication
26592447 | J:228016
First Author: Bailey JM
Year: 2016
Journal: Oncogene
Title: p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells.
Volume: 35
Issue: 32
Pages: 4282-8
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Publication
20215346 | J:158679
First Author: Pan Y
Year: 2010
Journal: Development
Title: Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development.
Volume: 137
Issue: 7
Pages: 1085-93
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Publication
29279356 | J:257830
First Author: Chen PY
Year: 2018
Journal: Cancer Res
Title: Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells.
Volume: 78
Issue: 4
Pages: 985-1002
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Publication
31315887 | J:278706
First Author: Chen P
Year: 2019
Journal: J Immunol
Title: Efficient CD4Cre-Mediated Conditional KRas Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis.
Volume: 203
Issue: 5
Pages: 1208-1217
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Publication
24505083 | J:210173
First Author: Hähnel PS
Year: 2014
Journal: Blood
Title: Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy.
Volume: 123
Issue: 15
Pages: 2355-66
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Publication
19028876 | J:142188
First Author: De La O JP
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia.
Volume: 105
Issue: 48
Pages: 18907-12
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Publication
20944652 | J:180850
First Author: Mukhopadhyay A
Year: 2011
Journal: J Invest Dermatol
Title: Activated Kras alters epidermal homeostasis of mouse skin, resulting in redundant skin and defective hair cycling.
Volume: 131
Issue: 2
Pages: 311-9
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Publication
24213574 | J:216272
First Author: Ye H
Year: 2014
Journal: Oncogene
Title: Synergistic function of Kras mutation and HBx in initiation and progression of hepatocellular carcinoma in mice.
Volume: 33
Issue: 43
Pages: 5133-8
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Publication
32571902 | J:299302
 
First Author: Bangs FK
Year: 2020
Journal: Dis Model Mech
Title: Ciliogenesis and Hedgehog signalling are suppressed downstream of KRAS during acinar-ductal metaplasia in mouse.
Volume: 13
Issue: 7
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Publication
24293351 | J:208067
First Author: Davies EJ
Year: 2014
Journal: J Pathol
Title: PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine.
Volume: 233
Issue: 1
Pages: 27-38
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Publication
37270580 | J:337541
First Author: Miller P
Year: 2023
Journal: Cell Death Differ
Title: p53 inhibitor iASPP is an unexpected suppressor of KRAS and inflammation-driven pancreatic cancer.
Volume: 30
Issue: 7
Pages: 1619-1635
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Publication
38402201 | J:345590
First Author: Zhu H
Year: 2024
Journal: Nat Commun
Title: Fusobacterium nucleatum promotes tumor progression in KRAS p.G12D-mutant colorectal cancer by binding to DHX15.
Volume: 15
Issue: 1
Pages: 1688
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Publication
27055865 | J:232797
First Author: Kong G
Year: 2016
Journal: Leukemia
Title: Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis.
Volume: 30
Issue: 7
Pages: 1542-51
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Publication
23453624 | J:197054
First Author: Eser S
Year: 2013
Journal: Cancer Cell
Title: Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
Volume: 23
Issue: 3
Pages: 406-20
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Publication
29316436 | J:253742
First Author: Gwinn DM
Year: 2018
Journal: Cancer Cell
Title: Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase.
Volume: 33
Issue: 1
Pages: 91-107.e6
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Publication
32891189 | J:306080
First Author: Dost AFM
Year: 2020
Journal: Cell Stem Cell
Title: Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells.
Volume: 27
Issue: 4
Pages: 663-678.e8
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Publication
29233960 | J:254092
First Author: Winters IP
Year: 2017
Journal: Nat Commun
Title: Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity.
Volume: 8
Issue: 1
Pages: 2053
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Publication
26541605 | J:299365
First Author: Yun J
Year: 2015
Journal: Science
Title: Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Volume: 350
Issue: 6266
Pages: 1391-6
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Publication
22805308 | J:191340
First Author: Cai H
Year: 2012
Journal: Cancer Res
Title: Collaboration of Kras and androgen receptor signaling stimulates EZH2 expression and tumor-propagating cells in prostate cancer.
Volume: 72
Issue: 18
Pages: 4672-81
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Publication
23712558 | J:203351
First Author: Hocker JR
Year: 2013
Journal: Int J Cancer
Title: Mass profiling of serum to distinguish mice with pancreatic cancer induced by a transgenic Kras mutation.
Volume: 133
Issue: 11
Pages: 2662-71
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Publication
28754906 | J:253051
First Author: Yoo JY
Year: 2017
Journal: Sci Rep
Title: KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance.
Volume: 7
Issue: 1
Pages: 6765
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Publication
23610445 | J:198447
First Author: Satoh H
Year: 2013
Journal: Cancer Res
Title: Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis.
Volume: 73
Issue: 13
Pages: 4158-68
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Publication
23673656 | J:331310
First Author: Kong G
Year: 2013
Journal: J Biol Chem
Title: Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation.
Volume: 288
Issue: 25
Pages: 18219-27
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Publication
36413402 | J:332817
 
First Author: Hu H
Year: 2023
Journal: J Clin Invest
Title: Oncogenic KRAS signaling drives evasion of innate immune surveillance in lung adenocarcinoma by activating CD47.
Volume: 133
Issue: 2
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Publication
12727811 | J:83055
First Author: Grippo PJ
Year: 2003
Journal: Cancer Res
Title: Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice.
Volume: 63
Issue: 9
Pages: 2016-9
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Publication
22140463 | J:181133
First Author: Carrière C
Year: 2011
Journal: PLoS One
Title: Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage.
Volume: 6
Issue: 11
Pages: e27725
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Publication
22589274 | J:189307
First Author: Kelber JA
Year: 2012
Journal: Cancer Res
Title: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer.
Volume: 72
Issue: 10
Pages: 2554-64
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Publication
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First Author: Cheng R
Year: 2023
Journal: Cell Res
Title: A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers.
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Pages: 30-45
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First Author: Lin YK
Year: 2018
Journal: Cancer Lett
Title: Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy.
Volume: 421
Pages: 161-169
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First Author: Janssen KP
Year: 2006
Journal: Gastroenterology
Title: APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression.
Volume: 131
Issue: 4
Pages: 1096-109
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First Author: Janardhan HP
Year: 2020
Journal: J Exp Med
Title: KRAS or BRAF mutations cause hepatic vascular cavernomas treatable with MAP2K-MAPK1 inhibition.
Volume: 217
Issue: 7
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First Author: Ikenoue T
Year: 2016
Journal: Sci Rep
Title: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.
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